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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2004 Volume 11 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Clinicopathological significance of sialyl Lex expression in human gallbladder carcinoma

Hiroyuki Kashiwagi, Hiroshi Kijima, Shoichi Dowaki, Yasuo Ohtani, Kosuke Tobita, Hitoshi Yamazaki, Masato Nakamura, Yoshito Ueyama, Makiko Tanaka, Sadaki Inokuchi, Toshihide Imaizumi, Hiroyasu Makuuchi
Pages: 1139-1143
Published online on: 01 June 2004

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Article

Experimental study on the toxicity and the local and systemic tolerability of gemcitabine after topical treatment of the rabbit bladder

M. Matera, G. Costantino, G. Clementi, L. Lempereur, D. Vasta, E. Vasquez
Pages: 1145-1151
Published online on: 01 June 2004

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Article

Human kallikrein 8 (hK8/TADG-14) expression is associated with an early clinical stage and favorable prognosis in ovarian cancer

Kazushi Shigemasa, Xiurong Tian, Lijun Gu, Hirotoshi Tanimoto, Lowell J. Underwood, Timothy J. O'Brien, Koso Ohama
Pages: 1153-1159
Published online on: 01 June 2004

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Article

Comparison between triple therapy with octreotide, galanin and serotonin, 5-fluorouracil/leucovorin, and sequential treatment with both, on human colon cancer

Magdy El-Salhy
Pages: 1161-1168
Published online on: 01 June 2004

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Article

Establishment and characterization of a renal cell carcinoma cell line (FU-UR-1) with the reciprocal ASPL-TFE3 fusion transcript

Masako Ishiguro, Hiroshi Iwasaki, Yuko Ohjimi, Yasuhiko Kaneko
Pages: 1169-1175
Published online on: 01 June 2004

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Article

Effects of triple therapy with octreotide, galanin and serotonin on liver metastasis of human colon cancer in xenografts

Magdy El-Salhy, Veronica Dennerqvist
Pages: 1177-1182
Published online on: 01 June 2004

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Article

Fas and Fas ligand: Expression and soluble circulating levels in bile duct carcinoma

Masateru Murakami, Tamito Sasaki, Hideki Miyata, Souichirou Yamasaki, Kenichi Kuwahara, Kazuaki Chayama
Pages: 1183-1186
Published online on: 01 June 2004

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Article

Regulation of matrix metalloproteinase 13 expression by androgen in prostate cancer

See-Tong Pang, Amilcar Flores-Morales, Lambert Skoog, Yin-Choy Chuan, Gunnar Nordstedt, Åke Pousette
Pages: 1187-1192
Published online on: 01 June 2004

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Article

Prognostic significance of nm23 gene product expression in patients with colorectal carcinoma treated with radical intent

Paolo Soliani, Stefanie Ziegler, Antonello Romani, Luigi Corcione, Nicoletta Campanini, Paolo Dell'Abate, Paolo Del Rio, Mario Sianesi
Pages: 1193-1200
Published online on: 01 June 2004

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Article

Frequent translocalization of β-catenin in gastric cancers and its relevance to tumor progression

Xiao-Xin Cheng, Yuan Sun, Xiao-Yan Chen, Kai-Li Zhang, Qing-You Kong, Jia Liu, Hong Li
Pages: 1201-1207
Published online on: 01 June 2004

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Article

High mobility group A1 expression correlates with the histological grade of human glial tumors

Giuseppe Donato, Josefina Martinez Hoyos, Andrea Amorosi, Lorenza Maltese, Angelo Lavano, Giorgio Volpentesta, Francesco Signorelli, Francesca Pentimalli, Pierlorenzo Pallante, Giuseppe Ferraro, Luigi Tucci, Cosma Damiano Signorelli, Giuseppe Viglietto, Alfredo Fusco
Pages: 1209-1213
Published online on: 01 June 2004

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Article

Molecular cytogenetic characterisation of the colorectal cancer cell line SW480

Jordi Camps, Kristin Mrasek, Esther Prat, Anja Weise, Heike Starke, Josep Egozcue, Rosa Miró, Thomas Liehr
Pages: 1215-1218
Published online on: 01 June 2004

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Article

Effect of Nma on growth inhibition by TGF-βa in human gastric carcinoma cell lines

Takamitsu Sasaki, Tomonori Sasahira, Hideo Shimura, Seiyo Ikeda, Hiroki Kuniyasu
Pages: 1219-1223
Published online on: 01 June 2004

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Article

Investigating the relationship between serum thrombopoietin kinetics and the platelet-sparing effect: A clinical pharmacological evaluation of combined paclitaxel and carboplatin in patients with non-small cell lung cancer

Haruko Daga, Takeshi Isobe, Mitsuru Miyazaki, Kazunori Fujitaka, Keiichi Kondo, Nobuoki Kohno
Pages: 1225-1231
Published online on: 01 June 2004

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Article

Preoperative endoscopic analysis of thymidine phosphorylase and dihydropyrimidine dehydrogenase in gastrointestinal cancer

Tsukasa Hotta, Katsutoshi Taniguchi, Yasuhito Kobayashi, Kiyofumi Johata, Masaki Sahara, Teiji Naka, Takashi Watanabe, Minoru Ochiai, Hiroshi Tanimura, Yukari T. Tsubota
Pages: 1233-1239
Published online on: 01 June 2004

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Article

ω-6 polyunsaturated fatty acid γ-linolenic acid (18:3n-6) enhances docetaxel (Taxotere) cytotoxicity in human breast carcinoma cells: Relationship to lipid peroxidation and HER-2/neu expression

Javier Abel Menendez, Santiago Ropero, Ruth Lupu, Ramon Colomer
Pages: 1241-1252
Published online on: 01 June 2004

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Article

Antineoplastic action of 5-aza-2'-deoxycytidine (Dacogen) and depsipeptide on Raji lymphoma cells

Sepideh Shaker, Mark Bernstein, Richard L. Momparler
Pages: 1253-1256
Published online on: 01 June 2004

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Article

Differentially expressed genes in multidrug resistant variants of U-2 OS human osteosarcoma cells

Tokuhiro Chano, Kanji Mori, Katia Scotlandi, Stefania Benini, Cristina Lapucci, Maria Cristina Manara, Massimo Serra, Piero Picci, Hidetoshi Okabe, Nicola Baldini
Pages: 1257-1263
Published online on: 01 June 2004

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Article

Neoadjuvant chemotherapy for local advanced breast cancer with stage IIIB

Ryungsa Kim, Akihiko Osaki, Kazuaki Tanabe, Tetsuya Toge
Pages: 1265-1272
Published online on: 01 June 2004

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Article

Effect of type I growth factor receptor tyrosine kinase inhibitors on phosphorylation and transactivation activity of the androgen receptor in prostate cancer cells: Ligand-independent activation of the N-terminal domain of the androgen receptor

Shozo Sugita, Hidenori Kawashima, Tomoaki Tanaka, Takeshi Kurisu, Kazunobu Sugimura, Tatsuya Nakatani
Pages: 1273-1279
Published online on: 01 June 2004

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Spectrum of p53 mutations in biopsies from breast cancer patients selected for preoperative chemotherapy analysed by the functional yeast assay to predict therapeutic response

Helmut Deissler, Ariane Kafka, Eva Schuster, Georg Sauer, Rolf Kreienberg, Robert Zeillinger
Pages: 1281-1286
Published online on: 01 June 2004

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Article

S100A11 gene identified by in-house cDNA microarray as an accurate predictor of lymph node metastases of gastric cancer

Mikito Mori, Hideaki Shimada, Yoshio Gunji, Hisahiro Matsubara, Hideki Hayashi, Yoshinori Nimura, Masaki Kato, Masaki Takiguchi, Takenori Ochiai, Naohiko Seki
Pages: 1287-1293
Published online on: 01 June 2004

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Article

13-cis retinoic acid in head and neck cancer chemoprevention: results of a randomized trial from the Italian Head and Neck Chemoprevention Study Group

Salvatore Toma, Luigina Bonelli, Alberto Sartoris, Eugenio Mira, Antonio Antonelli, Fabio Beatrice, Carlo Giordano, Marco Benazzo, Angelo Caroggio, Andrea Luigi Cavalot, Sergio Gandolfo, Aldo Garozzo, Giovanni Margarino, Guido Schenone, Nicoletta Spadini, Zuzana Sirotovà, Francesco Zibordi, Fabrizio Balzarini, Italo Serafini, Piero Miani, Giorgio Cortesina
Pages: 1297-1305
Published online on: 01 June 2004

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Article

Analysis of telomerase activity and telomere length in bone and soft tissue tumors

Tadashi Terasaki, Satoru Kyo, Masahiro Takakura, Yoshiko Maida, Hiroyuki Tsuchiya, Katsuro Tomita, Masaki Inoue
Pages: 1307-1311
Published online on: 01 June 2004

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Article

Efficiency of lipofection combined with hyperthermia in Lewis lung carcinoma cells and a rodent pleural dissemination model of lung carcinoma

Atsushi Okita, Hiroyuki Mushiake, Kazunori Tsukuda, Motoi Aoe, Masakazu Murakami, Akio Andou, Nobuyoshi Shimizu
Pages: 1313-1318
Published online on: 01 June 2004

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Article

Differential PIAS3 expression in human malignancy

Liming Wang, Sipra Banerjee
Pages: 1319-1324
Published online on: 01 June 2004

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Case Report

The biological basis for the use of an anti-androgen and a 5-α-reductase inhibitor in the treatment of recurrentprostate cancer: Case report and review

Long G. Wang, Simon K. Mencher, J. P. McCarron, Anna C. Ferrari
Pages: 1325-1329
Published online on: 01 June 2004

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Article

The course of serum HER-2/neu levels as an independent prognostic factor for survival in metastatic breast cancer

Walter Schippinger, Peter Regitnig, Thomas Bauernhofer, Ferdinand Ploner, Günter Hofmann, Peter Krippl, Martin Wehrschütz, Sigurd Lax, Walter Carney, Rainer Neumann, Klaus-Dieter Wernecke, Hellmut Samonigg
Pages: 1331-1336
Published online on: 01 June 2004

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Article

Expression of TAP73 and ΔNP73 in malignant gliomas

Hasan Ugur, A. E. Sayan, Sukru O. Ozdamar, Yucel Kanpolat, Mehmet Ozturk
Pages: 1337-1341
Published online on: 01 June 2004

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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