Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 1021-335X Online ISSN: 1791-2431
Journal Cover
August-2014 Volume 32 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
August-2014 Volume 32 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Review

Clinical evidence of the relationship between aspirin and breast cancer risk (Review)

  • Authors:
    • Nadia J. Jacobo-Herrera
    • Carlos Pérez-Plasencia
    • Elizabeth  Camacho‑Zavala
    • Gabriela Figueroa González
    • Eduardo López Urrutia
    • Verónica  García‑Castillo
    • Alejandro Zentella-Dehesa
  • View Affiliations / Copyright

    Affiliations: Unidad de Bioquímica, Instituto Nacional de Ciencias Médicas y Nutrición ‘Salvador Zubirán’, Tlalpan 14000, Mexico, D.F., Mexico , Unidad de Biomedicina FES-Iztacala, Universidad Nacional Autónoma de México UNAM, Tlalnepantla 54090, Mexico, Laboratorio de Oncogenómica, Instituto Nacional de Cancerología, Tlalpan 14080, Mexico, D.F., Mexico
  • Pages: 451-451
    |
    Published online on: June 13, 2014
       https://doi.org/10.3892/or.2014.3270
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

In the search for new therapeutic alternatives against cancer, either as a preventive treatment or for advanced stages, it is common to appeal to well-known drugs used for the treatment of other diseases that may interfere with the metabolic pathways involved in carcinogenesis. Non-steroidal anti-inflammatory drugs (NSAIDs) display anticancer activity through the inhibition of the COX-2 enzyme, triggering processes such as apoptosis, a reduction in proliferation and inhibition of carcinogenesis. Breast cancer is a neoplasm with the highest incidence and mortality rate among young women worldwide. Epidemiologic data have shown that drugs such as NSAIDs, particularly aspirin, reduce the relative risk of breast cancer. However, in the subgroup of responsive patients, dose, time and frequency of use have not yet been established. Here, we review the reports published during the last 10 years regarding the relationship between breast cancer and aspirin.
View Figures

Figure 1

View References

1 

Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM: Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 127:2893–2917. 2010. View Article : Google Scholar : PubMed/NCBI

2 

Chávarri-Guerra Y, Villarreal-Garza C, Liedke PE, et al: Breast cancer in Mexico: a growing challenge to health and the health system. Lancet Oncol. 13:e335–e343. 2012.PubMed/NCBI

3 

Rodríguez-Cuevas SA and Capurso-García M: Epidemiology of breast cancer. Ginecol Obstet Mex. 74:585–593. 2006.(In Spanish).

4 

Zentella-Dehesa A, Frías S, Galicia-Vázquez G, et al: Cáncer de glándula mamaria y metástasis: un creciente problema de salud pública en México. Mensaje Bioquímico. Oria Hernández J, Rendón Huerta E, Reyes Vivas H, Romero Álvarez I and Velázquez López I: Mexico: UNAM; XXXI. pp. 172–195. 2007

5 

Spallarossa P, Altieri P, Aloi C, et al: Doxorubicin induces senescence or apoptosis in rat neonatal cardiomyocytes by regulating the expression levels of the telomere binding factors 1 and 2. Am J Physiol Heart Circ Physiol. 297:H2169–H2181. 2009. View Article : Google Scholar : PubMed/NCBI

6 

Elliott P: Pathogenesis of cardiotoxicity induced by anthracyclines. Semin Oncol. 33:S2–S7. 2006. View Article : Google Scholar : PubMed/NCBI

7 

Rice J: Metastasis: The rude awakening. Nature. 485:S55–S57. 2012. View Article : Google Scholar : PubMed/NCBI

8 

Khuder SA and Mutgi AB: Breast cancer and NSAID use: a meta-analysis. Br J Cancer. 84:1188–1192. 2001. View Article : Google Scholar : PubMed/NCBI

9 

Agrawal A and Fentiman IS: NSAIDs and breast cancer: a possible prevention and treatment strategy. Int J Clin Pract. 62:444–449. 2008. View Article : Google Scholar : PubMed/NCBI

10 

Johnson TW, Anderson KE, Lazovich D and Folsom AR: Association of aspirin and nonsteroidal anti-inflammatory drugs use with breast cancer. Cancer Epidemiol Biomarkers Prev. 11:1586–1592. 2002.PubMed/NCBI

11 

Harris RE, Chlebowski RT, Jackson RD, et al: Breast cancer and nonsteroidal anti-inflammatory drugs: prospective results from the Women’s Health Initiative. Cancer Res. 63:6096–6101. 2003.

12 

Ratnasinghe LD, Graubard BI, Kahle L, Tangrea JA, Taylor PR and Hawk E: Aspirin use and mortality from cancer in a prospective cohort study. Anticancer Res. 24:3177–3184. 2004.PubMed/NCBI

13 

Marshall SF, Bernstein L, Anton-Culver H, et al: Nonsteroidal anti-inflammatory drugs use and breast cancer risk by stage and hormone receptor status. J Natl Cancer Inst. 97:805–812. 2005. View Article : Google Scholar : PubMed/NCBI

14 

Egan KM, Stampfer MJ, Giovannucci E, Rosner BA and Colditz GA: Prospective study of regular aspirin use and the risk of breast cancer. J Natl Cancer Inst. 88:988–993. 1996. View Article : Google Scholar : PubMed/NCBI

15 

Kirsh VA, Kreiger N, Cotterchio M, Sloan M and Theis B: Nonsteroidal anti-inflammatory drug use and breast cancer risk: subgroup findings. Am J Epidemiol. 166:709–716. 2007. View Article : Google Scholar : PubMed/NCBI

16 

Terry MB, Gammon MD, Zhang FF, et al: Association of frequency and duration of aspirin use and hormone receptor status with breast cancer risk. JAMA. 291:2433–2440. 2004. View Article : Google Scholar : PubMed/NCBI

17 

Zhang Y, Coogan PF, Palmer JR, Strom BL and Rosenberg L: Use of nonsteroidal anti-inflammatory drugs and risk of breast cancer: the case-control surveillance study revisited. Am J Epidemiol. 162:165–170. 2005. View Article : Google Scholar : PubMed/NCBI

18 

Friis S, Sørensen HT, McLaughlin JK, Johnsen SP, Blot WJ and Olsen JH: A population-based cohort study of the risk of colorectal and other cancers among users of low-dose aspirin. Br J Cancer. 88:684–688. 2003. View Article : Google Scholar : PubMed/NCBI

19 

Friis S, Thomassen L, Sørensen HT, et al: Nonsteroidal anti-inflammatory drug use and breast cancer risk: a Danish cohort study. Eur J Cancer Prev. 17:88–96. 2008. View Article : Google Scholar : PubMed/NCBI

20 

Cook NR, Lee IM, Gaziano JM, et al: Low-dose aspirin in the primary prevention of cancer. The Women’s Health Study: a randomized controlled trial. JAMA. 294:47–55. 2005.

21 

Jacobs EJ, Thun MJ, Connell CJ, et al: Aspirin and other nonsteroidal anti-inflammatory drugs and breast cancer incidence in a large U.S. cohort. Cancer Epidem Biomarkers Prev. 14:261–264. 2005.PubMed/NCBI

22 

Jacobs EJ, Thun MJ, Bain EB, Rodriguez C, Henley SJ and Calle EE: A large cohort study of long-term daily use of adult strength aspirin and cancer incidence. J Nat Cancer Inst. 99:608–615. 2007. View Article : Google Scholar : PubMed/NCBI

23 

Schreinemachers DM and Everson RB: Aspirin use and lung, colon, and breast cancer incidence in a prospective study. Epidemiology. 5:138–146. 1994. View Article : Google Scholar : PubMed/NCBI

24 

Bardia A, Ebbert JO, Vierkant RB, et al: Association of aspirin and non-aspirin non-steroidal anti-inflammatory drugs with cancer incidence and mortality. J Natl Cancer Inst. 99:881–889. 2007. View Article : Google Scholar : PubMed/NCBI

25 

Badawi AF, Habib SL, Mohammed MA, Abadi AA and Michael MS: Influence of cigarette smoking on prostaglandin synthesis and cyclooxygenase-2 gene expression in human urinary bladder cancer. Cancer Invest. 20:651–656. 2002. View Article : Google Scholar : PubMed/NCBI

26 

Martey CA, Pollock SJ, Turner CK, et al: Cigarette smoke induces cyclooxygenase-2 and microsomal prostaglandin E2 synthase in human lung fibroblast: implications for lung inflammation and cancer. Am J Physiol Lung Cell Mol Physiol. 287:L981–L991. 2004. View Article : Google Scholar : PubMed/NCBI

27 

Ready A, Velicer CM, McTiernan A and White E: NSAID use and breast cancer risk in the VITAL cohort. Breast Cancer Res Treat. 109:533–543. 2008. View Article : Google Scholar : PubMed/NCBI

28 

Gill JK, Maskarinec G, Wilkens LR, Pike MC, Henderson BE and Kolonel LN: Nonsteroidal anti-inflammatory drugs and breast cancer risk: the multiethnic cohort. Am J Epidemol. 166:1150–1158. 2007. View Article : Google Scholar : PubMed/NCBI

29 

Langman MJS, Cheng KK, Gilman EA and Lancashire RJ: Effect of anti-inflammatory drugs overall risk of common cancer: case-control study in general practice research database. BMJ. 320:1642–1646. 2000. View Article : Google Scholar : PubMed/NCBI

30 

Moorman PG, Grubber JM, Millikan RC and Newman B: Association between nonsteroidal anti-inflammatory drugs (NSAIDs) and invasive breast cancer and carcinoma in situ of the breast. Cancer Causes Control. 14:915–922. 2003. View Article : Google Scholar : PubMed/NCBI

31 

Cotterchio M, Kreiger N, Sloan M and Steingart A: Nonsteroidal anti-inflammatory drug used and breast cancer risk. Cancer Epidemiol Biormarkers Prev. 10:1213–1217. 2001.PubMed/NCBI

32 

García Rodríguez LA and González Pérez A: Risk of breast cancer among users of aspirin and other anti-inflammatory drugs. Br J Cancer. 91:525–529. 2004.PubMed/NCBI

33 

Swede H, Mirand AL, Menezes RJ and Moysich KB: Association of regular aspirin use and breast cancer risk. Oncology. 68:40–47. 2005. View Article : Google Scholar : PubMed/NCBI

34 

Slattery ML, Curtin K, Baumgartner R, et al: IL6, aspirin, nonsteroidal anti-inflammatory drugs, and breast cancer risk in women living in the southwestern United States. Cancer Epidemiol Biomarkers Prev. 16:747–755. 2007. View Article : Google Scholar : PubMed/NCBI

35 

Hojo T, Akiyama Y, Nagasaki K, et al: Association of maspin expression with the malignancy grade and tumor vascularization in breast cancer tissues. Cancer Lett. 171:103–110. 2001. View Article : Google Scholar : PubMed/NCBI

36 

Maass N, Hojo T, Rosel F, Ikeda T, Jonat W and Nagasaki K: Down regulation of the tumor suppressor gene maspin in breast carcinoma is associated with a higher risk of distant metastasis. Clin Biochem. 34:303–307. 2001. View Article : Google Scholar : PubMed/NCBI

37 

Girish GV, Sinha N, Chakraborty K, Bhattacharya G, Kahn NN and Sinha AK: Restoration by aspirin of impaired plasma maspin level in human breast cancer. Acta Oncol. 45:184–187. 2006. View Article : Google Scholar : PubMed/NCBI

38 

Bhattacharyya M, Girish GV, Ghosh R, Chakraborty S and Sinha AK: Acetylsalicylic acid (aspirin) improves synthesis of maspin and lowers incidence of metastasis in breast cancer patients. Cancer Sci. 101:2105–2109. 2010. View Article : Google Scholar : PubMed/NCBI

39 

Rothwell PM, Wilson M, Price JF, Belch JF, Meade TW and Mehta Z: Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials. Lancet. 379:1592–1601. 2012.PubMed/NCBI

40 

Bambace NM and Holmes CE: The platelet contribution to cancer progression. J Thromb Haemostat. 9:237–249. 2011. View Article : Google Scholar : PubMed/NCBI

41 

Joyce JA and Pollard JW: Microenvironmental regulation of metastasis. Nature Rev Cancer. 9:239–252. 2009. View Article : Google Scholar : PubMed/NCBI

42 

Gay LJ and Felding-Habermann B: Contribution of platelets to tumour metastasis. Nature Rev Cancer. 11:123–134. 2011. View Article : Google Scholar : PubMed/NCBI

43 

Holmes MD, Chen WY, Li L, Hetzmark E, Spiegelman D and Hankinson SE: Aspirin intake and survival after breast cancer. J Clin Oncol. 28:1467–1472. 2010. View Article : Google Scholar : PubMed/NCBI

44 

Smith WL, DeWitt DL and Garavito RM: Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem. 69:145–182. 2000. View Article : Google Scholar : PubMed/NCBI

45 

Zha S, Yegnasubramanian V, Nelson WG, Isaacs WB and De Marzo AM: Cyclooxygenases in cancer: progress and perspective. Cancer Lett. 215:1–20. 2004. View Article : Google Scholar : PubMed/NCBI

46 

Giercksky KE: COX-2 inhibition and prevention of cancer. Best Pract Res Clin Gastroenterol. 15:821–833. 2001. View Article : Google Scholar : PubMed/NCBI

47 

Ulrich CM, Bigler J and Potter JD: Non-steroidal anti-inflammatory drugs for cancer prevention: promise, perils and pharmacogenetics. Nature Review Cancer. 6:130–140. 2006. View Article : Google Scholar : PubMed/NCBI

48 

Moran EM: Epidemiological and clinical aspects of nonsteroidal anti-inflammatory drugs and cancer risk. J Environ Pathol Toxicol Oncol. 21:193–202. 2002. View Article : Google Scholar : PubMed/NCBI

49 

Vane JR and Botting RM: Mechanism of action of aspirin-like drugs. Semin Arthritis Rheum. 26:2–10. 1997. View Article : Google Scholar : PubMed/NCBI

50 

Buttar NS and Wang KK: The “aspirin” of the new millenium: cyclooxigenase-2 inhibitors. Mayo Clin Proc. 75:1027–1038. 2000.

51 

Elwood PC, Gallagher AM, Duthie GG, Mur LA and Morgan G: Aspirin, salicylates, and cancer. Lancet. 373:1301–1309. 2009. View Article : Google Scholar : PubMed/NCBI

52 

Langley RE, Burdett S, Tierney JF, Cafferty F, Parmar MK and Venning G: Aspirin and cancer: has aspirin been overlooked as an adjuvant therapy? Br J Cancer. 105:1107–1113. 2011. View Article : Google Scholar : PubMed/NCBI

53 

Meric JB, Rottey S, Olaussen K, Soria JC, Khayat D, Rixe O and Spano JP: Cyclooygenase-2 as a target for anticancer drug development. Crit Rev Oncol Hematol. 59:51–64. 2006. View Article : Google Scholar : PubMed/NCBI

54 

Hwang D, Scollard D, Byrne J and Levine E: Expression of cyclooxygenase-1 and cyclooxygenase-2 in human breast cancer. J Natl Cancer Inst. 90:455–460. 1998. View Article : Google Scholar : PubMed/NCBI

55 

He TC, Chan TA, Volgestein B and Kinzlet KW: PPAR delta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell. 99:335–345. 1999. View Article : Google Scholar : PubMed/NCBI

56 

Davies G, Martin LA, Sacks N and Dowsett M: Cyclooxygenase-2 (COX-2), aromatase and breast cancer: a possible role for COX-2 inhibitors in breast cancer chemoprevention. Ann Oncol. 13:669–678. 2002. View Article : Google Scholar : PubMed/NCBI

57 

Subbaramaiah K, Chung WJ and Dannenberg AJ: Ceramide regulates the transcription of cyclooxygenase-2. Evidence for involvement of extracellular signal-regulated kinase/c-Jun N-terminal kinase and p38 mitogen-activated protein kinase pathways. J Biol Chem. 273:32943–32949. 1998. View Article : Google Scholar

58 

Brueggemeier RW, Quinn AL, Parrett ML, Joarder FS, Harris RE and Robertson FM: Correlation of aromatase and cyclooxygenase gene expression in human breast cancer specimens. Cancer Lett. 140:27–35. 1999. View Article : Google Scholar : PubMed/NCBI

59 

Goss PE, Ingle JN, Martino S, et al: A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early breast cancer. N Engl J Med. 349:1793–1802. 2003.PubMed/NCBI

60 

Mazhar E, Ang R and Waxman J: COX inhibitors and breast cancer. Br J Cancer. 94:346–350. 2006. View Article : Google Scholar

61 

Bosetti C, Gallus S and La Vecchia C: Aspirin and cancer risk: an updated quantitative review to 2005. Cancer Causes Control. 17:871–888. 2006. View Article : Google Scholar : PubMed/NCBI

62 

Crew KD and Neugut AI: Aspirin and NSAIDs: effects in breast and ovarian cancers. Curr Opin Obstet Gynecol. 18:71–75. 2006. View Article : Google Scholar : PubMed/NCBI

63 

Fosslien E: Molecular pathology of cyclooxygenase-2 in neoplasia. Ann Clin Lab Sci. 30:3–21. 2000.PubMed/NCBI

64 

Bosetti C, Gallus S and La Vecchia C: Aspirin and cancer risk: an update to 2001. Eur J Cancer Prev. 11:535–542. 2002. View Article : Google Scholar : PubMed/NCBI

65 

Howe LR, Subbaramaiah K, Brown AMC and Dannenberg AJ: Cyclooxygenase-2: a target for the prevention and treatment of breast cancer. Endocr Relat Cancer. 8:97–114. 2001. View Article : Google Scholar : PubMed/NCBI

66 

Ratnasinghe D, Daschner PJ, Anver MR, et al: Cyclooxygenase-2 P-glycoprotein-170 and drug resistance; is chemoprevention against multidrug resistance possible? Anticancer Res. 21:2141–2147. 2001.PubMed/NCBI

67 

Streuli CH: Maspin is a tumour suppressor that inhibits breast cancer tumour metastasis in vivo. Breast Cancer Res. 4:137–140. 2002. View Article : Google Scholar : PubMed/NCBI

68 

Solomon LA, Munkarah AR, Schimp VL, et al: Maspin expression and localization impact on angiogenesis and prognosis in ovarian cancer. Gynecol Oncol. 101:385–389. 2006. View Article : Google Scholar : PubMed/NCBI

69 

Burnett GT, Weathersby DC, Taylor TE and Bremner TA: Regulation of inflammation and angiogenesis-related gene expression in breast cancer cells and co-cultured macrophages. Anticancer Res. 28:2093–2099. 2008.PubMed/NCBI

70 

Spitz GA, Furtado CM, Sola-Penna M and Zancan P: Acetylsalicylic acid and salicylic acid decrease tumor cell viability and glucose metabolism modulating 6-phosphofructo-1-kinase structure and activity. Biochem Pharmacol. 77:46–53. 2009. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Jacobo-Herrera NJ, Pérez-Plasencia C, Camacho‑Zavala E, González GF, Urrutia EL, García‑Castillo V and Zentella-Dehesa A: Clinical evidence of the relationship between aspirin and breast cancer risk (Review). Oncol Rep 32: 451-451, 2014.
APA
Jacobo-Herrera, N.J., Pérez-Plasencia, C., Camacho‑Zavala, E., González, G.F., Urrutia, E.L., García‑Castillo, V., & Zentella-Dehesa, A. (2014). Clinical evidence of the relationship between aspirin and breast cancer risk (Review). Oncology Reports, 32, 451-451. https://doi.org/10.3892/or.2014.3270
MLA
Jacobo-Herrera, N. J., Pérez-Plasencia, C., Camacho‑Zavala, E., González, G. F., Urrutia, E. L., García‑Castillo, V., Zentella-Dehesa, A."Clinical evidence of the relationship between aspirin and breast cancer risk (Review)". Oncology Reports 32.2 (2014): 451-451.
Chicago
Jacobo-Herrera, N. J., Pérez-Plasencia, C., Camacho‑Zavala, E., González, G. F., Urrutia, E. L., García‑Castillo, V., Zentella-Dehesa, A."Clinical evidence of the relationship between aspirin and breast cancer risk (Review)". Oncology Reports 32, no. 2 (2014): 451-451. https://doi.org/10.3892/or.2014.3270
Copy and paste a formatted citation
x
Spandidos Publications style
Jacobo-Herrera NJ, Pérez-Plasencia C, Camacho‑Zavala E, González GF, Urrutia EL, García‑Castillo V and Zentella-Dehesa A: Clinical evidence of the relationship between aspirin and breast cancer risk (Review). Oncol Rep 32: 451-451, 2014.
APA
Jacobo-Herrera, N.J., Pérez-Plasencia, C., Camacho‑Zavala, E., González, G.F., Urrutia, E.L., García‑Castillo, V., & Zentella-Dehesa, A. (2014). Clinical evidence of the relationship between aspirin and breast cancer risk (Review). Oncology Reports, 32, 451-451. https://doi.org/10.3892/or.2014.3270
MLA
Jacobo-Herrera, N. J., Pérez-Plasencia, C., Camacho‑Zavala, E., González, G. F., Urrutia, E. L., García‑Castillo, V., Zentella-Dehesa, A."Clinical evidence of the relationship between aspirin and breast cancer risk (Review)". Oncology Reports 32.2 (2014): 451-451.
Chicago
Jacobo-Herrera, N. J., Pérez-Plasencia, C., Camacho‑Zavala, E., González, G. F., Urrutia, E. L., García‑Castillo, V., Zentella-Dehesa, A."Clinical evidence of the relationship between aspirin and breast cancer risk (Review)". Oncology Reports 32, no. 2 (2014): 451-451. https://doi.org/10.3892/or.2014.3270
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team