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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2007 Volume 30 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Le morte du tumour: Histological features of tumor destruction in chemo-resistant cancers following intravenous infusions of pathotropic nanoparticles bearing therapeutic genes

Erlinda M. Gordon, Maria Teresa Chan, Nelson Geraldino, Francisco F. Lopez, Gerardo H. Cornelio, Conrado C. Lorenzo, John P. Levy, Rebecca A. Reed, Liqiong Liu, Frederick L. Hall
Pages: 1297-1307
Published online on: 01 June 2007

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Article

Immunotherapy for malignant tumors using combination of allogeneic intra-bone marrow-bone marrow transplantation, donor lymphocyte infusion and dendritic cells

Hiromi Mukaide, Yasushi Adachi, Naoko Koike-Kiriyama, Yasuhiro Suzuki, Keizo Minamino, Masayoshi Iwasaki, Masanobu Tsuda, Keiji Nakano, Yasushi Koike, Akio Shigematsu, Yasuo Kamiyama, Susumu Ikehara
Pages: 1309-1315
Published online on: 01 June 2007

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Article

Are overexpressed alternative survivin transcripts in human bladder cancer suitable targets for siRNA-mediated in vitro inhibition?

D. Wuttig, D. Kunze, S. Fuessel, M. Toma, J. Stade, M. Kotzsch, M. Kappler, H. Taubert, B. Schwenzer, G. Baretton, O. W. Hakenberg, A. Meye, M. P. Wirth
Pages: 1317-1324
Published online on: 01 June 2007

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Article

Establishment and characterization of a cisplatin-resistant cell line, KB-R, derived from oral carcinoma cell line, KB

Kenji Negoro, Yukio Yamano, Kazuaki Fushimi, Kengo Saito, Ken Nakatani, Masashi Shiiba, Hidetaka Yokoe, Hiroki Bukawa, Katsuhiro Uzawa, Takeshi Wada, Hideki Tanzawa, Shigeyuki Fujita
Pages: 1325-1332
Published online on: 01 June 2007

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Article

Activated ERK1/2 expression in glioblastoma multiforme and in peritumor tissue

Gina Lama, Annunziato Mangiola, Carmelo Anile, Giovanni Sabatino, Pasquale De Bonis, Libero Lauriola, Cecilia Giannitelli, Giuseppe La Torre, Meena Jhanwar-Uniyal, Gigliola Sica, Giulio Maira
Pages: 1333-1342
Published online on: 01 June 2007

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Article

Downregulation of drs mRNA expression is associated with the progression of adult T-cell leukemia/lymphoma

Misuzu Shimakage, Nobumasa Inoue, Kohichi Ohshima, Kunimitsu Kawahara, Naoki Yamamoto, Takashi Oka, Yukihiro Tambe, Kazuta Yasui, Kayoko Matsumoto, Masuo Yutsudo, Hirokazu Inoue
Pages: 1343-1348
Published online on: 01 June 2007

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Article

Prognostic value of human telomerase reverse transcriptase gene expression in oral carcinogenesis

G. Pannone, S. De Maria, R. Zamparese, S. Metafora, R. Serpico, F. Morelli, C. Rubini, E. Farina, M. Carteni, S. Staibano, G. De Rosa, L. Lo Muzio, P. Bufo
Pages: 1349-1357
Published online on: 01 June 2007

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Article

Expression of hypoxia-inducible factor-1 alpha and associated proteins in pancreatic ductal adenocarcinoma and their impact on prognosis

Hong-Cheng Sun, Zheng-Jun Qiu, Jun Liu, Jing Sun, Tao Jiang, Ke-Jian Huang, Min Yao, Chen Huang
Pages: 1359-1367
Published online on: 01 June 2007

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Article

Transcriptomic profiling of radiation-resistant or -sensitive human colorectal cancer cells: Acute effects of a single X-radiation dose

Cheng E. Ng, Qing Y. Liu, Sami S. Qutob, Bradley J. Scott, Wei L. Tan, Felix M. Mesak
Pages: 1369-1380
Published online on: 01 June 2007

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Article

Overexpression of Pim-1 in head and neck squamous cell carcinomas

Ulf Henning Beier, Jan Bernd Weise, Martin Laudien, Hauke Sauerwein, Tibor Görögh
Pages: 1381-1387
Published online on: 01 June 2007

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Article

The effect of co-expression costimulatory molecule CD80 on uptake of antigen peptide-MHC class I-GFP complex by specific T cells

Xia Liu, Leilei Zhang, Xingqian Zhang, Hai Yu, Xiaoping Zhao, Jian Lu, Guanxiang Qian, Shengfang Ge
Pages: 1389-1396
Published online on: 01 June 2007

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Article

Efficient electrogene therapy for pancreatic adenocarcinoma treatment using the bacterial purine nucleoside phosphorylase suicide gene with fludarabine

Sophie Deharvengt, Soukaina Rejiba, Séverine Wack, Marc Aprahamian, Amor Hajri
Pages: 1397-1406
Published online on: 01 June 2007

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Article

Potential mechanisms for the synergistic cytotoxicity elicited by 4-hydroxytamoxifen and epigallocatechin gallate in MDA-MB-231 cells

Emma C. Stuart, Lesley Larsen, Rhonda J. Rosengren
Pages: 1407-1412
Published online on: 01 June 2007

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Article

Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo

Tadeusz Issat, Dominika Nowis, Magdalena Legat, Marcin Makowski, Marcin P. Klejman, Jakub Urbanski, Janusz Skierski, Miroslawa Koronkiewicz, Tomasz Stoklosa, Agnieszka Brzezinska, Jacek Bil, Jan Gietka, Marek Jakóbisiak, Jakub Golab
Pages: 1413-1425
Published online on: 01 June 2007

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Article

Non-viral delivery of the connexin 43 gene with histone deacetylase inhibitor to human nasopharyngeal tumor cells enhances gene expression and inhibits in vivo tumor growth

Yoshiyuki Hattori, Masayoshi Fukushima, Yoshie Maitani
Pages: 1427-1439
Published online on: 01 June 2007

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Article

DMBT1 is frequently downregulated in well-differentiated gastric carcinoma but more frequently upregulated across various gastric cancer types

Ana R. Conde, Ana P. Martins, Miguel Brito, Armandina Manuel, Sancia Ramos, Joana Malta-Vacas, Marcus Renner, Annemarie Poustka, Jan Mollenhauer, Carolino Monteiro
Pages: 1441-1446
Published online on: 01 June 2007

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Article

siRNA-mediated MDM2 inhibition sensitizes human lung cancer A549 cells to radiation

Wanfeng Guo, Kazi Mokim Ahmed, Yanpin Hui, Guozheng Guo, Jian Jian Li
Pages: 1447-1452
Published online on: 01 June 2007

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Article

A natural peptide, dolastatin 15, induces G2/M cell cycle arrest and apoptosis of human multiple myeloma cells

Masanori Sato, Morihiko Sagawa, Tomonori Nakazato, Yasuo Ikeda, Masahiro Kizaki
Pages: 1453-1459
Published online on: 01 June 2007

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Article

Flt3 ligand promotes myeloid dendritic cell differentiation of human hematopoietic progenitor cells: Possible application for cancer immunotherapy

Sachio Harada, Takafumi Kimura, Hiroshi Fujiki, Hitoshi Nakagawa, Yuji Ueda, Tsuyoshi Itoh, Hisakazu Yamagishi, Yoshiaki Sonoda
Pages: 1461-1468
Published online on: 01 June 2007

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Article

Effect of combining epidermal growth factor receptor inhibitors and cisplatin on proliferation and apoptosis of oral squamous cell carcinoma cells

Sayaka Takaoka, Masayasu Iwase, Makiko Uchida, Sayaka Yoshiba, Gen Kondo, Hitoshi Watanabe, Masaru Ohashi, Masao Nagumo, Satoru Shintani
Pages: 1469-1476
Published online on: 01 June 2007

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Article

Silencing Ku80 using small interfering RNA enhanced radiation sensitivity in vitro and in vivo

Yoshinori Nimura, Tetsuya Kawata, Katsuhiro Uzawa, Junko Okamura, Cuihua Liu, Masayoshi Saito, Hideaki Shimada, Naohiko Seki, Akira Nakagawara, Hisao Ito, Takenori Ochiai, Hideki Tanzawa
Pages: 1477-1484
Published online on: 01 June 2007

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Article

LH-RH receptors in human colorectal cancers: Unexpected molecular targets for experimental therapy

Karoly Szepeshazi, Andrew V. Schally, Gabor Halmos
Pages: 1485-1492
Published online on: 01 June 2007

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Article

Kallikrein 11 expressed in human breast cancer cells releases insulin-like growth factor through degradation of IGFBP-3

Atsumi Sano, Takafumi Sangai, Hiroyuki Maeda, Michio Nakamura, Takahiro Hasebe, Atsushi Ochiai
Pages: 1493-1498
Published online on: 01 June 2007

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Article

Effects of leptin on human breast cancer cell lines in relationship to estrogen receptor and HER2 status

Amitabha Ray, Katai J. Nkhata, Margot P. Cleary
Pages: 1499-1509
Published online on: 01 June 2007

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Article

Experimental therapy for colon cancer: Anti-cancer effects of TLR9 agonism, combination with other therapeutic modalities, and dependence upon p53

Elizabeth R. Rayburn, Wei Wang, Ruiwen Zhang, Hui Wang
Pages: 1511-1519
Published online on: 01 June 2007

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Review

Viral infections as a cause of cancer (Review)

C. Carrillo-Infante, G. Abbadessa, L. Bagella, A. Giordano
Pages: 1521-1528
Published online on: 01 June 2007

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Article

Honokiol, a natural biphenyl, inhibits in vitro and in vivo growth of breast cancer through induction of apoptosis and cell cycle arrest

Ido Wolf, James O'Kelly, Naoki Wakimoto, Anh Nguyen, Franck Amblard, Beth Y. Karlan, Jack L. Arbiser, H. Phillip Koeffler
Pages: 1529-1537
Published online on: 01 June 2007

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Article

Induction of colon tumorigenesis by glutathione depletion in p53-knock-out mice

John P. Richie, Despina Komninou, Anthony P. Albino
Pages: 1539-1543
Published online on: 01 June 2007

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Article

Proteomic profiling of MCF-7 breast cancer cells with chemoresistance to different types of anti-cancer drugs

Suebwong Chuthapisith, Robert Layfield, Ian D. Kerr, Catherine Hughes, Oleg Eremin
Pages: 1545-1551
Published online on: 01 June 2007

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Article

The interactive transcript abundance index [c-myc*p73α]/[p21*Bcl-2] correlates with baseline level of apoptosis and response to CPT-11 in human bronchogenic carcinoma cell lines

Michael W. Harr, James C. Willey
Pages: 1553-1560
Published online on: 01 June 2007

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Article

Antitumor effects of two newly constructed oncolytic herpes simplex viruses against renal cell carcinoma

Xinping Fu, Mikihito Nakamori, Lihua Tao, Robert Amato, Xiaoliu Zhang
Pages: 1561-1567
Published online on: 01 June 2007

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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Article Open Access

lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Review Open Access

Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Review Open Access

Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Review Open Access

Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Selective antitumor and apoptosis‑inducing effects of the Src inhibitor PP1 in human tongue squamous cell carcinoma cells

Shirinbaeva Luiza Kantibekovna, Saini Wang, Hyunju Kang, Young-Min Shin, Byeong-Churl Jang
Article Number: 64
Published online on: 27 March 2026

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Multifaceted roles of miR‑124 in cancer: Molecular mechanisms and clinical prospects (Review)

Jun Guo, Yunyan Guo, Peiyang Chen, Wenyan Xiao, Yuxiang Tan, Zhiyong Wang, Yanxin Lu, Xupeng Yue
Article Number: 63
Published online on: 24 March 2026

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Article Open Access

Hypoxia‑induced exosomal CAMTA1 promotes radio‑resistance in MDA‑MB‑231 cells by regulating NRG1 to mediate M2 macrophage polarization

Qian Li, Minghua Jiang, Biqing Zhu, Wei Wei, Lei Xia, Jian Huang, Han Gao, Mingyu Du
Article Number: 62
Published online on: 20 March 2026

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Correction Open Access

[Corrigendum] Epithelial protein lost in neoplasm‑α (EPLIN‑α) is a potential prognostic marker for the progression of epithelial ovarian cancer

Rong Liu, Tracey A. Martin, Nicola J. Jordan, Fiona Ruge, Lin Ye, Wen G. Jiang
Article Number: 61
Published online on: 18 March 2026

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Review Open Access

Crosstalk between KRAS and miRNAs in pancreatic cancer: Opportunities for its diagnosis, prognosis and therapeutic intervention (Review)

Abdulaziz A. Aloliqi, Abdullah M. Alnuqaydan, Mohammad Alshebremi, Arshad Husain Rahmani, Amjad Ali Khan
Article Number: 60
Published online on: 18 March 2026

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Article Open Access

Smoking promotes colorectal cancer via the CKAP2L/AREG axis

Shasha Wu, Feixiang Wu, Xiaoqing Li, Zhihang Jiang, Fuqiang Liu, Zheng Jiang
Article Number: 59
Published online on: 13 March 2026

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Article Open Access

Diverse roles of SERPINE1 in regulating cellular proliferation and invasion

Wei Wang, Pengfei Zhao, Tian Wang, Weijing Wu, Jing Li, Qiang Huang, Jing Mo
Article Number: 58
Published online on: 13 March 2026

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Therapeutic implications of targeting cancer testis antigen MAGEA1 in cervical cancer

Ayoung Kim, Jina Kim, Woori Kwak, Kyumin Mo, Soohyun Choe, Minyeong Jeon, Jisun Lee, Jun-Won Yun, Hyunho Yoon
Article Number: 57
Published online on: 12 March 2026

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Review Open Access

Enolase 1: A paradigm of metabolic enzyme moonlighting in tumorigenesis (Review)

Xiaochen Ni, Mingsi Zhang, Kaiyuan Zhang, Chuhang Wang, Jianing Guo, Wei Fan, Linfeng Zheng, Tao Jiang, Guangji Zhang
Article Number: 56
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Article Number: 55
Published online on: 09 March 2026

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Review Open Access

Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review)

Guirui Zhang, Yongmo Wu, Mingzhen Wei, Shupeng Huang, Qinghao Wang, Zhengyi Xie, Sisi Liu, Jin Wang
Article Number: 54
Published online on: 06 March 2026

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Retraction Open Access

[Retracted] Design, synthesis and preclinical evaluation of NRC‑AN‑019

Kompella Amala, A.K.S. Bhujanga Rao, Bharathi Gorantla, Christopher S.  Gondi, Jasti S. Rao
Article Number: 53
Published online on: 04 March 2026

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Article Open Access

FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma

Nawal Merjaneh, Ying-Wei Lan, Zicheng Deng, Johnny Donovan, Guolun Wang, Jonathan Do, Tiffany Juan, Xiaomei Xia, Vladimir V. Kalinichenko, Tanya V. Kalin
Article Number: 52
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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Article Open Access

RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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