[Corrigendum] Exosomes derived from Piwil2‑induced cancer stem cells transform fibroblasts into cancer‑associated fibroblasts
Affiliations: Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children's Hospital of Chongqing Medical University, Chongqing Key Laboratory of Pediatrics, Chongqing 400014, P.R. China, Department of Urology, Children's Hospital of Chongqing Medical University, Chongqing 400014, P.R. China
- Published online on: January 27, 2022 https://doi.org/10.3892/or.2022.8273
- Article Number: 62
Copyright : © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
This article is mentioned in:
Oncol Rep 43: [Related article:] 1125-1132, 2020; DOI: 10.3892/or.2020.7496
Following the publication of the above paper, the authors have realized that they made an error during the assembly of the western blotting data in Fig. 4; essentially, the western blotting data shown for the FAP experiment in Fig. 5 were mistakenly inserted into Fig. 4 to show the metalloproteinase-9 (MMP-9) data.
MMP2 and MMP9 expression levels in FBs following incubation with Piwil2-iCSC-Exo (200 µg/ml). GAPDH was used as a loading control. At least three independent experiments were conducted. Results were considered statistically significant at P<0.05 (*P<0.05, **P<0.01 vs. control group; #P<0.05 vs. PBS group). One-way ANOVA and the LSD post hoc test were selected for analysis. FBs, fibroblasts; Piwil2-iCSC-Exo, exosomes derived from Piwil2-induced cancer stem cells; MMP, matrix metalloproteinase.
The authors re-examined their original data, and discovered how the error in the compilation of Fig. 4 arose. The corrected version of Fig. 4, incorporating the correct data for the MMP-9 experiment, is shown below. Note that this error did not affect the overall conclusions reported in the study. The authors are grateful to the Editor of Oncology Reports for allowing them the opportunity to publish this Corrigendum; furthermore, they apologize for any inconvenience caused to the readership of the Journal.