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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Article Number: 55
Published online on: 09 March 2026

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Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review)

Guirui Zhang, Yongmo Wu, Mingzhen Wei, Shupeng Huang, Qinghao Wang, Zhengyi Xie, Sisi Liu, Jin Wang
Article Number: 54
Published online on: 06 March 2026

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Retraction Open Access

[Retracted] Design, synthesis and preclinical evaluation of NRC‑AN‑019

Kompella Amala, A.k.S. Bhujanga Rao, Bharathi Gorantla, Christopher S.  Gondi, Jasti S. Rao
Article Number: 53
Published online on: 04 March 2026

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Article Open Access

FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma

Nawal Merjaneh, Ying-Wei Lan, Zicheng Deng, Johnny Donovan, Guolun Wang, Jonathan Do, Tiffany Juan, Xiaomei Xia, Vladimir V. Kalinichenko, Tanya V. Kalin
Article Number: 52
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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Review Open Access

Unleashing the power of urine‑based biomarkers in diagnosis, prognosis and monitoring of bladder cancer (Review)

Xuebin Wan, Dan Wang, Xiaoni Zhang, Mingyan Xu, Yuying Huang, Wenjian Qin, Shifu Chen

Article Number: 18
Published online on: 06 February 2025
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Regulatory networks of HIFs in tumor‑infiltrating immune cells: From molecular mechanisms to therapeutic implications (Review)

Chaoqun Li, Chenge Qin, Xingchen Li, Jinzhu Wang, Yang Li, Qin Sun

Article Number: 32
Published online on: 12 January 2026
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mRNA vaccine development and applications: A special focus on tumors (Review)

Bangjie Chen, Yipin Yang, Xinyi Wang, Wenzhi Yang, You Lu, Daoyue Wang, Enba Zhuo, Yanchao Tang, Junhong Su, Guozheng Tang, Song Shao, Kangsheng Gu

Article Number: 81
Published online on: 09 July 2024
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Review

Circulating microRNAs: New biomarkers in diagnosis, prognosis and treatment of cancer (Review)

Alessandro Allegra, Andrea Alonci, Salvatore Campo, Giuseppa Penna, Annamaria Petrungaro, Demetrio Gerace, Caterina Musolino

Pages: 1897-1912
Published online on: 01 October 2012
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Review Open Access

Role of stress in the pathogenesis of cancer (Review)

Ioannis G. Lempesis, Vasiliki Epameinondas Georgakopoulou, Petros Papalexis, Georgios P. Chrousos, Demetrios A. Spandidos

Article Number: 124
Published online on: 11 September 2023
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Article Open Access

New drugs are not enough‑drug repositioning in oncology: An update

Romina Gabriela Armando, Diego Luis Mengual Gómez, Daniel Eduardo Gomez

Pages: 651-684
Published online on: 20 January 2020
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Triple‑negative breast cancer therapy: Current and future perspectives (Review)

Kwang‑Ai Won, Charles Spruck

Pages: 1245-1261
Published online on: 16 October 2020
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Melatonin and vitamin D as potential synergistic adjuvants for cancer therapy (Review)

Russel J. Reiter, Luiz Gustavo De Almeida Chuffa, Vinícius Augusto Simão, Virna Margarita Martín Giménez, Natalia De Las Heras, Demetrios A. Spandidos, Walter Manucha

Article Number: 114
Published online on: 22 October 2024
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Mechanisms and management of 3rd‑generation EGFR‑TKI resistance in advanced non‑small cell lung cancer (Review)

Jingyi He, Zhengrong Huang, Linzhi Han, Yan Gong, Conghua Xie

Article Number: 90
Published online on: 24 September 2021
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Role of the Wnt signaling pathway in the complex microenvironment of breast cancer and prospects for therapeutic potential (Review)

Meng Xuan Sun, Han Ci Zhu, Yang Yu, Yan Yao, Hua Yao Li, Fu Bin Feng, Qing Yang Wang, Rui Juan Liu, Chang Gang Sun

Article Number: 36
Published online on: 21 March 2025
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Butyrate as a promising therapeutic target in cancer: From pathogenesis to clinic (Review)

Jinzhe Sun, Shiqian Chen, Dan Zang, Hetian Sun, Yan Sun, Jun Chen

Article Number: 44
Published online on: 29 February 2024
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Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu

Article Number: 42
Published online on: 12 February 2026
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Article Open Access

<em>SHARPIN</em> is a novel gene of colorectal cancer that promotes tumor growth potentially via inhibition of p53 expression

Yusuke Nakano, Takaaki Masuda, Takeharu Sakamoto, Noritaka Tanaka, Taro Tobo, Masahiro Hashimoto, Takanari Tatsumi, Hideyuki Saito, Junichi Takahashi, Kensuke Koike, Tadashi Abe, Yuki Ando, Yuki Ozato, Kiyotaka Hosoda, Kosuke Hirose, Satoshi Higuchi, Tomohiko Ikehara, Yuichi Hisamatsu, Takeo Toshima, Yusuke Yonemura, Takayuki Ogino, Mamoru Uemura, Hidetoshi Eguchi, Yuichiro Doki, Koshi Mimori

Article Number: 113
Published online on: 21 October 2024
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From chemotherapy to biological therapy: A review of novel concepts to reduce the side effects of systemic cancer treatment (Review)

Volker Schirrmacher

Pages: 407-419
Published online on: 10 December 2018
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Canonical and non-canonical WNT signaling in cancer stem cells and their niches: Cellular heterogeneity, omics reprogramming, targeted therapy and tumor plasticity (Review)

Masaru Katoh

Pages: 1357-1369
Published online on: 19 September 2017
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Strategies for neoantigen screening and immunogenicity validation in cancer immunotherapy (Review)

Hua Feng, Yuanting Jin, Bin Wu

Article Number: 43
Published online on: 07 May 2025
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The Akt pathway in oncology therapy and beyond (Review)

George Mihai Nitulescu, Maryna Van De Venter, Georgiana Nitulescu, Anca Ungurianu, Petras Juzenas, Qian Peng, Octavian Tudorel Olaru, Daniela Grădinaru, Aristides Tsatsakis, Dimitris Tsoukalas, Demetrios A. Spandidos, Denisa Margina

Pages: 2319-2331
Published online on: 16 October 2018
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Targeting tumor‑associated macrophages: Critical players in tumor progression and therapeutic strategies (Review)

Pengfei Su, Ou Li, Kun Ke, Zhichen Jiang, Jianzhang Wu, Yuanyu Wang, Yiping Mou, Weiwei Jin

Article Number: 60
Published online on: 30 April 2024
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Human‑made electromagnetic fields: Ion forced‑oscillation and voltage‑gated ion channel dysfunction, oxidative stress and DNA damage (Review)

Dimitris J. Panagopoulos, Andreas Karabarbounis, Igor Yakymenko, George P. Chrousos

Article Number: 92
Published online on: 06 October 2021
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Review

Role of DLC1 tumor suppressor gene and MYC oncogene in pathogenesis of human hepatocellular carcinoma: Potential prospects for combined targeted therapeutics (Review)

Drazen B. Zimonjic, Nicholas C. Popescu

Pages: 393-406
Published online on: 10 May 2012
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