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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2007 Volume 17 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Current advances in the basic research and clinical management of sinonasal inverted papilloma (Review)

Alexander Sauter, Rubina Matharu, Karl Hörmann, Ramin Naim
Pages: 495-504
Published online on: 01 March 2007

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Article

Expression of factors involved in regulation of DNA mismatch repair- and apoptosis pathways in ovarian cancer patients

Verena Materna, Pawel Surowiak, Ewa Markwitz, Marek Spaczynski, Malgorzata Drag-Zalesinska, Maciej Zabel, Hermann Lage
Pages: 505-516
Published online on: 01 March 2007

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Article

Snail plays a key role in E-cadherin-preserved esophageal squamous cell carcinoma

Shoji Natsugoe, Yasuto Uchikado, Hiroshi Okumura, Masataka Matsumoto, Tetsuro Setoyama, Kiyokazu Tamotsu, Yoshiaki Kita, Akihiko Sakamoto, Testuhiro Owaki, Sumiya Ishigami, Takashi Aikou
Pages: 517-523
Published online on: 01 March 2007

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Article

Evaluation of risk of liver metastasis in colorectal adenocarcinoma based on the combination of risk factors including CD10 expression: Multivariate analysis of clinicopathological and immunohistochemical factors

Yutaka Ohji, Takashi Yao, Takashi Eguchi, Tomomi Yamada, Minako Hirahashi, Mitsuo Iida, Masazumi Tsuneyoshi
Pages: 525-530
Published online on: 01 March 2007

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Article

Frequent immunoexpression of TGF-β1, FGF-2 and BMP-2 in fibroblast-like cells in osteofibrous dysplasia

Akio Sakamoto, Yoshinao Oda, Yukihide Iwamoto, Masazumi Tsuneyoshi
Pages: 531-535
Published online on: 01 March 2007

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Article

Photosensitizer effect of curcumin on UVB-irradiated HaCaT cells through activation of caspase pathways

Kun Park, Ji-Hye Lee
Pages: 537-540
Published online on: 01 March 2007

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Article

A diagnostic evaluation of serum human telomerase reverse transcriptase mRNA as a novel tumor marker for gynecologic malignancies

Norimasa Miura, Yasunobu Kanamori, Masakuni Takahashi, Reina Sato, Tomoe Tsukamoto, Shunsaku Takahashi, Tomomi Harada, Akiko Sano, Kohei Shomori, Tasuku Harada, Junzou Kigawa, Hisao Ito, Naoki Terakawa, Junichi Hasegawa, Goshi Shiota
Pages: 541-548
Published online on: 01 March 2007

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Article

SIAH1 causes growth arrest and apoptosis in hepatoma cells through β-catenin degradation-dependent and -independent mechanisms

Hiroshi Yoshibayashi, Hiroshi Okabe, Seiji Satoh, Koya Hida, Kazuhiko Kawashima, Shinya Hamasu, Akinari Nomura, Suguru Hasegawa, Iwao Ikai, Yoshiharu Sakai
Pages: 549-556
Published online on: 01 March 2007

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Article

Co-expression of aFGF and FGFR-1 is predictive of a poor prognosis in patients with esophageal squamous cell carcinoma

Koichi Sugiura, Soji Ozawa, Yuko Kitagawa, Masakazu Ueda, Masaki Kitajima
Pages: 557-564
Published online on: 01 March 2007

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Article

Genetic polymorphism and gene expression of microsomal epoxide hydrolase in non-small cell lung cancer

Torng-Sen Lin, Hsuan-Hua Huang, Yi-Hsin Fan, Shiow-Her Chiou, Kuan-Chih Chow
Pages: 565-572
Published online on: 01 March 2007

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Article

Modification of gene expression by melatonin in UVB-irradiated HaCaT keratinocyte cell lines using a cDNA microarray

Jae-We Cho, Chang-Wook Kim, Kyu-Suk Lee
Pages: 573-577
Published online on: 01 March 2007

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Article

Cytological findings of pre-invasive bronchial lesions detected by light-induced fluorescence endoscopy in a lung cancer screening system

Masayuki Baba, Akira Iyoda, Yasushi Nomoto, Kiyoshi Shibuya, Kenzo Hiroshima, Hiroko Saito, Akemi Taguchi, Katsuhiro Kounoike, Fumie Saegusa, Takeichiro Kuwahara, Hirohiko Tsujii, Takehiko Fujisawa
Pages: 579-583
Published online on: 01 March 2007

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Article

Leydig cell tumors of the testis: A molecular-cytogenetic study based on a large series of patients

I. Verdorfer, D. Horst, A. Höllrigl, M. Susani, A. Hartmann, H. Rogatsch, G. Mikuz
Pages: 585-589
Published online on: 01 March 2007

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Article

Immunohistochemical expression of heparin-binding protein 17/fibroblast growth factor-binding protein-1 (HBp17/FGFBP-1) as an angiogenic factor in head and neck tumorigenesis

Shahana Begum, Yan Zhang, Tomoaki Shintani, Shigeaki Toratani, J. Denry Sato, Tetsuji Okamoto
Pages: 591-596
Published online on: 01 March 2007

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Article

Lidamycin induces marked G2 cell cycle arrest in human colon carcinoma HT-29 cells through activation of p38 MAPK pathway

Xia Liu, Chunjing Bian, Kaihuan Ren, Haixia Jin, Baowei Li, Rong-Guang Shao
Pages: 597-603
Published online on: 01 March 2007

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Article

BNIPL-2 promotes the invasion and metastasis of human hepatocellular carcinoma cells

Li Xie, Wenxin Qin, Jinjun Li, Xianghuo He, Haitao Zhang, Genfu Yao, Huiqun Shu, Ming Yao, Dafang Wan, Jianren Gu
Pages: 605-610
Published online on: 01 March 2007

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Article

S-phase reduction in T47D human breast cancer epithelial cells induced by an S100P antisense-retroviral construct

Bettina Beissel, Ismael D.C.G. Silva, João B. Pesquero, Jose Russo, Nestor Schor, Maria Helena Bellini
Pages: 611-615
Published online on: 01 March 2007

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Article

Preventive effects of glycyrrhizin on estrogen-related endometrial carcinogenesis in mice

Kenji Niwa, Zenglin Lian, Kyoko Onogi, Wu Yun, Liulin Tang, Hideki Mori, Teruhiko Tamaya
Pages: 617-622
Published online on: 01 March 2007

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Article

Clinical significance of RCAS1 as a biomarker of ovarian cancer

Kenzo Sonoda, Shingo Miyamoto, Fusanori Yotsumoto, Hiroshi Yagi, Manabu Nakashima, Takeshi Watanabe, Hitoo Nakano
Pages: 623-628
Published online on: 01 March 2007

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Article

Kinesin superfamily protein-derived peptides with the ability to induce glioma-reactive cytotoxic T lymphocytes in human leukocyte antigen-A24+ glioma patients

Mamoru Harada, Yuki Ishihara, Kyogo Itoh, Ryuya Yamanaka
Pages: 629-636
Published online on: 01 March 2007

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Article

Combined analysis of genetic polymorphisms in thymidylate synthase, uridine diphosphate glucoronosyltransferase and X-ray cross complementing factor 1 genes as a prognostic factor in advanced colorectal cancer patients treated with 5-fluorouracil plus oxaliplatin or irinotecan

Eva Martinez-Balibrea, Jose Luis Manzano, Anna Martinez-Cardus, Teresa Moran, Beatriz Cirauqui, Silvia Catot, Miguel Taron, Albert Abad
Pages: 637-645
Published online on: 01 March 2007

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Article

Regulation of the HIF-1α stability by histone deacetylases

Se-Hee Kim, Joo-Won Jeong, Jeong Ae Park, Ji-Won Lee, Ji Hae Seo, Bo-Kyung Jung, Moon-Kyoung Bae, Kyu-Won Kim
Pages: 647-651
Published online on: 01 March 2007

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Article

Hyperthermia-enhanced tumor accumulation and antitumor efficacy of a doxorubicin-conjugate with a novel macromolecular carrier system in mice with non-small cell lung cancer

Takahiko Oyama, Masafumi Kawamura, Tomohiro Abiko, Yotaro Izumi, Masazumi Watanabe, Eiji Kumazawa, Hiroshi Kuga, Yoshinobu Shiose, Koichi Kobayashi
Pages: 653-659
Published online on: 01 March 2007

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Article

Microsatellite DNA instability in nasal cytology of COPD patients

Alexander D. Karatzanis, Katerina D. Samara, Eleni Tzortzaki, Maria Zervou, Emmanuel S. Helidonis, George A. Velegrakis, Nikolaos Siafakas
Pages: 661-665
Published online on: 01 March 2007

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Article

Prospective study of the quantitative carcinoembryonic antigen and cytokeratin 20 mRNA detection in peritoneal washes to predict peritoneal recurrence in gastric carcinoma patients

Naoyuki Tamura, Hisae Iinuma, Tadahiro Takada
Pages: 667-672
Published online on: 01 March 2007

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Article

Cimetidine induces apoptosis of human salivary gland tumor cells

Masakatsu Fukuda, Shin Tanaka, Seiji Suzuki, Kaoru Kusama, Tadayoshi Kaneko, Hideaki Sakashita
Pages: 673-678
Published online on: 01 March 2007

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Article

Induction of multiple CD8+ T cell responses against the inducible Hsp70 employing an Hsp70 oligoepitope peptide

Olivier Faure, Stéphanie Graff-Dubois, Pedro M.S. Alves, Sébastien Cornet, Marie-Thérèse Duffour, Antonio Scardino, David-Alexandre Gross, Isabelle Miconnet, Margarita Salcedo, Salem Chouaib, François A. Lemonnier, Jean-Pierre Abastado, Kostas Kosmatopoulos
Pages: 679-685
Published online on: 01 March 2007

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Article

Assessing serum cytokine profiles in breast cancer patients receiving a HER2/neu vaccine using Luminex® technology

Zia A. Dehqanzada, Catherine E. Storrer, Matthew T. Hueman, Rebecca J. Foley, Katie A. Harris, Yusuf H. Jama, Craig D. Shriver, Sathibalan Ponniah, George E. Peoples
Pages: 687-694
Published online on: 01 March 2007

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Article

Low postabsorptive net protein degradation in male cancer patients: Lack of sensitivity to regulatory amino acids?

Eggert Holm, Wulf Hildebrandt, Ralf Kinscherf, Wulf Dröge
Pages: 695-700
Published online on: 01 March 2007

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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