|
1
|
Torre LA, Trabert B, DeSantis CE, Miller
KD, Samimi G, Runowicz CD, Gaudet MM, Jemal A and Siegel RL:
Ovarian cancer statistics, 2018. CA Cancer J Clin. 68:284–296.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Wu J, Sun H, Yang L, Deng Y, Yan Y, Wang
S, Yang G and Ma H: Improved survival in ovarian cancer, with
widening survival gaps of races and socioeconomic status: A period
analysis, 1983–2012. J Cancer. 9:3548–3556. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Bartel DP: MicroRNAs: Genomics,
biogenesis, mechanism, and function. Cell. 116:281–297. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Yang N, Kaur S, Volinia S, Greshock J,
Lassus H, Hasegawa K, Liang S, Leminen A, Deng S, Smith L, et al:
MicroRNA microarray identifies Let-7i as a novel biomarker and
therapeutic target in human epithelial ovarian cancer. Cancer Res.
68:10307–10314. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Yu SL, Chen HY, Chang GC, Chen CY, Chen
HW, Singh S, Cheng CL, Yu CJ, Lee YC, Chen HS, et al: MicroRNA
signature predicts survival and relapse in lung cancer. Cancer
Cell. 13:48–57. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Weidhaas JB, Babar I, Nallur SM, Trang P,
Roush S, Boehm M, Gillespie E and Slack FJ: MicroRNAs as potential
agents to alter resistance to cytotoxic anticancer therapy. Cancer
Res. 67:11111–11116. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Bentwich I, Avniel A, Karov Y, Aharonov R,
Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, et al:
Identification of hundreds of conserved and nonconserved human
microRNAs. Nat Genet. 37:766–770. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Backes C and Keller A: Reanalysis of 3,707
novel human microRNA candidates. Proc Natl Acad Sci USA.
112:E2849–E2850. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Volinia S, Calin GA, Liu CG, Ambs S,
Cimmino A, Petrocca F, Visone R, Iorio M, Roldo C, Ferracin M, et
al: A microRNA expression signature of human solid tumors defines
cancer gene targets. Proc Natl Acad Sci USA. 103:2257–2261. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Chan JA, Krichevsky AM and Kosik KS:
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells.
Cancer Res. 65:6029–6033. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Nusse R, Fuerer C, Ching W, Harnish K,
Logan C, Zeng A, ten Berge D and Kalani Y: Wnt signaling and stem
cell control. Cold Spring Harb Symp Quant Biol. 73:59–66. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Valenta T, Hausmann G and Basler K: The
many faces and functions of β-catenin. EMBO J. 31:2714–2736. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Liu J, Pan S, Hsieh MH, Ng N, Sun F, Wang
T, Kasibhatla S, Schuller AG, Li AG, Cheng D, et al: Targeting
Wnt-driven cancer through the inhibition of Porcupine by LGK974.
Proc Natl Acad Sci USA. 110:20224–20229. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Arend RC, Londoño-Joshi AI, Straughn JM Jr
and Buchsbaum DJ: The Wnt/β-catenin pathway in ovarian cancer: A
review. Gynecol Oncol. 131:772–779. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Cai X, Yao Z, Li L and Huang J: Role of
DKK4 in Tumorigenesis and Tumor Progression. Int J Biol Sci.
14:616–621. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Chau WK, Ip CK, Mak AS, Lai HC and Wong
AS: c-Kit mediates chemoresistance and tumor-initiating capacity of
ovarian cancer cells through activation of
Wnt/β-catenin-ATP-binding cassette G2 signaling. Oncogene.
32:2767–2781. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Nagel R, le Sage C, Diosdado B, van der
Waal M, Oude Vrielink JA, Bolijn A, Meijer GA and Agami R:
Regulation of the adenomatous polyposis coli gene by the miR-135
family in colorectal cancer. Cancer Res. 68:5795–5802. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Luo G, Luo W, Sun X, Lin J, Wang M and
Zhang Y, Luo W and Zhang Y: MicroRNA21 promotes migration and
invasion of glioma cells via activation of Sox2 and β-catenin
signaling. Mol Med Rep. 15:187–193. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Günthert U, Hofmann M, Rudy W, Reber S,
Zöller M, Haussmann I, Matzku S, Wenzel A, Ponta H and Herrlich P:
A new variant of glycoprotein CD44 confers metastatic potential to
rat carcinoma cells. Cell. 65:13–24. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Rudy W, Hofmann M, Schwartz-Albiez R,
Zöller M, Heider KH, Ponta H and Herrlich P: The two major CD44
proteins expressed on a metastatic rat tumor cell line are derived
from different splice variants: Each one individually suffices to
confer metastatic behavior. Cancer Res. 53:1262–1268.
1993.PubMed/NCBI
|
|
21
|
Seiter S, Arch R, Reber S, Komitowski D,
Hofmann M, Ponta H, Herrlich P, Matzku S and Zöller M: Prevention
of tumor metastasis formation by anti-variant CD44. J Exp Med.
177:443–455. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Tjhay F, Motohara T, Tayama S, Narantuya
D, Fujimoto K, Guo J, Sakaguchi I, Honda R, Tashiro H and Katabuchi
H: CD44 variant 6 is correlated with peritoneal dissemination and
poor prognosis in patients with advanced epithelial ovarian cancer.
Cancer Sci. 106:1421–1428. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Motohara T, Fujimoto K, Tayama S,
Narantuya D, Sakaguchi I, Tashiro H and Katabuchi H: CD44 variant 6
as a predictive biomarker for distant metastasis in patients with
epithelial ovarian cancer. Obstet Gynecol. 127:1003–1011. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Katoh M: Multilayered prevention and
treatment of chronic inflammation, organ fibrosis and cancer
associated with canonical WNT/β-catenin signaling activation
(Review). Int J Mol Med. 42:713–725. 2018.PubMed/NCBI
|
|
25
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Sun H, He S, Wen B, Jia W, Fan E and Zheng
Y: Effect of Biejiajian Pills on Wnt signal pathway molecules
β-catenin and GSK-3β and the target genes CD44v6 and VEGF in
hepatocellular carcinoma cells. Nan Fang Yi Ke Da Xue Xue Bao.
34:1454–1458. 2014.(In Chinese). PubMed/NCBI
|
|
27
|
Kumarswamy R, Volkmann I and Thum T:
Regulation and function of miRNA-21 in health and disease. RNA
Biol. 8:706–713. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Bonci D: MicroRNA-21 as therapeutic target
in cancer and cardiovascular disease. Recent Pat Cardiovasc Drug
Discov. 5:156–161. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Huang Y, Yang YB, Zhang XH, Yu XL, Wang ZB
and Cheng XC: MicroRNA-21 gene and cancer. Med Oncol. 30:3762013.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Vaksman O, Tropé C, Davidson B and Reich
R: Exosome-derived miRNAs and ovarian carcinoma progression.
Carcinogenesis. 35:2113–2120. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Kimura M, Nakajima-Koyama M, Lee J and
Nishida E: Transient expression of WNT2 promotes somatic cell
reprogramming by inducing β-catenin nuclear accumulation. Stem Cell
Reports. 6:834–843. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Zhan T, Rindtorff N and Boutros M: Wnt
signaling in cancer. Oncogene. 36:1461–1473. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Echevarría-Vargas IM, Valiyeva F and
Vivas-Mejía PE: Upregulation of miR-21 in cisplatin resistant
ovarian cancer via JNK-1/c-Jun pathway. PLoS One. 9:e970942014.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Zhang H, Li J, Li G and Wang S: Effects of
celastrol on enhancing apoptosis of ovarian cancer cells via the
downregulation of microRNA21 and the suppression of the
PI3K/AktNF-κB signaling pathway in an in vitro model of ovarian
carcinoma. Mol Med Rep. 14:5363–5368. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Eitan R, Kushnir M, Lithwick-Yanai G,
David MB, Hoshen M, Glezerman M, Hod M, Sabah G, Rosenwald S and
Levavi H: Tumor microRNA expression patterns associated with
resistance to platinum based chemotherapy and survival in ovarian
cancer patients. Gynecol Oncol. 114:253–259. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Cevallos RR, Rodríguez-Martínez G and
Gazarian K: Wnt/β-catenin/TCF pathway is a phase-dependent promoter
of colony formation and mesendodermal differentiation during human
somatic cell reprogramming. Stem Cells. 36:683–695. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Yu Y, Kanwar SS, Patel BB, Oh PS, Nautiyal
J, Sarkar FH and Majumdar AP: MicroRNA-21 induces stemness by
downregulating transforming growth factor beta receptor 2 (TGFβR2)
in colon cancer cells. Carcinogenesis. 33:68–76. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Wu D, Shi M and Fan XD: Mechanism of
miR-21 via Wnt/β-catenin signaling pathway in human A549 lung
cancer cells and Lewis lung carcinoma in mice. Asian Pac J Trop
Med. 8:479–484. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Yamamura S, Matsumura N, Mandai M, Huang
Z, Oura T, Baba T, Hamanishi J, Yamaguchi K, Kang HS, Okamoto T, et
al: The activated transforming growth factor-beta signaling pathway
in peritoneal metastases is a potential therapeutic target in
ovarian cancer. Int J Cancer. 130:20–28. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Schmitt M, Metzger M, Gradl D, Davidson G
and Orian-Rousseau V: CD44 functions in Wnt signaling by regulating
LRP6 localization and activation. Cell Death Differ. 22:677–689.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Wielenga VJ, van der Neut R, Offerhaus GJ
and Pals ST: CD44 glycoproteins in colorectal cancer: Expression,
function, and prognostic value. Adv Cancer Res. 77:169–187. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Todaro M, Gaggianesi M, Catalano V,
Benfante A, Iovino F, Biffoni M, Apuzzo T, Sperduti I, Volpe S,
Cocorullo G, et al: CD44v6 is a marker of constitutive and
reprogrammed cancer stem cells driving colon cancer metastasis.
Cell Stem Cell. 14:342–356. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Han J, Gao B, Jin X, Xu Z, Li Z, Sun Y and
Song B: Small interfering RNA-mediated downregulation of
beta-catenin inhibits invasion and migration of colon cancer cells
in vitro. Med Sci Monit. 18:BR273–BR280. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Gao Y, Foster R, Yang X, Feng Y, Shen JK,
Mankin HJ, Hornicek FJ, Amiji MM and Duan Z: Up-regulation of CD44
in the development of metastasis, recurrence and drug resistance of
ovarian cancer. Oncotarget. 6:9313–9326. 2015. View Article : Google Scholar : PubMed/NCBI
|
