Journal Articles

Open Access

RUNX family: Oncogenes or tumor suppressors (Review)

Beatriz Andrea Otálora‑Otálora, Berta Henríquez, Liliana López‑Kleine, Adriana Rojas

Pages: 3-19 Published online on: 06 May 2019
Open Access

The targeting of non‑coding RNAs by curcumin: Facts and hopes for cancer therapy (Review)

Yun Liu, Hongmei Sun, Bolat Makabel, Qingbin Cui, Jiajun Li, Chaoyue Su, Charles R. Ashby Jr, Zhesheng Chen, Jianye Zhang

Pages: 20-34 Published online on: 03 May 2019
Open Access

Engineered human mesenchymal stem cells for neuroblastoma therapeutics

Valentina Nieddu, Roberta Piredda, Daniel Bexell, Jack Barton, John Anderson, Neil Sebire, Krishna Kolluri, Sam M. Janes, Emmanouil Karteris, Arturo Sala

Pages: 35-42 Published online on: 08 May 2019
Open Access

Differential gene methylation patterns in cancerous and non‑cancerous cells

Katarzyna Kamińska, Aneta Białkowska, Janusz Kowalewski, Sui Huang, Marzena A. Lewandowska

Pages: 43-54 Published online on: 15 May 2019
Open Access

miR‑767‑5p inhibits glioma proliferation and metastasis by targeting SUZ12

Jiale Zhang, Shuo Xu, Jia Xu, Yangyang Li, Jie Zhang, Jian Zhang, Xiaoming Lu

Pages: 55-66 Published online on: 13 May 2019
Open Access

CtBP1 interacts with SOX2 to promote the growth, migration and invasion of lung adenocarcinoma

Yifei Liu, Tingting Bian, Jia Feng, Li Qian, Xiaoli Li, Qing Zhang, Jianguo Zhang, Daishan Jiang, Jian Liu, Jiahai Shi

Pages: 67-78 Published online on: 02 May 2019
Open Access

Cystatin F as a key family 2 cystatin subunit and prognostic biomarker for early‑stage pancreatic ductal adenocarcinoma

Chengkun Yang, Tingdong Yu, Zhengqian Liu, Xinping Ye, Xiwen Liao, Xiangkun Wang, Chuangye Han, Guangzhi Zhu, Wei Qin, Tao Peng

Pages: 79-90 Published online on: 24 April 2019
Open Access

Promotion of ovarian cancer cell invasion, migration and colony formation by the miR‑21/Wnt/CD44v6 pathway

Yanqing Wang, Xiao Yang, Mengqin Yuan, Shu Xian, Li Zhang, Dongyong Yang, Yanxiang Cheng

Pages: 91-102 Published online on: 09 May 2019
Open Access

PRP‑1 significantly decreases the ALDHhigh cancer stem cell population and regulates the aberrant Wnt/β‑catenin pathway in human chondrosarcoma JJ012 cells

A. K. Hoyt, A. Moran, C. Granger, A. Sedani, S. Saigh, J. Brown, K. A. Galoian

Pages: 103-114 Published online on: 24 May 2019
Open Access

Gene expression alterations of human liver cancer cells following borax exposure

Lun Wu, Ying Wei, Wen‑Bo Zhou, You‑Shun Zhang, Qin‑Hua Chen, Ming‑Xing Liu, Zheng‑Peng Zhu, Jiao Zhou, Li‑Hua Yang, Hong‑Mei Wang, Guang‑Min Wei, Sheng Wang, Zhi‑Gang Tang

Pages: 115-130 Published online on: 23 May 2019
Open Access

Luteolin suppresses colorectal cancer cell metastasis via regulation of the miR‑384/pleiotrophin axis

Yuanyuan Yao, Chunhui Rao, Gang Zheng, Saisai Wang

Pages: 131-141 Published online on: 24 April 2019
Open Access

LRIG1‑2 and LMO7 immunoreactivity in vulvar squamous cell carcinoma: Association with prognosis in relation to HPV‑DNA and p16INK4a status

Kristina Stefansson, Husam Oda, Charlotte Öfverman, Eva Lundin, Håkan Hedman, David Lindquist

Pages: 142-150 Published online on: 02 May 2019
Open Access

Prospective molecular mechanism of COL5A1 in breast cancer based on a microarray, RNA sequencing and immunohistochemistry

Mei Wu, Qi Sun, Chao‑Hua Mo, Jin‑Shu Pang, Jia‑Yin Hou, Ling‑Ling Pang, Hui‑Ping Lu, Yi‑Wu Dang, Su‑Jie Fang, Deng Tang, Gang Chen, Zhen‑Bo Feng

Pages: 151-175 Published online on: 03 May 2019
Open Access

Tranilast enhances the effect of anticancer agents in osteosarcoma

Takayuki Nakashima, Satoshi Nagano, Takao Setoguchi, Hiromi Sasaki, Yoshinobu Saitoh, Shingo Maeda, Setsuro Komiya, Noboru Taniguchi

Pages: 176-188 Published online on: 06 May 2019
Open Access

Investigation of the clinical significance and prospective molecular mechanisms of cystatin genes in patients with hepatitis B virus‑related hepatocellular carcinoma

Xin Zhou, Xiangkun Wang, Ketuan Huang, Xiwen Liao, Chengkun Yang, Tingdong Yu, Junqi Liu, Chuangye Han, Guangzhi Zhu, Hao Su, Wei Qin, Quanfa Han, Zhengqian Liu, Jianlv Huang, Yizhen Gong, Xinping Ye, Tao Peng

Pages: 189-201 Published online on: 09 May 2019
Open Access

HOXC10 overexpression promotes cell proliferation and migration in gastric cancer

Jina Kim, Dong‑Hyuck Bae, Jong Hwan Kim, Kyu‑Sang Song, Yong Sung Kim, Seon‑Young Kim

Pages: 202-212 Published online on: 17 May 2019
Open Access

MEIS2 promotes cell migration and invasion in colorectal cancer

Ziang Wan, Rui Chai, Hang Yuan, Bingchen Chen, Quanjin Dong, Boan Zheng, Xiaozhou Mou, Wensheng Pan, Yifeng Tu, Qing Yang, Shiliang Tu, Xinye Hu

Pages: 213-223 Published online on: 15 May 2019

Targeting lactate dehydrogenase‑A promotes docetaxel‑induced cytotoxicity predominantly in castration‑resistant prostate cancer cells

Hiroyuki Muramatsu, Makoto Sumitomo, Shingo Morinaga, Keishi Kajikawa, Ikuo Kobayashi, Genya Nishikawa, Yoshiharu Kato, Masahito Watanabe, Kenji Zennami, Kent Kanao, Kogenta Nakamura, Susumu Suzuki, Kazuhiro Yoshikawa

Pages: 224-230 Published online on: 24 May 2019

Fingolimod sensitizes EGFR wild‑type non‑small cell lung cancer cells to lapatinib or sorafenib and induces cell cycle arrest

Kohki Ota, Takashi Okuma, Alberto De Lorenzo, Ayuka Yokota, Hirotsugu Hino, Hiromi Kazama, Shota Moriya, Naoharu Takano, Masaki Hiramoto, Keisuke Miyazawa

Pages: 231-242 Published online on: 02 May 2019

125I radiation downregulates TRPV1 expression through miR‑1246 in neuroblastoma cells

Dingguo Zhang, Hongwei Xu, Yuqiong Wang, Kaixua Wang, Yuxin Wang, Bing Wu, Jianwei Zhu, Lisi Peng, Jun Gao, Zhaoshen Li

Pages: 243-252 Published online on: 22 April 2019

Expression of tesmin (MTL5) in non‑small cell lung cancer: A preliminary study

Jedrzej Grzegrzolka, Agnieszka Gomulkiewicz, Mateusz Olbromski, Natalia Glatzel‑Plucinska, Aleksandra Piotrowska, Katarzyna Ratajczak‑Wielgomas, Adam Rzechonek, Marzena Podhorska‑Okolow, Zbigniew Krawczuk, Piotr Dziegiel

Pages: 253-262 Published online on: 02 May 2019

Small RNA sequencing revealed aberrant piRNA expression profiles in colorectal cancer

Jie Yin, Wei Qi, Chen‑Guang Ji, Dong‑Xuan Zhang, Xiao‑Li Xie, Qian Ding, Xiao‑Yu Jiang, Jing Han, Hui‑Qing Jiang

Pages: 263-272 Published online on: 13 May 2019

Conditionally replicative adenovirus carrying shRNA targeting EZH2 inhibits prostate cancer growth and invasion

Shi‑Gao Xu, Jun‑Jie Yu, Qun Shi, Quan Niu, Zhe Guo, Bao‑Yu Guo, Guang‑Chen Zhou, Xiao Gu, Yin‑Xia Wu

Pages: 273-282 Published online on: 13 May 2019

Radixin knockdown improves the accumulation and efficiency of methotrexate in tumor cells

Atsushi Kawase, Yuta Inoue, Sayaka Nakazaki, Erika Koizumi, Masahiro Iwaki

Pages: 283-290 Published online on: 15 May 2019

Effects of miR‑181a on the biological function of multiple myeloma

Ni Liu, Jingyu Yang, Ruili Yuan, Jing Peng, Lina Liu, Xuan Guo

Pages: 291-300 Published online on: 15 May 2019
Open Access

Cytokeratin 18 regulates the transcription and alternative splicing of apoptotic‑related genes and pathways in HeLa cells

Yi Cheng, Kai Qin, Nan Huang, Zhipeng Zhou, Huihua Xiong, Jing Zhao, Yi Zhang, Shiying Yu

Pages: 301-312 Published online on: 22 May 2019

miR‑92a contributes to cell proliferation, apoptosis and doxorubicin chemosensitivity in gastric carcinoma cells

Xuan‑Chen Tao, Xin‑Yu Zhang, Shi‑Bo Sun, De‑Quan Wu

Pages: 313-320 Published online on: 23 May 2019

CDK6 overexpression resulted from microRNA‑320d downregulation promotes cell proliferation in diffuse large B‑cell lymphoma

Hong Su, Jiang Chang, Mengwei Xu, Ruifang Sun, Jinfen Wang

Pages: 321-327 Published online on: 02 May 2019

Pomolic acid exhibits anticancer potential against a docetaxel‑resistant PC3 prostate cell line

Carollina De Araujo Martins, Gleice Da Graça Rocha, Cerli Rocha Gattass, Christina Maeda Takiya

Pages: 328-338 Published online on: 19 April 2019

Eicosapentaenoic acid suppresses angiogenesis via reducing secretion of IL‑6 and VEGF from colon cancer‑associated fibroblasts

Nanako Ando, Masayasu Hara, Kazuyoshi Shiga, Takeshi Yanagita, Korehito Takasu, Nozomu Nakai, Yuzo Maeda, Takahisa Hirokawa, Hiroki Takahashi, Hideyuki Ishiguro, Yoichi Matsuo, Shuji Takiguchi

Pages: 339-349 Published online on: 02 May 2019

Tumor‑type‑dependent effects on the angiogenic abilities of endothelial cells in an in vitro rat cell model

Majida Al‑Abboodi, Ran An, Maximilian Weber, Rafael Schmid, Anne Klausing, Raymund E. Horch, Anja M. Boos, Annika Kengelbach‑Weigand

Pages: 350-360 Published online on: 02 May 2019

Improving lung cancer treatment: Hyaluronic acid‑modified and glutathione‑responsive amphiphilic TPGS‑doxorubicin prodrug‑entrapped nanoparticles

Guojun Lu, Lei Cao, Chenyao Zhu, Haiyan Xie, Keke Hao, Ning Xia, Bo Wang, Yu Zhang, Feng Liu

Pages: 361-369 Published online on: 02 May 2019

Intratumoral injection of dendritic cells overexpressing interleukin‑12 inhibits melanoma growth

Weirong Yao, Yingliang Li, Lin Zeng, Xiquan Zhang, Zhiyong Zhou, Meixue Zheng, Huiping Wan

Pages: 370-376 Published online on: 21 May 2019

The combination of temsirolimus and chloroquine increases radiosensitivity in colorectal cancer cells

Hiroshi Shiratori, Kazushige Kawai, Keisuke Hata, Toshiaki Tanaka, Takeshi Nishikawa, Kensuke Otani, Kazuhito Sasaki, Manabu Kaneko, Koji Murono, Shigenobu Emoto, Hirofumi Sonoda, Hiroaki Nozawa

Pages: 377-385 Published online on: 23 April 2019

Gene expression profile of cancer stem‑like cells in the SW480 colon adenocarcinoma cell line

Yuanyuan Wang, Ling Zhou, Qing Qing, Yingfei Li, Lixuan Li, Xiaoying Dong, Bing Xiao

Pages: 386-398 Published online on: 02 May 2019

Annexin A2 regulates glioma cell proliferation through the STAT3‑cyclin D1 pathway

Ling Chen, Ling Lin, Na Xian, Zhihong Zheng

Pages: 399-413 Published online on: 09 May 2019

miR‑21 inhibitor facilitates the anticancer activity of doxorubicin loaded nanometer in melanoma

Xiaoyong Wei, Xiaolong You, Jianlong Zhang, Cuncai Zhou

Pages: 414-424 Published online on: 22 May 2019

(‑)‑Epigallocatechin‑3‑gallate inhibits bladder cancer stem cells via suppression of sonic hedgehog pathway

Xianchao Sun, Jin Song, Enlai Li, Hao Geng, Yuan Li, Dexin Yu, Caiyun Zhong

Pages: 425-435 Published online on: 24 May 2019

Resveratrol‑induced REG III expression enhances chemo‑ and radiosensitivity in head and neck cancer in xenograft mice

Shinji Mikami, Ichiro Ota, Takashi Masui, Tomoko Uchiyama, Hideyuki Okamoto, Takahiro Kimura, Shin Takasawa, Tadashi Kitahara

Pages: 436-442 Published online on: 25 April 2019

miR‑497 suppresses malignant phenotype in non‑small cell lung cancer via targeting KDR

Youyou Xia, Chenxi Hu, Lian Lian, Kaiyuan Hui, Lei Wang, Yun Qiao, Liang Liu, Lijun Liang, Xiaodong Jiang

Pages: 443-452 Published online on: 16 May 2019

ZNF492 and GPR149 methylation patterns as prognostic markers for clear cell renal cell carcinoma: Array‑based DNA methylation profiling

Yong‑June Kim, Wooyeong Jang, Xuan‑Mei Piao, Hyung‑Yoon Yoon, Young Joon Byun, Ji Sang Kim, Sung Min Kim, Sang Keun Lee, Sung Pil Seo, Ho Won Kang, Won Tae Kim, Seok Joong Yun, Ho Sun Shon, Keun Ho Ryu, Sang Won Kim, Yun‑Sok Ha, Ghil Suk Yoon, Sang‑Cheol Lee, Tae Gyun Kwon, Wun‑Jae Kim

Pages: 453-460 Published online on: 07 May 2019
Open Access

[Corrigendum] Metformin facilitates BG45‑induced apoptosis via an anti‑Warburg effect in cholangiocarcinoma cells

Dehua Tang, Lei Xu, Mingming Zhang, Robert Gregory Dorfman, Yida Pan, Qian Zhou, Lixing Zhou, Yuming Wang, Yang Li, Yuyao Yin, Lei Wang, Xiaoping Zou

Pages: 461-461 Published online on: 11 April 2019
Open Access

[Corrigendum] Increased expression of Lgr5 is associated with chemotherapy resistance in human gastric cancer

Hong‑Qing Xi, Jian‑Xin Cui, Wei‑Song Shen, Xiao‑Song Wu, Shi‑Bo Bian, Ji‑Yang Li, Zhou Song, Bo Wei, Lin Chen

Pages: 462-462 Published online on: 16 April 2019
Journal Cover

July-2019
Volume 42 Issue 1

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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