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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2025 Volume 67 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

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Therapeutic potentials of plant‑based antioxidants on colorectal cancer: Challenges and perspectives (Review)

Daan Fu, Haoyu Fu, Yafeng Wang, Kai Yang, Bingqing Nie, Xiaohuan Lu
Article Number: 107
Published online on: 14 October 2025

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Expression of Concern Open Access

[Expression of Concern] Halofuginone induces the apoptosis of breast cancer cells and inhibits migration via downregulation of matrix metalloproteinase‑9

Mei Ling Jin, Sun Young Park, Young Hun Kim, Geuntae Park, Sang Joon Lee
Article Number: 106
Published online on: 13 October 2025

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Epithelial‑mesenchymal plasticity and cisplatin resistance in germ cell tumors: Mechanisms and emerging therapeutic strategies (Review)

Eleni Solange De Brito Gomes, Tainá Miotto De Souza, Ana Laura Paiva Oliveira, Ana Flavia Souza Peres Bezerra, Ingridy Izabella Vieira Cardoso, Lenilson Silva, Luiz Fernando Lopes, Marcela Nunes Rosa, Mariana Tomazini Pinto
Article Number: 105
Published online on: 13 October 2025

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RHOT1‑mediated molecular mechanism of mitochondrial dysfunction and its phenotypic effects on gastric cancer cells

Yanqi Peng, Xiaoming Chen, Fanhao Kong, Jiayi Zhu, Siwen Yang, Ronghua Fan, Ji Wu, Yanyu Peng
Article Number: 104
Published online on: 09 October 2025

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Emerging insights into alternative end‑joining: Mechanisms, genome instability and therapeutic opportunities in cancer (Review)

Nasir Azam, Xiangyu Liu, Xinghan Li, Lin Ma, Qi Liu
Article Number: 103
Published online on: 09 October 2025

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Expression of Concern Open Access

[Expression of Concern] miR‑221/222 promote malignant progression of glioma through activation of the Akt pathway

Junxia Zhang, Lei Han, Youlin Ge, Xuan Zhou, Anling Zhang, Chunzhi Zhang, Yue Zhong, Yongping You, Eiyu Pu, Chunsheng Kang
Article Number: 102
Published online on: 09 October 2025

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Exosomal microRNAs: A new role in the diagnosis and treatment of lung cancer metastases (Review)

Xin Li, Jian Wang, Weipeng Ge, Xinbo Chen
Article Number: 101
Published online on: 08 October 2025

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Adipocyte‑derived extracellular vesicles sustain mitochondrial metabolism in breast cancer cells: New insights into the cross‑talk between cancer cells and the tumor microenvironment

Luca Gelsomino, Piercarlo Del Console, Maria Stella Murfuni, Marco Gaspari, Francesca Giordano, Giuseppina Daniela Naimo, Marco Fiorillo, Grazia Arpino, Mario Giuliano, Salvatore Panza, Daniela Bonofiglio, Sebastiano Andò, Ines Barone, Cinzia Giordano, Stefania Catalano
Article Number: 100
Published online on: 06 October 2025

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Expression of Concern Open Access

[Expression of Concern] Podoplanin‑mediated TGF‑β‑induced epithelial-mesen­chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 99
Published online on: 25 September 2025

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Application of cfDNA methylation in cancer prognostic assessment: Progress and challenges (Review)

Chenxi Su, Jiaqi Wu, Liping Jiang, Tongtong Lv, Wenxi Liu, Jintong Zhang, Yanhua Zhang, Xiaochun Peng, Jie Tan
Article Number: 98
Published online on: 24 September 2025

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ZBTB20 promotes ferroptosis through inhibiting TMEM109 expression in glioblastoma cells

Xuhao Chen, Mingqi Luo, Xiaoyu Niu, Wang Wang, Huanhuan Cao, Liwei Zhang, Ruolun Wei, Ping Duan
Article Number: 97
Published online on: 24 September 2025

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Expression of Concern Open Access

[Expression of Concern] miR‑135b, upregulated in breast cancer, promotes cell growth and disrupts the cell cycle by regulating LATS2

Kaiyao Hua, Jiali Jin, Junyong Zhao, Jialu Song, Hongming Song, Dengfeng Li, Niraj Maskey, Bingkun Zhao, Chenyang Wu, Hui Xu, Lin Fang
Article Number: 96
Published online on: 15 September 2025

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Review Open Access

From chemotherapy to biological therapy: A review of novel concepts to reduce the side effects of systemic cancer treatment (Review)

Volker Schirrmacher

Pages: 407-419
Published online on: 10 December 2018
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Triple‑negative breast cancer therapy: Current and future perspectives (Review)

Kwang‑Ai Won, Charles Spruck

Pages: 1245-1261
Published online on: 16 October 2020
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Canonical and non-canonical WNT signaling in cancer stem cells and their niches: Cellular heterogeneity, omics reprogramming, targeted therapy and tumor plasticity (Review)

Masaru Katoh

Pages: 1357-1369
Published online on: 19 September 2017
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Anticancer peptide: Physicochemical property, functional aspect and trend in clinical application (Review)

Wararat Chiangjong, Somchai Chutipongtanate, Suradej Hongeng

Pages: 678-696
Published online on: 10 July 2020
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Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review)

George Mihai Nitulescu, Denisa Margina, Petras Juzenas, Qian Peng, Octavian Tudorel Olaru, Emmanouil Saloustros, Concettina Fenga, Demetrios Α. Spandidos, Massimo Libra, Aristidis M. Tsatsakis

Pages: 869-885
Published online on: 24 December 2015
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Circulating microRNAs: New biomarkers in diagnosis, prognosis and treatment of cancer (Review)

Alessandro Allegra, Andrea Alonci, Salvatore Campo, Giuseppa Penna, Annamaria Petrungaro, Demetrio Gerace, Caterina Musolino

Pages: 1897-1912
Published online on: 01 October 2012
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The IL-6/JAK/STAT3 pathway: Potential therapeutic strategies in treating colorectal cancer (Review)

Shu-Wei Wang, Yue-Ming Sun

Pages: 1032-1040
Published online on: 15 January 2014
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The EGFR pathway is involved in the regulation of PD-L1 expression via the IL-6/JAK/STAT3 signaling pathway in EGFR-mutated non-small cell lung cancer

Nan Zhang, Yuanyuan Zeng, Wenwen Du, Jianjie Zhu, Dan Shen, Zeyi Liu, Jian-An Huang

Pages: 1360-1368
Published online on: 26 July 2016
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Article

Phase II studies of polymer-doxorubicin (PK1, FCE28068) in the treatment of breast, lung and colorectal cancer

Leonard W. Seymour, David R. Ferry, David J. Kerr, Daniel Rea, Maggie Whitlock, Richard Poyner, Christopher Boivin, Stuart Hesslewood, Christopher Twelves, Robert Blackie, Andreas Schatzlein, Duncan Jodrell, Donald Bissett, Hilary Calvert, Mike Lind, Adele Robbins, Sally Burtles, Ruth Duncan, James Cassidy

Pages: 1629-1636
Published online on: 01 June 2009
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JAK/STAT3 signaling is required for TGF-β-induced epithelial-mesenchymal transition in lung cancer cells

Reng-Yun Liu, Yuanyuan Zeng, Zhe Lei, Longqiang Wang, Haiping Yang, Zeyi Liu, Jun Zhao, Hong-Tao Zhang

Pages: 1643-1651
Published online on: 21 February 2014
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Article

Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines

Nesstor Pilco-Ferreto, Gloria M. Calaf

Pages: 753-762
Published online on: 03 June 2016
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Review

Update on Epstein-Barr virus and gastric cancer (Review)

Aya Shinozaki-Ushiku, Akiko Kunita, Masashi Fukayama

Pages: 1421-1434
Published online on: 28 January 2015
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Article Open Access

ERGO: A pilot study of ketogenic diet in recurrent glioblastoma Erratum in /ijo/45/6/2605

Johannes Rieger, Oliver Bähr, Gabriele D. Maurer, Elke Hattingen, Kea Franz, Daniel Brucker, Stefan Walenta, Ulrike Kämmerer, Johannes F. Coy, Michael Weller, Joachim P. Steinbach

Pages: 1843-1852
Published online on: 11 April 2014
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Review

HSP27, 70 and 90, anti-apoptotic proteins, in clinical cancer therapy (Review)

Xiaoxia Wang, Meijuan Chen, Jing Zhou, Xu Zhang

Pages: 18-30
Published online on: 25 April 2014
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Cutaneous melanoma: From pathogenesis to therapy (Review)

Giulia C. Leonardi, Luca Falzone, Rossella Salemi, Antonino Zanghì, Demetrios A. Spandidos, James A. Mccubrey, Saverio Candido, Massimo Libra

Pages: 1071-1080
Published online on: 27 February 2018
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Mechanisms and management of 3rd‑generation EGFR‑TKI resistance in advanced non‑small cell lung cancer (Review)

Jingyi He, Zhengrong Huang, Linzhi Han, Yan Gong, Conghua Xie

Article Number: 90
Published online on: 24 September 2021
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Review Open Access

Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: Νew trends in the development of miRNA therapeutic strategies in oncology (Review)

Roberto Gambari, Eleonora Brognara, Demetrios A. Spandidos, Enrica Fabbri

Pages: 5-32
Published online on: 04 May 2016
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Article

Macrophage-secreted IL-8 induces epithelial-mesenchymal transition in hepatocellular carcinoma cells by activating the JAK2/STAT3/Snail pathway Corrigendum in /10.3892/ijo.2024.5672

Xiu-Tao Fu, Zhi Dai, Kang Song, Zhuo-Jun Zhang, Zheng-Jun Zhou, Shao-Lai Zhou, Yi-Ming Zhao, Yong-Sheng Xiao, Qi-Man Sun, Zhen-Bin Ding, Jia Fan

Pages: 587-596
Published online on: 18 November 2014
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Article

Long non-coding RNA HOTAIR promotes tumor cell invasion and metastasis by recruiting EZH2 and repressing E-cadherin in oral squamous cell carcinoma

Yansheng Wu, Li Zhang, Lun Zhang, Yang Wang, Hui Li, Xiubao Ren, Feng Wei, Wenwen Yu, Ting Liu, Xudong Wang, Xuan Zhou, Jinpu Yu, Xishan Hao

Pages: 2586-2594
Published online on: 22 April 2015
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Review

The fusion of two worlds: Non-coding RNAs and extracellular vesicles - diagnostic and therapeutic implications (Review)

Yukie Sato-Kuwabara, Sonia A. Melo, Fernando A. Soares, George A. Calin

Pages: 17-27
Published online on: 17 October 2014
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