Non-coding RNA at the Frontier of Early Diagnosis, Prognosis Evaluation, and Cancer Treatments

Non-coding RNAs (ncRNAs), such as lncRNAs, circRNAs, miRNAs, are involved in practically all aspects of cancer progression. These ncRNAs show significant differential expression pattern in both biofluids and tissue samples of patients. The biofluids can be easily and reproducibly collected for analyses. The rapid advances in high-throughput sequencing technologies and bioinformatics have further helped the development of ncRNA-based therapeutic strategy and diagnostic tests used by clinicians. This special issue focuses on the clinical aspects of ncRNAs, in particular validation of novel biomarkers that may serve as signature for non-invasive early detection of cancerous cells, predict patients' prognosis and response to specific therapies.

Submission deadline: 07/07/2024