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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2007 Volume 30 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Le morte du tumour: Histological features of tumor destruction in chemo-resistant cancers following intravenous infusions of pathotropic nanoparticles bearing therapeutic genes

Erlinda M. Gordon, Maria Teresa Chan, Nelson Geraldino, Francisco F. Lopez, Gerardo H. Cornelio, Conrado C. Lorenzo, John P. Levy, Rebecca A. Reed, Liqiong Liu, Frederick L. Hall
Pages: 1297-1307
Published online on: 01 June 2007

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Article

Immunotherapy for malignant tumors using combination of allogeneic intra-bone marrow-bone marrow transplantation, donor lymphocyte infusion and dendritic cells

Hiromi Mukaide, Yasushi Adachi, Naoko Koike-Kiriyama, Yasuhiro Suzuki, Keizo Minamino, Masayoshi Iwasaki, Masanobu Tsuda, Keiji Nakano, Yasushi Koike, Akio Shigematsu, Yasuo Kamiyama, Susumu Ikehara
Pages: 1309-1315
Published online on: 01 June 2007

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Article

Are overexpressed alternative survivin transcripts in human bladder cancer suitable targets for siRNA-mediated in vitro inhibition?

D. Wuttig, D. Kunze, S. Fuessel, M. Toma, J. Stade, M. Kotzsch, M. Kappler, H. Taubert, B. Schwenzer, G. Baretton, O. W. Hakenberg, A. Meye, M. P. Wirth
Pages: 1317-1324
Published online on: 01 June 2007

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Article

Establishment and characterization of a cisplatin-resistant cell line, KB-R, derived from oral carcinoma cell line, KB

Kenji Negoro, Yukio Yamano, Kazuaki Fushimi, Kengo Saito, Ken Nakatani, Masashi Shiiba, Hidetaka Yokoe, Hiroki Bukawa, Katsuhiro Uzawa, Takeshi Wada, Hideki Tanzawa, Shigeyuki Fujita
Pages: 1325-1332
Published online on: 01 June 2007

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Article

Activated ERK1/2 expression in glioblastoma multiforme and in peritumor tissue

Gina Lama, Annunziato Mangiola, Carmelo Anile, Giovanni Sabatino, Pasquale De Bonis, Libero Lauriola, Cecilia Giannitelli, Giuseppe La Torre, Meena Jhanwar-Uniyal, Gigliola Sica, Giulio Maira
Pages: 1333-1342
Published online on: 01 June 2007

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Article

Downregulation of drs mRNA expression is associated with the progression of adult T-cell leukemia/lymphoma

Misuzu Shimakage, Nobumasa Inoue, Kohichi Ohshima, Kunimitsu Kawahara, Naoki Yamamoto, Takashi Oka, Yukihiro Tambe, Kazuta Yasui, Kayoko Matsumoto, Masuo Yutsudo, Hirokazu Inoue
Pages: 1343-1348
Published online on: 01 June 2007

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Article

Prognostic value of human telomerase reverse transcriptase gene expression in oral carcinogenesis

G. Pannone, S. De Maria, R. Zamparese, S. Metafora, R. Serpico, F. Morelli, C. Rubini, E. Farina, M. Carteni, S. Staibano, G. De Rosa, L. Lo Muzio, P. Bufo
Pages: 1349-1357
Published online on: 01 June 2007

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Article

Expression of hypoxia-inducible factor-1 alpha and associated proteins in pancreatic ductal adenocarcinoma and their impact on prognosis

Hong-Cheng Sun, Zheng-Jun Qiu, Jun Liu, Jing Sun, Tao Jiang, Ke-Jian Huang, Min Yao, Chen Huang
Pages: 1359-1367
Published online on: 01 June 2007

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Article

Transcriptomic profiling of radiation-resistant or -sensitive human colorectal cancer cells: Acute effects of a single X-radiation dose

Cheng E. Ng, Qing Y. Liu, Sami S. Qutob, Bradley J. Scott, Wei L. Tan, Felix M. Mesak
Pages: 1369-1380
Published online on: 01 June 2007

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Article

Overexpression of Pim-1 in head and neck squamous cell carcinomas

Ulf Henning Beier, Jan Bernd Weise, Martin Laudien, Hauke Sauerwein, Tibor Görögh
Pages: 1381-1387
Published online on: 01 June 2007

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Article

The effect of co-expression costimulatory molecule CD80 on uptake of antigen peptide-MHC class I-GFP complex by specific T cells

Xia Liu, Leilei Zhang, Xingqian Zhang, Hai Yu, Xiaoping Zhao, Jian Lu, Guanxiang Qian, Shengfang Ge
Pages: 1389-1396
Published online on: 01 June 2007

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Article

Efficient electrogene therapy for pancreatic adenocarcinoma treatment using the bacterial purine nucleoside phosphorylase suicide gene with fludarabine

Sophie Deharvengt, Soukaina Rejiba, Séverine Wack, Marc Aprahamian, Amor Hajri
Pages: 1397-1406
Published online on: 01 June 2007

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Article

Potential mechanisms for the synergistic cytotoxicity elicited by 4-hydroxytamoxifen and epigallocatechin gallate in MDA-MB-231 cells

Emma C. Stuart, Lesley Larsen, Rhonda J. Rosengren
Pages: 1407-1412
Published online on: 01 June 2007

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Article

Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo

Tadeusz Issat, Dominika Nowis, Magdalena Legat, Marcin Makowski, Marcin P. Klejman, Jakub Urbanski, Janusz Skierski, Miroslawa Koronkiewicz, Tomasz Stoklosa, Agnieszka Brzezinska, Jacek Bil, Jan Gietka, Marek Jakóbisiak, Jakub Golab
Pages: 1413-1425
Published online on: 01 June 2007

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Article

Non-viral delivery of the connexin 43 gene with histone deacetylase inhibitor to human nasopharyngeal tumor cells enhances gene expression and inhibits in vivo tumor growth

Yoshiyuki Hattori, Masayoshi Fukushima, Yoshie Maitani
Pages: 1427-1439
Published online on: 01 June 2007

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Article

DMBT1 is frequently downregulated in well-differentiated gastric carcinoma but more frequently upregulated across various gastric cancer types

Ana R. Conde, Ana P. Martins, Miguel Brito, Armandina Manuel, Sancia Ramos, Joana Malta-Vacas, Marcus Renner, Annemarie Poustka, Jan Mollenhauer, Carolino Monteiro
Pages: 1441-1446
Published online on: 01 June 2007

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Article

siRNA-mediated MDM2 inhibition sensitizes human lung cancer A549 cells to radiation

Wanfeng Guo, Kazi Mokim Ahmed, Yanpin Hui, Guozheng Guo, Jian Jian Li
Pages: 1447-1452
Published online on: 01 June 2007

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Article

A natural peptide, dolastatin 15, induces G2/M cell cycle arrest and apoptosis of human multiple myeloma cells

Masanori Sato, Morihiko Sagawa, Tomonori Nakazato, Yasuo Ikeda, Masahiro Kizaki
Pages: 1453-1459
Published online on: 01 June 2007

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Article

Flt3 ligand promotes myeloid dendritic cell differentiation of human hematopoietic progenitor cells: Possible application for cancer immunotherapy

Sachio Harada, Takafumi Kimura, Hiroshi Fujiki, Hitoshi Nakagawa, Yuji Ueda, Tsuyoshi Itoh, Hisakazu Yamagishi, Yoshiaki Sonoda
Pages: 1461-1468
Published online on: 01 June 2007

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Article

Effect of combining epidermal growth factor receptor inhibitors and cisplatin on proliferation and apoptosis of oral squamous cell carcinoma cells

Sayaka Takaoka, Masayasu Iwase, Makiko Uchida, Sayaka Yoshiba, Gen Kondo, Hitoshi Watanabe, Masaru Ohashi, Masao Nagumo, Satoru Shintani
Pages: 1469-1476
Published online on: 01 June 2007

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Article

Silencing Ku80 using small interfering RNA enhanced radiation sensitivity in vitro and in vivo

Yoshinori Nimura, Tetsuya Kawata, Katsuhiro Uzawa, Junko Okamura, Cuihua Liu, Masayoshi Saito, Hideaki Shimada, Naohiko Seki, Akira Nakagawara, Hisao Ito, Takenori Ochiai, Hideki Tanzawa
Pages: 1477-1484
Published online on: 01 June 2007

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Article

LH-RH receptors in human colorectal cancers: Unexpected molecular targets for experimental therapy

Karoly Szepeshazi, Andrew V. Schally, Gabor Halmos
Pages: 1485-1492
Published online on: 01 June 2007

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Article

Kallikrein 11 expressed in human breast cancer cells releases insulin-like growth factor through degradation of IGFBP-3

Atsumi Sano, Takafumi Sangai, Hiroyuki Maeda, Michio Nakamura, Takahiro Hasebe, Atsushi Ochiai
Pages: 1493-1498
Published online on: 01 June 2007

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Article

Effects of leptin on human breast cancer cell lines in relationship to estrogen receptor and HER2 status

Amitabha Ray, Katai J. Nkhata, Margot P. Cleary
Pages: 1499-1509
Published online on: 01 June 2007

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Article

Experimental therapy for colon cancer: Anti-cancer effects of TLR9 agonism, combination with other therapeutic modalities, and dependence upon p53

Elizabeth R. Rayburn, Wei Wang, Ruiwen Zhang, Hui Wang
Pages: 1511-1519
Published online on: 01 June 2007

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Review

Viral infections as a cause of cancer (Review)

C. Carrillo-Infante, G. Abbadessa, L. Bagella, A. Giordano
Pages: 1521-1528
Published online on: 01 June 2007

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Article

Honokiol, a natural biphenyl, inhibits in vitro and in vivo growth of breast cancer through induction of apoptosis and cell cycle arrest

Ido Wolf, James O'Kelly, Naoki Wakimoto, Anh Nguyen, Franck Amblard, Beth Y. Karlan, Jack L. Arbiser, H. Phillip Koeffler
Pages: 1529-1537
Published online on: 01 June 2007

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Article

Induction of colon tumorigenesis by glutathione depletion in p53-knock-out mice

John P. Richie, Despina Komninou, Anthony P. Albino
Pages: 1539-1543
Published online on: 01 June 2007

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Article

Proteomic profiling of MCF-7 breast cancer cells with chemoresistance to different types of anti-cancer drugs

Suebwong Chuthapisith, Robert Layfield, Ian D. Kerr, Catherine Hughes, Oleg Eremin
Pages: 1545-1551
Published online on: 01 June 2007

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Article

The interactive transcript abundance index [c-myc*p73α]/[p21*Bcl-2] correlates with baseline level of apoptosis and response to CPT-11 in human bronchogenic carcinoma cell lines

Michael W. Harr, James C. Willey
Pages: 1553-1560
Published online on: 01 June 2007

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Article

Antitumor effects of two newly constructed oncolytic herpes simplex viruses against renal cell carcinoma

Xinping Fu, Mikihito Nakamori, Lihua Tao, Robert Amato, Xiaoliu Zhang
Pages: 1561-1567
Published online on: 01 June 2007

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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