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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2005 Volume 13 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Aspirin, ibuprofen, and other non-steroidal anti-inflammatory drugs in cancer prevention: A critical review of non-selective COX-2 blockade (Review)

Randall E. Harris, Joanne Beebe-Donk, Hani Doss, Deborah Burr Doss
Pages: 559-583
Published online on: 01 April 2005

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Article

Rat soluble tumor-associated antigens inhibit chemically-induced mammary tumorigenesis in syngeneic rats

George Kossoy, Herzl Ben-Hur, Asher Elhayany, David F. Schneider, Itshak Zusman
Pages: 585-588
Published online on: 01 April 2005

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Article

Pharmacokinetics and adverse reactions of a new liposomal cisplatin (Lipoplatin): Phase I study

George P. Stathopoulos, Teni Boulikas, Maria Vougiouka, George Deliconstantinos, Sotirios Rigatos, Eleftheria Darli, Vasiliki Viliotou, John G. Stathopoulos
Pages: 589-595
Published online on: 01 April 2005

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Expression of thymidine phosphorylase correlates with microvessel density in prostate cancer

Akira Kataoka, Takeshi Yuasa, Susumu Kageyama, Hideaki Iwaki, Kayoko Higuchi, Tsutomu Tanaka, Yusaku Okada, Tatsuhiro Yoshiki
Pages: 597-600
Published online on: 01 April 2005

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Article

Relationship between peroxisome proliferator-activated receptor-γ expression and differentiation of human esophageal squamous cell carcinoma

Takashi Takashima, Yasuhiro Fujiwara, Masaki Hamaguchi, Eiji Sasaki, Kazunari Tominaga, Toshio Watanabe, Nobuhide Oshitani, Kazuhide Higuchi, Tetsuo Arakawa
Pages: 601-606
Published online on: 01 April 2005

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Article

Changes of histological and biological features by serial passages in a human adenoid cystic carcinoma line transplantable in nude mice

Susumu Hashitani, Kazuma Noguchi, Yukiyo Manno, Kuniyasu Moridera, Kazuki Takaoka, Norihiko Nishimura, Hiromitsu Kishimoto, Kazunari Sakurai, Masahiro Urade
Pages: 607-612
Published online on: 01 April 2005

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Article

Expression of cell adhesion molecules and chemokine receptors: Angioinvasiveness in nasal NK/T-cell lymphoma

Angen Liu, Shin-ichi Nakatsuka, Woo-Ick Yang, Shizuo Kojya, Katsuyuki Aozasa
Pages: 613-620
Published online on: 01 April 2005

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Article

Thymidine phosphorylase expression and efficacy of adjuvant doxifluridine in advanced colorectal cancer patients

Shiro Hasegawa, Kazuhiro Seike, Keiji Koda, Nobuhiro Takiguchi, Kenji Oda, Rumiko Hasegawa, Masaru Miyazaki
Pages: 621-626
Published online on: 01 April 2005

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Article

Venous thromboembolism in colorectal cancer patients with central venous catheters for 5-FU infusion-based pharmacokinetic modulating chemotherapy

Reigetsu Yoshikawa, Hidenori Yanagi, Masafumi Noda, Hiroki Ikeuchi, Hiroki Nakano, Makoto Gega, Kiyoshi Tsukamoto, Tsutomu Oshima, Takashi Inoue, Yoshinori Fujiwara, Yasutsugu Shoji, Takatoshi Sakaki, Satoshi Higasa, Tomoko Hashimoto-Tamaoki, Takehira Yamamura
Pages: 627-632
Published online on: 01 April 2005

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Article

Detection of Her2/neu, c-MYC and ZNF217 gene amplification during breast cancer progression using fluorescence in situ hybridization

Masayuki Shimada, Johji Imura, Takazumi Kozaki, Takahiro Fujimori, Shuichi Asakawa, Nobuyoshi Shimizu, Ryuji Kawaguchi
Pages: 633-641
Published online on: 01 April 2005

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Article

Expression of c-kit (CD117) in neuroendocrine tumours - a target for therapy?

Virginia Kostoula, Korsa Khan, Kay Savage, Mark Stubbs, Alberto Quaglia, Amar P. Dhillon, Daniel Hochhauser, Martyn E. Caplin
Pages: 643-647
Published online on: 01 April 2005

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Article

Atypical lipomatous tumor with rare structural rearrangements involving chromosomes 8 and 12

Malin Nilsson, Henryk Domanski, Fredrik Mertens, Nils Mandahl
Pages: 649-652
Published online on: 01 April 2005

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Article

Antiproliferation effects of ponicidin on human myeloid leukemia cells in vitro

Jia-Jun Liu, Ren-Wei Huang, Dong-Jun Lin, Xiang-Yuan Wu, Qu Lin, Jun Peng, Xianglin Pan, Yu-Qin Song, Mao-hong Zhang, Ming Hou, Feng Chen
Pages: 653-657
Published online on: 01 April 2005

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Article

Inhibition of cell cycle and induction of apoptosis by sulforaphane in cell lines carrying various inherited BRCA1 mutations

Irena Misiewicz, Agata Kozar, Katarzyna Skupinska, Elzbieta Kowalska, Jan Lubinski, Teresa Kasprzycka-Guttman
Pages: 659-665
Published online on: 01 April 2005

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Article

Long-term administration of low-dose cisplatin plus 5-fluorouracil prolongs the postoperative survival of patients with esophageal cancer

Atsushi Shiozaki, Hisakazu Yamagishi, Hirosumi Itoi, Hitoshi Fujiwara, Shojiro Kikuchi, Kazuma Okamoto, Daisuke Ichikawa, Nobuaki Fuji, Toshiya Ochiai, Teruhisa Sonoyama, Yuji Ueda
Pages: 667-672
Published online on: 01 April 2005

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Article

Aberrant expression of HOX genes in human invasive breast carcinoma

Kokonoe Makiyama, Jun-ichi Hamada, Minoru Takada, Katsuhiko Murakawa, Yoko Takahashi, Mitsuhiro Tada, Eiji Tamoto, Gaku Shindo, Akihiro Matsunaga, Ken-ichi Teramoto, Kazuteru Komuro, Satoshi Kondo, Hiroyuki Katoh, Takao Koike, Tetsuya Moriuchi
Pages: 673-679
Published online on: 01 April 2005

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Article

Irinotecan combined or alternated with bolus 5-fluorouracil and folinic acid versus the Mayo Clinic regimen in the first-line therapy of advanced colorectal cancer

Ullrich Graeven, Karsten Ridwelski, Maja Artandi, Pilar Espana, Jürgen Schölmerich, Adolfo M. Rosales, Göran CARLSSON, Markus Borner, Blandine Boussard, Wolff Schmiegel
Pages: 681-688
Published online on: 01 April 2005

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Article

Pro-neoangiogenic cytokines (VEGF and bFGF) and anemia in solid tumor patients

Camillo Porta, Ilaria Imarisio, Mara De Amici, Lucia Bonomi, Chiara Paglino, Elisa Biscaldi, Matteo Zimatore, Andrea Sartore-Bianchi, Marco Danova, Remigio Moratti, Alberto Riccardi
Pages: 689-695
Published online on: 01 April 2005

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Article

Predictive value of COX-2 for the effect of chemoradiotherapy on esophageal squamous cell carcinoma

Hiroyuki Takatori, Shoji Natsugoe, Hiroshi Okumura, Masataka Matsumoto, Sumiya Ishigami, Tetsuhiro Owaki, Takashi Aikou
Pages: 697-701
Published online on: 01 April 2005

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Article

Infrequent mutation of the human envoplakin gene is closely linked to the tylosis oesophageal cancer locus in sporadic oesophageal squamous cell carcinomas

Takeshi Iwaya, Chihaya Maesawa, Toshimoto Kimura, Satoshi Ogasawara, Kenichro Ikeda, Yusuke Kimura, Yoshinori Noda, Kaoru Ishida, Nobuhiro Sato, Kazuyoshi Saito, Tomoyuki Masuda
Pages: 703-707
Published online on: 01 April 2005

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Article

Establishment and gene analysis of a cisplatin-resistant cell line, Sa-3R, derived from oral squamous cell carcinoma

Ken Nakatani, Megumi Nakamura, Katsuhiro Uzawa, Takeshi Wada, Naohiko Seki, Hideki Tanzawa, Shigeyuki Fujita
Pages: 709-714
Published online on: 01 April 2005

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Article

E1AF expression is closely correlated with malignant phenotype of tongue squamous cell carcinoma through activation of MT1-MMP gene promoters

Yuri Izumiyama, Yoichi Ohiro, Fumihiro Higashino, Koichi Yoshida, Kazunori Taguchi, Satoru Todo, Takao Kohgo, Yasunori Totsuka, Masanobu Shindoh
Pages: 715-720
Published online on: 01 April 2005

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Article

Regulation of tumor invasion by HOXB13 gene overexpressed in human endometrial cancer

YaWei Zhao, Tsuyoshi Yamashita, Mutsuo Ishikawa
Pages: 721-726
Published online on: 01 April 2005

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Article

The prognostic value of overexpression of Skp2 mRNA in non-small cell lung cancer

Iwao Takanami
Pages: 727-731
Published online on: 01 April 2005

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Article

Early diagnosis and monitoring of superficial transitional cell carcinoma by microsatellite analysis on urine sediment

Takashi Hachisuka, Michihiro Narikiyo, Yukishige Yamada, Hirofumi Ishikawa, Masato Ueno, Hideki Uchida, Ryo Yoriki, Yuichirou Ohigashi, Katsuhiko Miki, Hidetoshi Tamaki, Takashi Mizuno, Yoshiyuki Nakajima
Pages: 733-737
Published online on: 01 April 2005

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Article

Loss of heterozygosity in ductal lavage for breast tumor and the contralateral breast

Yasuhiro Yonekura, Daigo Yamamoto, Homa Okugawa, Kanji Tanaka, Yasuo Kamiyama
Pages: 739-743
Published online on: 01 April 2005

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Article

Role of extracellular matrix in regulation of staurosporine-induced apoptosis in breast cancer cells

F. Vasaturo, C. Malacrino, E. Sallusti, G. Coppotelli, P. Birarelli, A. Giuffrida, L. Albonici, L. Simonelli, A. Modesti, M. Modesti, S. Scarpa
Pages: 745-750
Published online on: 01 April 2005

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Article

PImmunotherapy of renal cell carcinoma with granulocyte macrophage colony stimulating factor and very low dose interleukin-2

Pierpaolo Correale, Stefania Marsili, Marianna Sabatino, Francesco Montagnani, Giorgio Giorgi, Guido Francini
Pages: 751-756
Published online on: 01 April 2005

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Article

Selection of tumor-targeting agents on freshly excised human breast tumors using a phage display library

Girja S. Shukla, David N. Krag
Pages: 757-764
Published online on: 01 April 2005

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Article

Human antibody SC-1 reduces disseminated tumor cells in nude mice with human gastric cancer

Bertram Illert, Christoph Otto, H. Peter Vollmers, Frank Hensel, Arnulf Thiede, Wolfgang Timmermann
Pages: 765-770
Published online on: 01 April 2005

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Article

Comparative genomics on Wnt16 orthologs

Yuriko Katoh, Masaru Katoh
Pages: 771-775
Published online on: 01 April 2005

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Article

Comparative genomics on Wnt7a orthologs

Masuko Katoh, Masaru Katoh
Pages: 777-780
Published online on: 01 April 2005

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Journal Cover
September-2026 Volume 56 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Polyphyllin II inhibits thyroid cancer progression by targeting HRH1 and suppressing Wnt/β‑catenin signaling

Jianwei Sun, Haifeng Liang, Yan Zhang, Ding Ding, Qian Xiang, Mengyang Zheng, Pengyue Zhang
Article Number: 163
Published online on: 23 July 2026

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Review Open Access

Multidimensional molecular mechanisms of drug resistance in breast cancer: Implications for clinical decision‑making and treatment strategies (Review)

Wenya Xu, Shiyao Kang, Shaochen Xin, Yanbin Wu, Yuan Zhao, Miaomiao Sheng
Article Number: 162
Published online on: 22 July 2026

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Review Open Access

XPO1: From basic research to clinical treatment (Review)

Changyan Yang, Jing Zhu, Xiang Zheng, Xiaochen Hou, Jiumei Zhao, Youfu Pan, Yu Tang
Article Number: 161
Published online on: 22 July 2026

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Retraction Open Access

[Retracted] Methylation and intratumoural heterogeneity of 14‑3‑3 σ in oral cancer

Ujjal Kumar Bhawal, Keiichi Tsukinoki, Tomonori Sasahira, Fuyuki Sato, Yusuke Mori, Noriko Muto, Masaru Sugiyama, Hiroki Kuniyasu
Article Number: 160
Published online on: 20 July 2026

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Article Open Access

M2‑TAM‑derived exosomal miR‑491‑3p modulates UBE2D3 and promotes the proliferation, migration and invasion of lung cancer cells

Qiang Zhang, Yungang Sun, Yu Zhuang, Shiwei Xu, Mengxu Yao, Siyang Jiao, Qi Wang, Feng Shao, Xiaoying Zhang
Article Number: 159
Published online on: 17 July 2026

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Correction Open Access

[Corrigendum] Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway

Qingkai Zhang, Xufeng Tao, Shilin Xia, Jialin Qu, Huiyi Song, Jianjun Liu, Hailong Li, Dong Shang
Article Number: 158
Published online on: 15 July 2026

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Article Open Access

TM6SF2 overexpression suppresses the proliferation and promotes apoptosis of human hepatocellular carcinoma cells

Ziyou Huai, Wanying Xue, Xinxiao Jin, Shiyu Peng, Wenqiang Xu, Shujing Li, Huanfeng Hao, Yuanyuan Wang
Article Number: 157
Published online on: 14 July 2026

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Correction Open Access

[Corrigendum] VDAC upregulation and αTAT1‑mediated α‑tubulin acetylation contribute to tanespimycin‑induced apoptosis in Calu‑1 cells

Qilin Wang, Xiangguo Liu
Article Number: 156
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells

Annamaria Spina, Luca Sorvillo, Emilio Chiosi, Antonietta Esposito, Francesca Di Maiolo, Luigi Sapio, Michele Caraglia, Silvio Naviglio
Article Number: 155
Published online on: 06 July 2026

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Article Open Access

Identification of RRM2 as a key regulator of malignant epithelial cells in gastric cancer through single‑cell transcriptomics

Xinzhen Cai, Yun He, Lili Kang, Dongli Zhou, Mengmeng Wang, Tianyu Ma
Article Number: 154
Published online on: 03 July 2026

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Article

Impact of WFDC2 on the biological functions of cervical cancer cells and the regulation of the ERK/NF‑κB signaling pathway

Yanping Zhang, Hongling Zou, Shufeng Deng, Lvling Zou, Mingzhu Xia, Limin Tao
Article Number: 153
Published online on: 01 July 2026

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Cancer‑associated fibroblast‑derived extracellular vesicles promote pancreatic cancer progression via the RAP1B/ANLN axis

Daigo Yoshimori, Mitsuhiro Kudo, Kousuke Ishino, Junji Ueda, Yukako Shintani‑Domoto, Akira Matsushita, Youichi Kawano, Takashi Ono, Takahiro Haruna, Kazuhiko Endo, Akira Hamaguchi, Takenori Fujii, Yoko Kawamoto, Kiyoshi Teduka, Taeko Kitamura, Atsushi Masamune, Akihisa Matsuda, Hiroshi Yoshida, Ryuji Ohashi
Article Number: 176
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Restoration of the tumor‑suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells

Dan Jiang, Lingyao Wang, Tong Zhao, Zhaoyu Zhang, Renxia Zhang, Jingji Jin, Yong Cai, Fei Wang
Article Number: 175
Published online on: 17 August 2026

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Review Open Access

Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review)

Shujing Xia, Xiumei Zhang, Lizhong Tang, Anqi Li, Jianhai Chen, Zhang Tao
Article Number: 174
Published online on: 14 August 2026

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Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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