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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2003 Volume 23 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Molecular regulators of angiogenesis in the developing nervous system and adult brain tumors (Review)

Gelareh Zadeh, Abhijit Guha
Pages: 557-565
Published online on: 01 September 2003

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Article

A commonly deleted region in ovarian cancer on chromosome 19p13.3, not including the OAZ1 gene

Nozomu Yanaihara, Aikou Okamoto, Senya Matsufuji
Pages: 567-575
Published online on: 01 September 2003

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Article

Abrogation of VEGF expression in human head and neck squamous cell carcinoma decreases angiogenic activity in vitro and in vivo

Frank Riedel, Karl Götte, Mengfeng Li, Karl Hörmann, Jennifer Rubin Grandis
Pages: 577-583
Published online on: 01 September 2003

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Article

N-glycosylation is required for the surface localization of MUC17 mucin

Jenny J.L. Ho, Reena S. Jaituni, Suzanne C. Crawley, Stacey C. Yang, James R. Gum, Young S. Kim
Pages: 585-592
Published online on: 01 September 2003

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Article

Angiotensin converting enzyme-independent, local angiotensin II-generation in human pancreatic ductal cancer tissues

Tetsuo Ohta, Kohji Amaya, Shuangqin Yi, Hirohisa Kitagawa, Masato Kayahara, Itasu Ninomiya, Sachio Fushida, Takashi Fujimura, Gen-Ichi Nishimura, Koichi Shimizu, Koichi Miwa
Pages: 593-598
Published online on: 01 September 2003

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Article

Mutational, epigenetic and expressional analyses of caveolin-1 gene in cervical cancers

Te-Fu Chan, Tsung-Hsien Su, Kun-Tu Yeh, Jan-Yi Chang, Ting-Hsu Lin, Jui-Chang Chen, Shyng-Shiou F. Yuang, Jan-Gowth Chang
Pages: 599-604
Published online on: 01 September 2003

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Article

Detection of circulating cancer cells in human oral squamous cell carcinoma

Hirofumi Zen, Koh-Ichi Nakashiro, Satoru Shintani, Tomoki Sumida, Takayoshi Aramoto, Hiroyuki Hamakawa
Pages: 605-610
Published online on: 01 September 2003

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Article

Augmentation of endothelial cell monolayer permeability by hyperthermia but not tumor necrosis factor: Evidence for disruption of vascular integrity via VE-cadherin down-regulation

Josef Friedl, Ewa Turner, H. Richard Alexander
Pages: 611-616
Published online on: 01 September 2003

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Article

Identification of signature genes by microarray for acute myeloid leukemia without maturation and acute promyelocytic leukemia with t(15;17)(q22;q12)(PML/RARα)

Jun Morikawa, Huai Li, Seungchan Kim, Kazuhiro Nishi, Satoshi Ueno, Edward Suh, Edward Dougherty, Ilya Shmulevich, Hiroshi Shiku, Wei Zhang, Tohru Kobayashi
Pages: 617-625
Published online on: 01 September 2003

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Article

Apoptosis induction of vitamin K2 in lung carcinoma cell lines: the possibility of vitamin K2 therapy for lung cancer

Tsuyoshi Yoshida, Keisuke Miyazawa, Ikuma Kasuga, Tomohisa Yokoyama, Kazushige Minemura, Kenta Ustumi, Masahiro Aoshima, Kazuma Ohyashiki
Pages: 627-632
Published online on: 01 September 2003

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Article

Protein kinase C isoform expression in ovarian carcinoma correlates with indicators of poor prognosis

Wilko Weichert, Volker Gekeler, Carsten Denkert, Manfred Dietel, Steffen Hauptmann
Pages: 633-639
Published online on: 01 September 2003

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Article

Prognostic relevance of MAPK expression in glioblastoma multiforme

Christian Mawrin, Sabine Diete, Tim Treuheit, Siegfried Kropf, Christian K. Vorwerk, Carsten Boltze, Elmar Kirches, Raimund Firsching, Knut Dietzmann
Pages: 641-648
Published online on: 01 September 2003

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Article

Effect of formalin fixation on the near-infrared Raman spectroscopy of normal and cancerous human bronchial tissues

Zhiwei Huang, Annette McWilliams, Stephen Lam, John English, David I. McLean, Harvey Lui, Haishan Zeng
Pages: 649-655
Published online on: 01 September 2003

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Article

Expression and function of activin receptors in human endometrial adenocarcinoma cells

Tetsuji Tanaka, Saori Toujima, Tsutomu Otani, Sawako Minami, Mareo Yamoto, Naohiko Umesaki
Pages: 657-663
Published online on: 01 September 2003

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Article

Apoptosis induction and enhancement of cytotoxicity of anticancer drugs by celecoxib, a selective cyclooxygenase-2 inhibitor, in human head and neck carcinoma cell lines

Susumu Hashitani, Masahiro Urade, Norihiko Nishimura, Tsunenari Maeda, Kazuki Takaoka, Kazuma Noguchi, Kazunari Sakurai
Pages: 665-672
Published online on: 01 September 2003

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Article

Two ways to induce innate immune responses in human PBMCs: Paracrine stimulation of IFN-α responses by viral protein or dsRNA

Philippe Fournier, Jinyang Zeng, Volker Schirrmacher
Pages: 673-680
Published online on: 01 September 2003

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Article

Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarray

Yasuyuki Kaneta, Yoshitoyo Kagami, Tatsuhiko Tsunoda, Ryuzo Ohno, Yusuke Nakamura, Toyomasa Katagiri
Pages: 681-691
Published online on: 01 September 2003

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Article

Aberrant methylation in promoter-associated CpG islands of multiple genes in therapy-related leukemia

Eisuke Uehara, Seisho Takeuchi, Taizo Tasaka, Yoshiko Matsuhashi, Yang Yang, Mitsuhiro Fujita, Takahiro Tamura, Masami Nagai, H. Phillip Koeffler
Pages: 693-696
Published online on: 01 September 2003

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Article

The pesticide malathion induces alterations in actin cytoskeleton and in cell adhesion of cultured breast carcinoma cells

G. Cabello, S. Galaz, L. Botella, G. Calaf, M. Pacheco, J. C. Stockert, A. Villanueva, M. Cañete, A. Juarranz
Pages: 697-704
Published online on: 01 September 2003

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Article

Anthocyanidins induce apoptosis in human promyelocytic leukemia cells: Structure-activity relationship and mechanisms involved

De-Xing Hou, Takashi Ose, Shigang Lin, Kazuhiro Harazoro, Izumi Imamura, Mayumi Kubo, Takuhiro Uto, Norihiko Terahara, Makoto Yoshimoto, Makoto Fujii
Pages: 705-712
Published online on: 01 September 2003

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Article

Anti-Fas antibody-induced apoptosis and its signal transduction in human gastric carcinoma cell lines

Keiko Adachi, Mitsuhiko Osaki, Satoru Kase, Ami Takeda, Hisao Ito
Pages: 713-719
Published online on: 01 September 2003

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Article

Inhibition of NF-κB pathway in grape seed extract-induced apoptotic death of human prostate carcinoma DU145 cells

Sivanandhan Dhanalakshmi, Rajesh Agarwal, Chapla Agarwal
Pages: 721-727
Published online on: 01 September 2003

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Article

Antiproliferative effect of chlorophyllin derived from a traditional Chinese medicine Bombyx mori excreta on human breast cancer MCF-7 cells

Lawrence Chi-Ming Chiu, Carrie K.-L. Kong, Vincent E.C. Ooi
Pages: 729-735
Published online on: 01 September 2003

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Article

Genomic structure and mutational analysis of the human KIF1Bα gene located at 1p36.2 in neuroblastoma

Yu Yan Chen, Junko Takita, Ying Zhang Chen, Hong Wei Yang, Ryoji Hanada, Keiko Yamamoto, Yasuhide Hayashi
Pages: 737-744
Published online on: 01 September 2003

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Article

A hypoxic response induced in MatLyLu cells by cobalt chloride results in an enhanced angiogenic response by the chick chorioallantoic membrane

T. Van Lieshout, J. Stanisz, V. Espiritu, M. Richardson, G. Singh
Pages: 745-750
Published online on: 01 September 2003

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Article

Overadditive anti-proliferative and pro-apoptotic effects of a combination therapy on colorectal carcinoma cells

Christoph Herold, M. Ganslmayer, M. Ocker, S. Blauberger, S. Zopf, E. G. Hahn, D. Schuppan
Pages: 751-756
Published online on: 01 September 2003

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Article

Role of cytokeratins, nuclear matrix proteins, Lewis antigen and epidermal growth factor receptor in human bladder tumors

Angelina Di Carlo, Daniela Terracciano, Angela Mariano, Andrea Oliva, Massimo D'Armiento, Vincenzo Macchia
Pages: 757-762
Published online on: 01 September 2003

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Article

IL-6 is a key factor in growth inhibition of human myeloma cells induced by pravastatin, an HMG-CoA reductase inhibitor

Takemi Otsuki, Haruko Sakaguchi, Masaaki Eto, Tomohiro Fujii, Tamayo Hatayama, Akiko Takata, Takayuki Tsujioka, Takashi Sugihara, Fuminori Hyodoh
Pages: 763-768
Published online on: 01 September 2003

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Article

Sialic acids linked to glycoconjugates of Fas regulate the caspase-9-dependent and mitochondria-mediated pathway of Fas-induced apoptosis in Jurkat T cell lymphoma

Osamu Suzuki, Yoshihiro Nozawa, Masafumi Abe
Pages: 769-774
Published online on: 01 September 2003

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Article

Immunization with live HPV-16-transformed mouse cells expressing the herpes simplex thymidine kinase and either GM-CSF or IL-2

Pavel Jinoch, Roman Zak, Olga Janousková, David Kunke, Simon Rittich, Martina Duskova, Eva Sobotkova, Iuri Marinov, Monika Andelova, Michal Smahel, Vladimir Vonka
Pages: 775-783
Published online on: 01 September 2003

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Article

Inhibition of pre-mRNA splicing by cisplatin and platinum analogs

Thomas D. Schmittgen, Jing-Fang Ju, Kathleen D. Danenberg, Peter V. Danenberg
Pages: 785-789
Published online on: 01 September 2003

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Article

Hepatic disseminated tumor cells in colorectal cancer UICC stage 4 patients: Prognostic implications

Christoph C. Schimanski, Ulrich Linnemann, Peter R. Galle, R. Arbogast, Martin R. Berger
Pages: 791-796
Published online on: 01 September 2003

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Article

17β-estradiol-induced activation of ERK1/2 through endogenous androgen receptor-estradiol receptor α-Src complex in human prostate cells

Paolo Chieffi, Annamaria Kisslinger, Antonio A. Sinisi, Ciro Abbondanza, Donatella Tramontano
Pages: 797-801
Published online on: 01 September 2003

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Article

Akt activity in endometrial cancer cells: Regulation of cell survival through cIAP-1

Veronique Gagnon, Marie-Eve St-Germain, Sophie Parent, Eric Asselin
Pages: 803-810
Published online on: 01 September 2003

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Article

Chemoembolization with cisplatin, lipiodol and gelfoam® and subsequent systemic chemotherapy with cisplatin and interferon in patients with hepatocellular carcinoma: a non-randomized prospective study

Martina Baur, Reinhard Walter, Axel Gebauer, Dimiter Tscholakoff, Herbert Lochs, Ferdinand Mühlbacher, Karl Turetschek, Reinhard Binder, Marcus Hudec, Alfred Gangl, Peter Ferenci, Christian Dittrich
Pages: 811-819
Published online on: 01 September 2003

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Article

Inhibition of ErbB-2 and ErbB-3 expression by quercetin prevents transforming growth factor alpha (TGF-α)- and epidermal growth factor (EGF)-induced human PC-3 prostate cancer cell proliferation

Hung Huynh, Thi Thanh Tuyen Nguyen, Eli Chan, Evelyne Tran
Pages: 821-829
Published online on: 01 September 2003

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Article

Identification and characterization of mouse Erbb2 gene in silico

Masuko Katoh, Masaru Katoh
Pages: 831-835
Published online on: 01 September 2003

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Article

Impact of hemoglobin levels before and during chemotherapy on survival of patients with ovarian cancer

Karsten Münstedt, Marijana Kovacic, Marek Zygmunt, Richard Von Georgi
Pages: 837-843
Published online on: 01 September 2003

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Article

Identification and characterization of ASXL2 gene in silico

Masuko Katoh, Masaru Katoh
Pages: 845-850
Published online on: 01 September 2003

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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Article Open Access

lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Review Open Access

Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Review Open Access

Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Review Open Access

Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Review Open Access

Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Selective antitumor and apoptosis‑inducing effects of the Src inhibitor PP1 in human tongue squamous cell carcinoma cells

Shirinbaeva Luiza Kantibekovna, Saini Wang, Hyunju Kang, Young-Min Shin, Byeong-Churl Jang
Article Number: 64
Published online on: 27 March 2026

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Review Open Access

Multifaceted roles of miR‑124 in cancer: Molecular mechanisms and clinical prospects (Review)

Jun Guo, Yunyan Guo, Peiyang Chen, Wenyan Xiao, Yuxiang Tan, Zhiyong Wang, Yanxin Lu, Xupeng Yue
Article Number: 63
Published online on: 24 March 2026

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Article Open Access

Hypoxia‑induced exosomal CAMTA1 promotes radio‑resistance in MDA‑MB‑231 cells by regulating NRG1 to mediate M2 macrophage polarization

Qian Li, Minghua Jiang, Biqing Zhu, Wei Wei, Lei Xia, Jian Huang, Han Gao, Mingyu Du
Article Number: 62
Published online on: 20 March 2026

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Correction Open Access

[Corrigendum] Epithelial protein lost in neoplasm‑α (EPLIN‑α) is a potential prognostic marker for the progression of epithelial ovarian cancer

Rong Liu, Tracey A. Martin, Nicola J. Jordan, Fiona Ruge, Lin Ye, Wen G. Jiang
Article Number: 61
Published online on: 18 March 2026

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Crosstalk between KRAS and miRNAs in pancreatic cancer: Opportunities for its diagnosis, prognosis and therapeutic intervention (Review)

Abdulaziz A. Aloliqi, Abdullah M. Alnuqaydan, Mohammad Alshebremi, Arshad Husain Rahmani, Amjad Ali Khan
Article Number: 60
Published online on: 18 March 2026

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Smoking promotes colorectal cancer via the CKAP2L/AREG axis

Shasha Wu, Feixiang Wu, Xiaoqing Li, Zhihang Jiang, Fuqiang Liu, Zheng Jiang
Article Number: 59
Published online on: 13 March 2026

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Diverse roles of SERPINE1 in regulating cellular proliferation and invasion

Wei Wang, Pengfei Zhao, Tian Wang, Weijing Wu, Jing Li, Qiang Huang, Jing Mo
Article Number: 58
Published online on: 13 March 2026

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Therapeutic implications of targeting cancer testis antigen MAGEA1 in cervical cancer

Ayoung Kim, Jina Kim, Woori Kwak, Kyumin Mo, Soohyun Choe, Minyeong Jeon, Jisun Lee, Jun-Won Yun, Hyunho Yoon
Article Number: 57
Published online on: 12 March 2026

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Review Open Access

Enolase 1: A paradigm of metabolic enzyme moonlighting in tumorigenesis (Review)

Xiaochen Ni, Mingsi Zhang, Kaiyuan Zhang, Chuhang Wang, Jianing Guo, Wei Fan, Linfeng Zheng, Tao Jiang, Guangji Zhang
Article Number: 56
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Article Number: 55
Published online on: 09 March 2026

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Review Open Access

Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review)

Guirui Zhang, Yongmo Wu, Mingzhen Wei, Shupeng Huang, Qinghao Wang, Zhengyi Xie, Sisi Liu, Jin Wang
Article Number: 54
Published online on: 06 March 2026

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Retraction Open Access

[Retracted] Design, synthesis and preclinical evaluation of NRC‑AN‑019

Kompella Amala, A.K.S. Bhujanga Rao, Bharathi Gorantla, Christopher S.  Gondi, Jasti S. Rao
Article Number: 53
Published online on: 04 March 2026

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Article Open Access

FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma

Nawal Merjaneh, Ying-Wei Lan, Zicheng Deng, Johnny Donovan, Guolun Wang, Jonathan Do, Tiffany Juan, Xiaomei Xia, Vladimir V. Kalinichenko, Tanya V. Kalin
Article Number: 52
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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Article Open Access

RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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