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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2009 Volume 34 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Overexpression of eukaryotic elongation factor eEF2 in gastrointestinal cancers and its involvement in G2/M progression in the cell cycle

Junya Nakamura, Sayaka Aoyagi, Isamu Nanchi, Shin-Ichi Nakatsuka, Erika Hirata, Shohei Shibata, Mari Fukuda, Yumiko Yamamoto, Ikuyo Fukuda, Naoya Tatsumi, Tazu Ueda, Fumihiro Fujiki, Masaya Nomura, Sumiyuki Nishida, Toshiaki Shirakata, Naoki Hosen, Akihoro Tsuboi, Yoshihiro Oka, Riichiro Nezu, Masaki Mori, Yuichiro Doki, Katsuyuki Aozasa, Haruo Sugiyama, Yusuke Oji
Pages: 1181-1189
Published online on: 01 May 2009

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Article

Human keratinocytes derived from the bulge region of hair follicles are refractory to differentiation

Yusuke Sasahara, Yoshie Yoshikawa, Tomonori Morinaga, Yoshiro Nakano, Nozomi Kanazawa, Joji Kotani, Shin Kawamata, Yoshinobu Murakami, Katsuyuki Takeuchi, Chizuko Inoue, Yukio Kitano, Tomoko Hashimoto-Tamaoki
Pages: 1191-1199
Published online on: 01 May 2009

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Article

Tumor initiating potential of side population cells in human gastric cancer

Kazumasa Fukuda, Yoshiro Saikawa, Masaki Ohashi, Koshi Kumagai, Masaki Kitajima, Hideyuki Okano, Yumi Matsuzaki, Yuko Kitagawa
Pages: 1201-1207
Published online on: 01 May 2009

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Article

Stat3-siRNA induces Fas-mediated apoptosis in vitro and in vivo in breast cancer

Sateesh Kunigal, Sajani S. Lakka, Prasanna Kumar Sodadasu, Norman Estes, Jasti S. Rao
Pages: 1209-1220
Published online on: 01 May 2009

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Article

Berberine inhibits p53-dependent cell growth through induction of apoptosis of prostate cancer cells

Myoung Suk Choi, Ju Hoon Oh, Sun Mi Kim, Hai Young Jung, Hwan Soo Yoo, Yong Moon Lee, Dong Cheul Moon, Sang Bae Han, Jin Tae Hong
Pages: 1221-1230
Published online on: 01 May 2009

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Article Open Access

Adenovirus-mediated eukaryotic initiation factor 4E binding protein-1 in combination with rapamycin inhibits tumor growth of pancreatic ductal adenocarcinoma in vivo

Roshan Mishra, Masaki Miyamoto, Tatsuya Yoshioka, Keidai Ishikawa, Yoshiyuki Matsumura, Yasuhito Shoji, Kazuomi Ichinokawa, Tommo Itoh, Toshiaki Shichinohe, Satoshi Hirano, Satoshi Kondo
Pages: 1231-1240
Published online on: 01 May 2009

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Article

Gene silencing of translationally controlled tumor protein (TCTP) by siRNA inhibits cell growth and induces apoptosis of human prostate cancer cells

Munirathinam Gnanasekar, Sivasakthivel Thirugnanam, Guoxing Zheng, Aoshuang Chen, Kalyanasundaram Ramaswamy
Pages: 1241-1246
Published online on: 01 May 2009

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Article

Human precision-cut liver tumor slices as a tumor patient-individual predictive test system for oncolytic measles vaccine viruses

Martina Zimmermann, Sorin Armeanu, Irina Smirnow, Susan Kupka, Silvia Wagner, Manfred Wehrmann, Marianne G. Rots, Geny M.M. Groothuis, Thomas S. Weiss, Alfred Königsrainer, Michael Gregor, Michael Bitzer, Ulrich M. Lauer
Pages: 1247-1256
Published online on: 01 May 2009

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Article

Immunohistochemical determination of the appropriate anti-hTERT antibodies for in situ detection of telomerase activity in frozen sections of head and neck squamous cell carcinomas and tumor margin tissues

Eva-Maria Fabricius, Ute Kruse-Boitschenko, Reem Khoury, Gustav-Paul Wildner, Jan-Dirk Raguse, Martin Klein
Pages: 1257-1279
Published online on: 01 May 2009

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Article

Identification of proteins associated to multi-drug resistance in LoVo human colon cancer cells

Michele Visentin, Maria Paola Simula, Franca Sartor, Alessandra Petrucco, Valli De Re, Giuseppe Toffoli
Pages: 1281-1289
Published online on: 01 May 2009

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Article

Tyrosine phosphorylation of PP2A is regulated by HER-2 signalling and correlates with breast cancer progression

Lee Lee Wong, Chan Fong Chang, Evelyn S.C. Koay, Daohai Zhang
Pages: 1291-1301
Published online on: 01 May 2009

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Article

P-glycoprotein expression affects 18F-fluorodeoxyglucose accumulation in hepatocellular carcinoma in vivo and in vitro

Satoru Seo, Etsuro Hatano, Tatsuya Higashi, Akio Nakajima, Yuji Nakamoto, Masaharu Tada, Nobuyuki Tamaki, Keiko Iwaisako, Koji Kitamura, Iwao Ikai, Shinji Uemoto
Pages: 1303-1312
Published online on: 01 May 2009

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Article

A novel germline mutation of hMLH1 in a Korean hereditary non-polyposis colorectal cancer family

Ki-Hwan Kim, Ju-Young Kim, Se-Ig Oh, Haing-Woon Baik, Dong-Wook Kang, Sung-Hee Jung, Jeong-Hoon Rho, In-Taek Hwang
Pages: 1313-1318
Published online on: 01 May 2009

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Article

Curcumin blocks CCL2-induced adhesion, motility and invasion, in part, through down-regulation of CCL2 expression and proteolytic activity

Jeffery G. Herman, Henry L. Stadelman, Charles E. Roselli
Pages: 1319-1327
Published online on: 01 May 2009

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Article

Bone marrow CFU-GM and human tumor xenograft efficacy of three antitumor nucleoside analogs

Rebecca G. Bagley, Stephanie Roth, Leslie S. Kurtzberg, Cecile Rouleau, Min Yao, Jennifer Crawford, Roy Krumbholz, Dennis Lovett, Steven Schmid, Beverly A. Teicher
Pages: 1329-1340
Published online on: 01 May 2009

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Article Open Access

AMT: Preclinical pharmacology studies

Faiz Niazi, Joachim Drevs, Klaus Diergarten, Annette Dorn, Armin Maier, Heinz Herbert Fiebig, Eddy Bruyns, Jürgen Scheele
Pages: 1341-1352
Published online on: 01 May 2009

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Article

Efficacy on anaplastic thyroid carcinoma of valproic acid alone or in combination with doxorubicin, a synthetic chenodeoxycholic acid derivative, or lactacystin

Tae Hyun Kim, Young Hyun Yoo, Do-Young Kang, Hongsuk Suh, Moon Ki Park, Ki-Jae Park, Sung-Heun Kim
Pages: 1353-1362
Published online on: 01 May 2009

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Article

Down-regulation of hTERT expression plays an important role in 15-deoxy-Δ12,14-prostaglandin J2-induced apoptosis in cancer cells

Mikako Moriai, Naoki Tsuji, Daisuke Kobayashi, Kageaki Kuribayashi, Naoki Watanabe
Pages: 1363-1372
Published online on: 01 May 2009

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Article

1-(3-C-Ethynyl-β-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), a novel potent inhibitor of RNA polymerase, potentiates the cytotoxicity of CDDP in human cancer cells both in vitro and in vivo

Hiromi Kazuno, Akio Fujioka, Masakazu Fukushima, Yusuke Wataya, Akira Matsuda, Takuma Sasaki
Pages: 1373-1380
Published online on: 01 May 2009

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Article

Sphere-forming stem-like cell populations with drug resistance in human sarcoma cell lines

Hiromasa Fujii, Kanya Honoki, Toshifumi Tsujiuchi, Akira Kido, Kazuhiro Yoshitani, Yoshinori Takakura
Pages: 1381-1386
Published online on: 01 May 2009

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Article

Immunogenic properties of renal cell carcinoma and the pathogenesis of osteolytic bone metastases

Francesca Perut, Elisabetta Cenni, Ronald E. Unger, C. James Kirkpatrick, Armando Giunti, Nicola Baldini
Pages: 1387-1393
Published online on: 01 May 2009

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Article Open Access

The MDM2 antagonist nutlin-3 sensitizes p53-null neuroblastoma cells to doxorubicin via E2F1 and TAp73

Susan K. Peirce, Harry W. Findley
Pages: 1395-1402
Published online on: 01 May 2009

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Article

Down-regulation of myopodin expression reduces invasion and motility of PC-3 prostate cancer cells

Ariane De Ganck, Veerle De Corte, Erik Bruyneel, Marc Bracke, Joel Vandekerckhove, Jan Gettemans
Pages: 1403-1409
Published online on: 01 May 2009

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Article

Transcriptional regulation of WNT2B based on the balance of Hedgehog, Notch, BMP and WNT signals

Masuko Katoh, Masaru Katoh
Pages: 1411-1415
Published online on: 01 May 2009

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Article

Transcription factor YY1 expression in human gastrointestinal cancer cells

Dharmaraj Chinnappan, Dongmei Xiao, Anita Ratnasari, Chris Andry, Thomas C. King, H. Christian Weber
Pages: 1417-1423
Published online on: 01 May 2009

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Article

High Cks1 expression in transgenic and carcinogen-initiated mammary tumors is not always accompanied by reduction in p27Kip1

Louise Westbrook, Harish N. Ramanathan, Tatyana Isayeva, Anshu Roy Mittal, Zhican Qu, Michael D. Johnson, Francis G. Kern, Selvarangan Ponnazhagan, Clinton J. Grubbs, Jaideep V. Thottassery
Pages: 1425-1431
Published online on: 01 May 2009

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Article

Three-dimensional culture using a radial flow bioreactor induces matrix metalloprotease 7-mediated EMT-like process in tumor cells via TGFβ1/Smad pathway

Shun-Ichi Shibata, Hideki Marushima, Tadashi Asakura, Tomokazu Matsuura, Homare Eda, Katsuhiko Aoki, Hiroshi Matsudaira, Kazu Ueda, Kiyoshi Ohkawa
Pages: 1433-1448
Published online on: 01 May 2009

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Article

Tumor initiating cancer stem cells from human breast cancer cell lines

Ji Seung Han, David L. Crowe
Pages: 1449-1453
Published online on: 01 May 2009

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Article

Se-methylselenocysteine sensitized TRAIL-mediated apoptosis via down-regulation of Bcl-2 expression

Jung Tae Lee, Tae-Jin Lee, Jong-Wook Park, Taeg Kyu Kwon
Pages: 1455-1460
Published online on: 01 May 2009

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Article

miR-145 inhibits breast cancer cell growth through RTKN

Shihua Wang, Chunjing Bian, Zhuo Yang, Ye Bo, Jing Li, Lifen Zeng, Hong Zhou, Robert Chunhua Zhao
Pages: 1461-1466
Published online on: 01 May 2009

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Article

Nimesulide, a selective COX-2 inhibitor, acts synergistically with ionizing radiation against A549 human lung cancer cells through the activation of caspase-8 and caspase-3

Byeong Mo Kim, Juyoon Won, Kyung Ah Maeng, Young Soo Han, Yeon-Sook Yun, Sung Hee Hong
Pages: 1467-1473
Published online on: 01 May 2009

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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