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Article

Clinical characteristics of patients with large and deep soft tissue sarcomas

  • Authors:
    • Tomoki Nakamura
    • Akihiko Matsumine
    • Takao Matsubara
    • Kunihiro Asanuma
    • Astumasa Uchida
    • Akihiro Sudo

  • View Affiliations / Copyright

    Affiliations: Department of Orthopaedic Surgery, Mie University Hospital, Tsu, Mie 514‑8507, Japan
  • Pages: 841-844
    |
    Published online on: May 28, 2015
       https://doi.org/10.3892/ol.2015.3289
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Abstract

In the present study, the incidence of surgical wound complications in patients with large and deep high‑grade soft tissue sarcoma (STS) was investigated. In addition, the disease‑specific and event‑free survival rates were examined in these patients. In total, 30 adult patients with primary high‑grade deep STS with a size of 10 cm or greater were treated in the current study. Of the 30 patients, 16 (53%) developed a total of 19 wound complications. In addition, 10 cases of wound dehiscence, 5 cases of infections, 3 cases of hematomas and 1 case of lymphorrhea were reported, while 3 patients with postoperative infections underwent additional surgical treatment. Longer surgery duration was associated with wound complications (P=0.04). The disease‑specific survival was 58.5% at 3 years and 46.1% at 5 years after treatment. Furthermore, local recurrence was detected in 13 patients and distant metastasis was identified in 17 patients as the first relapse. The 3‑ and 5‑year event‑free survival rates were 24.4 and 16.3%, respectively. In conclusion, patients with large and high‑grade, deep STSs presented a high complication rate; therefore, careful wound care is required in these patients. Furthermore, it should be also taken into account that these patients have a greater risk of tumor‑associated events and mortality.
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1 

Kneisl JS, Coleman MM and Raut CP: Outcome in the management of adult soft tissue sarcomas. J Surg Oncol. 110:527–538. 2014. View Article : Google Scholar : PubMed/NCBI

2 

Grimer RJ: Size matters for sarcomas! Ann R Coll Surg Engl. 88:519–524. 2006. View Article : Google Scholar : PubMed/NCBI

3 

Nakamura T, Matsumine A, Matsubara T, et al: The symptom-to diagnosis delay in soft tissue sarcoma influence the overall survival and the development of distant metastasis. J Surg Oncol. 104:771–775. 2011. View Article : Google Scholar : PubMed/NCBI

4 

Matsubara T, Kusuzaki K, Matsumine A, Nakamura T and Sudo A: Can a less radical surgery using photodynamic therapy with acridine orange be equal to a wide-margin resection? Clin Orthop Relat Res. 471:792–802. 2013. View Article : Google Scholar : PubMed/NCBI

5 

Saddegh MK and Bauer HC: Wound complication in surgery of soft tissue sarcoma. Analysis of 103 consecutive patients managed without adjuvant therapy. Clin Orthop Relat Res. 289:247–253. 1993.PubMed/NCBI

6 

Aded R and Younge D: Surgical management of very large musculoskeletal sarcomas. Ann N Y Acad Sci. 1138:77–83. 2008. View Article : Google Scholar : PubMed/NCBI

7 

Geller DS, Hornicek FJ, Mankin HJ and Raskin KA: Soft tissue sarcoma resection volume associated with wound-healing complications. Clin Orthop Relat Res. 459:182–185. 2007. View Article : Google Scholar : PubMed/NCBI

8 

Schwartz A, Rebecca A, Smith A, et al: Risk factors for significant wound complications following wide resection of extremity soft tissue sarcomas. Clin Orthop Relat Res. 471:3612–3617. 2013. View Article : Google Scholar : PubMed/NCBI

9 

Peat BG, Bell RS, Davis A, et al: Wound-healing complications after soft-tissue sarcoma surgery. Plast Reconstr Surg. 93:980–987. 1994. View Article : Google Scholar : PubMed/NCBI

10 

Pisters PW, Leung DH, Woodruff J, Shi W and Brennan MF: Analysis of prognostic factors in 1,041 patients with localized soft tissue sarcomas of the extremities. J Clin Oncol. 14:1679–1689. 1996.PubMed/NCBI

11 

Weitz J, Antonescu CR and Brennan MF: Localized extremity soft tissue sarcoma: Improved knowledge with unchanged survival over time. J Clin Oncol. 21:2719–2725. 2003. View Article : Google Scholar : PubMed/NCBI

12 

Edge SB, Byrd DR, Compton CC, et al: Soft tissue sarcomaAJCC Cancer Staging Manual. 7th. Springer; New York, NY: pp. 345–355. 2010

13 

Trojani M, Contesso G, Coindre JM, et al: Soft-tissue sarcomas of adults; study of pathological prognostic variables and definition of a histopathological grading system. Int J Cancer. 33:37–42. 1984. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Nakamura T, Matsumine A, Matsubara T, Asanuma K, Uchida A and Sudo A: Clinical characteristics of patients with large and deep soft tissue sarcomas. Oncol Lett 10: 841-844, 2015.
APA
Nakamura, T., Matsumine, A., Matsubara, T., Asanuma, K., Uchida, A., & Sudo, A. (2015). Clinical characteristics of patients with large and deep soft tissue sarcomas. Oncology Letters, 10, 841-844. https://doi.org/10.3892/ol.2015.3289
MLA
Nakamura, T., Matsumine, A., Matsubara, T., Asanuma, K., Uchida, A., Sudo, A."Clinical characteristics of patients with large and deep soft tissue sarcomas". Oncology Letters 10.2 (2015): 841-844.
Chicago
Nakamura, T., Matsumine, A., Matsubara, T., Asanuma, K., Uchida, A., Sudo, A."Clinical characteristics of patients with large and deep soft tissue sarcomas". Oncology Letters 10, no. 2 (2015): 841-844. https://doi.org/10.3892/ol.2015.3289
Copy and paste a formatted citation
x
Spandidos Publications style
Nakamura T, Matsumine A, Matsubara T, Asanuma K, Uchida A and Sudo A: Clinical characteristics of patients with large and deep soft tissue sarcomas. Oncol Lett 10: 841-844, 2015.
APA
Nakamura, T., Matsumine, A., Matsubara, T., Asanuma, K., Uchida, A., & Sudo, A. (2015). Clinical characteristics of patients with large and deep soft tissue sarcomas. Oncology Letters, 10, 841-844. https://doi.org/10.3892/ol.2015.3289
MLA
Nakamura, T., Matsumine, A., Matsubara, T., Asanuma, K., Uchida, A., Sudo, A."Clinical characteristics of patients with large and deep soft tissue sarcomas". Oncology Letters 10.2 (2015): 841-844.
Chicago
Nakamura, T., Matsumine, A., Matsubara, T., Asanuma, K., Uchida, A., Sudo, A."Clinical characteristics of patients with large and deep soft tissue sarcomas". Oncology Letters 10, no. 2 (2015): 841-844. https://doi.org/10.3892/ol.2015.3289
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