Esophageal cancer presenting as a brain metastasis: A case report

  • Authors:
    • Aldo Spallone
    • Chiara Izzo
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  • Published online on: July 3, 2013     https://doi.org/10.3892/ol.2013.1436
  • Pages: 722-724
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Abstract

Carcinoma of unknown primary origin (CUP) is defined as the histological diagnosis of metastasis without the detection of a primary tumor. The incidence of CUP in all patients with a malignant disease has been reported to be between 3 and 15%. Esophageal cancer is the third most common type of cancer of the digestive tract and the seventh most common cause of cancer-related mortality worldwide. The overall incidence of the disease is highest in males >50 years old. Brain metastases have been reported in only 1.7-3.6% of all patients with different types of esophageal cancer. Brain metastasis as the presenting form of esophageal carcinoma is highly uncommon. The present study reports the case of a patient with an unknown primary tumor who presented with a cerebral metastasis, without extra‑neurological symptoms. The CUP was subsequently diagnosed as an esophageal carcinoma.
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September 2013
Volume 6 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Spallone A and Spallone A: Esophageal cancer presenting as a brain metastasis: A case report. Oncol Lett 6: 722-724, 2013
APA
Spallone, A., & Spallone, A. (2013). Esophageal cancer presenting as a brain metastasis: A case report. Oncology Letters, 6, 722-724. https://doi.org/10.3892/ol.2013.1436
MLA
Spallone, A., Izzo, C."Esophageal cancer presenting as a brain metastasis: A case report". Oncology Letters 6.3 (2013): 722-724.
Chicago
Spallone, A., Izzo, C."Esophageal cancer presenting as a brain metastasis: A case report". Oncology Letters 6, no. 3 (2013): 722-724. https://doi.org/10.3892/ol.2013.1436