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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2010 Volume 23 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Molecular markers guide diagnosis and treatment in Philadelphia chromosome-negative myeloproliferative disorders (Review)

Ana Maria Vladareanu, Carsten Müller-Tidow, Horia Bumbea, Sinziana Radesi
Pages: 595-604
Published online on: 01 March 2010

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Article Open Access

In vitro modulation of MMP-2 and MMP-9 in human cervical and ovarian cancer cell lines by cytokines, inducers and inhibitors

M. W. Roomi, J. C. Monterrey, T. Kalinovsky, M. Rath, A. Niedzwiecki
Pages: 605-614
Published online on: 01 March 2010

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Article Open Access

Mast cell tryptase promotes breast cancer migration and invasion

Meng Xiang, Yiping Gu, Fengdi Zhao, Hong Lu, Sifeng Chen, Lianhua Yin
Pages: 615-619
Published online on: 01 March 2010

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Article

The Akt expression correlates with the VEGF-A and -C expression as well as the microvessel and lymphatic vessel density in breast cancer

Shinichi Tsutsui, Ayumi Matsuyama, Manabu Yamamoto, Hideya Takeuchi, Yumi Oshiro, Teruyoshi Ishida, Yoshihiko Maehara
Pages: 621-630
Published online on: 01 March 2010

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Article

The expression of hDlg as a biomarker of the outcome in malignant fibrous histiocytomas

Rui Niimi, Akihiko Matsumine, Takahiro Iino, Tetsuya Murata, Ken Shintani, Shigeto Nakazora, Tomoki Nakamura, Yudai Uehara, Katsuyuki Kusuzaki, Tetsu Akiyama, Atsumasa Uchida
Pages: 631-638
Published online on: 01 March 2010

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Article

Overexpression of EGFR pathway-related genes in the circulation is highly correlated with EGFR mutations and overexpression in paired cancer tissue from patients with non-small cell lung cancer

Chung-Chi Chen, Hua-Hsien Chiu, Li-Chen Yen, Hui-Jen Chang, Ming-Sung Chang, Jong-Rung Tsai, Yi-Fang Chen, Shiu-Ru Lin
Pages: 639-645
Published online on: 01 March 2010

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Article

Phytoestrogens regulate the expression of genes involved in different biological processes in BRCA2 knocked down MCF-7, MDA-MB-231 and MCF-10a cell lines

Dominique J. Bernard-Gallon, Samir Satih, Nassera Chalabi, Nadege Rabiau, Remy Bosviel, Luc Fontana, Yves-Jean Bignon
Pages: 647-653
Published online on: 01 March 2010

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Article

Actin reorganization in CHO AA8 cells undergoing mitotic catastrophe and apoptosis induced by doxorubicin

D. Grzanka, A. Grzanka, M. Izdebska, L. Gackowska, A. Stepien, A. Marszalek
Pages: 655-663
Published online on: 01 March 2010

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Article

Curcumin blocks migration and invasion of mouse-rat hybrid retina ganglion cells (N18) through the inhibition of MMP-2, -9, FAK, Rho A and Rock-1 gene expression

Hui-Ju Lin, Chin-Cheng Su, Hsu-Feng Lu, Jai-Sing Yang, Shu-Chun Hsu, Siu-Wan Ip, Jia-Jiuan Wu, Yu-Ching Li, Chin-Chin Ho, Chih-Chung Wu, Jing-Gung Chung
Pages: 665-670
Published online on: 01 March 2010

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Article

Expression of Stat3 and Notch1 is associated with cisplatin resistance in head and neck squamous cell carcinoma

Feng Gu, Yongjie Ma, Zuping Zhang, Jinghui Zhao, Hisayuki Kobayashi, Lun Zhang, Li Fu
Pages: 671-676
Published online on: 01 March 2010

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Article

The knock-down of overexpressed EZH2 and BMI-1 does not prevent osteosarcoma growth

Hiromi Sasaki, Takao Setoguchi, Yukihiro Matsunoshita, Hui Gao, Masataka Hirotsu, Setsuro Komiya
Pages: 677-684
Published online on: 01 March 2010

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Article

In vivo functional differences in microvascular response of 4T1 and Caki-1 tumors after treatment with OXi4503

Mamta Wankhede, Casey DeDeugd, Dietmar W. Siemann, Brian S. Sorg
Pages: 685-692
Published online on: 01 March 2010

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Article

Cimetidine induces apoptosis in gastric cancer cells in vitro and inhibits tumor growth in vivo

Cheng-Gang Jiang, Fu-Rong Liu, Miao Yu, Jia-Bin Li, Hui-Mian Xu
Pages: 693-700
Published online on: 01 March 2010

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Article

Recapitulating orthotopic tumor model through establishment of a parotid gland tumor with lung metastasis using HeLa cell injection into nude mice

Young-Wook Park, Seong-Gon Kim, Je-Yong Choi, Suk Keun Lee
Pages: 701-708
Published online on: 01 March 2010

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Article

4-Chlorobenzoyl berbamine induces apoptosis and G2/M cell cycle arrest through the PI3K/Akt and NF-κB signal pathway in lymphoma cells

Hua-Ping Du, Jia-Kun Shen, Min Yang, Yun-Qui Wang, Xiang-Qui Yuan, Qiu-Ling Ma, Jie Jin
Pages: 709-716
Published online on: 01 March 2010

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Article

Enhanced antitumor efficiency of docetaxel-loaded nanoparticles in a human ovarian xenograft model with lower systemic toxicities by intratumoral delivery

Donghui Zheng, Dake Li, Xiaowei Lu, Zhenqing Feng
Pages: 717-724
Published online on: 01 March 2010

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Article

Constitutive NF-κB activity regulates the expression of VEGF and IL-8 and tumor angiogenesis of human glioblastoma

Tong-Xin Xie, Zhibo Xia, Nu Zhang, Weida Gong, Suyun Huang
Pages: 725-732
Published online on: 01 March 2010

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Article

Preparation of a novel adenovirus formulation with artificial envelope of multilayer polymer-coatings: Therapeutic effect on metastatic ovarian cancer

Chieko Yoshihara, Katsuyuki Hamada, Yoshiyuki Koyama
Pages: 733-738
Published online on: 01 March 2010

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Article

FGFR4 polymorphism, TP53 mutation, and their combinations are prognostic factors for oral squamous cell carcinoma

Jun-Ichi Tanuma, Toshiyuki Izumo, Masato Hirano, Yoshitaka Oyazato, Fumiya Hori, Eri Umemura, Hayase Shisa, Hiroshi Hiai, Motoo Kitano
Pages: 739-744
Published online on: 01 March 2010

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Article

Detection and genotyping of human papillomavirus in gynaecologic outpatients of Messina, eastern Sicily, Italy

Giuseppe Giuffrè, Angela Simone, Paolo Todaro, Maria Le Donne, Carmela Caruso, Alfonsa Pizzo, Domenico Granese
Pages: 745-750
Published online on: 01 March 2010

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Article

Differential apoptotic response in HPV-infected cancer cells of the uterine cervix after doxorubicin treatment

Dong Soo Suh, Seung Chul Kim, Won Geun An, Chang Hun Lee, Kyung Un Choi, Jin Mi Song, Jin Seup Jung, Kyu Sup Lee, Man Soo Yoon
Pages: 751-756
Published online on: 01 March 2010

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Article

Adhesion of ST6Gal I-mediated human colon cancer cells to fibronectin contributes to cell survival by integrin β1-mediated paxillin and AKT activation

Minyoung Lee, Jung-Jin Park, Yun-Sil Lee
Pages: 757-761
Published online on: 01 March 2010

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Article

Multiplex genotyping of 1107 SNPs from 232 candidate genes identified an association between IL1A polymorphism and breast cancer risk

Wonshik Han, So Young Kang, Daehee Kang, Sue K. Park, Ji-Young Lee, Ho Kim, Ae Kyung Park, Dong-Young Noh
Pages: 763-769
Published online on: 01 March 2010

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Article

Evaluation of 5-fluorouracil related genes in breast cancer to predict the effect of adjuvant therapy with oral fluorouracil derivatives

Yuko Tsunoda, Kenya Suzuki, Akira Tsunoda, Masafumi Takimoto, Mitsuo Kusano
Pages: 771-777
Published online on: 01 March 2010

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Article

Loss of mitochondrial DNA enhances angiogenic and invasive potential of hepatoma cells

Hwanju Cheon, Hyo-Eun Moon, Myung-Shik Lee, Soung Soo Kim
Pages: 779-786
Published online on: 01 March 2010

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Article

Effect of phytic acid and inositol on the proliferation and apoptosis of cells derived from colorectal carcinoma

L. Schröterová, P. Hasková, E. Rudolf, M. Cervinka
Pages: 787-793
Published online on: 01 March 2010

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Article

Expression of Efp, VEGF and bFGF in normal, hyperplastic and malignant endometrial tissue

Hongying Dai, Shuping Zhao, Lin Xu, Aiping Chen, Shuzhen Dai
Pages: 795-799
Published online on: 01 March 2010

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Article

KBH-A42, a histone deacetylase inhibitor, inhibits the growth of doxorubicin-resistant leukemia cells expressing P-glycoprotein

Moo Rim Kang, Kiho Lee, Jong Soon Kang, Chang Woo Lee, Ki Hoon Lee, Jang Hyun Kim, Jeong Wook Yang, Bo Geun Kim, Gyoonhee Han, Song-Kyu Park, Hwan Mook Kim
Pages: 801-809
Published online on: 01 March 2010

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Article

CAG repeats in the androgen receptor gene are shorter in patients with pulmonary, esophageal or bladder carcinoma and longer in women with uterine leiomyoma

Xiao-Ying Teng, Gui-Qiu Liu, Xiao-Li Diao, Zong-Yong Wu, Lan Li, Wei Zhang, Xun Zhang, Qin Su
Pages: 811-818
Published online on: 01 March 2010

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Article

Expression pattern and clinical significance of DNA methyltransferase 3B variants in gastric carcinoma

Xianwei Su, Chengyu Lv, Fengchang Qiao, Xuemei Qiu, Wenbin Huang, Qingxiang Wu, Zhujiang Zhao, Hong Fan
Pages: 819-826
Published online on: 01 March 2010

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Article

Characterization of a stem-like population in hepatocellular carcinoma MHCC97 cells

Ning Zhang, Ren Li, Kai-Shan Tao, Da-Yong Cao, Zhen-Yu Ti, Rui Ding, Lei Cai, Fu-Qin Zhang, Ke-Feng Dou
Pages: 827-831
Published online on: 01 March 2010

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Article

Lewis(y) antigen stimulates the growth of ovarian cancer cells via regulation of the epidermal growth factor receptor pathway

Juan-Juan Liu, Bei Lin, Ying-Ying Hao, Fei-Fei Li, Da-Wo Liu, Yue Qi, Lian-Cheng Zhu, Shu-Lan Zhang, Masao Iwamori
Pages: 833-841
Published online on: 01 March 2010

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Article

Aberrant expressions of HOX genes in colorectal and hepatocellular carcinomas

Motoshi Kanai, Jun-Ichi Hamada, Minoru Takada, Toshimichi Asano, Katsuhiko Murakawa, Yoko Takahashi, Taichi Murai, Mitsuhiro Tada, Masaki Miyamoto, Satoshi Kondo, Tetsuya Moriuchi
Pages: 843-851
Published online on: 01 March 2010

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Article

Simultaneous confidence intervals to compare gene expression profiles using ABC transporter TaqMan microfluidic cards

Sara Pizzamiglio, Giacomo Cossa, Laura Gatti, Giovanni L. Beretta, Elisabetta Corna, Stella Tinelli, Paolo Verderio, Paola Perego
Pages: 853-860
Published online on: 01 March 2010

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Article

Pharmacological inhibition of Rho-kinase signaling with Y-27632 blocks melanoma tumor growth

Alissa Routhier, Michelle Astuccio, Deanna Lahey, Nicholas Monfredo, Alyssa Johnson, William Callahan, Amy Partington, Kelly Fellows, Lori Ouellette, Sofiela Zhidro, Carrie Goodrow, Alexis Smith, Kaitlyn Sullivan, Peter Simone, Leo Le, Bora Vezuli, Micheline Zohni, Elizabeth West, Daniel Gleason, Brad Bryan
Pages: 861-867
Published online on: 01 March 2010

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Article

Src induces expression of carbonic anhydrase IX via hypoxia-inducible factor 1

Martina Takacova, Tereza Holotnakova, Monika Barathova, Silvia Pastorekova, Juraj Kopacek, Jaromir Pastorek
Pages: 869-874
Published online on: 01 March 2010

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Article

Role of the proteasome in the downregulation of transcription factors NFκB and C/EBP in macrophages from tumor hosts

Giselle Perry, Viyaya Iragavarapu-Charyulu, Edward W. Harhaj, Marta Torroella-Kouri
Pages: 875-881
Published online on: 01 March 2010

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Journal Cover
November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Targeting the DNHD1‑HDAC6 axis inactivates prostate cancer cell aggressiveness in vitro, suggesting potential therapeutic vulnerability

An Ni Lee, Chia Chang Wu, Su Wei Hu, Chih Heng Chen, Yi Te Chiang, Wei Tang Kao, Kai Yi Tzou, Chia Hung Liu, Shao Wei Dong, Yu Ting Wang, Yueh Lin Lee, Siou Bi Li, Che An Wu, Chiao Chun Liao, Ming Hsien Chan, Po Han Chiu, Chien Hsiu Li
Article Number: 198
Published online on: 30 September 2026

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Article Open Access

Loperamide enhances the radiosensitivity of cervical cancer cells via ferroptosis induction

Huarong Guo, Haixia Li, Shunkang Tian, Yunkai Zhang, Fuyun Wu, Jing Ke
Article Number: 197
Published online on: 30 September 2026

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Review Open Access

Mitochondrial mechanisms underlying spatial immune phenotypes in non‑small cell lung cancer: Implications for ICI response and cold‑to‑hot tumor conversion (Review)

Hongyi Lai, Ke Sun, Tong Mu, Xi Liu, Mingshan Liu
Article Number: 196
Published online on: 30 September 2026

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Article Open Access

PINK1 promotes the progression of lung squamous cell carcinoma through the FAK/AKT/RhoA/vinculin pathway

Xu Li, Yuhui Ma
Article Number: 195
Published online on: 29 September 2026

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Expression of Concern Open Access

[Expression of Concern] MicroRNA‑195‑5p is a potential diagnostic and therapeutic target for breast cancer

Qifeng Luo, Chuankui Wei, Xiaoyu Li, Jia Li, Lei Chen, Yixiang Huang, Hongming Song, Dengfeng Li, Lin Fang
Article Number: 194
Published online on: 23 September 2026

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Article Open Access

SGPP1 as a tumor suppressor in esophageal squamous cell carcinoma: Potential molecular mechanisms involving UGT1A9/UGT2B28 and clinical prognostic significance

Linlin Su, Liubing Hou, Xuetao Han, Ge Zhang, Jiayuan Li, Yu Wang, Yuxin Han, Xiaoying Xue, Huandi Zhou
Article Number: 193
Published online on: 23 September 2026

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Correction Open Access

[Corrigendum] High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer

Yahua Chen, Jun Liu, Wei Wang, Li Xiang, Jide Wang, Side Liu, Hongyan Zhou, Zheng Guo
Article Number: 192
Published online on: 21 September 2026

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Review Open Access

Overcoming melanoma drug resistance: Mechanisms and clinical progress of oncolytic viruses combined with immune checkpoint inhibitors (Review)

Yuan He, Wenxuan Lin, Haofang Chen, Yongqi Guan, Congcong Guan, Yanxiang Zhang, Dongsheng Pan
Article Number: 191
Published online on: 17 September 2026

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Article Open Access

Validation of next‑generation sequencing‑derived circulating mRNA variants as potential diagnostic tools in hepatocellular carcinoma and cholangiocarcinoma

Daniel Zezulinski, Maarouf A. Hoteit, David E. Kaplan, Tingting Zhan, Cataldo Doria, Timothy M. Block, Aejaz Sayeed
Article Number: 190
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer

Le Hong, Gen Sun, Long Peng, Yi Tu, Zhen Wan, Haiwei Xiong, Yong Li, Weidong Xiao
Article Number: 189
Published online on: 16 September 2026

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Article Open Access

Pemetrexed increases BRCA1 protein stability and sensitizes TNBC cells to radiotherapy

Hee Jin, Kyung-Hwa Jeon, Chaerin Kang, Joohyun Lee, Yeonjin Lee, Youngjoo Kwon, Yun-Sil Lee
Article Number: 188
Published online on: 15 September 2026

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Article Open Access

FXYD5 promotes the growth of glioblastoma by targeting the PI3K/AKT/ACSL4 signaling axis

Bang Wang, Yong Qin, Hang Cheng, Yibin Zeng, Lianglei Jiang, Xuebin Hu
Article Number: 187
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] RIP kinase‑mediated ROS production triggers XAF1 expression through activation of TAp73 in casticin‑treated bladder cancer cells

Yoon Hee Chung, Daejin Kim
Article Number: 186
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo activities of an antitumor peptide HM‑3: A special dose‑efficacy relationship on an HCT‑116 xenograft model in nude mice

Sitelbanat Yassin, Jialiang Hu, Hanmei Xu, Ce Li, Sarra Setrerrahmane
Article Number: 185
Published online on: 10 September 2026

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Article Open Access

Effect of EZH2 regulation of the JAK2/STAT3 signaling pathway on proliferation and apoptosis in non‑small cell lung cancer cells

Shuang Wu, Wei Zhang
Article Number: 184
Published online on: 08 September 2026

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Correction Open Access

[Corrigendum] TGF‑β1 mediates epithelial to mesenchymal transition via the TGF‑β/Smad pathway in squamous cell carcinoma of the head and neck

Changyun Yu, Yong Liu, Donghai Huang, Yaozhang Dai, Gengming Cai, Jinjie Sun, Ting Xu, Yongquan Tian, Xin Zhang
Article Number: 183
Published online on: 31 August 2026

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Journal Cover
December-2026 Volume 56 Issue 6

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in resistance mechanisms and counterstrategies for antibody‑drug conjugates in HER2‑low and HER2‑ultralow breast cancer (Review)

Xiaojie Yu, Meilin Ren, Longdi Yao
Article Number: 208
Published online on: 20 October 2026

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Article Open Access

CHCHD2 as a prognostic biomarker and therapeutic target in lung adenocarcinoma: Insights from pan‑cancer multi‑omics and functional studies

Zikai Xu, Jie Shen, Yizhou Lin, Haotian Shi, Cong Zhang, Zhengwei Zhang, Xiaoyu Zhou, Zheng Yang
Article Number: 207
Published online on: 15 October 2026

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Article Open Access

PBRM1 knockdown is associated with NRF2‑dependent ALDOA upregulation and metabolic reprogramming in HCCC‑9810 intrahepatic cholangiocarcinoma cells

Dong Zhang, Dezheng Liu, Shukuan Yang, Zijian Zhao, Xuekai Zhao, Yongshuo Liu, Fan Zhang, Lei Zhou
Article Number: 206
Published online on: 15 October 2026

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Article Open Access

SEC31A promotes gastric cancer progression by inducing the PI3K/AKT/mTOR pathway and enhancing the CCL5‑mediated M2 polarization and recruitment of tumor‑associated macrophages

Xixian Zhao, Liuye Huang
Article Number: 205
Published online on: 14 October 2026

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Review

Advances in neoadjuvant therapy for locally advanced head and neck squamous cell carcinoma (Review)

Hong You, Xinghu Qin, Shaozhi Fu
Article Number: 204
Published online on: 14 October 2026

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Review Open Access

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Review Open Access

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Retraction Open Access

[Retracted] miR‑29a inhibits human retinoblastoma progression by targeting STAT3

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Article Number: 201
Published online on: 08 October 2026

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Article Open Access

Expression of V‑domain Ig suppressor of T cell activation in ovarian cancer and its regulation of follicular regulatory T‑cell function via the AKT/MAPK pathway

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Expression of Concern Open Access

[Expression of Concern] ZNF703 promotes tumor cell proliferation and invasion and predicts poor prognosis in patients with colorectal cancer

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Published online on: 30 September 2026

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