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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2005 Volume 13 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Aspirin, ibuprofen, and other non-steroidal anti-inflammatory drugs in cancer prevention: A critical review of non-selective COX-2 blockade (Review)

Randall E. Harris, Joanne Beebe-Donk, Hani Doss, Deborah Burr Doss
Pages: 559-583
Published online on: 01 April 2005

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Rat soluble tumor-associated antigens inhibit chemically-induced mammary tumorigenesis in syngeneic rats

George Kossoy, Herzl Ben-Hur, Asher Elhayany, David F. Schneider, Itshak Zusman
Pages: 585-588
Published online on: 01 April 2005

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Article

Pharmacokinetics and adverse reactions of a new liposomal cisplatin (Lipoplatin): Phase I study

George P. Stathopoulos, Teni Boulikas, Maria Vougiouka, George Deliconstantinos, Sotirios Rigatos, Eleftheria Darli, Vasiliki Viliotou, John G. Stathopoulos
Pages: 589-595
Published online on: 01 April 2005

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Expression of thymidine phosphorylase correlates with microvessel density in prostate cancer

Akira Kataoka, Takeshi Yuasa, Susumu Kageyama, Hideaki Iwaki, Kayoko Higuchi, Tsutomu Tanaka, Yusaku Okada, Tatsuhiro Yoshiki
Pages: 597-600
Published online on: 01 April 2005

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Relationship between peroxisome proliferator-activated receptor-γ expression and differentiation of human esophageal squamous cell carcinoma

Takashi Takashima, Yasuhiro Fujiwara, Masaki Hamaguchi, Eiji Sasaki, Kazunari Tominaga, Toshio Watanabe, Nobuhide Oshitani, Kazuhide Higuchi, Tetsuo Arakawa
Pages: 601-606
Published online on: 01 April 2005

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Article

Changes of histological and biological features by serial passages in a human adenoid cystic carcinoma line transplantable in nude mice

Susumu Hashitani, Kazuma Noguchi, Yukiyo Manno, Kuniyasu Moridera, Kazuki Takaoka, Norihiko Nishimura, Hiromitsu Kishimoto, Kazunari Sakurai, Masahiro Urade
Pages: 607-612
Published online on: 01 April 2005

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Article

Expression of cell adhesion molecules and chemokine receptors: Angioinvasiveness in nasal NK/T-cell lymphoma

Angen Liu, Shin-ichi Nakatsuka, Woo-Ick Yang, Shizuo Kojya, Katsuyuki Aozasa
Pages: 613-620
Published online on: 01 April 2005

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Article

Thymidine phosphorylase expression and efficacy of adjuvant doxifluridine in advanced colorectal cancer patients

Shiro Hasegawa, Kazuhiro Seike, Keiji Koda, Nobuhiro Takiguchi, Kenji Oda, Rumiko Hasegawa, Masaru Miyazaki
Pages: 621-626
Published online on: 01 April 2005

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Article

Venous thromboembolism in colorectal cancer patients with central venous catheters for 5-FU infusion-based pharmacokinetic modulating chemotherapy

Reigetsu Yoshikawa, Hidenori Yanagi, Masafumi Noda, Hiroki Ikeuchi, Hiroki Nakano, Makoto Gega, Kiyoshi Tsukamoto, Tsutomu Oshima, Takashi Inoue, Yoshinori Fujiwara, Yasutsugu Shoji, Takatoshi Sakaki, Satoshi Higasa, Tomoko Hashimoto-Tamaoki, Takehira Yamamura
Pages: 627-632
Published online on: 01 April 2005

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Detection of Her2/neu, c-MYC and ZNF217 gene amplification during breast cancer progression using fluorescence in situ hybridization

Masayuki Shimada, Johji Imura, Takazumi Kozaki, Takahiro Fujimori, Shuichi Asakawa, Nobuyoshi Shimizu, Ryuji Kawaguchi
Pages: 633-641
Published online on: 01 April 2005

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Article

Expression of c-kit (CD117) in neuroendocrine tumours - a target for therapy?

Virginia Kostoula, Korsa Khan, Kay Savage, Mark Stubbs, Alberto Quaglia, Amar P. Dhillon, Daniel Hochhauser, Martyn E. Caplin
Pages: 643-647
Published online on: 01 April 2005

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Atypical lipomatous tumor with rare structural rearrangements involving chromosomes 8 and 12

Malin Nilsson, Henryk Domanski, Fredrik Mertens, Nils Mandahl
Pages: 649-652
Published online on: 01 April 2005

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Article

Antiproliferation effects of ponicidin on human myeloid leukemia cells in vitro

Jia-Jun Liu, Ren-Wei Huang, Dong-Jun Lin, Xiang-Yuan Wu, Qu Lin, Jun Peng, Xianglin Pan, Yu-Qin Song, Mao-hong Zhang, Ming Hou, Feng Chen
Pages: 653-657
Published online on: 01 April 2005

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Article

Inhibition of cell cycle and induction of apoptosis by sulforaphane in cell lines carrying various inherited BRCA1 mutations

Irena Misiewicz, Agata Kozar, Katarzyna Skupinska, Elzbieta Kowalska, Jan Lubinski, Teresa Kasprzycka-Guttman
Pages: 659-665
Published online on: 01 April 2005

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Long-term administration of low-dose cisplatin plus 5-fluorouracil prolongs the postoperative survival of patients with esophageal cancer

Atsushi Shiozaki, Hisakazu Yamagishi, Hirosumi Itoi, Hitoshi Fujiwara, Shojiro Kikuchi, Kazuma Okamoto, Daisuke Ichikawa, Nobuaki Fuji, Toshiya Ochiai, Teruhisa Sonoyama, Yuji Ueda
Pages: 667-672
Published online on: 01 April 2005

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Article

Aberrant expression of HOX genes in human invasive breast carcinoma

Kokonoe Makiyama, Jun-ichi Hamada, Minoru Takada, Katsuhiko Murakawa, Yoko Takahashi, Mitsuhiro Tada, Eiji Tamoto, Gaku Shindo, Akihiro Matsunaga, Ken-ichi Teramoto, Kazuteru Komuro, Satoshi Kondo, Hiroyuki Katoh, Takao Koike, Tetsuya Moriuchi
Pages: 673-679
Published online on: 01 April 2005

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Article

Irinotecan combined or alternated with bolus 5-fluorouracil and folinic acid versus the Mayo Clinic regimen in the first-line therapy of advanced colorectal cancer

Ullrich Graeven, Karsten Ridwelski, Maja Artandi, Pilar Espana, Jürgen Schölmerich, Adolfo M. Rosales, Göran CARLSSON, Markus Borner, Blandine Boussard, Wolff Schmiegel
Pages: 681-688
Published online on: 01 April 2005

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Article

Pro-neoangiogenic cytokines (VEGF and bFGF) and anemia in solid tumor patients

Camillo Porta, Ilaria Imarisio, Mara De Amici, Lucia Bonomi, Chiara Paglino, Elisa Biscaldi, Matteo Zimatore, Andrea Sartore-Bianchi, Marco Danova, Remigio Moratti, Alberto Riccardi
Pages: 689-695
Published online on: 01 April 2005

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Article

Predictive value of COX-2 for the effect of chemoradiotherapy on esophageal squamous cell carcinoma

Hiroyuki Takatori, Shoji Natsugoe, Hiroshi Okumura, Masataka Matsumoto, Sumiya Ishigami, Tetsuhiro Owaki, Takashi Aikou
Pages: 697-701
Published online on: 01 April 2005

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Article

Infrequent mutation of the human envoplakin gene is closely linked to the tylosis oesophageal cancer locus in sporadic oesophageal squamous cell carcinomas

Takeshi Iwaya, Chihaya Maesawa, Toshimoto Kimura, Satoshi Ogasawara, Kenichro Ikeda, Yusuke Kimura, Yoshinori Noda, Kaoru Ishida, Nobuhiro Sato, Kazuyoshi Saito, Tomoyuki Masuda
Pages: 703-707
Published online on: 01 April 2005

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Article

Establishment and gene analysis of a cisplatin-resistant cell line, Sa-3R, derived from oral squamous cell carcinoma

Ken Nakatani, Megumi Nakamura, Katsuhiro Uzawa, Takeshi Wada, Naohiko Seki, Hideki Tanzawa, Shigeyuki Fujita
Pages: 709-714
Published online on: 01 April 2005

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Article

E1AF expression is closely correlated with malignant phenotype of tongue squamous cell carcinoma through activation of MT1-MMP gene promoters

Yuri Izumiyama, Yoichi Ohiro, Fumihiro Higashino, Koichi Yoshida, Kazunori Taguchi, Satoru Todo, Takao Kohgo, Yasunori Totsuka, Masanobu Shindoh
Pages: 715-720
Published online on: 01 April 2005

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Article

Regulation of tumor invasion by HOXB13 gene overexpressed in human endometrial cancer

YaWei Zhao, Tsuyoshi Yamashita, Mutsuo Ishikawa
Pages: 721-726
Published online on: 01 April 2005

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Article

The prognostic value of overexpression of Skp2 mRNA in non-small cell lung cancer

Iwao Takanami
Pages: 727-731
Published online on: 01 April 2005

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Article

Early diagnosis and monitoring of superficial transitional cell carcinoma by microsatellite analysis on urine sediment

Takashi Hachisuka, Michihiro Narikiyo, Yukishige Yamada, Hirofumi Ishikawa, Masato Ueno, Hideki Uchida, Ryo Yoriki, Yuichirou Ohigashi, Katsuhiko Miki, Hidetoshi Tamaki, Takashi Mizuno, Yoshiyuki Nakajima
Pages: 733-737
Published online on: 01 April 2005

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Article

Loss of heterozygosity in ductal lavage for breast tumor and the contralateral breast

Yasuhiro Yonekura, Daigo Yamamoto, Homa Okugawa, Kanji Tanaka, Yasuo Kamiyama
Pages: 739-743
Published online on: 01 April 2005

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Article

Role of extracellular matrix in regulation of staurosporine-induced apoptosis in breast cancer cells

F. Vasaturo, C. Malacrino, E. Sallusti, G. Coppotelli, P. Birarelli, A. Giuffrida, L. Albonici, L. Simonelli, A. Modesti, M. Modesti, S. Scarpa
Pages: 745-750
Published online on: 01 April 2005

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Article

PImmunotherapy of renal cell carcinoma with granulocyte macrophage colony stimulating factor and very low dose interleukin-2

Pierpaolo Correale, Stefania Marsili, Marianna Sabatino, Francesco Montagnani, Giorgio Giorgi, Guido Francini
Pages: 751-756
Published online on: 01 April 2005

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Article

Selection of tumor-targeting agents on freshly excised human breast tumors using a phage display library

Girja S. Shukla, David N. Krag
Pages: 757-764
Published online on: 01 April 2005

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Article

Human antibody SC-1 reduces disseminated tumor cells in nude mice with human gastric cancer

Bertram Illert, Christoph Otto, H. Peter Vollmers, Frank Hensel, Arnulf Thiede, Wolfgang Timmermann
Pages: 765-770
Published online on: 01 April 2005

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Article

Comparative genomics on Wnt16 orthologs

Yuriko Katoh, Masaru Katoh
Pages: 771-775
Published online on: 01 April 2005

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Article

Comparative genomics on Wnt7a orthologs

Masuko Katoh, Masaru Katoh
Pages: 777-780
Published online on: 01 April 2005

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Exploring the role of disulfidptosis‑related signatures in immune microenvironment, prognosis and therapeutic strategies of cholangiocarcinoma

Yue Chen, Jun Wu, Danxia Zhu, Lu Jiang, Jian Wang, Dachuan Zhang, Wenting He
Article Number: 37
Published online on: 02 January 2026

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Correction Open Access

[Corrigendum] Isolinderalactone enhances the inhibition of SOCS3 on STAT3 activity by decreasing miR‑30c in breast cancer

Meng-Chi Yen, Ying-Chu Shih, Ya-Ling Hsu, En-Shyh Lin, Yi-Shiuan Lin, Eing-Mei Tsai, Ya-Wen Ho, Ming-Feng Hou, Po-Lin Kuo
Article Number: 36
Published online on: 22 December 2025

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Article Open Access

Hypoxia‑mediated Krebs von den Lungen‑6 expression in breast cancer: Implications for tumor invasion and metastasis

Taisei Ichihara, Yoshihiro Hayashi, Takuya Sato, Mitsuko Iguchi, Makoto Toi, Hironaga Satake, Ichiro Murakami
Article Number: 35
Published online on: 19 December 2025

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Retraction Open Access

[Retracted] β‑elemene decreases cell invasion by upregulating E‑cadherin expression in MCF‑7 human breast cancer cells

Xian Zhang, Yang Zhang, Yinghua Li
Article Number: 34
Published online on: 18 December 2025

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Review Open Access

Research progress on the regulation of ferroptosis in NPC (Review)

Shuai Bai, Yanjie Guo, Jingling Qiang, Qiangfang Dai, Yanling Yang
Article Number: 33
Published online on: 18 December 2025

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Retraction Open Access

[Retracted] Platelet‑derived growth factor BB mediates the glioma‑induced migration of bone marrow‑derived mesenchymal stem cells by promoting the expression of vascular cell adhesion molecule‑1 through the PI3K, P38 MAPK and NF‑κB pathways

Yi Hu, Peng Cheng, Jiang-Chun Ma, Yi-Xue Xue, Yun-Hui Liu
Article Number: 32
Published online on: 08 December 2025

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Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício De Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑De‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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