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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2026 Volume 55 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

ZBTB7A promotes malignant phenotypes in ovarian cancer through transcriptional activation of CRLF1

Xiaobai Hao, Yu Chen
Article Number: 102
Published online on: 24 March 2026

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Article Open Access

MS4322 is a selective protein arginine methyltransferase 5 degrader with antitumor effects in cervical cancer cells

Rui Luo, Jingping Chen, Zhaojie Chen, Surong Wang, Tianfeng Liu, Yang Xu
Article Number: 101
Published online on: 24 March 2026

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Retraction Open Access

[Retracted] Roles of the SNHG7/microRNA‑9‑5p/DPP4 ceRNA network in the growth and 131I resistance of thyroid carcinoma cells through PI3K/Akt activation

Wanzhi Chen, Jichun Yu, Rong Xie, Tao Zhou, Chengfeng Xiong, Shuyong Zhang, Meijun Zhong
Article Number: 100
Published online on: 23 March 2026

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Article Open Access

Andrographis exerts antitumor effects and enhances 5‑FU efficacy via the alteration of ferroptosis‑related genes in esophageal squamous cell carcinoma

Kosuke Yoshimura, Tadanobu Shimura, Ruiya Ma, Yaxuan Huang, Takahito Kitajima, Shinji Yamashita, Yuki Sato, Koki Higashi, Mikio Kawamura, Hiromi Yasuda, Yuhki Koike, Yoshiki Okita, Shigeyuki Yoshiyama, Minako Kobayashi, Masaki Ohi, Hiroki Ohge, Shinya Takahashi, Ajay Goel, Yoshinaga Okugawa, Yuji Toiyama
Article Number: 99
Published online on: 20 March 2026

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Article Open Access

Sphingosine‑1‑phosphate receptor 1 enhances olfactory receptor 51E1‑mediated inhibition of proliferation via Src/JNK signaling in prostate cancer cells

Kiheon Kim, Jinwoo Lee, Chulwon Choi, Jungnam Bae, Hee-Jung Choi, Won-Ki Huh
Article Number: 98
Published online on: 19 March 2026

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Review Open Access

Mechanistic insights into the roles of astragalosides and Astragalus polysaccharides in gynecological and breast cancers (Review)

Ruixin Liu, Zhanyu Lin, Yuelin Li, Yuetong Ci, Zhengqi Guo, Zhenguo Xu
Article Number: 97
Published online on: 19 March 2026

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Retraction Open Access

[Retracted] Inhibition of tankyrase 1 in human gastric cancer cells enhances telomere shortening by telomerase inhibitors 

Hao Zhang, Meng-Hua Yang, Jing-Jing Zhao, Ling Chen, Song-Tao Yu, Xu-Dong Tang, Dian-Chun Fang, Shi-Ming Yang
Article Number: 96
Published online on: 16 March 2026

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Article Open Access

Silencing of SIVA‑1 promotes cisplatin resistance in gastric cancer via the Bcl‑2/BAX‑mediated mitochondria‑dependent apoptosis pathway

Zheng-Yi Shi, Zheng-Rong Ding, Yu-Liang Huang, Yuan-Rui Lei, Hai-Bin Huang, Yan Qing, Miao-Ren Deng, Xu-Man Lu, Xu-Dong Dong, Long-Jie Xia, Sheng Xu, Xiao-Gang Zhong, Lei Li, Fan-Biao Kong, Xiao-Tong Wang
Article Number: 95
Published online on: 13 March 2026

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Article Open Access

Depleting HIF‑1α attenuates the progression of osteosarcoma, but tumorigenicity is sustained through HIF‑independent pathways

Ayaka Kunishima, Takatsune Shimizu, Tetsuya Takimoto, Atsunobu Sagara, Hiroyuki Nobusue, Hidetoshi Hasuwa, Shinya Hasegawa, Yuka Tamaoki, Hitomi Miyake, Yumi Fukuchi, Hideyuki Saya, Akihiro Muto
Article Number: 94
Published online on: 12 March 2026

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Article Open Access

Unveiling the role of ANGPT2 in esophageal cancer: A prognostic factor and potential oncogene

Zhigang Zhai, Zhenyu Xue, Yuan Fang, Yixu Fan, Shijiao Li, Yunpeng Yu, Chuansheng Chen, Kaijun Zhang, Deyu Chen, Xiang Tang, Rui Ling
Article Number: 93
Published online on: 12 March 2026

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Article Open Access

POLQ promotes tumor progression and immunosuppression via ATM‑P53 signaling in endometrial cancer

Ningning Zhu, Juanjuan Wang, Xiaoli Zhang, Kai Tang, Lei Gong, Yi Hu
Article Number: 92
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate and sodium citrate target glycolysis, suppress survivin, and induce mitochondrial‑mediated apoptosis in gastric cancer cells and inhibit gastric orthotopic transplantation tumor growth

Ting-An Wang, Xiao-Dong Zhang, Xing-Yu Guo, Shu-Lin Xian, Yun-Fei Lu
Article Number: 91
Published online on: 11 March 2026

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Review Open Access

Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review)

Zidong Xia, Huishan Zhai, Lei Zheng, Cheng Wang
Article Number: 90
Published online on: 09 March 2026

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Retraction Open Access

[Retracted] Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine‑γ‑lyase function

Liangyu Chen, Xinxing Li, Libo Liu, Bo Yu, Yixue Xue, Yunhui Liu
Article Number: 89
Published online on: 09 March 2026

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Review Open Access

Advances in the application of frailty scoring in the diagnosis and management of elderly patients with multiple myeloma (Review)

Junlun Liu, Danyu Li, Chao Li, Zhuoren Chen
Article Number: 88
Published online on: 06 March 2026

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Expression of Concern Open Access

[Expression of Concern] c‑Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma 

Lei You, Xiaoxia Ren, Yongxing Du, Wenjing Zhao, Ming Cui, Ge Chen, Yupei Zhao
Article Number: 87
Published online on: 05 March 2026

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Review Open Access

CXCL1 in triple‑negative breast cancer: Mechanisms, challenges, and therapeutic opportunities (Review)

Hiba Al Sayegh, Zahraa Assi, Amjad Kanaan, Mirvat El Sibai
Article Number: 86
Published online on: 03 March 2026

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Article Open Access

Cellular and inflammatory characteristics of patient‑derived glioblastoma organoids during in vitro cultivation

Jessica Nojszewski, Nils Oliver Schröder, Jacqueline Clüver, Jonna Holler, Hajrullah Ahmeti, Michael Synowitz, Janka Held-Feindt
Article Number: 85
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Growth and differentiation factor‑9 promotes adhesive and motile capacity of prostate cancer cells by up‑regulating FAK and Paxillin via Smad dependent pathway 

Sivan M. Bokobza, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Article Number: 84
Published online on: 02 March 2026

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Article Open Access

Platycodin D sensitizes head and neck squamous cell carcinoma to cisplatin by inducing autophagy arrest

Minji Bae, Min Kyeong Lee, Mi Gyeong Jeong, Yeonseo Lee, Harim Joo, Young Chan Lee, Jung Woo Lee, Su Il Kim, Seong-Gyu Ko, Young-Gyu Eun
Article Number: 83
Published online on: 27 February 2026

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Article Open Access

ACSBG1‑driven lipid reprogramming unveiled: A fatty acid metabolism‑associated prognostic model for lung adenocarcinoma

Panxin Hu, Anan Li
Article Number: 82
Published online on: 27 February 2026

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Article Open Access

Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation

Chao Li, Lei Yang, Yudong Zhang, Baocheng Zhao, Hao Qu
Article Number: 81
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways

Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang
Article Number: 80
Published online on: 25 February 2026

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Journal Cover
June-2026 Volume 55 Issue 6

Full Size Image

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Expression of Concern Open Access

[Expression of Concern] Metformin inhibits growth and sensitizes osteosarcoma cell lines to cisplatin through cell cycle modulation

Irene Quattrini, Amalia Conti, Laura Pazzaglia, Chiara Novello, Stefano Ferrari, Piero Picci, Maria Serena Benassi
Article Number: 111
Published online on: 08 April 2026

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Article Open Access

NF‑κB‑driven LUZP1 promotes metastasis and chemoresistance in head and neck squamous cell carcinoma

Chen-Yuan Lin, Ching-Yun Hsieh, Hsin-Chi Lan, Ching-Chan Lin, Tzu-Ting Chen, Wei-Chi Tseng, Yung-An Tsou, Wei-Chao Chang
Article Number: 110
Published online on: 07 April 2026

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Article Open Access

Hypoxic CAF studies unveil PTHrP‑vitamin D‑RAS axis as pivotal in the CAF

Shoichiro Nakajo, Mamoru Uemura, Hiroshi Kusafuka, Mao Osaki, Chikako Kusunoki, Nobuo Takiguchi, Mitsunobu Takeda, Yuki Sekido, Tsuyoshi Hata, Atsushi Hamabe, Takayuki Ogino, Norikatsu Miyoshi, Mitsuyoshi Tei, Yoshinori Kagawa, Hirofumi Yamamoto, Yuichiro Doki, Hidetoshi Eguchi
Article Number: 109
Published online on: 07 April 2026

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Retraction Open Access

[Retracted] miR‑24‑3p regulates bladder cancer cell proliferation, migration, invasion and autophagy by targeting DEDD

Guoqiang Yu, Zhaohui Jia, Zhongling Dou
Article Number: 108
Published online on: 06 April 2026

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Review Open Access

Role of CHD4 in tumor progression, DNA damage response and treatment resistance (Review)

Shuo Li, Quan Ma, Keying Lian, Zhisheng Jiang, Yun Ma
Article Number: 107
Published online on: 02 April 2026

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Review Open Access

T cell fate regulation in EBV‑associated nasopharyngeal carcinoma (Review)

Liuyang Zhang, Shun Ding, Dongzhui Chen, Benchi Cai, Zhonglin Mu
Article Number: 106
Published online on: 02 April 2026

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Retraction Open Access

[Retracted] Ultrasound‑targeted microbubble destruction‑mediated overexpression of Sirtuin 3 inhibits the progression of ovarian cancer

Li Cheng, Dongmei Zhang, Wei Yan
Article Number: 105
Published online on: 02 April 2026

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Review Open Access

HMGB3: A pivotal orchestrator of therapy resistance and cancer stemness in human malignancies (Review)

Ju Zhang, Yifan Sun, Lanyu Wang, Jiayu Gu, Ye Hua, Jianfeng Shao, Ninghan Feng
Article Number: 104
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] 5‑Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene

Xiaorong Wang, E. Chen, Xue Yang, Yin Wang, Zhen Quan, Xiaohou Wu, Chunli Luo
Article Number: 103
Published online on: 30 March 2026

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Article

Cytochalasin H isolated from mangrove‑derived endophytic fungus induces apoptosis and inhibits migration in lung cancer cells

Yuefan Ma, Xin Wu, Zihan Xiu, Xin Liu, Bingyu Huang, Liang Hu, Jiao Liu, Zhiyuan Zhou, Xudong Tang

Pages: 2899-2905
Published online on: 30 March 2018
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Article

Methylene blue-mediated photodynamic therapy enhances apoptosis in lung cancer cells

Eun Jin Lim, Chul-Ho Oak, Jeonghoon Heo, Young-Ho Kim

Pages: 856-862
Published online on: 24 May 2013
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Article

Optimization of antitumor treatment conditions for transcutaneous CO2 application: An in vivo study

Takeshi Ueha, Teruya Kawamoto, Yasuo Onishi, Risa Harada, Masaya Minoda, Mitsunori Toda, Hitomi Hara, Naomasa Fukase, Masahiro Kurosaka, Ryosuke Kuroda, Toshihiro Akisue, Yoshitada Sakai

Pages: 3688-3694
Published online on: 20 April 2017
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Article Open Access

Anticancer and apoptosis‑inducing effects of quercetin in vitro and in vivo

Mahmoud Hashemzaei, Amin Delarami Far, Arezoo Yari, Reza Entezari Heravi, Kaveh Tabrizian, Seyed Mohammad Taghdisi, Sarvenaz Ekhtiari Sadegh, Konstantinos Tsarouhas, Dimitrios Kouretas, George Tzanakakis, Dragana Nikitovic, Nikita Yurevich Anisimov, Demetrios   A. Spandidos, Aristides M. Tsatsakis, Ramin Rezaee

Pages: 819-828
Published online on: 28 June 2017
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Review

Non-coding RNAs as regulators in epigenetics (Review)

Jian-Wei Wei, Kai Huang, Chao Yang, Chun-Sheng Kang

Pages: 3-9
Published online on: 08 November 2016
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Article

SASS6 overexpression is associated with mitotic chromosomal abnormalities and a poor prognosis in patients with colorectal cancer

Kazuya Shinmura, Hisami Kato, Yuichi Kawanishi, Kiyoko Nagura, Takaharu Kamo, Yusuke Okubo, Yusuke Inoue, Nobuya Kurabe, Chunping Du, Moriya Iwaizumi, Kiyotaka Kurachi, Toshio Nakamura, Haruhiko Sugimura

Pages: 727-738
Published online on: 28 May 2015
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Article

Knockdown of SASS6 reduces growth of MDA‑MB‑231 triple‑negative breast cancer cells through arrest of the cell cycle at the G2/M phase

Lili Du, Jiexian Jing, Yan Wang, Xiaoqin Xu, Ting Sun, Yanchun Shi, Weigang Wang, Baoguo Tian, Cunzhi Han, Xianwen Zhao, Huibo Chang

Article Number: 101
Published online on: 13 April 2021
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Article

Anti-CD3 x EGFR bispecific antibody redirects cytokine-induced killer cells to glioblastoma in vitro and in vivo

Pan Ma, Qiang He, Wei Li, Xianliang Li, Huamin Han, Mengmeng Jin, Changzhen Liu, Hua Tao, Juan Ma, Bin Gao

Pages: 2567-2575
Published online on: 28 August 2015
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Article

Doxycycline targets aldehyde dehydrogenase‑positive breast cancer stem cells

Chang‑Ching Lin, Miao‑Chia Lo, Rebecca R. Moody, Nicholas O. Stevers, Samantha L. Tinsley, Duxin Sun

Pages: 3041-3047
Published online on: 27 March 2018
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Article

Establishment and characterization of a human cholangiocarcinoma cell line

Stephanie Ma, Liang Hu, Xiao-Hui Huang, Liang-Qi Cao, Kwok Wah Chan, Qian Wang, Xin-Yuan Guan

Pages: 1195-1200
Published online on: 01 November 2007
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Article

Upregulation of NEK2 is associated with drug resistance in ovarian cancer

Xia Liu, Yutao Gao, Yi Lu, Jian Zhang, Li Li, Fuqiang Yin

Pages: 745-754
Published online on: 09 December 2013
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Article

Prognostic value of MGMT promoter methylation in glioblastoma patients treated with temozolomide-based chemoradiation: A Portuguese multicentre study

Bruno M. Costa, Cláudia Caeiro, Inês Guimarães, Olga Martinho, Teresa Jaraquemada, Isabel Augusto, Lígia Castro, Lígia Osório, Paulo Linhares, Mrinalini Honavar, Mário Resende, Fátima Braga, Ana Silva, Fernando Pardal, Júlia Amorim, Rui Nabiço, Rui Almeida, Carlos Alegria, Manuel Pires, Célia Pinheiro, Ernesto Carvalho, José M. Lopes, Paulo Costa, Margarida Damasceno, Rui M. Reis

Pages: 1655-1662
Published online on: 01 June 2010
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Article

Prevalence and association of human papillomavirus 16, Epstein-Barr virus, herpes simplex virus-1 and cytomegalovirus infection with human esophageal carcinoma: A case-control study

Dong-Hong Zhang, Qing-Ying Zhang, Chao-Qun Hong, Jiong-Yu Chen, Zhong-Ying Shen, Yi Zhu

Pages: 1731-1738
Published online on: 23 March 2011
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The underlying molecular mechanism and potential drugs for treatment in papillary renal cell carcinoma: A study based on TCGA and Cmap datasets

Jin‑Shu Pang, Zhe‑Kun Li, Peng Lin, Xiao‑Dong Wang, Gang Chen, Hai‑Biao Yan, Sheng‑Hua Li

Pages: 2089-2102
Published online on: 14 February 2019
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Article

The role of serum response factor in hepatocellular carcinoma: An association with matrix metalloproteinase

Kyung Ryoul Kim, Jun Sang Bae, Ha Na Choi, Ho Sung Park, Kyu Yun Jang, Myoung Ja Chung, Woo Sung Moon

Pages: 1567-1572
Published online on: 12 August 2011
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Review Open Access

Progress in antitumor mechanisms and applications of phenformin (Review)

Qi Zhong, Duo Li, Xiao-Ping Yang

Article Number: 151
Published online on: 13 September 2024
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Review Open Access

Comprehensive <em>in‑silico</em> molecular analysis of early‑onset gastric cancer identifies novel genes implicated in disease characterization and progression (Review)

Fernán Gómez‑Valenzuela, Ian Silva, Ignacio N. Retamal, Benjamín García‑Bloj, Tomás De Mayo Glasser, Matías Muñoz‑Medel, Alex Gómez, Cristopher San Martín, Carolina Sánchez, Felipe Pinto, Paola Aravena, Andrea C. Sabioncello, Marcelo Garrido Villanueva, Fernando Sigler Chávez, Ignacio Corvalán, Henry Barrios, José M. Erpel, Patricio A. Manque, Juan A. Godoy, Marcelo Garrido

Article Number: 98
Published online on: 17 June 2025
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Article Open Access

Periostin, a matrix protein, has potential as a novel serodiagnostic marker for cholangiocarcinoma

Kiminori Fujimoto, Takumi Kawaguchi, Osamu Nakashima, Junya Ono, Shoichiro Ohta, Atsushi Kawaguchi, Tatsuyuki Tonan, Koichi Ohshima, Hirohisa Yano, Naofumi Hayabuchi, Kenji Izuhara, Michio Sata

Pages: 1211-1216
Published online on: 23 February 2011
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Article

Periostin, a matrix specific protein, is associated with proliferation and invasion of pancreatic cancer

Qi-Wen Ben, Xiao-Long Jin, Jun Liu, Xia Cai, Fei Yuan, Yao-Zong Yuan

Pages: 709-716
Published online on: 11 January 2011
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Article

Lenvatinib exhibits antineoplastic activity in anaplastic thyroid cancer in vitro and in vivo

Silvia Martina Ferrari, Guido Bocci, Teresa Di Desidero, Giusy Elia, Ilaria Ruffilli, Francesca Ragusa, Paola Orlandi, Sabrina Rosaria Paparo, Armando Patrizio, Simona Piaggi, Concettina La Motta, Salvatore Ulisse, Enke Baldini, Gabriele Materazzi, Paolo Miccoli, Alessandro Antonelli, Poupak Fallahi

Pages: 2225-2234
Published online on: 08 March 2018
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