|
1
|
Torre LA, Bray F, Siegel RL, Ferlay J,
Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA
Cancer J Clin. 65:87–108. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Mamelle G, Pampurik J, Luboinski B, Lancar
R, Lusinchi A and Bosq J: Lymph node prognostic factors in head and
neck squamous cell carcinomas. Am J Surg. 168:494–498. 1994.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Quail DF and Joyce JA: Microenvironmental
regulation of tumor progression and metastasis. Nat Med.
19:1423–1437. 2013. View
Article : Google Scholar : PubMed/NCBI
|
|
4
|
Vaupel P and Mayer A: Hypoxia in cancer:
Significance and impact on clinical outcome. Cancer Metastasis Rev.
26:225–239. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Rankin EB and Giaccia AJ: Hypoxic control
of metastasis. Science. 352:175–180. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Palazon A, Goldrath AW, Nizet V and
Johnson RS: HIF transcription factors, inflammation, and immunity.
Immunity. 41:518–528. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Liu W, Shen SM, Zhao XY and Chen GQ:
Targeted genes and interacting proteins of hypoxia inducible
factor-1. Int J Biochem Mol Biol. 3:165–178. 2012.PubMed/NCBI
|
|
8
|
Kim JW, Tchernyshyov I, Semenza GL and
Dang CV: HIF-1-mediated expression of pyruvate dehydrogenase
kinase: A metabolic switch required for cellular adaptation to
hypoxia. Cell Metab. 3:177–185. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Lu J, Tan M and Cai Q: The Warburg effect
in tumor progression: Mitochondrial oxidative metabolism as an
anti-metastasis mechanism. Cancer Lett. 356:156–164. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Verdone JE, Zarif JC and Pienta KJ:
Aerobic glycolysis, motility, and cytoskeletal remodeling. Cell
Cycle. 14:169–170. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Emdad L, Das SK, Hu B, Kegelman T, Kang
DC, Lee SG, Sarkar D and Fisher PB: AEG-1/MTDH/LYRIC: A promiscuous
protein partner critical in cancer, obesity, and CNS diseases. Adv
Cancer Res. 131:97–132. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Liu Y, Su Z, Li G, Yu C, Ren S, Huang D,
Fan S, Tian Y, Zhang X and Qiu Y: Increased expression of
metadherin protein predicts worse disease-free and overall survival
in laryngeal squamous cell carcinoma. Int J Cancer. 133:671–679.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Yu C, Liu Y, Tan H, Li G, Su Z, Ren S, Zhu
G, Tian Y, Qiu Y and Zhang X: Metadherin regulates metastasis of
squamous cell carcinoma of the head and neck via AKT signalling
pathway-mediated epithelial-mesenchymal transition. Cancer Lett.
343:258–267. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Zhu GC, Yu CY, She L, Tan HL, Li G, Ren
SL, Su ZW, Wei M, Huang DH, Tian YQ, et al: Metadherin regulation
of vascular endothelial growth factor expression is dependent upon
the PI3K/Akt pathway in squamous cell carcinoma of the head and
neck. Medicine. 94:e5022015. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Noch E, Bookland M and Khalili K:
Astrocyte-elevated gene-1 (AEG-1) induction by hypoxia and glucose
deprivation in glioblastoma. Cancer Biol Ther. 11:32–39. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Zhu G, Cai G, Liu Y, Tan H, Yu C, Huang M,
Wei M, Li S, Cui X, Huang D, et al: Quantitative iTRAQ LC-MS/MS
proteomics reveals transcription factor crosstalk and regulatory
networks in hypopharyngeal squamous cell carcinoma. J Cancer.
5:525–536. 2014. View
Article : Google Scholar : PubMed/NCBI
|
|
17
|
Pouysségur J, Dayan F and Mazure NM:
Hypoxia signalling in cancer and approaches to enforce tumour
regression. Nature. 441:437–443. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Shan Y, Li X, You B, Shi S, Zhang Q and
You Y: MicroRNA-338 inhibits migration and proliferation by
targeting hypoxia-induced factor 1α in nasopharyngeal carcinoma.
Oncol Rep. 34:1943–1952. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Yee Koh M, Spivak-Kroizman TR and Powis G:
HIF-1 regulation: Not so easy come, easy go. Trends Biochem Sci.
33:526–534. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Gupta T, Master Z, Kannan S, Agarwal JP,
Ghsoh-Laskar S, Rangarajan V, Murthy V and Budrukkar A: Diagnostic
performance of post-treatment FDG PET or FDG PET/CT imaging in head
and neck cancer: A systematic review and meta-analysis. Eur J Nucl
Med Mol Imaging. 38:2083–2095. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Blatt S, Voelxen N, Sagheb K, Pabst AM,
Walenta S, Schroeder T, Mueller-Klieser W and Ziebart T: Lactate as
a predictive marker for tumor recurrence in patients with head and
neck squamous cell carcinoma (HNSCC) post radiation: A prospective
study over 15 years. Clin Oral Investig. 20:2097–2104. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Koukourakis MI, Giatromanolaki A, Winter
S, Leek R, Sivridis E and Harris AL: Lactate dehydrogenase 5
expression in squamous cell head and neck cancer relates to
prognosis following radical or postoperative radiotherapy.
Oncology. 77:285–292. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Payen VL, Porporato PE, Baselet B and
Sonveaux P: Metabolic changes associated with tumor metastasis,
part 1: Tumor pH, glycolysis and the pentose phosphate pathway.
Cell Mol Life Sci. 73:1333–1348. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Doherty JR and Cleveland JL: Targeting
lactate metabolism for cancer therapeutics. J Clin Invest.
123:3685–3692. 2013. View
Article : Google Scholar : PubMed/NCBI
|
|
25
|
Pinheiro C, Longatto-Filho A, Ferreira L,
Pereira SM, Etlinger D, Moreira MA, Jubé LF, Queiroz GS, Schmitt F
and Baltazar F: Increasing expression of monocarboxylate
transporters 1 and 4 along progression to invasive cervical
carcinoma. Int J Gynecol Pathol. 27:568–574. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Levenson AS, Thurn KE, Simons LA,
Veliceasa D, Jarrett J, Osipo C, Jordan VC, Volpert OV, Satcher RL
Jr and Gartenhaus RB: MCT-1 oncogene contributes to increased in
vivo tumorigenicity of MCF7 cells by promotion of angiogenesis and
inhibition of apoptosis. Cancer Res. 65:10651–10656. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Gallagher SM, Castorino JJ, Wang D and
Philp NJ: Monocarboxylate transporter 4 regulates maturation and
trafficking of CD147 to the plasma membrane in the metastatic
breast cancer cell line MDA-MB-231. Cancer Res. 67:4182–4189. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Lee S-G, Kang D-C, DeSalle R, Sarkar D and
Fisher PB: AEG-1/MTDH/LYRIC, the beginning: Initial cloning,
structure, expression profile, and regulation of expression. Adv
Cancer Res. 120:1–38. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Podar K and Anderson KC: A therapeutic
role for targeting c-Myc/Hif-1-dependent signaling pathways. Cell
Cycle. 9:1722–1728. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Lee SG, Su ZZ, Emdad L, Sarkar D and
Fisher PB: Astrocyte elevated gene-1 (AEG-1) is a target gene of
oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc.
Proc Natl Acad Sci USA. 103:pp. 17390–17395. 2006; View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Emdad L, Das SK, Dasgupta S, Hu B, Sarkar
D and Fisher PB: AEG-1/MTDH/LYRIC: Signaling pathways, downstream
genes, interacting proteins, and regulation of tumor angiogenesis.
Adv Cancer Res. 120:75–111. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Mottet D, Dumont V, Deccache Y, Demazy C,
Ninane N, Raes M and Michiels C: Regulation of hypoxia-inducible
factor-1alpha protein level during hypoxic conditions by the
phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta
pathway in HepG2 cells. J Biol Chem. 278:31277–31285. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Rius J, Guma M, Schachtrup C, Akassoglou
K, Zinkernagel AS, Nizet V, Johnson RS, Haddad GG and Karin M:
NF-kappaB links innate immunity to the hypoxic response through
transcriptional regulation of HIF-1alpha. Nature. 453:807–811.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Yang MH, Wu MZ, Chiou SH, Chen PM, Chang
SY, Liu CJ, Teng SC and Wu KJ: Direct regulation of TWIST by
HIF-1alpha promotes metastasis. Nat Cell Biol. 10:295–305. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Liang Y, Hu J, Li J, Liu Y, Yu J, Zhuang
X, Mu L, Kong X, Hong D, Yang Q, et al: Epigenetic activation of
TWIST1 by MTDH promotes cancer stem-like cell traits in breast
cancer. Cancer Res. 75:3672–3680. 2015. View Article : Google Scholar : PubMed/NCBI
|
