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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2006 Volume 28 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Biology of insulin-like growth factor binding protein-4 and its role in cancer (review)

Rajaraman Durai, Mark Davies, Wenxuan Yang, Shi Yu Yang, Alexander Seifalian, Geoffrey Goldspink, Marc Winslet
Pages: 1317-1325
Published online on: 01 June 2006

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Article

Identification of genes with altered expression in medullary breast cancer vs. ductal breast cancer and normal breast epithelia

Morten F. Gjerstorff, Vivian M. Benoit, Anne-Vibeke Laenkholm, Ole Nielsen, Lene E. Johansen, Henrik J. Ditzel
Pages: 1327-1335
Published online on: 01 June 2006

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Article

Dendritic cell-based therapy for mantle cell lymphoma

Corey M. Munger, Julie M. Vose, Shantaram S. Joshi
Pages: 1337-1343
Published online on: 01 June 2006

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Article

Expression profiling of esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy: Clinical implications

Akio Ashida, Narikazu Boku, Kazuhiko Aoyagi, Hiroshi Sato, Yasuhiro Tsubosa, Keiko Minashi, Manabu Muto, Atsushi Ohtsu, Atsushi Ochiai, Teruhiko Yoshida, Shigeaki Yoshida, Hiroki Sasaki
Pages: 1345-1352
Published online on: 01 June 2006

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Article

RNAi-mediated downregulation of urokinase plasminogen activator and its receptor in human meningioma cells inhibits tumor invasion and growth

Shakuntala Kondraganti, Christopher S. Gondi, Ian McCutcheon, Dzung H. Dinh, Meena Gujrati, Jasti S. Rao, William C. Olivero
Pages: 1353-1360
Published online on: 01 June 2006

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Article

Deletion of the KIT gene is associated with liver metastasis and poor prognosis in patients with gastrointestinal stromal tumor in the stomach

Songde Cho, Yasuhiko Kitadai, Shigeto Yoshida, Shinji Tanaka, Masaharu Yoshihara, Kazuhiro Yoshida, Kazuaki Chayama
Pages: 1361-1367
Published online on: 01 June 2006

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Article

Poor outcome of patients with pulmonary adenocarcinoma showing decreased E-cadherin combined with increased S100A4 expression

Noriyuki Miyazaki, Yoshiyuki Abe, Yasuhisa Oida, Hiroshi Suemizu, Masatake Nishi, Hitoshi Yamazaki, Masayuki Iwasaki, Hiroshi Inoue, Yoshito Ueyama, Masato Nakamura
Pages: 1369-1374
Published online on: 01 June 2006

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Article

Genome-wide gene expression profile analysis of esophageal squamous cell carcinomas

Takumi Yamabuki, Yataro Daigo, Tatsuya Kato, Satoshi Hayama, Tatsuhiko Tsunoda, Masaki Miyamoto, Tomoo Ito, Masahiro Fujita, Masao Hosokawa, Satoshi Kondo, Yusuke Nakamura
Pages: 1375-1384
Published online on: 01 June 2006

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Article

Synergistic effect and condition of pegylated interferon α with paclitaxel on glioblastoma

Myung Jin Son, Hyun Seok Song, Mi Hyun Kim, Ji Tae Kim, Chang-Mo Kang, Ji Won Jeon, Shi-Young Park, Yung-Jin Kim, Morris D. Groves, Kwan Park, Jong-Hyun Kim, Do-Hyun Nam
Pages: 1385-1392
Published online on: 01 June 2006

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Article

Effects of ghrelin on anorexia in tumor-bearing mice with eicosanoid-related cachexia

Wenhua Wang, Marianne Andersson, Britt-Marie Iresjö, Christina Lönnroth, Kent Lundholm
Pages: 1393-1400
Published online on: 01 June 2006

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Article

Combination treatment with arsenic trioxide and sulindac augments their apoptotic potential in lung cancer cells through activation of caspase cascade and mitochondrial dysfunction

Hak-Ryul Kim, Eun-Jung Kim, Sei-Hoon Yang, Eun-Taik Jeong, Channy Park, Se-Jin Kim, Myung-Ja Youn, Hong-Seob So, Raekil Park
Pages: 1401-1408
Published online on: 01 June 2006

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Article

LAGλ-1: A clinically relevant drug resistant human multiple myeloma tumor murine model that enables rapid evaluation of treatments for multiple myeloma

Richard A. Campbell, Steven J. Manyak, Honghao H. Yang, Nelida N. Sjak-Shie, Haiming Chen, Dorina Gui, Laura Popoviciu, Cathy Wang, Melinda Gordon, Shen Pang, Benjamin Bonavida, Jonathan Said, James R. Berenson
Pages: 1409-1417
Published online on: 01 June 2006

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Article

Specific immune recognition of pancreatic carcinoma by patient-derived CD4 and CD8 T cells and its improvement by interferon-γ

F. H. Schmitz-Winnenthal, L. V. Galindo Escobedo, P. Beckhove, V. Schirrmacher, M. Bucur, Y. Ziouta, C. Volk, B. Schmied, M. Koch, D. Antolovic, J. Weitz, M. W. Büchler, K. Z'graggen
Pages: 1419-1428
Published online on: 01 June 2006

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Article

Estrogen enhances the efficacy of an oncolytic HSV-1 mutant in the treatment of estrogen receptor-positive breast cancer

Brendon M. Stiles, Prasad S. Adusumilli, Stephen F. Stanziale, David P. Eisenberg, Amit Bhargava, Teresa H. Kim, Mei-Ki Chan, Rumana Huq, Mithat Gonen, Yuman Fong
Pages: 1429-1439
Published online on: 01 June 2006

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Article

Transcriptome characterization of human mammary cell lines expressing different levels of ERBB2 by serial analysis of gene expression

Mariana Lopes Dos Santos, Carolina Gonçalves Palanch, Sibeli Salaorni, Wilson Araujo Da Silva, Maria Aparecida Nagai
Pages: 1441-1461
Published online on: 01 June 2006

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Article

Urokinase-type plasminogen activator induces proliferation in breast cancer cells

Mukesh Gandhari, Norbert Arens, Meher Majety, Alexandra Dorn-Beineke, Ralf Hildenbrand
Pages: 1463-1470
Published online on: 01 June 2006

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Article

Differential targeting of protein kinase B in cell death induced by sulindac and its metabolite sulindac sulfide

Anthony Marotta, Kuljit Parhar, Rajinder Hundal, Vincent Duronio, Baljinder Salh
Pages: 1471-1479
Published online on: 01 June 2006

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Article

Mature dendritic cells generated from patient-derived peripheral blood monocytes in one-step culture using streptococcal preparation OK-432 exert an enhanced antigen-presenting capacity

Kei Naito, Yuji Ueda, Tsuyoshi Itoh, Nobuaki Fuji, Keiji Shimizu, Yutaro Yano, Yoshiki Yamamoto, Kenichiro Imura, Junji Kohara, Arihiro Iwamoto, Atsushi Shiozaki, Hidemasa Tamai, Takeshi Shimizu, Osam Mazda, Hisakazu Yamagishi
Pages: 1481-1489
Published online on: 01 June 2006

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Article

Induction of DNA double-strand breaks in A549 and normal human pulmonary epithelial cells by cigarette smoke is mediated by free radicals

Anthony P. Albino, Xuan Huang, Ellen D. Jorgensen, Diana Gietl, Frank Traganos, Zbigniew Darzynkiewicz
Pages: 1491-1505
Published online on: 01 June 2006

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Article

Effective therapy of experimental human malignant melanomas with a targeted cytotoxic somatostatin analogue without induction of multi-drug resistance proteins

Gunhild Keller, Andrew V. Schally, Attila Nagy, Benjamin Baker, Gabor Halmos, Jörg B. Engel
Pages: 1507-1513
Published online on: 01 June 2006

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Article

Polyamine depletion and cell cycle manipulation in combination with HSV thymidine kinase/ganciclovir cancer gene therapy

Tiina Wahlfors, Anne Karppinen, Juhani Jänne, Leena Alhonen, Jarmo Wahlfors
Pages: 1515-1522
Published online on: 01 June 2006

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Review

Prevention of early-onset familial/hereditary colon cancer: New models and mechanistic biomarkers (Review)

Nitin T. Telang, Guo Li, Meena Katdare
Pages: 1523-1529
Published online on: 01 June 2006

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Article

Effective silencing of EGFR with RNAi demonstrates non-EGFR dependent proliferation of glioma cells

Arabel Vollmann, Hans-Peter Vornlocher, Thomas Stempfl, Gero Brockhoff, Rainer Apfel, Ulrich Bogdahn
Pages: 1531-1542
Published online on: 01 June 2006

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Article

Hyperthermia enhances cytotoxicity of amine oxidase and spermine on drug-resistant LoVo colon adenocarcinoma cells

Enzo Agostinelli, Francesca Belli, Laura Dalla Vedova, Manuela Marra, Pasqualina Crateri, Giuseppe Arancia
Pages: 1543-1553
Published online on: 01 June 2006

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Article

Telomerase activity and hTERT mRNA expression in glial tumors

L. Boldrini, S. Pistolesi, S. Gisfredi, S. Ursino, G. Ali, N. Pieracci, F. Basolo, G. Parenti, G. Fontanini
Pages: 1555-1560
Published online on: 01 June 2006

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Article

Synthesis and in vitro investigation of cationic 5,15-diphenyl porphyrin-monoclonal antibody conjugates as targeted photodynamic sensitisers

Nela Malatesti, Karen Smith, Huguette Savoie, John Greenman, Ross W. Boyle
Pages: 1561-1569
Published online on: 01 June 2006

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Article

Primary bone lymphoma: A retrospective analysis

J. M. Horsman, J. Thomas, R. Hough, B. W. Hancock
Pages: 1571-1575
Published online on: 01 June 2006

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Article

Progression of squamous cell carcinoma of the head and neck is associated with down-regulation of the opioid growth factor receptor

Patricia J. McLaughlin, Ian S. Zagon
Pages: 1577-1583
Published online on: 01 June 2006

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Article

Comparative integromics on VEGF family members

Yuriko Katoh, Masaru Katoh
Pages: 1585-1589
Published online on: 01 June 2006

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Review Open Access

Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Review Open Access

Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Selective antitumor and apoptosis‑inducing effects of the Src inhibitor PP1 in human tongue squamous cell carcinoma cells

Shirinbaeva Luiza Kantibekovna, Saini Wang, Hyunju Kang, Young-Min Shin, Byeong-Churl Jang
Article Number: 64
Published online on: 27 March 2026

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Multifaceted roles of miR‑124 in cancer: Molecular mechanisms and clinical prospects (Review)

Jun Guo, Yunyan Guo, Peiyang Chen, Wenyan Xiao, Yuxiang Tan, Zhiyong Wang, Yanxin Lu, Xupeng Yue
Article Number: 63
Published online on: 24 March 2026

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Article Open Access

Hypoxia‑induced exosomal CAMTA1 promotes radio‑resistance in MDA‑MB‑231 cells by regulating NRG1 to mediate M2 macrophage polarization

Qian Li, Minghua Jiang, Biqing Zhu, Wei Wei, Lei Xia, Jian Huang, Han Gao, Mingyu Du
Article Number: 62
Published online on: 20 March 2026

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Correction Open Access

[Corrigendum] Epithelial protein lost in neoplasm‑α (EPLIN‑α) is a potential prognostic marker for the progression of epithelial ovarian cancer

Rong Liu, Tracey A. Martin, Nicola J. Jordan, Fiona Ruge, Lin Ye, Wen G. Jiang
Article Number: 61
Published online on: 18 March 2026

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Review Open Access

Crosstalk between KRAS and miRNAs in pancreatic cancer: Opportunities for its diagnosis, prognosis and therapeutic intervention (Review)

Abdulaziz A. Aloliqi, Abdullah M. Alnuqaydan, Mohammad Alshebremi, Arshad Husain Rahmani, Amjad Ali Khan
Article Number: 60
Published online on: 18 March 2026

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Article Open Access

Smoking promotes colorectal cancer via the CKAP2L/AREG axis

Shasha Wu, Feixiang Wu, Xiaoqing Li, Zhihang Jiang, Fuqiang Liu, Zheng Jiang
Article Number: 59
Published online on: 13 March 2026

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Article Open Access

Diverse roles of SERPINE1 in regulating cellular proliferation and invasion

Wei Wang, Pengfei Zhao, Tian Wang, Weijing Wu, Jing Li, Qiang Huang, Jing Mo
Article Number: 58
Published online on: 13 March 2026

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Therapeutic implications of targeting cancer testis antigen MAGEA1 in cervical cancer

Ayoung Kim, Jina Kim, Woori Kwak, Kyumin Mo, Soohyun Choe, Minyeong Jeon, Jisun Lee, Jun-Won Yun, Hyunho Yoon
Article Number: 57
Published online on: 12 March 2026

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Review Open Access

Enolase 1: A paradigm of metabolic enzyme moonlighting in tumorigenesis (Review)

Xiaochen Ni, Mingsi Zhang, Kaiyuan Zhang, Chuhang Wang, Jianing Guo, Wei Fan, Linfeng Zheng, Tao Jiang, Guangji Zhang
Article Number: 56
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Article Number: 55
Published online on: 09 March 2026

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Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review)

Guirui Zhang, Yongmo Wu, Mingzhen Wei, Shupeng Huang, Qinghao Wang, Zhengyi Xie, Sisi Liu, Jin Wang
Article Number: 54
Published online on: 06 March 2026

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Retraction Open Access

[Retracted] Design, synthesis and preclinical evaluation of NRC‑AN‑019

Kompella Amala, A.K.S. Bhujanga Rao, Bharathi Gorantla, Christopher S.  Gondi, Jasti S. Rao
Article Number: 53
Published online on: 04 March 2026

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Article Open Access

FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma

Nawal Merjaneh, Ying-Wei Lan, Zicheng Deng, Johnny Donovan, Guolun Wang, Jonathan Do, Tiffany Juan, Xiaomei Xia, Vladimir V. Kalinichenko, Tanya V. Kalin
Article Number: 52
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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