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Case Report Open Access

Systemic lupus erythematosus with hypothyroidism as the initial clinical manifestation: A case report

  • Authors:
    • Xuejiao Zhang
    • Baofeng Xu
    • Ziwei Liu
    • Yuanyuan Gao
    • Qing Wang
    • Rui Liu
  • View Affiliations / Copyright

    Affiliations: Department of Endocrinology, China‑Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. China, Department of Neurosurgery, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China, Department of VIP Unit, China‑Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. China
    Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 996-1002
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    Published online on: May 25, 2020
       https://doi.org/10.3892/etm.2020.8788
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Abstract

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease and hypothyroidism is an organ‑specific autoimmune disease. The two diseases may occur successively or simultaneously. The majority of previous studies observed that thyroid disease was more frequent in patients with SLE than in the general population, particularly those who had a higher incidence of anti‑thyroid antibodies. However, there are no reported cases of SLE with hypothyroidism as the initial clinical manifestation, to the best of our knowledge. The present study reported on a case of SLE with this unusual initial clinical manifestation and reviewed the literature to estimate the prevalence of clinical hypothyroidism in patients with SLE (range, 3.0‑21.4%). The case of the present study had no obvious facial erythema, photosensitivity or recurrent oral ulcers, and only had hypothyroidism as the initial clinical symptom, but the laboratory examination supported the diagnosis of SLE. The present study suggested that in the clinical diagnosis, attention should be paid to screening for connective tissue diseases when diagnosing hypothyroidism, and the importance of thyroid dysfunction should also be recognized in the treatment of SLE.
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Copy and paste a formatted citation
Spandidos Publications style
Zhang X, Xu B, Liu Z, Gao Y, Wang Q and Liu R: Systemic lupus erythematosus with hypothyroidism as the initial clinical manifestation: A case report. Exp Ther Med 20: 996-1002, 2020.
APA
Zhang, X., Xu, B., Liu, Z., Gao, Y., Wang, Q., & Liu, R. (2020). Systemic lupus erythematosus with hypothyroidism as the initial clinical manifestation: A case report. Experimental and Therapeutic Medicine, 20, 996-1002. https://doi.org/10.3892/etm.2020.8788
MLA
Zhang, X., Xu, B., Liu, Z., Gao, Y., Wang, Q., Liu, R."Systemic lupus erythematosus with hypothyroidism as the initial clinical manifestation: A case report". Experimental and Therapeutic Medicine 20.2 (2020): 996-1002.
Chicago
Zhang, X., Xu, B., Liu, Z., Gao, Y., Wang, Q., Liu, R."Systemic lupus erythematosus with hypothyroidism as the initial clinical manifestation: A case report". Experimental and Therapeutic Medicine 20, no. 2 (2020): 996-1002. https://doi.org/10.3892/etm.2020.8788
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang X, Xu B, Liu Z, Gao Y, Wang Q and Liu R: Systemic lupus erythematosus with hypothyroidism as the initial clinical manifestation: A case report. Exp Ther Med 20: 996-1002, 2020.
APA
Zhang, X., Xu, B., Liu, Z., Gao, Y., Wang, Q., & Liu, R. (2020). Systemic lupus erythematosus with hypothyroidism as the initial clinical manifestation: A case report. Experimental and Therapeutic Medicine, 20, 996-1002. https://doi.org/10.3892/etm.2020.8788
MLA
Zhang, X., Xu, B., Liu, Z., Gao, Y., Wang, Q., Liu, R."Systemic lupus erythematosus with hypothyroidism as the initial clinical manifestation: A case report". Experimental and Therapeutic Medicine 20.2 (2020): 996-1002.
Chicago
Zhang, X., Xu, B., Liu, Z., Gao, Y., Wang, Q., Liu, R."Systemic lupus erythematosus with hypothyroidism as the initial clinical manifestation: A case report". Experimental and Therapeutic Medicine 20, no. 2 (2020): 996-1002. https://doi.org/10.3892/etm.2020.8788
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