Journal Articles

Hostile takeover: Manipulation of HIF-1 signaling in pathogen-associated cancers (Review)

Caixia Zhu, Qing Zhu, Chong Wang, Liming Zhang, Fang Wei, Qiliang Cai

Pages: 1269-1276 Published online on: 27 July 2016
Open Access

Dexamethasone downregulates expression of carbonic anhydrase IX via HIF-1α and NF-κB-dependent mechanisms

Veronika Simko, Martina Takacova, Michaela Debreova, Katarina Laposova, Elena Ondriskova-Panisova, Silvia Pastorekova, Lucia Csaderova, Jaromir Pastorek

Pages: 1277-1288 Published online on: 14 July 2016
Open Access

XIAP inhibits mature Smac-induced apoptosis by degrading it through ubiquitination in NSCLC

Sida Qin, Chengcheng Yang, Boxiang Zhang, Xiang Li, Xin Sun, Gang Li, Jing Zhang, Guodong Xiao, Xiao Gao, Guanghong Huang, Peili Wang, Hong Ren

Pages: 1289-1296 Published online on: 27 July 2016
Open Access

Cancer-associated fibroblast suppresses killing activity of natural killer cells through downregulation of poliovirus receptor (PVR/CD155), a ligand of activating NK receptor

Tomoko Inoue, Katsuyuki Adachi, Kei Kawana, Ayumi Taguchi, Takeshi Nagamatsu, Asaha Fujimoto, Kensuke Tomio, Aki Yamashita, Satoko Eguchi, Haruka Nishida, Hiroe Nakamura, Masakazu Sato, Mitsuyo Yoshida, Takahide Arimoto, Osamu Wada-Hiraike, Katsutoshi Oda, Yutaka Osuga, Tomoyuki Fujii

Pages: 1297-1304 Published online on: 26 July 2016

The resveratrol analogue, 3,4,5,4'‑trans-tetramethoxystilbene, inhibits the growth of A375 melanoma cells through multiple anticancer modes of action

Vasilis P. Androutsopoulos, Irene Fragiadaki, Demetrios A. Spandidos, Androniki Tosca

Pages: 1305-1314 Published online on: 28 July 2016
Open Access

Radiofrequency radiation at Stockholm Central Railway Station in Sweden and some medical aspects on public exposure to RF fields

Lennart Hardell, Tarmo Koppel, Michael Carlberg, Mikko Ahonen, Lena Hedendahl

Pages: 1315-1324 Published online on: 12 August 2016
Open Access

RNase activity of sialic acid-binding lectin from bullfrog eggs drives antitumor effect via the activation of p38 MAPK to caspase-3/7 signaling pathway in human breast cancer cells

Yukiko Kariya, Takeo Tatsuta, Shigeki Sugawara, Yoshinobu Kariya, Kazuo Nitta, Masahiro Hosono

Pages: 1334-1342 Published online on: 11 August 2016
Open Access

CD44 correlates with clinicopathological characteristics and is upregulated by EGFR in breast cancer

Hanxiao Xu, Kongju Wu, Yijun Tian, Qian Liu, Na Han, Xun Yuan, Lu Zhang, Gen Sheng Wu, Kongming Wu

Pages: 1343-1350 Published online on: 29 July 2016

Iron depletion-induced downregulation of N-cadherin expression inhibits invasive malignant phenotypes in human esophageal cancer

Seishi Nishitani, Kazuhiro Noma, Toshiaki Ohara, Yasuko Tomono, Shinichiro Watanabe, Hiroshi Tazawa, Yasuhiro Shirakawa, Toshiyoshi Fujiwara

Pages: 1351-1359 Published online on: 29 July 2016

The EGFR pathway is involved in the regulation of PD-L1 expression via the IL-6/JAK/STAT3 signaling pathway in EGFR-mutated non-small cell lung cancer

Nan Zhang, Yuanyuan Zeng, Wenwen Du, Jianjie Zhu, Dan Shen, Zeyi Liu, Jian-An Huang

Pages: 1360-1368 Published online on: 26 July 2016

Increased expression levels of ppGalNAc-T13 in lung cancers: Significance in the prognostic diagnosis

Kenichi Nogimori, Tomoko Hori, Koji Kawaguchi, Takayuki Fukui, Shinji Mii, Hiroshi Nakada, Yasuyuki Matsumoto, Yoshio Yamauchi, Masahide Takahashi, Keiko Furukawa, Okajima Tetsuya, Kohei Yokoi, Yoshinori Hasegawa, Koichi Furukawa

Pages: 1369-1376 Published online on: 29 July 2016

Enhancement of active MMP release and invasive activity of lymph node metastatic tongue cancer cells by elevated signaling via the TNF-α-TNFR1-NF-κB pathway and a possible involvement of angiopoietin-like 4 in lung metastasis

Takuya Tanaka, Takahisa Imamura, Masakazu Yoneda, Atsushi Irie, Hidenao Ogi, Masashi Nagata, Ryoji Yoshida, Daiki Fukuma, Kenta Kawahara, Masanori Shinohara, Hideki Nakayama

Pages: 1377-1384 Published online on: 10 August 2016

Cell division cycle associated 1 as a novel prognostic biomarker and therapeutic target for oral cancer

Phung Manh Thang, Atsushi Takano, Yoshihiro Yoshitake, Masanori Shinohara, Yoshinori Murakami, Yataro Daigo

Pages: 1385-1393 Published online on: 05 August 2016

SPARC overexpression combined with radiation retards angiogenesis by suppressing VEGF-A via miR‑410 in human neuroblastoma cells

Jerusha Boyineni, Smita Tanpure, Manu Gnanamony, Reuben Antony, Karen S. Fernández, Julian Lin, David Pinson, Christopher S. Gondi

Pages: 1394-1406 Published online on: 03 August 2016

AMP-activated protein kinase activator, HL156A reduces thioacetamide-induced liver fibrosis in mice and inhibits the activation of cultured hepatic stellate cells and macrophages

Hye Shin Lee, Hyun-Sang Shin, Jinhyeok Choi, Sung-Jin Bae, Hee-Jun Wee, Taekwon Son, Ji Hae Seo, Ji-Hyeon Park, Sung-Wuk Kim, Kyu-Won Kim

Pages: 1407-1414 Published online on: 21 July 2016

Prognostic value of pigment epithelium-derived factor for neoadjuvant radiation therapy in patients with locally advanced rectal carcinoma

Haizhao Yi, Dengbo Ji, Tiancheng Zhan, Yunfeng Yao, Ming Li, Jinying Jia, Zhaowei Li, Jin Gu

Pages: 1415-1426 Published online on: 12 July 2016

β-Elemene enhances the efficacy of gefitinib on glioblastoma multiforme cells through the inhibition of the EGFR signaling pathway

Lin Mu, Tianjiao Wang, Yanwei Chen, Xinqiang Tang, Yuhui Yuan, Yongshun Zhao

Pages: 1427-1436 Published online on: 21 July 2016

MicroRNA-186 suppresses cell proliferation and metastasis through targeting MAP3K2 in non-small cell lung cancer

Tonghai Huang, Kelin She, Guilin Peng, Wei Wang, Jun Huang, Jingpei Li, Zheng Wang, Jianxing He

Pages: 1437-1444 Published online on: 29 July 2016

α-Lipoic acid sensitizes lung cancer cells to chemotherapeutic agents and anoikis via integrin β1/β3 downregulation

Punyawee Puchsaka, Chatchai Chaotham, Pithi Chanvorachote

Pages: 1445-1456 Published online on: 18 July 2016

The novel model peptide, αAL14, regulates angiogenesis by inhibiting VEGFR 2-mediated signaling in HUVECs

Nan-Hee Kim, Chang-Won Kang, Hye-Jin Go, Chan-Hee Kim, Nam Gyu Park, Gun-Do Kim

Pages: 1457-1468 Published online on: 09 August 2016

Metabotropic glutamate receptor 3 is involved in B-cell-related tumor apoptosis

Xiaoling Liu, Yu Zhang, Zhiding Wang, Xiaoqian Wang, Gaizhi Zhu, Gencheng Han, Guojiang Chen, Chunmei Hou, Tianxiao Wang, Beifen Shen, Yan Li, Ning Ma, He Xiao, Renxi Wang

Pages: 1469-1478 Published online on: 15 July 2016

The resveratrol analog HS-1793 enhances radiosensitivity of mouse-derived breast cancer cells under hypoxic conditions

Yoo Jin Choi, Kyu Heo, Hee Sung Park, Kwang Mo Yang, Min Ho Jeong

Pages: 1479-1488 Published online on: 03 August 2016

Abnormal expression of FOSB correlates with tumor progression and poor survival in patients with gastric cancer

Chong Tang, Yasu Jiang, Weiwei Shao, Wen Shi, Xuesong Gao, Weiyan Qin, Tian Jiang, Feiran Wang, Shichun Feng

Pages: 1489-1496 Published online on: 18 August 2016

Tricin, 4',5,7-trihydroxy-3',5'-dimethoxyflavone, exhibits potent antiangiogenic activity in vitro

Jang Mi Han, Ho Jeong Kwon, Hye Jin Jung

Pages: 1497-1504 Published online on: 03 August 2016

Downregulation of RLIP76 is associated with vincristine resistance in human colorectal cancer HCT-8/VCR cells

Wenwen Wang, Juan Liu, Jianni Qi, Junyong Zhang, Qiang Zhu, Jincai Ma, Chengyong Qin

Pages: 1505-1512 Published online on: 23 August 2016

Inhibitory effect of bufalin combined with Hedgehog signaling pathway inhibitors on proliferation and invasion and metastasis of liver cancer cells

Xia Sheng, Xiaoting Sun, Kang Sun, Hua Sui, Jianmin Qin, Qi Li

Pages: 1513-1524 Published online on: 22 August 2016

Honokiol inhibits migration of renal cell carcinoma through activation of RhoA/ROCK/MLC signaling pathway

Shujie Cheng, Victor Castillo, Matt Welty, Isaac Eliaz, Daniel Sliva

Pages: 1525-1530 Published online on: 19 August 2016

MicroRNA-7 inhibits proliferation, migration and invasion of thyroid papillary cancer cells via targeting CKS2

Kaiyao Hua, Jiali Jin, Huiwen Zhang, Bingkun Zhao, Chenyang Wu, Hui Xu, Lin Fang

Pages: 1531-1540 Published online on: 18 August 2016

Association and regulation of protein factors of field effect in prostate tissues

Kristin N. Gabriel, Anna C. Jones, Julie P.T. Nguyen, Kresta S. Antillon, Sara N. Janos, Heidi N. Overton, Shannon M. Jenkins, Emily H. Frisch, Kristina A. Trujillo, Marco Bisoffi

Pages: 1541-1552 Published online on: 22 August 2016

Effect of resveratrol on cancer progression through the REG Ⅲ expression pathway in head and neck cancer cells

Shinji Mikami, Ichiro Ota, Takashi Masui, Asako Itaya‑Hironaka, Ryogo Shobatake, Hideyuki Okamoto, Shin Takasawa, Tadashi Kitahara

Pages: 1553-1560 Published online on: 19 August 2016

A novel polysaccharide derived from algae extract induces apoptosis and cell cycle arrest in human gastric carcinoma MKN45 cells via ROS/JNK signaling pathway

Peiyu Xie, Isao Fujii, Jien Zhao, Makoto Shinohara, Makoto Matsukura

Pages: 1561-1568 Published online on: 18 August 2016

c-Myc modulates glucose metabolism via regulation of miR-184/PKM2 pathway in clear-cell renal cell carcinoma

Jiwei Huang, Wen Kong, Jin Zhang, Yonghui Chen, Wei Xue, Dongming Liu, Yiran Huang

Pages: 1569-1575 Published online on: 14 July 2016

Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol

Su-Wei Xu, Betty Yuen Kwan Law, Simon Wing Fai Mok, Elaine Lai Han Leung, Xing Xing Fan, Paolo Saul Coghi, Wu Zeng, Chung-Hang Leung, Dik-Lung Ma, Liang Liu, Vincent Kam Wai Wong

Pages: 1576-1588 Published online on: 03 August 2016

Upregulation of microRNA-370 promotes cell apoptosis and inhibits proliferation by targeting PTEN in human gastric cancer

Yang Zeng, Meng Fu, Gang-Wei Wu, An-Zu Zhang, Jin-Ping Chen, Hong-Yue Lin, Yong-An Fu, Jing Jia, Zong-Da Cai, Xiao-Jian Wu, Ping Lan

Pages: 1589-1599 Published online on: 02 August 2016

Deficiency of 53BP1 inhibits the radiosensitivity of colorectal cancer

Yong Xiao, Xiumei Zheng, Ai Huang, Tao Liu, Tao Zhang, Hong Ma

Pages: 1600-1608 Published online on: 25 July 2016

Sulforaphane increases the efficacy of anti-androgens by rapidly decreasing androgen receptor levels in prostate cancer cells

Namrata Khurana, Sudha Talwar, Partha K. Chandra, Pankaj Sharma, Asim B. Abdel-Mageed, Debasis Mondal, Suresh C. Sikka

Pages: 1609-1619 Published online on: 02 August 2016

Transcriptional regulation of E-cadherin by small activating RNA: A new double-stranded RNA

Zhiming Wu, Yan Li, Zhiyong Li, Zhuowei Liu, Zike Qin, Xiangdong Li, Yunlin Ye, Lei Bu, Bin Lin, Zhanyu Wang, Guojin Jia, Gang Chen

Pages: 1620-1628 Published online on: 03 August 2016

miR-449 overexpression inhibits papillary thyroid carcinoma cell growth by targeting RET kinase-β-catenin signaling pathway

Zongyu Li, Xin Huang, Jinkai Xu, Qinghua Su, Jun Zhao, Jiancang Ma

Pages: 1629-1637 Published online on: 18 August 2016

Caudatin targets TNFAIP1/NF-κB and cytochrome c/caspase signaling to suppress tumor progression in human uterine cancer

Zhi-Wen Tan, Shun Xie, Si-Yang Hu, Tao Liao, Pan Liu, Ke-Hong Peng, Xin-Zhou Yang, Zhi-Li He, Hong-Yan Tang, Yuan Cui, Xiao-Ning Peng, Jian Zhang, Chang Zhou

Pages: 1638-1650 Published online on: 19 August 2016

Identification of proteomic and metabolic signatures associated with chemoresistance of human epithelial ovarian cancer

Wenjuan Wu, Qi Wang, Fuqiang Yin, Zhijun Yang, Wei Zhang, Hani Gabra, Li Li

Pages: 1651-1665 Published online on: 10 August 2016

Triiodothyronine regulates cell growth and survival in renal cell cancer

Anna M. Czarnecka, Damian Matak, Lukasz Szymanski, Karolina H. Czarnecka, Slawomir Lewicki, Robert Zdanowski, Ewa Brzezianska-Lasota, Cezary Szczylik

Pages: 1666-1678 Published online on: 23 August 2016

Silencing of CDC20 suppresses metastatic castration-resistant prostate cancer growth and enhances chemosensitivity to docetaxel

Ke Li, Yunhua Mao, Li Lu, Cheng Hu, Dejuan Wang, Jie Si-Tu, Minhua Lu, Shubin Peng, Jianguang Qiu, Xin Gao

Pages: 1679-1685 Published online on: 23 August 2016

Prolonged survival in hepatocarcinoma patients with increased regucalcin gene expression: HepG2 cell proliferation is suppressed by overexpression of regucalcin in vitro

Masayoshi Yamaguchi, Satoru Osuka, M. Neale Weitzmann, Bassel F. El-Rayes, Mamoru Shoji, Tomiyasu Murata

Pages: 1686-1694 Published online on: 23 August 2016

Genome-wide profiling of long non-coding RNA expression patterns in anthracycline-resistant breast cancer cells

Dong-Xu He, Guang-Yuan Zhang, Xiao-Ting Gu, Ai-Qin Mao, Chun-Xiao Lu, Jian Jin, De-Quan Liu, Xin Ma

Pages: 1695-1703 Published online on: 22 August 2016

Tetramethypyrazine inhibits renal cell carcinoma cells through inhibition of NKG2D signaling pathways

Yun Luan, Junli Liu, Xiaoli Liu, Xia Xue, Feng Kong, Chao Sun, Jue Wang, Ling Liu, Hongying Jia

Pages: 1704-1712 Published online on: 23 August 2016

Peridinin, a carotenoid, inhibits proliferation and survival of HTLV-1-infected T-cell lines

Chie Ishikawa, Takahiro Jomori, Junichi Tanaka, Masachika Senba, Naoki Mori

Pages: 1713-1721 Published online on: 04 August 2016

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression

Johnny Rached, Zeina Nasr, Jad Abdallah, Tamara Abou-Antoun

Pages: 1722-1730 Published online on: 18 July 2016

Hypoxia upregulates Malat1 expression through a CaMKK/AMPK/HIF-1α axis

Sandrine Sallé-Lefort, Stéphanie Miard, Marc-André Nolin, Louise Boivin, Marie-Ève Paré, Richard Debigaré, Frédéric Picard

Pages: 1731-1736 Published online on: 25 July 2016

EBP50 interacts with EGFR and regulates EGFR signaling to affect the prognosis of cervical cancer patients

Zhiqiang Peng, Qiqi Wang, Yue Zhang, Junqi He, Junfang Zheng

Pages: 1737-1745 Published online on: 11 August 2016

Fluoxetine regulates cell growth inhibition of interferon-α

Yu-Min Lin, Bu-Chin Yu, Wen-Tai Chiu, Hung-Yu Sun, Yu-Chieh Chien, Hui-Chen Su, Shu-Yang Yen, Hsin-Wen Lai, Chyi-Huey Bai, Kung-Chia Young, Chiung-Wen Tsao

Pages: 1746-1754 Published online on: 05 August 2016
Open Access

Development of a robust DNA quality and quantity assessment qPCR assay for targeted next-generation sequencing library preparation

Jennifer Dang, Pedro Mendez, Sharon Lee, James W. Kim, Jun-Hee Yoon, Thomas W. Kim, Charles J. Sailey, David M. Jablons, Il-Jin Kim

Pages: 1755-1765 Published online on: 11 August 2016
Open Access

[Corrigendum] VEGF in nuclear medicine: Clinical application in cancer and future perspectives (Review)

Samanta Taurone, Filippo Galli, Alberto Signore, Enzo Agostinelli, Rudi A.J.O. Dierckx, Antonio Minni, Marcella Pucci, Marco Artico

Pages: 1766-1766 Published online on: 29 July 2016
Journal Cover

Cover Legend PDF

October 2016
Volume 49 Issue 4

Print ISSN: 1019-6439
Online ISSN: 1791-2423

2015 Impact Factor: 3.018
Ranked #30/211 Oncology
(total number of cites)

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