Journal Articles

The one-carbon metabolism pathway highlights therapeutic targets for gastrointestinal cancer (Review)

Masamitsu Konno, Ayumu Asai, Koichi Kawamoto, Naohiro Nishida, Taroh Satoh, Yuichiro Doki, Masaki Mori, Hideshi Ishii

Pages: 1057-1063 Published online on: 20 February 2017
Open Access

Apoptosis is augmented in high-grade serous ovarian cancer by the combined inhibition of Bcl-2/Bcl-xL and PARP

Takuhei Yokoyama, Elise C. Kohn, Ethan Brill, Jung-Min Lee

Pages: 1064-1074 Published online on: 15 March 2017
Open Access

A liquid biopsy-based method for the detection and quantification of circulating tumor cells in surgical osteosarcoma patients

Haoqiang Zhang, Peng Gao, Xin Xiao, Michal Heger, Lei Geng, Bo Fan, Yulin Yuan, Chen Huang, Guojing Chen, Yao Liu, Yongchen Hu, Xiuchun Yu, Sujia Wu, Ling Wang, Zhen Wang

Pages: 1075-1086 Published online on: 08 March 2017
Open Access

Overexpression of miRNA-221 promotes cell proliferation by targeting the apoptotic protease activating factor-1 and indicates a poor prognosis in ovarian cancer

Jie Li, Qiang Li, He Huang, Yinguang Li, Li Li, Wenhui Hou, Zeshan You

Pages: 1087-1096 Published online on: 07 March 2017
Open Access

miR‑150 inhibits proliferation and tumorigenicity via retarding G1/S phase transition in nasopharyngeal carcinoma

Xiangyong Li, Fumei Liu, Bihua Lin, Haiqing Luo, Meilian Liu, Jinhua Wu, Caihong Li, Ronggang Li, Xin Zhang, Keyuan Zhou, Dong Ren

Pages: 1097-1108 Published online on: 10 March 2017
Open Access

miR-21 and KLF4 jointly augment epithelial‑mesenchymal transition via the Akt/ERK1/2 pathway

Chen-Hai Liu, Qiang Huang, Zhi-Yuan Jin, Cheng-Lin Zhu, Zhen Liu, Chao Wang

Pages: 1109-1115 Published online on: 14 February 2017
Open Access

UBE2C induces EMT through Wnt/β‑catenin and PI3K/Akt signaling pathways by regulating phosphorylation levels of Aurora-A

Rui Wang, Yue Song, Xi Liu, Qixue Wang, Yunfei Wang, Liwei Li, Chunsheng Kang, Qingyu Zhang

Pages: 1116-1126 Published online on: 17 February 2017
Open Access

Dual roles of protein tyrosine phosphatase kappa in coordinating angiogenesis induced by pro-angiogenic factors

Ping-Hui Sun, Gang Chen, Malcolm Mason, Wen G. Jiang, Lin Ye

Pages: 1127-1135 Published online on: 20 February 2017
Open Access

Deubiquitinating enzyme USP20 is a positive regulator of Claspin and suppresses the malignant characteristics of gastric cancer cells

Chao Wang, Chen Yang, Jun Ji, Jinling Jiang, Min Shi, Qu Cai, Yingyan Yu, Zhenggang Zhu, Jun Zhang

Pages: 1136-1146 Published online on: 08 March 2017
Open Access

Gene expression profiling in bladder cancer identifies potential therapeutic targets

Syed A. Hussain, Daniel H. Palmer, Wing-Kin Syn, Joseph J. Sacco, Richard M.D. Greensmith, Taha Elmetwali, Vijay Aachi, Bryony H. Lloyd, Puthen V. Jithesh, John Arrand, Darren Barton, Jawaher Ansari, D. Ross Sibson, Nicholas D. James

Pages: 1147-1159 Published online on: 02 March 2017
Open Access

N-terminal polypeptide derived from vMIP-II exerts its antitumor activity by inhibiting the CXCR4 pathway in human glioma

Qingling Yang, Haihua Wu, Haifeng Wang, Yu Li, Lingyu Zhang, Lihua Zhu, Wenrui Wang, Jihong Zhou, Yingxiao Fu, Sulian Chen, Qiong Wu, Changjie Chen, Congzhao Zhou

Pages: 1160-1174 Published online on: 08 March 2017
Open Access

Design, synthesis and pharmaco-toxicological assessment of 5-mercapto-1,2,4-triazole derivatives with antibacterial and antiproliferative activity

Marius Mioc, Codruta Soica, Vasile Bercean, Sorin Avram, Mihaela Balan‑Porcarasu, Dorina Coricovac, Roxana Ghiulai, Delia Muntean, Florina Andrica, Cristina Dehelean, Demetrios A. Spandidos, Aristides M. Tsatsakis, Ludovic Kurunczi

Pages: 1175-1183 Published online on: 14 March 2017

High stathmin 1 expression is associated with poor prognosis and chemoradiation resistance in esophageal squamous cell carcinoma

Shigemasa Suzuki, Takehiko Yokobori, Bolag Altan, Keigo Hara, Daigo Ozawa, Naritaka Tanaka, Makoto Sakai, Akihiko Sano, Makoto Sohda, Halin Bao, Minoru Fukuchi, Tatsuya Miyazaki, Kyoichi Kaira, Takayuki Asao, Hiroyuki Kuwano

Pages: 1184-1190 Published online on: 07 March 2017

Inflammatory peroxidases promote breast cancer progression in mice via regulation of the tumour microenvironment

Vasilios Panagopoulos, Damien A. Leach, Irene Zinonos, Vladimir Ponomarev, Giovanni Licari, Vasilios Liapis, Wendy V. Ingman, Peter Anderson, Mark O. DeNichilo, Andreas Evdokiou

Pages: 1191-1200 Published online on: 20 February 2017

Enhanced expression of α2,3-linked sialic acids promotes gastric cancer cell metastasis and correlates with poor prognosis

Li Shen, Zhiguo Luo, Junbo Wu, Li Qiu, Ming Luo, Qing Ke, Xiaoxia Dong

Pages: 1201-1210 Published online on: 20 February 2017

miR-940 upregulation contributes to human cervical cancer progression through p27 and PTEN inhibition

Ke Su, Chun-Fang Wang, Ying Zhang, Yu-Jie Cai, Yan-Yan Zhang, Qian Zhao

Pages: 1211-1220 Published online on: 07 March 2017

Rb deficiency accelerates progression of carcinoma of the urinary bladder in vivo and in vitro through inhibiting autophagy and apoptosis

Cheng-Yuan Wang, Zhi-Bin Xu, Jiang-Ping Wang, Yong Jiao, Bo Zhang

Pages: 1221-1232 Published online on: 22 February 2017

HCRP1 inhibits TGF-β induced epithelial-mesenchymal transition in hepatocellular carcinoma

Wenlin Yang, Ji-Gang Wang, Jiawen Xu, Danmei Zhou, Kehan Ren, Chenjian Hou, Linlin Chen, Xiuping Liu

Pages: 1233-1240 Published online on: 08 March 2017

Silencing of FANCD2 enhances the radiosensitivity of metastatic cervical lymph node-derived head and neck squamous cell carcinoma HSC-4 cells

Hua-Jun Feng, Yi-Lin Bao, Zhuo-Ping Liang, Fei-Peng Zhao, Sheng-En Xu, Wei Xu, Chong Zhao, Gang Qin

Pages: 1241-1250 Published online on: 07 March 2017

Silencing Snail suppresses tumor cell proliferation and invasion by reversing epithelial-to-mesenchymal transition and arresting G2/M phase in non-small cell lung cancer

Xueying Yang, Mengmeng Han, Haibo Han, Bingjing Wang, Sheng Li, Zhiqian Zhang, Wei Zhao

Pages: 1251-1260 Published online on: 21 February 2017

The nerve growth factor alters calreticulin translocation from the endoplasmic reticulum to the cell surface and its signaling pathway in epithelial ovarian cancer cells

Carolina Andrea Vera, Lorena Oróstica, Fernando Gabler, Arturo Ferreira, Alberto Selman, Margarita Vega, Carmen Aurora Romero

Pages: 1261-1270 Published online on: 28 February 2017

HOTAIR upregulates an 18-gene cell cycle-related mRNA network in glioma

Kai Huang, Jia Sun, Chao Yang, Yunfei Wang, Bingcong Zhou, Chunsheng Kang, Lei Han, Qixue Wang

Pages: 1271-1278 Published online on: 07 March 2017

Selective FGFR inhibitor BGJ398 inhibits phosphorylation of AKT and STAT3 and induces cytotoxicity in sphere-cultured ovarian cancer cells

Hwa Jun Cha, Jung Hye Choi, In Chul Park, Chun Ho Kim, Sung Kwan An, Tae Jin Kim, Jae Ho Lee

Pages: 1279-1288 Published online on: 15 March 2017

Molecular mechanism of C-reaction protein in promoting migration and invasion of hepatocellular carcinoma cells in vitro

Shasha Shen, Jiaojiao Gong, Yixuan Yang, Si Qin, Lifan Huang, Sha She, Min Yang, Hong Ren, Huaidong Hu

Pages: 1289-1298 Published online on: 13 March 2017

Quercetin nanoparticles display antitumor activity via proliferation inhibition and apoptosis induction in liver cancer cells

Ke-Wei Ren, Ya-Hua Li, Gang Wu, Jian-Zhuang Ren, Hui-Bin Lu, Zong-Ming Li, Xin-Wei Han

Pages: 1299-1311 Published online on: 20 February 2017

Ectopic expression of the ATP synthase β subunit on the membrane of PC-3M cells supports its potential role in prostate cancer metastasis

Wei Li, Yulin Li, Gaiyun Li, Zilong Zhou, Xiaona Chang, Yang Xia, Xinjie Dong, Zhijing Liu, Bo Ren, Wei Liu, Yilei Li

Pages: 1312-1320 Published online on: 16 February 2017

Curcumin reverses benzidine-induced epithelial-mesenchymal transition via suppression of ERK5/AP-1 in SV-40 immortalized human urothelial cells

Zhiqi Liu, Jie Liu, Li Zhao, Hao Geng, Jiaxing Ma, Zhiqiang Zhang, Dexin Yu, Caiyun Zhong

Pages: 1321-1329 Published online on: 21 February 2017

Ursolic acid nanoparticles inhibit cervical cancer growth in vitro and in vivo via apoptosis induction

Shaoguang Wang, Xiaomei Meng, Yaozhong Dong

Pages: 1330-1340 Published online on: 22 February 2017

Suppression of cancer stem-like phenotypes in NCI-H460 lung cancer cells by vanillin through an Akt-dependent pathway

Songpol Srinual, Pithi Chanvorachote, Varisa Pongrakhananon

Pages: 1341-1351 Published online on: 17 February 2017

Furin promotes epithelial-mesenchymal transition in pancreatic cancer cells via Hippo-YAP pathway

Youli Zhang, Meng Zhou, Hong Wei, Hailang Zhou, Junbo He, Ying Lu, Dawei Wang, Baoding Chen, Jian Zeng, Wanxin Peng, Fengyi Du, Aihua Gong, Min Xu

Pages: 1352-1362 Published online on: 02 March 2017

All-trans retinoic acid restored the osteogenic ability of BMP9 in osteosarcoma through the p38 MAPK pathway

Nian Wu, Ruidong Li, Zijun Meng, Mao Nie, Qianzhao Chen, Baicheng He, Zhongliang Deng, Liangjun Yin

Pages: 1363-1371 Published online on: 13 March 2017

SF-KDM2A binds to ribosomal RNA gene promoter, reduces H4K20me3 level, and elevates ribosomal RNA transcription in breast cancer cells

Kengo Okamoto, Yuji Tanaka, Makoto Tsuneoka

Pages: 1372-1382 Published online on: 10 March 2017

miR-28-5p promotes the development and progression of ovarian cancer through inhibition of N4BP1

Juan Xu, Nan Jiang, Haijuan Shi, Shanshan Zhao, Shuzhong Yao, Huimin Shen

Pages: 1383-1391 Published online on: 16 March 2017

3-Hydroxyterphenyllin, a natural fungal metabolite, induces apoptosis and S phase arrest in human ovarian carcinoma cells

Yaomin Wang, Casey Compton, Gary O. Rankin, Stephen J. Cutler, Yon Rojanasakul, Youying Tu, Yi Charlie Chen

Pages: 1392-1402 Published online on: 02 March 2017

Inhibin-α gene mutations and mRNA levels in human lymphoid and myeloid leukemia cells

Young Il Kim, Seung-Won Park, Hye Shin Kwon, Hyung-Seok Yang, Sun Young Cho, Young Jin Kim, Hee Joo Lee

Pages: 1403-1412 Published online on: 02 March 2017

Expression and prognostic value of the cell polarity PAR complex members in thyroid cancer

Chiara Tuccilli, Enke Baldini, Yannick Arlot-Bonnemains, Frank Chesnel, Salvatore Sorrenti, Corrado De Vito, Eleonora D'Armiento, Alessandro Antonelli, Poupak Fallahi, Sara Watutantrige, Francesco Tartaglia, Susi Barollo, Caterina Mian, Stefano Arcieri, Domenico Mascagni, Daniele Pironi, Marco Bononi, Massimo Vergine, Massimo Monti, Angelo Filippini, Salvatore Ulisse

Pages: 1413-1422 Published online on: 08 March 2017

Effects of irradiation on human leukocyte antigen class I expression in human papillomavirus positive and negative base of tongue and mobile tongue squamous cell carcinoma cell lines

Linnea Haeggblom, Cecilia Nordfors, Nikolaos Tertipis, Cinzia Bersani, Torbjörn Ramqvist, Anders Näsman, Tina Dalianis

Pages: 1423-1430 Published online on: 16 March 2017

Targeting glutamine metabolism and the focal adhesion kinase additively inhibits the mammalian target of the rapamycin pathway in spheroid cancer stem-like properties of ovarian clear cell carcinoma in vitro

Masakazu Sato, Kei Kawana, Katsuyuki Adachi, Asaha Fujimoto, Mitsuyo Yoshida, Hiroe Nakamura, Haruka Nishida, Tomoko Inoue, Ayumi Taguchi, Juri Ogishima, Satoko Eguchi, Aki Yamashita, Kensuke Tomio, Osamu Wada-Hiraike, Katsutoshi Oda, Takeshi Nagamatsu, Yutaka Osuga, Tomoyuki Fujii

Pages: 1431-1438 Published online on: 23 February 2017

Matrix stiffness regulates the proliferation, stemness and chemoresistance of laryngeal squamous cancer cells

Lian Hui, Jingru Zhang, Xiaoxu Ding, Xing Guo, Xuejun Jiang

Pages: 1439-1447 Published online on: 15 February 2017

Therapeutic effects of Schisandra chinensis on the hyperprolactinemia in rat

So-Hye Hong, Mei Li, Eui-Bae Jeung, Geun-Shik Lee, Eui-Ju Hong, Young-Whan Choi, Beum-Soo An

Pages: 1448-1454 Published online on: 17 February 2017
Open Access

[Corrigendum] Promoter methylation of RASSF1A modulates the effect of the microtubule-targeting agent docetaxel in breast cancer

Eun Young Gil, Uk Hyun Jo, Hoiseon Jeong, Young Mi Whang, Ok Hee Woo, Kyu Ran Cho, Jae Hong Seo, Aeree Kim, Eun Sook Lee, Insong Koh, Yeul Hong Kim, Kyong Hwa Park

Pages: 1455-1455 Published online on: 07 March 2017
Journal Cover

Cover Legend PDF

April 2017
Volume 50 Issue 4

Print ISSN: 1019-6439
Online ISSN: 1791-2423

2015 Impact Factor: 3.018
Ranked #30/211 Oncology
(total number of cites)

Sign up for eToc alerts

Recommend to Library

Full Size Image