Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies

  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
April 2013 Volume 5 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
April 2013 Volume 5 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Purulent bullous epidermal necrolysis: A potential new clinical pattern of drug eruption

  • Authors:
    • Lun‑Fei Liu
    • Jian‑Liang Yan
    • Jian‑You Wang
    • Ji‑Su Chen
    • Sui‑Qing Cai
    • Li‑Min Lao
    • Min Zheng

  • View Affiliations

    Affiliations: Department of Dermatology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, P.R. China
  • Published online on: February 1, 2013     https://doi.org/10.3892/etm.2013.944
  • Pages: 1040-1042
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Drug eruption is a major problem of adverse drug reactions and may present as variform clinical manifestations. Toxic epidermal necrolysis (TEN) and acute generalized exanthematous pustulosis (AGEP) are relatively rare severe drug eruptions. It has rarely been reported that AGEP overlaps or mimics TEN, while no purulent bullous epidermal necrolysis has been reported. The present study reports a rare case of an adult female patient with the clinical manifestations of purulent bulla and epidermal necrolysis caused by drug ingestion. The case is discussed to reveal whether a new clinical pattern of drug eruption has been identified.
View Figures

Figure 1

View References

1 

Mockenhaupt M: Severe drug-induced skin reactions: clinical pattern, diagnostics and therapy. J Dtsch Dermatol Ges. 7:142–160. 2009.(In English and German).

2 

Grover S: Severe cutaneous adverse reactions. Indian J Dermatol Venereol Leprol. 77:3–6. 2011. View Article : Google Scholar

3 

Sidoroff A, Halevy S, Bavinck JN, Vaillant L and Roujeau JC: Acute generalized exanthematous pustulosis (AGEP) - a clinical reaction pattern. J Cutan Pathol. 28:113–119. 2001. View Article : Google Scholar : PubMed/NCBI

4 

Goh TK, Pang SM, Thirumoorthy T and Goh SG: Acute generalised exanthematous pustulosis and toxic epidermal necrolysis induced by carbamazepine. Singapore Med J. 49:507–510. 2008.PubMed/NCBI

5 

Roujeau JC, Bioulac-Sage P, Bourseau C, et al: Acute generalized exanthematous pustulosis. Analysis of 63 cases. Arch Dermatol. 127:1333–1338. 1991. View Article : Google Scholar : PubMed/NCBI

6 

Leenutaphong V, Sivayathorn A, Suthipinittharm P and Sunthonpalin P: Stevens-Johnson syndrome and toxic epidermal necrolysis in Thailand. Int J Dermatol. 32:428–431. 1993. View Article : Google Scholar : PubMed/NCBI

7 

Roujeau JC, Kelly JP, Naldi L, et al: Medication use and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis. N Engl J Med. 333:1600–1607. 1995. View Article : Google Scholar : PubMed/NCBI

8 

Polilov MI: Lyell’s syndrome caused by antitetanus serum. Vestn Dermatol Venerol. 39:83–84. 1965.(In Russian).

9 

Torres MJ, Mayorga C and Blanca M: Non-immediate allergic reactions induced by drugs: pathogenesis and diagnostic tests. J Investig Allergol Clin Immunol. 19:80–90. 2009.PubMed/NCBI

10 

Romano A, Di Fonso M, Papa G, et al: Evaluation of adverse cutaneous reactions to aminopenicillins with emphasis on those manifested by maculopapular rashes. Allergy. 50:113–118. 1995. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Liu LF, Yan JL, Wang JY, Chen JS, Cai SQ, Lao LM and Zheng M: Purulent bullous epidermal necrolysis: A potential new clinical pattern of drug eruption. Exp Ther Med 5: 1040-1042, 2013.
APA
Liu, L., Yan, J., Wang, J., Chen, J., Cai, S., Lao, L., & Zheng, M. (2013). Purulent bullous epidermal necrolysis: A potential new clinical pattern of drug eruption. Experimental and Therapeutic Medicine, 5, 1040-1042. https://doi.org/10.3892/etm.2013.944
MLA
Liu, L., Yan, J., Wang, J., Chen, J., Cai, S., Lao, L., Zheng, M."Purulent bullous epidermal necrolysis: A potential new clinical pattern of drug eruption". Experimental and Therapeutic Medicine 5.4 (2013): 1040-1042.
Chicago
Liu, L., Yan, J., Wang, J., Chen, J., Cai, S., Lao, L., Zheng, M."Purulent bullous epidermal necrolysis: A potential new clinical pattern of drug eruption". Experimental and Therapeutic Medicine 5, no. 4 (2013): 1040-1042. https://doi.org/10.3892/etm.2013.944
Copy and paste a formatted citation
x
Spandidos Publications style
Liu LF, Yan JL, Wang JY, Chen JS, Cai SQ, Lao LM and Zheng M: Purulent bullous epidermal necrolysis: A potential new clinical pattern of drug eruption. Exp Ther Med 5: 1040-1042, 2013.
APA
Liu, L., Yan, J., Wang, J., Chen, J., Cai, S., Lao, L., & Zheng, M. (2013). Purulent bullous epidermal necrolysis: A potential new clinical pattern of drug eruption. Experimental and Therapeutic Medicine, 5, 1040-1042. https://doi.org/10.3892/etm.2013.944
MLA
Liu, L., Yan, J., Wang, J., Chen, J., Cai, S., Lao, L., Zheng, M."Purulent bullous epidermal necrolysis: A potential new clinical pattern of drug eruption". Experimental and Therapeutic Medicine 5.4 (2013): 1040-1042.
Chicago
Liu, L., Yan, J., Wang, J., Chen, J., Cai, S., Lao, L., Zheng, M."Purulent bullous epidermal necrolysis: A potential new clinical pattern of drug eruption". Experimental and Therapeutic Medicine 5, no. 4 (2013): 1040-1042. https://doi.org/10.3892/etm.2013.944
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team