Journal Articles

Open Access

The tumor microenvironment in hepatocellular carcinoma (Review)

Giulia Costanza Leonardi, Saverio Candido, Melchiorre Cervello, Daria Nicolosi, Fabio Raiti, Salvatore Travali, Demetrios A. Spandidos, Massimo Libra

Pages: 1733-1747 Published online on: 22 March 2012
Open Access

ETS transcription factors and prostate cancer: The role of the family prototype ETS-1 (Review)

Zaki Shaikhibrahim, Nicolas Wernert

Pages: 1748-1754 Published online on: 21 February 2012
Open Access

Progestin therapy for endometrial cancer: The potential of fourth-generation progestin (Review)

Kouji Banno, Iori Kisu, Megumi Yanokura, Kosuke Tsuji, Kenta Masuda, Arisa Ueki, Yusuke Kobayashi, Wataru Yamagami, Hiroyuki Nomura, Nobuyuki Susumu, Daisuke Aoki

Pages: 1755-1762 Published online on: 21 February 2012

Structural analysis of the EGFR TK domain and potential implications for EGFR targeted therapy

Weiwei Nie, Lin Tang, Haiyang Zhang, Jiaqing Shao, Yucai Wang, Longbang Chen, Donghai Li, Xiaoxiang Guan

Pages: 1763-1769 Published online on: 03 February 2012
Open Access

Actin-related protein 2/3 complex subunit 5 (ARPC5) contributes to cell migration and invasion and is directly regulated by tumor-suppressive microRNA-133a in head and neck squamous cell carcinoma

Takashi Kinoshita, Nijiro Nohata, Haruko Watanabe-Takano, Hirofumi Yoshino, Hideo Hidaka, Lisa Fujimura, Miki Fuse, Takeshi Yamasaki, Hideki Enokida, Masayuki  Nakagawa, Toyoyuki Hanazawa, Yoshitaka Okamoto, Naohiko Seki

Pages: 1770-1778 Published online on: 29 February 2012
Open Access

Preventive effect of caffeine and curcumin on hepato­carcinogenesis in diethylnitrosamine-induced rats Corrigendum in /10.3892/ijo.2016.3577

Yuki Fujise, Jun-Ichi Okano, Takakazu Nagahara, Ryo Abe, Ryu Imamoto, Yoshikazu Murawaki

Pages: 1779-1788 Published online on: 24 January 2012
Open Access

High enzyme activity UGT1A1 or low activity UGT1A8 and UGT2B4 genotypes increase esophageal cancer risk

Polat Dura, Jody Salomon, Rene H.M. te Morsche, Hennie M.J. Roelofs, Jon O. Kristinsson, Theo Wobbes, Ben J.M. Witteman, Adriaan C.I.T.L. Tan, Joost P.H. Drenth, Wilbert H.M. Peters

Pages: 1789-1796 Published online on: 22 February 2012
Open Access

Impact of carbamylation and glycation of collagen type I on migration of HT1080 human fibrosarcoma cells

Georges Said, Marie Guilbert, Emilie Millerot-Serrurot, Laurence Van Gulick, Christine Terryn, Roselyne Garnotel, Pierre Jeannesson

Pages: 1797-1804 Published online on: 29 February 2012

Combined molecular targeted drug therapy for EGFR and HER-2 in head and neck squamous cell carcinoma cell lines

Norio Kondo, Mamoru Tsukuda, Atsuko Sakakibara, Hideaki Takahashi, Hiroshi Hyakusoku, Masanori Komatsu, Tatsuo Niho, Kouichi Nakazaki, Gabor Toth

Pages: 1805-1812 Published online on: 16 February 2012

Differential expression profiles of sense and antisense transcripts between HCV-associated hepatocellular carcinoma and corresponding non-cancerous liver tissue

Kentaro Nagai, Keisuke Kohno, Mitsuru Chiba, Sugiru Pak, Soichiro Murata, Kiyoshi Fukunaga, Akihiko Kobayashi, Hiroshi Yasue, Nobuhiro Ohkohchi

Pages: 1813-1820 Published online on: 21 February 2012

Novel molecular targets regulated by tumor suppressors microRNA-1 and microRNA-133a in bladder cancer

Takeshi Yamasaki, Hirofumi Yoshino, Hideki Enokida, Hideo Hidaka, Takeshi Chiyomaru, Nijiro Nohata, Takashi Kinoshita, Miki Fuse, Naohiko Seki, Masayuki Nakagawa

Pages: 1821-1830 Published online on: 29 February 2012

MUC1 carrying core 2 O-glycans functions as a molecular shield against NK cell attack, promoting bladder tumor metastasis

Yuichiro Suzuki, Mihoko Sutoh, Shingo Hatakeyama, Kazuyuki Mori, Hayato Yamamoto, Takuya Koie, Hisao Saitoh, Kanemitsu Yamaya, Tomihisa Funyu, Tomonori Habuchi, Yoichi Arai, Minoru Fukuda, Chikara Ohyama, Shigeru Tsuboi

Pages: 1831-1838 Published online on: 23 March 2012

PKD1 negatively regulates cell invasion, migration and proliferation ability of human osteosarcoma

Yasuo Onishi, Teruya Kawamoto, Kenta Kishimoto, Hitomi Hara, Naomasa Fukase, Mitsunori Toda, Risa Harada, Masahiro Kurosaka, Toshihiro Akisue

Pages: 1839-1848 Published online on: 12 March 2012

Emodin potentiates the antitumor effects of gemcitabine in PANC-1 pancreatic cancer xenograft model in vivo via inhibition of inhibitors of apoptosis

Hong-Chun Guo, He-Qi Bu, Jiang Luo, Wei-Tian Wei, Dian-Lei Liu, Hui Chen, Hong-Fei Tong, Zhao-Hong Wang, Hua-Yong Wu, Hong-Hai Li, Ming-Ming Zuo, Wei Li, Sheng-Zhang Lin

Pages: 1849-1857 Published online on: 29 February 2012

Raf-1 oncogenic signaling is linked to activation of mesenchymal to epithelial transition pathway in metastatic breast cancer cells

Alexey A. Leontovich, Shuya Zhang, Cosima Quatraro, Ianko Iankov, Pier Francesco Veroux, Mario W. Gambino, Amy Degnim, James McCubrey, James Ingle, Evanthia Galanis, Antonino B. D'Assoro

Pages: 1858-1864 Published online on: 19 March 2012

Chromosome 17q25 genes, RHBDF2 and CYGB, in ovarian cancer

Paulina M. Wojnarowicz, Diane M. Provencher, Anne-Marie Mes-Masson, Patricia N. Tonin

Pages: 1865-1880 Published online on: 14 February 2012

Significant systemic therapeutic effects of high-LET immunoradiation by 212Pb-trastuzumab against prostatic tumors of androgen-independent human prostate cancer in mice

Zongqing Tan, Pingping Chen, Nathan Schneider, Samuel Glover, Lingling Cui, Julien Torgue, Olivier Rixe, Henry B. Spitz, Zhongyun Dong

Pages: 1881-1888 Published online on: 06 February 2012

PDEF downregulates stathmin expression in prostate cancer

Yamini Sabherwal, Nitin Mahajan, Donald L. Helseth, Mayumi Gassmann, Heidi Shi, Ming Zhang

Pages: 1889-1899 Published online on: 29 February 2012

Development of a rapid and practical mutation screening assay for human lung adenocarcinoma

Helen Choi, Johannes Kratz, Patrick Pham, Sharon Lee, Roshni Ray, Yong-Won Kwon, Jian-Hua Mao, Hio Chung Kang, David Jablons, Il-Jin Kim

Pages: 1900-1906 Published online on: 07 March 2012

Loss of NKX3-1 as a potential marker for an increased risk of occult lymph node metastasis and poor prognosis in oral squamous cell carcinoma

Ken Miyaguchi, Narikazu Uzawa, Kaoru Mogushi, Ken-Ichiro  Takahashi, Chieko  Michikawa, Yoshimi Nakata, Jun Sumino, Norihiko  Okada, Hiroshi Mizushima, Yutaka Fukuoka, Hiroshi Tanaka

Pages: 1907-1914 Published online on: 14 February 2012

Properties of bcr-abl-transformed mouse 12B1 cells secreting interleukin-2 and granulocyte-macrophage colony stimulating factor (GM-CSF): II. Adverse effects of GM-CSF

Martina Petráčková, Libor Staněk, Václav Mandys, Pavel Dundr, Vladimír Vonka

Pages: 1915-1922 Published online on: 22 March 2012

Alternariol induces DNA polymerase β expression through the PKA-CREB signaling pathway

Jimin Zhao, Kangdong Liu, Jing Lu, Junfen Ma, Xiaoyan Zhang, Yanan Jiang, Hongyan Yang, Ge Jin, Guoqiang Zhao, Mingyao Zhao, Ziming Dong

Pages: 1923-1928 Published online on: 08 March 2012

Role of autophagy in apoptosis induction by methylene chloride extracts of Mori cortex in NCI-H460 human lung carcinoma cells

Shin-Hyung Park, Gyoo Yong Chi, Hyun Sup Eom, Gi-Young Kim, Jin  Won Hyun, Wun-Jae Kim, Su-Jae Lee, Young Hyun Yoo, Yung Hyun Choi

Pages: 1929-1940 Published online on: 22 February 2012

Tunicamycin sensitizes human prostate cells to TRAIL-induced apoptosis by upregulation of TRAIL receptors and downregulation of cIAP2

Young-Hwa Jung, Eun Jin Lim, Jeonghoon Heo, Taeg Kyu Kwon, Young-Ho Kim

Pages: 1941-1948 Published online on: 15 March 2012

Cerulenin-induced apoptosis is mediated by disrupting the interaction between AIF and hexokinase II

Na Young Jeong, Young Hyun Yoo

Pages: 1949-1956 Published online on: 15 March 2012

Anti-HuC and -HuD autoantibodies are differential sero-diagnostic markers for small cell carcinoma from large cell neuroendocrine carcinoma of the lung

Toshihide Matsumoto, Shinichiro Ryuge, Makoto Kobayashi, Taihei Kageyama, Manabu Hattori, Naoki Goshima, Shi-Xu Jiang, Makoto Saegusa, Akira Iyoda, Yukitoshi Satoh, Noriyuki Masuda, Yuichi Sato

Pages: 1957-1962 Published online on: 16 March 2012

Approaches to sensitizing glioblastoma to radiotherapy: Use of lentiviral vectors

Teong Lip Chuah, David Gregory Walker, Ming Wei, Shaun Scott, Martin Francis Lavin

Pages: 1963-1969 Published online on: 22 March 2012

Ginsenoside compound K, not Rb1, possesses potential chemopreventive activities in human colorectal cancer

Chong-Zhi Wang, Guang-Jian Du, Zhiyu Zhang, Xiao-Dong Wen, Tyler Calway, Zhong Zhen, Mark W. Musch, Marc Bissonnette, Eugene B. Chang, Chun-Su Yuan

Pages: 1970-1976 Published online on: 12 March 2012

New alternatively spliced variant of prostate-specific membrane antigen PSM-E suppresses the proliferation, migration and invasiveness of prostate cancer cells

Kai-Yuan Cao, Lin Xu, Ding-Mei Zhang, Xiao-Ming Zhang, Tian Zhang, Xia He, Zhu Wang, Fa-Shen Feng, Shao-Peng Qiu, Guan-Xin Shen

Pages: 1977-1985 Published online on: 06 February 2012

Cancer/testis antigen SSX2 enhances invasiveness in MCF-7 cells by repressing ERα signaling

Ling Chen, Wen-Bin Zhou, Yi Zhao, Xiao-An Liu, Qiang Ding, Xiao-Ming Zha, Shui Wang

Pages: 1986-1994 Published online on: 13 February 2012

Identification of blood protein biomarkers that aid in the clinical assessment of patients with malignant glioma

Baogang J. Xu, Qi A. An, Supriya Srinivasa Gowda, Wenwei Yan, Larry A. Pierce, Ty W. Abel, Sarah Z. Rush, Michael K. Cooper, Fei Ye, Yu Shyr, Kyle D. Weaver, Reid C. Thompson

Pages: 1995-2003 Published online on: 03 February 2012

LncRNA profile of glioblastoma reveals the potential role of lncRNAs in contributing to glioblastoma pathogenesis

Lei Han, Kailiang Zhang, Zhendong Shi, Junxia Zhang, Jialin Zhu, Shanjun Zhu, Anling Zhang, Zhifan Jia, Guangxiu Wang, Shizhu Yu, Peiyu Pu, Lun Dong, Chunsheng Kang

Pages: 2004-2012 Published online on: 23 March 2012

Expression of Müllerian inhibiting substance type II receptor and antiproliferative effects of MIS on human cervical cancer

Jae Yen Song, Hyun Hee Jo, Mee Ran Kim, Young Oak Lew, Ki Sung Ryu, Jung Ho Cha, Chang Suk Kang, Patricia K. Donahoe, David T. MacLaughlin, Jang Heub Kim

Pages: 2013-2021 Published online on: 14 February 2012

Human amniotic membrane-derived epithelial stem cells display anticancer activity in BALB/c female nude mice bearing disseminated breast cancer xenografts

Nam-Hee Kang, Bo-Rim Yi, So Yoon Lim, Kyung-A Hwang, Young Seok Baek, Kyung-Sun Kang, Kyung-Chul Choi

Pages: 2022-2028 Published online on: 14 February 2012

Inhibition of cyclooxygenase-2 by tetramethylpyrazine and its effects on A549 cell invasion and metastasis

Chun-Yan Zheng, Wei Xiao, Mao-Xiang Zhu, Xiu-Jie Pan, Zhi-Hua Yang, Sheng-Yu Zhou

Pages: 2029-2037 Published online on: 16 February 2012

Krüppel-like factor 4 negatively regulates β-catenin expression and inhibits the proliferation, invasion and metastasis of gastric cancer

Neng Zhang, Jun Zhang, Leiyuan Shuai, Lang Zha, Miao He, Zhen Huang, Ziwei Wang

Pages: 2038-2048 Published online on: 07 March 2012

Emerging role of autophagy during ischemia-hypoxia and reperfusion in hepatocellular carcinoma

Hailei Du, Weiping Yang, Lin Chen, Baiyong Shen, Chenghong Peng, Hongwei Li, David K. Ann, Yun Yen, Weihua Qiu

Pages: 2049-2057 Published online on: 26 March 2012

Comparison of immunohistochemistry, DNA sequencing and allele-specific PCR for the detection of IDH1 mutations in gliomas

Delphine Loussouarn, Anne-Gaëlle Le Loupp, Jean-Sébastien Frenel, François Leclair, Andreas Von Deimling, Maud Aumont, Stéphane Martin, Mario Campone, Marc G. Denis

Pages: 2058-2062 Published online on: 16 March 2012

Effects of Scrophularia extracts on tumor cell proliferation, death and intravasation through lymphoendothelial cell barriers

Benedikt Giessrigl, Gökhan Yazici, Mathias Teichmann, Sabine Kopf, Sara Ghassemi, Atanas G. Atanasov, Verena M. Dirsch, Michael Grusch, Walter Jäger, Ali Özmen, Georg Krupitza

Pages: 2063-2074 Published online on: 22 February 2012

Primary thyroid lymphoma: The 40 year experience of a UK lymphoma treatment centre

M. Alzouebi, J. R. Goepel, J. M. Horsman, B. W. Hancock

Pages: 2075-2080 Published online on: 22 February 2012

A Herpesvirus saimiri-based vector expressing TRAIL induces cell death in human carcinoma cell lines and multicellular spheroid cultures

Susan J. Turrell, Stuart A. Macnab, Ailsa Rose, Alan A. Melcher, Adrian Whitehouse

Pages: 2081-2089 Published online on: 01 March 2012

Citrus aurantium L. exhibits apoptotic effects on U937 human leukemia cells partly through inhibition of Akt

Min Ho Han, Won Sup Lee, Jing Nan Lu, Gonsup Kim, Jin Myung Jung, Chung Ho Ryu, Gi-Young Kim, Hye Jin Hwang, Taeg Kyu Kwon, Yung Hyun Choi

Pages: 2090-2096 Published online on: 01 February 2012

Tumor microRNA-29a expression and the risk of recurrence in stage II colon cancer

Alina Weissmann-Brenner, Michal Kushnir, Gila Lithwick Yanai, Ranit Aharonov, Hadas Gibori, Ofer Purim, Yulia Kundel, Sara Morgenstern, Marissa Halperin, Yaron Niv, Baruch Brenner

Pages: 2097-2103 Published online on: 16 March 2012

ERCC1 and topoisomerase I expression in small cell lung cancer: Prognostic and predictive implications

Maria Sereno, Paloma Cejas, Víctor Moreno, Cristóbal Belda-Iniesta, Rocio López, Manuel Nistal, Jaime Feliu, Javier De Castro Carpeño

Pages: 2104-2110 Published online on: 16 February 2012

Down-regulated expression of apoptosis-associated genes APIP and UACA in non-small cell lung carcinoma

Erika Moravcikova, Evzen Krepela, Jan Prochazka, Ilona Rousalova, Jan Cermak, Kamila Benkova

Pages: 2111-2121 Published online on: 07 March 2012

Hypoxia promotes glycogen synthesis and accumulation in human ovarian clear cell carcinoma

Yasushi Iida, Katsuhiko Aoki, Tadashi Asakura, Kazu Ueda, Nozomu Yanaihara, Satoshi Takakura, Kyosuke Yamada, Aikou Okamoto, Tadao Tanaka, Kiyoshi Ohkawa

Pages: 2122-2130 Published online on: 19 March 2012

An apolar extract of Critonia morifolia inhibits c-Myc, cyclin D1, Cdc25A, Cdc25B, Cdc25C and Akt and induces apoptosis

Christine Unger, Ruxandra Popescu, Benedikt Giessrigl, Lucie Rarova, Irene Herbacek, Mareike Seelinger, Rene Diaz, Bruno Wallnöfer, Monika Fritzer-Szekeres, Thomas Szekeres, Richard Frisch, Karel Doležal, Miroslav Strnad, Rainer De Martin, Michael Grusch, Brigitte Kopp, Georg Krupitza

Pages: 2131-2139 Published online on: 23 March 2012

Valproic acid, a histone deacetylase inhibitor, enhances radiosensitivity in esophageal squamous cell carcinoma

Masatoshi Shoji, Itasu Ninomiya, Isamu Makino, Jun Kinoshita, Keishi Nakamura, Katsunobu Oyama, Hisatoshi Nakagawara, Hideto Fujita, Hidehiro Tajima, Hiroyuki Takamura, Hirohisa Kitagawa, Sachio Fushida, Shinichi Harada, Takashi Fujimura, Tetsuo Ohta

Pages: 2140-2146 Published online on: 26 March 2012
Journal Cover

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June 2012
Volume 40 Issue 6

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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