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Article

Overexpression of peroxiredoxin-3 and -5 is a potential biomarker for prognosis in endometrial cancer

  • Authors:
    • Jung Mi Byun
    • Su Sun Kim
    • Ki Tae Kim
    • Mi Seon Kang
    • Dae Hoon Jeong
    • Dae Sim Lee
    • Eun Jung Jung
    • Young Nam Kim
    • Jin Han
    • In Sung Song
    • Kyoun Bok Lee
    • Moon Su Sung
  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics and Gynecology, Inje University Busan Paik Hospital, Busan 614‑735, Republic of Korea, Department of Pathology, Inje University Busan Paik Hospital, Busan 614‑735, Republic of Korea, Department of Physiology, Inje University Busan Paik Hospital, Busan 614‑735, Republic of Korea
  • Pages: 5111-5118
    |
    Published online on: January 31, 2018
       https://doi.org/10.3892/ol.2018.7909
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Abstract

Endometrial cancer is the sixth most common cancer in women worldwide. Peroxiredoxins (PRDXs) are antioxidant enzymes that serve important roles in cell differentiation, proliferation, and apoptosis. In the present study, the potential associations between PRDX expression and endometrial cancer were investigated. The expression levels of various PRDX mRNAs were detected by semi‑quantitative reverse transcription polymerase chain reaction (RT‑PCR) in endometrial cancer tissues (n=26) and normal endometrial tissues (n=10). Additionally, the expression of PRDX isoforms was immunohistochemically examined in endometrial cancer tissues and adjacent normal endometrial tissues from 42 patients. Finally, the associations between high PRDX expression levels and clinicopathological features were examined in patients with endometrial cancer. Analysis of PRDX expression in endometrial cancer tissues and normal endometrial tissues by semi‑quantitative RT‑PCR showed that all PRDX isoforms had increased expression in the endometrial cancer tissues compared with that in the normal endometrium, and the differences in the expression levels of PRDX1 and PRDX3 between cancer and normal tissues were statistically significant (P=0.0015 and P=0.0134, respectively). Additionally, analysis of PRDX expression in endometrial cancer and paired normal endometrial tissues by immunohistochemistry showed strong cytoplasmic staining of PRDX3 and PRDX5 in cancer tissues, with high PRDX3 (25/42, 59.5%) and PRDX5 (32/42, 76.2%) appearing more frequently in endometrial cancer than in normal endometrial tissues (P=0.0001 and P=0.0023, respectively). Furthermore, high expression of PRDX5 was associated with advanced‑stage endometrial cancer (P=0.0399). Although the 5‑year survival rate was marginally higher in patients with low expression of PRDX3 and PRDX5, this result was not statistically significant. In summary, PRDX3 and PRDX5 are highly expressed in endometrial cancer and could be associated with advanced stage and poor prognosis. Therefore, these proteins may potentially be used as prognostic markers for endometrial cancer.
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1 

Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D and Bray F: Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 136:E359–E386. 2015. View Article : Google Scholar : PubMed/NCBI

2 

Evans T, Sany O, Pearmain P, Ganesan R, Blann A and Sundar S: Differential trends in the rising incidence of endometrial cancer by type: Data from a UK population-based registry from 1994 to 2006. Br J Cancer. 104:1505–1510. 2011. View Article : Google Scholar : PubMed/NCBI

3 

Fei LY: Fast Stats: An interactive tool for access to SEER cancer statistics. Surveillance Research Program, National Cancer Institute; http://seer.cancer.gov/faststatsFebruary 2–2013

4 

Smith-Bindman R, Kerlikowske K, Feldstein VA, Subak L, Scheidler J, Segal M, Brand R and Grady D: Endovaginal ultrasound to exclude endometrial cancer and other endometrial abnormalities. JAMA. 280:1510–1517. 1998. View Article : Google Scholar : PubMed/NCBI

5 

Committee on Practice Bulletins-Gynecology, . Practice bulletin no. 128: Diagnosis of abnormal uterine bleeding in reproductive-aged women. Obstet Gynecol. 120:197–206. 2012. View Article : Google Scholar : PubMed/NCBI

6 

Berek JS: Novak's Gynecology. 13th. Lippincott Williams & Wilkins; Philadelphia, PA, USA: 2002

7 

Ueda Y, Enomoto T and Kimura T, Miyatake T, Yoshino K, Fujita M and Kimura T: Serum biomarkers for early detection of gynecologic cancers. Cancers (Basel). 2:1312–1327. 2010. View Article : Google Scholar : PubMed/NCBI

8 

Gadducci A, Cosio S and Genazzani AR: Tissue and serum biomarkers as prognostic variables in endometrioid-type endometrial cancer. Crit Rev Oncol Hematol. 80:181–192. 2011. View Article : Google Scholar : PubMed/NCBI

9 

Hakala A, Kacinski BM, Stanley ER, Kohorn EI, Puistola U, Risteli J, Risteli L, Tomás C and Kauppila A: Macrophage colony-stimulating factor 1, a clinically useful tumor marker in endometrial adenocarcinoma: comparison with CA 125 and the aminoterminal propeptide of type III procollagen. Am J Obstet Gynecol. 173:112–119. 1995. View Article : Google Scholar : PubMed/NCBI

10 

Takeshima N, Shimizu Y, Umezawa S, Hirai Y, Chen JT, Fujimoto I, Yamauchi K and Hasumi K: Combined assay of serum levels of CA125 and CA19-9 in endometrial carcinoma. Gynecol Oncol. 54:321–326. 1994. View Article : Google Scholar : PubMed/NCBI

11 

Baser E, Gungor T, Togrul C, Turkoglu O and Celen S: Preoperative prediction of poor prognostic parameters and adjuvant treatment in women with pure endometrioid type endometrial cancer: What is the significance of tumor markers? Eur J Gynaecol Oncol. 35:513–518. 2014.PubMed/NCBI

12 

Yasa C, Takmaz O, Dural O and Akhan SE: The value of tumor markers in endometrial carcinoma: Review of literature. Sci Res. 4:966–970. 2013.

13 

Price FV, Chambers SK, Carcangiu ML, Kohorn EI, Schwartz PE and Chambers JT: CA 125 may not reflect disease status in patients with uterine serous carcinoma. Cancer. 82:1720–1725. 1998. View Article : Google Scholar : PubMed/NCBI

14 

Kim K, Kim I, Lee KY, Rhee S and Stadtman E: The isolation and purification of a specific ‘protector’ protein which inhibits enzyme inactivation by a thiol/Fe (III)/O2 mixed-function oxidation system. J Biol Chem. 263:4704–4711. 1988.PubMed/NCBI

15 

Rhee SG: Cell signaling. H2O2, a necessary evil for cell signaling. Scienc e. 312:1882–1883. 2006.

16 

Hall A, Nelson K, Poole LB and Karplus PA: Structure-based insights into the catalytic power and conformational dexterity of peroxiredoxins. Antioxid Redox Signal. 15:795–815. 2011. View Article : Google Scholar : PubMed/NCBI

17 

Neumann CA, Cao J and Manevich Y: Peroxiredoxin 1 and its role in cell signaling. Cell Cycle. 8:4072–4078. 2009. View Article : Google Scholar : PubMed/NCBI

18 

Mu ZM, Yin XY and Prochownik EV: Pag, a putative tumor suppressor, interacts with the Myc Box II domain of c-Myc and selectively alters its biological function and target gene expression. J Biol Chem. 277:43175–43184. 2002. View Article : Google Scholar : PubMed/NCBI

19 

Yo YD, Chung YM, Park JK, Ahn CM, Kim SK and Kim HJ: Synergistic effect of peroxiredoxin II antisense on cisplatin-induced cell death. Exp Mol Med. 34:273–277. 2002. View Article : Google Scholar : PubMed/NCBI

20 

Okoh V, Deoraj A and Roy D: Estrogen-induced reactive oxygen species-mediated signalings contribute to breast cancer. Biochim Biophys Acta. 1815:115–133. 2011.PubMed/NCBI

21 

Felty Q, Xiong WC, Sun D, Sarkar S, Singh KP, Parkash J and Roy D: Estrogen-induced mitochondrial reactive oxygen species as signal-transducing messengers. Biochemistry. 44:6900–6909. 2005. View Article : Google Scholar : PubMed/NCBI

22 

Musarrat J, Arezina-Wilson J and Wani A: Prognostic and aetiological relevance of 8-hydroxyguanosine in human breast carcinogenesis. Eur J Cancer. 32A:1–1214. 1996.

23 

O'Leary PC, Terrile M, Bajor M, Gaj P, Hennessy BT, Mills GB, Zagozdzon A, O'Connor DP, Brennan DJ, Connor K, et al: Peroxiredoxin-1 protects estrogen receptor alpha from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer. Breast Cancer Res. 16:R792014. View Article : Google Scholar : PubMed/NCBI

24 

Karihtala P, Kauppila S, Soini Y and Arja-Jukkola-Vuorinen: Oxidative stress and counteracting mechanisms in hormone receptor positive, triple-negative and basal-like breast carcinomas. BMC Cancer. 11:2622011. View Article : Google Scholar : PubMed/NCBI

25 

Elamin A, Zhu H, Hassan AM, Xu N and Ibrahim ME: Peroxiredoxin V: A candidate breast tumor marker of population specificity. Mol Clin Oncol. 1:541–549. 2013. View Article : Google Scholar : PubMed/NCBI

26 

Pecorelli S: Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. Int J Gynaecol Obstet. 105:103–104. 2009. View Article : Google Scholar : PubMed/NCBI

27 

Han S, Shen H, Jung M, Hahn BS, Jin BK, Kang I, Ha J and Choe W: Expression and prognostic significance of human peroxiredoxin isoforms in endometrial cancer. Oncol Lett. 3:1275–1279. 2012. View Article : Google Scholar : PubMed/NCBI

28 

Rhee SG, Chae HZ and Kim K: Peroxiredoxins: A historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling. Free Radic Biol Med. 38:1543–1552. 2005. View Article : Google Scholar : PubMed/NCBI

29 

Wonsey DR, Zeller KI and Dang CV: The c-Myc target gene PRDX3 is required for mitochondrial homeostasis and neoplastic transformation. Proc Natl Acad Sci USA. 99:pp. 6649–6654. 2002; View Article : Google Scholar : PubMed/NCBI

30 

Knoops B, Clippe A, Bogard C, Arsalane K, Wattiez R, Hermans C, Duconseille E, Falmagne P and Bernard A: Cloning and characterization of AOEB166, a novel mammalian antioxidant enzyme of the peroxiredoxin family. J Biol Chem. 274:30451–30458. 1999. View Article : Google Scholar : PubMed/NCBI

31 

Whitaker HC, Patel D, Howat WJ, Warren AY, Kay JD, Sangan T, Marioni JC, Mitchell J, Aldridge S, Luxton HJ, et al: Peroxiredoxin-3 is overexpressed in prostate cancer and promotes cancer cell survival by protecting cells from oxidative stress. Br J Cancer. 109:983–993. 2013. View Article : Google Scholar : PubMed/NCBI

32 

Kinnula VL, Lehtonen S, Sormunen R, Kaarteenaho-Wiik R, Kang SW, Rhee SG and Soini Y: Overexpression of peroxiredoxins I, II, III, V, and VI in malignant mesothelioma. J Pathol. 196:316–323. 2002. View Article : Google Scholar : PubMed/NCBI

33 

Noh DY, Ahn SJ, Lee RA, Kim SW, Park IA and Chae HZ: Overexpression of peroxiredoxin in human breast cancer. Anticancer Res. 21:2085–2090. 2001.PubMed/NCBI

34 

Choi JH, Kim TN, Kim S, Baek SH, Kim JH, Lee SR and Kim JR: Overexpression of mitochondrial thioredoxin reductase and peroxiredoxin III in hepatocellular carcinomas. Anticancer Res. 22:3331–3335. 2002.PubMed/NCBI

35 

Nonn L, Berggren M and Powis G: Increased expression of mitochondrial peroxiredoxin-3 (Thioredoxin Peroxidase-2) protects cancer cells against hypoxia and drug-induced hydrogen peroxide-dependent. Mol Cancer Res. 1:682–689. 2003.PubMed/NCBI

36 

Kropotov A, Gogvadze V, Shupliakov O, Tomilin N, Serikov VB, Tomilin NV and Zhivotovsky B: Peroxiredoxin V is essential for protection against apoptosis in human lung carcinoma cells. Exp Cell Res. 312:2806–2815. 2006. View Article : Google Scholar : PubMed/NCBI

37 

Song IS, Kim HK, Jeong SH, Lee SR, Kim N, Rhee BD, Ko KS and Han J: Mitochondrial peroxiredoxin III is a potential target for cancer therapy. Int J Mol Sci. 12:7163–7185. 2011. View Article : Google Scholar : PubMed/NCBI

38 

Riddell JR, Wang XY, Minderman H and Gollnick SO: Peroxiredoxin 1 stimulates secretion of proinflammatory cytokines by binding to TLR4. J Immunol. 184:1022–1030. 2010. View Article : Google Scholar : PubMed/NCBI

39 

Creasman WT, Odicino F, Maisonneuve P, Quinn MA, Beller U, Benedet JL, Heintz AP, Ngan HY and Pecorelli S: Carcinoma of the corpus uteri. FIGO 26th annual report on the results of treatment in gynecological cancer. Int J Gynaecol Obstet. 95 Suppl 1:S105–S143. 2006. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Byun JM, Kim SS, Kim KT, Kang MS, Jeong DH, Lee DS, Jung EJ, Kim YN, Han J, Song IS, Song IS, et al: Overexpression of peroxiredoxin-3 and -5 is a potential biomarker for prognosis in endometrial cancer. Oncol Lett 15: 5111-5118, 2018.
APA
Byun, J.M., Kim, S.S., Kim, K.T., Kang, M.S., Jeong, D.H., Lee, D.S. ... Sung, M.S. (2018). Overexpression of peroxiredoxin-3 and -5 is a potential biomarker for prognosis in endometrial cancer. Oncology Letters, 15, 5111-5118. https://doi.org/10.3892/ol.2018.7909
MLA
Byun, J. M., Kim, S. S., Kim, K. T., Kang, M. S., Jeong, D. H., Lee, D. S., Jung, E. J., Kim, Y. N., Han, J., Song, I. S., Lee, K. B., Sung, M. S."Overexpression of peroxiredoxin-3 and -5 is a potential biomarker for prognosis in endometrial cancer". Oncology Letters 15.4 (2018): 5111-5118.
Chicago
Byun, J. M., Kim, S. S., Kim, K. T., Kang, M. S., Jeong, D. H., Lee, D. S., Jung, E. J., Kim, Y. N., Han, J., Song, I. S., Lee, K. B., Sung, M. S."Overexpression of peroxiredoxin-3 and -5 is a potential biomarker for prognosis in endometrial cancer". Oncology Letters 15, no. 4 (2018): 5111-5118. https://doi.org/10.3892/ol.2018.7909
Copy and paste a formatted citation
x
Spandidos Publications style
Byun JM, Kim SS, Kim KT, Kang MS, Jeong DH, Lee DS, Jung EJ, Kim YN, Han J, Song IS, Song IS, et al: Overexpression of peroxiredoxin-3 and -5 is a potential biomarker for prognosis in endometrial cancer. Oncol Lett 15: 5111-5118, 2018.
APA
Byun, J.M., Kim, S.S., Kim, K.T., Kang, M.S., Jeong, D.H., Lee, D.S. ... Sung, M.S. (2018). Overexpression of peroxiredoxin-3 and -5 is a potential biomarker for prognosis in endometrial cancer. Oncology Letters, 15, 5111-5118. https://doi.org/10.3892/ol.2018.7909
MLA
Byun, J. M., Kim, S. S., Kim, K. T., Kang, M. S., Jeong, D. H., Lee, D. S., Jung, E. J., Kim, Y. N., Han, J., Song, I. S., Lee, K. B., Sung, M. S."Overexpression of peroxiredoxin-3 and -5 is a potential biomarker for prognosis in endometrial cancer". Oncology Letters 15.4 (2018): 5111-5118.
Chicago
Byun, J. M., Kim, S. S., Kim, K. T., Kang, M. S., Jeong, D. H., Lee, D. S., Jung, E. J., Kim, Y. N., Han, J., Song, I. S., Lee, K. B., Sung, M. S."Overexpression of peroxiredoxin-3 and -5 is a potential biomarker for prognosis in endometrial cancer". Oncology Letters 15, no. 4 (2018): 5111-5118. https://doi.org/10.3892/ol.2018.7909
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