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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2006 Volume 28 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Enteral (oral or tube administration) nutritional support and eicosapentaenoic acid in patients with cancer: A systematic review

M. Elia, M. A.E. Van Bokhorst-de van der Schueren, J. Garvey, A. Goedhart, K. Lundholm, G. Nitenberg, R. J. Stratton
Pages: 5-23
Published online on: 01 January 2006

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Article

Mcl-1 is an anti-apoptotic factor for human hepatocellular carcinoma

Binje Fleischer, Henning Schulze-Bergkamen, Marcus Schuchmann, Achim Weber, Stefan Biesterfeld, Martina Müller, Peter H. Krammer, Peter R. Galle
Pages: 25-32
Published online on: 01 January 2006

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Article

Increased expression of membrane-type matrix metalloproteinase-1 is correlated with poor prognosis in patients with osteosarcoma

Mitsutoshi Uchibori, Yoshihiro Nishida, Tetsuro Nagasaka, Yoshihisa Yamada, Keisuke Nakanishi, Naoki Ishiguro
Pages: 33-42
Published online on: 01 January 2006

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Article

Activation of telomerase in BeWo cells by estrogen and 2,3,7,8-tetrachlorodibenzo-p-dioxin in co-operation with c-Myc

Poonam Sarkar, Kazuhiro Shiizaki, Junzo Yonemoto, Hideko Sone
Pages: 43-51
Published online on: 01 January 2006

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Article

Combination treatment with temozolomide and thalidomide inhibits tumor growth and angiogenesis in an orthotopic glioma model

Myung Jin Son, Jong-Soo Kim, Mi Hyun Kim, Hyun Seok Song, Ji Tae Kim, Heechul Kim, Taekyun Shin, Hyun Jung Jeon, Dong-Sup Lee, Shi-Young Park, Yung-Jin Kim, Jong-Hyun Kim, Do-Hyun Nam
Pages: 53-59
Published online on: 01 January 2006

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Article

CXCR4 expression is associated with lymph-node metastasis of oral squamous cell carcinoma

Tohru Ishikawa, Koh-Ichi Nakashiro, Shingo Hara, Sebastian K. Klosek, Chunnan Li, Satoru Shintani, Hiroyuki Hamakawa
Pages: 61-66
Published online on: 01 January 2006

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Article

Expression patterns among interferon regulatory factor-1, human X-box binding protein-1, nuclear factor kappa B, nucleophosmin, estrogen receptor-alpha and progesterone receptor proteins in breast cancer tissue microarrays

Yuelin Zhu, Baljit Singh, Stephen Hewitt, Aiyi Liu, Bianca Gomez, Antai Wang, Robert Clarke
Pages: 67-76
Published online on: 01 January 2006

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Article

Expression of vascular cell adhesion molecule-1 (CD 106) in normal and neoplastic human esophageal squamous epithelium

Jan Heidemann, Christian Maaser, Andreas Lügering, Thomas W. Spahn, Klaus P. Zimmer, Hermann Herbst, Parvaneh Rafiee, Wolfram Domschke, Christian F. Krieglstein, David G. Binion, Torsten F. Kucharzik
Pages: 77-85
Published online on: 01 January 2006

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Article

Growth factor biomarkers associated with estrogen- and radiation-induced breast cancer progression

G. M. Calaf, D. Roy, T. K. Hei
Pages: 87-93
Published online on: 01 January 2006

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Article

Differential expression of trypsinogen and tumor-associated trypsin inhibitor (TATI) in bladder cancer

K. Hotakainen, A. Bjartell, A. Sankila, R. Järvinen, A. Paju, E. Rintala, C. Haglund, U.-H. Stenman
Pages: 95-101
Published online on: 01 January 2006

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Article

From tissue phenotype to proteotype: Sensitive protein identification in microdissected tumor tissue

Zhengping Zhuang, Steve Huang, Jeff A. Kowalak, Ying Shi, Jingqi Lei, Makoto Furuta, Youn-Soo Lee, Irina A. Lubensky, Griffin P. Rodgers, Albert S. Cornelius, Robert J. Weil, Bin T. Teh, Alexander O. Vortmeyer
Pages: 103-110
Published online on: 01 January 2006

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Article

Increased cell compaction can augment the resistance of HT-29 human colon adenocarcinoma spheroids to ionizing radiation

Antonella Ferrante, Gabriella Rainaldi, Paola Indovina, Pietro Luigi Indovina, Maria Teresa Santini
Pages: 111-118
Published online on: 01 January 2006

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Article

Induction of p53-mediated apoptosis and recovery of chemosensitivity through p53 transduction in human glioblastoma cells by cisplatin

Chang-Min Park, Myung-Jin Park, Hee-Jin Kwak, Sang-Ik Moon, Doo-Hyun Yoo, Hyung-Chahn Lee, In-Chul Park, Chang Hun Rhee, Seok-Il Hong
Pages: 119-125
Published online on: 01 January 2006

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Article

Anticancer agents sensitize osteosarcoma cells to TNF-related apoptosis-inducing ligand downmodulating IAP family proteins

Prisco Mirandola, Ivonne Sponzilli, Giuliana Gobbi, Sandra Marmiroli, Laura Rinaldi, Roberto Binazzi, Gabriella Giuliani Piccari, Giulia Ramazzotti, Gian Carlo Gaboardi, Lucio Cocco, Marco Vitale
Pages: 127-133
Published online on: 01 January 2006

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Article

Extracellular signal-regulated kinases and AP-1 mediate the up-regulation of vascular endothelial growth factor by PDGF in human vascular smooth muscle cells

Hee J. Chang, Jung S. Park, Mi H. Kim, Min H. Hong, Ki M. Kim, Seok M. Kim, Boo A. Shin, Bong W. Ahn, Young D. Jung
Pages: 135-141
Published online on: 01 January 2006

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Article

Adenovirus E1A orchestrates the urokinase-plasminogen activator system and upregulates PAI-2 expression, supporting a tumor suppressor effect

V. Fernández-Soria, M. E. Lleonart, M. Diaz-Fuertes, R. Villuendas, R. Sánchez-Prieto, A. Fabra, S. Ramón y Cajal
Pages: 143-148
Published online on: 01 January 2006

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Article

The importance of functional testing in the genetic assessment of Muir-Torre syndrome, a clinical subphenotype of HNPCC

Saara Ollila, Roslyn Fitzpatrick, Laura Sarantaus, Reetta Kariola, Ingrid Ambus, Lea Velsher, Eugene Hsieh, Mette Klarskov Andersen, Tiina E. Raevaara, Anne-Marie Gerdes, Elisabeth Mangold, Päivi Peltomäki, Henry T. Lynch, Minna Nyström
Pages: 149-153
Published online on: 01 January 2006

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Article

The regulatory roles of cell surface sialylation and N-glycans in human B cell lymphoma cell adhesion to galectin-1

Osamu Suzuki, Yoshihiro Nozawa, Masafumi Abe
Pages: 155-160
Published online on: 01 January 2006

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Article

Antitumor triptycene analogs induce a rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria

Yang Wang, Elisabeth M. Perchellet, Mary M. Ward, Kaiyan Lou, Huiping Zhao, Srinivas K. Battina, Bernard Wiredu, Duy H. Hua, Jean-Pierre H. Perchellet
Pages: 161-172
Published online on: 01 January 2006

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Article

Comparative proteomic analysis of nucleic acid-binding proteins in ten human tumor cell lines

Leila Afjehi-Sadat, Ephrem Engidawork, Irene Slavc, Gert Lubec
Pages: 173-190
Published online on: 01 January 2006

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Article

CDK5 is a novel regulatory protein in PPARγ ligand-induced antiproliferation

Eugene Kim, Fei Chen, Chia-Chi Wang, Lawrence E. Harrison
Pages: 191-194
Published online on: 01 January 2006

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Article

Different expression of calgizzarin (S100A11) in normal colonic epithelium, adenoma and colorectal carcinoma

Christian Melle, Günther Ernst, Bettina Schimmel, Annett Bleul, Henning Mothes, Roland Kaufmann, Utz Settmacher, Ferdinand Von Eggeling
Pages: 195-200
Published online on: 01 January 2006

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Article

Role of MAPKs and NF-κB in diosgenin-induced megakaryocytic differentiation and subsequent apoptosis in HEL cells

David Y. Leger, Bertrand Liagre, Jean-Louis Beneytout
Pages: 201-207
Published online on: 01 January 2006

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Article

HPV-16 E6 oncoprotein impairs the fidelity of DNA end-joining via p53-dependent and -independent pathways

Ki-Hyuk Shin, Jae Hoon Ahn, Mo K. Kang, Philip K. Lim, Felix K. Yip, Marcel A. Baluda, No-Hee Park
Pages: 209-215
Published online on: 01 January 2006

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Article

Profiling of signaling molecules in four different human prostate carcinoma cell lines before and after induction of apoptosis

Iben H.E. Skjøth, Olaf-Georg Issinger
Pages: 217-229
Published online on: 01 January 2006

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Article

Polymorphisms in the glutathione S-transferase mu cluster are associated with tumour progression and patient outcome in colorectal cancer

Sarah L. Holley, Ramesh Rajagopal, Paul R. Hoban, Mark Deakin, Adeshina S. Fawole, James B. Elder, Jackie Elder, Victoria Smith, Richard C. Strange, Anthony A. Fryer
Pages: 231-236
Published online on: 01 January 2006

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Article

Effects of gemcitabine on cis-platinum-DNA adduct formation and repair in a panel of gemcitabine and cisplatin-sensitive or -resistant human ovarian cancer cell lines

Godefridus J. Peters, Catharina J.A. Van Moorsel, Bianca Lakerveld, Kees Smid, Paul Noordhuis, Elizabeth C. Comijn, Dennis Weaver, James C. Willey, Daphne Voorn, Wim J.F. Van der Vijgh, Herbert M. Pinedo
Pages: 237-244
Published online on: 01 January 2006

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Article

PI3K-Akt signaling is involved in the regulation of p21WAF/CIP expression and androgen-independent growth in prostate cancer cells

Shan Lu, Chengxi Ren, Yin Liu, Daniel E. Epner
Pages: 245-251
Published online on: 01 January 2006

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Article

Chemotherapy, IL-12 gene therapy and combined adjuvant therapy of HPV 16-associated MHC class I-proficient and -deficient tumours

Marie Indrová, Jana Bieblová, Tána Jandlová, Vladimír Vonka, Elzbieta Pajtasz-Piasecka, Milan Reinis
Pages: 253-259
Published online on: 01 January 2006

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Article

RANKL directly induces bone morphogenetic protein-2 expression in RANK-expressing POS-1 osteosarcoma cells

Yohann Wittrant, François Lamoureux, Kanji Mori, Anne Riet, Akira Kamijo, Dominique Heymann, Françoise Redini
Pages: 261-269
Published online on: 01 January 2006

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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Article Open Access

lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Review Open Access

Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Review Open Access

Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Review Open Access

Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Review Open Access

Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Review Open Access

Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Article Number: 55
Published online on: 09 March 2026

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Review Open Access

Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review)

Guirui Zhang, Yongmo Wu, Mingzhen Wei, Shupeng Huang, Qinghao Wang, Zhengyi Xie, Sisi Liu, Jin Wang
Article Number: 54
Published online on: 06 March 2026

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Retraction Open Access

[Retracted] Design, synthesis and preclinical evaluation of NRC‑AN‑019

Kompella Amala, A.k.S. Bhujanga Rao, Bharathi Gorantla, Christopher S.  Gondi, Jasti S. Rao
Article Number: 53
Published online on: 04 March 2026

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Article Open Access

FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma

Nawal Merjaneh, Ying-Wei Lan, Zicheng Deng, Johnny Donovan, Guolun Wang, Jonathan Do, Tiffany Juan, Xiaomei Xia, Vladimir V. Kalinichenko, Tanya V. Kalin
Article Number: 52
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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Article Open Access

RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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