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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2005 Volume 14 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Dual FISH analysis of benign and malignant tumors of the salivary glands and paranasal sinuses

Karl Götte, Stefan Ganssmann, Annette Affolter, Carsten Schäfer, Frank Riedel, Norbert Arens, Sonja Finger, Karl Hörmann
Pages: 1103-1107
Published online on: 01 November 2005

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Article

Co-expressed type of ER and HER2 protein as a predictive factor in determining resistance to antiestrogen therapy in patients with ER-positive and HER2-positive breast cancer

Jun Horiguchi, Yukio Koibuchi, Kotaro Iijima, Takashi Yoshida, Daisuke Takata, Nana Rokutanda, Rin Nagaoka, Tetsunari Oyama, Yuichi Iino, Yasuo Morishita
Pages: 1109-1116
Published online on: 01 November 2005

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Article

Effect of bilateral oophorectomy on mammary tumor formation in BRCA1 mutant mice

Richard Bachelier, Xiaoling Xu, Cuiling Li, Wenhui Qiao, Priscilla A. Furth, Ronald A. Lubet, Chu-Xia Deng
Pages: 1117-1120
Published online on: 01 November 2005

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Article

Cell proliferation of bulky cervical squamous cell carcinoma is strongly associated with a paracrine tissue-specific growth factor(s)

Tetsuji Tanaka, Saori Toujima, Tomoko Utsunomiya, Tao Bai, Hirotoshi Utsunomiya, Ichiro Mori, Kazunori Yukawa, Naohiko Umesaki
Pages: 1121-1126
Published online on: 01 November 2005

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Article

A clinical and immunohistochemical study on gastrointestinal mesenchymal tumor (GIMT): RCAS1 as a predictor for recurrence of GIMT

Akihiko Naito, Michihiro Narikiyo, Yukishige Yamada, Masatoh Ueno, Kiyoshi Kamada, Takashi Hachisuka, Ryo Yoriki, Takashi Mizuno, Yoshiyuki Nakajima
Pages: 1127-1132
Published online on: 01 November 2005

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Article

Microsatellite instability and proliferating activity in sinonasal carcinoma: Molecular genetic and immunohistochemical comparison with oral squamous cell carcinoma

Hideoki Uryu, Yoshinao Oda, Hideki Shiratsuchi, Shinya Oda, Hidetaka Yamamoto, Shizuo Komune, Masazumi Tsuneyoshi
Pages: 1133-1142
Published online on: 01 November 2005

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Article

Induction of apoptosis in human salivary gland tumor cells by anti-NCAM antibody

Masakatsu Fukuda, Yuko Horiuchi, Yuka Oku, Mari Ishikawa, Noriyuki Suka, Seiji Suzuki, Kaoru Kusama, Hideaki Sakashita
Pages: 1143-1149
Published online on: 01 November 2005

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Article

No evidence of correlation between the single nucleotide polymorphism of DNMT3B promoter and gastric cancer risk in a Japanese population

Phyu Phyu Aung, Shunji Matsumura, Kazuya Kuraoka, Kyoko Kunimitsu, Kazuhiro Yoshida, Keisuke Matsusaki, Hirofumi Nakayama, Wataru Yasui
Pages: 1151-1154
Published online on: 01 November 2005

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Article

E1B-deleted adenovirus replicates in p53-deficient lung cancer cells due to the absence of apoptosis

Naoki Harada, Yoshimasa Maniwa, Masahiro Yoshimura, Masao Nagata, Hirofumi Hamada, Kouichi Yokono, Yutaka Okita
Pages: 1155-1163
Published online on: 01 November 2005

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Article

Recurrence and 5-FU sensitivity of stage III/Dukes' C colorectal cancer with occult neoplastic cells in lymph node sinuses

Masaya Mukai, Shinkichi Sato, Hiromi Ninomiya, Kanako Wakui, Nobukazu Komatsu, Kazutoshi Tsuchiya, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1165-1169
Published online on: 01 November 2005

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Article

Recurrence and 5-FU sensitivity of stage II/Dukes' B colorectal cancer with occult neoplastic cells in lymph node sinuses

Masaya Mukai, Shinkichi Sato, Hiromi Ninomiya, Kanako Wakui, Nobukazu Komatsu, Kazutoshi Tsuchiya, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1171-1176
Published online on: 01 November 2005

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Article

Chemoradiotherapy for T3 and T4 squamous cell carcinoma of the esophagus using low-dose FP and radiation: A preliminary report

Yoshinori Fujiwara, Norihiko Kamikonya, Takashi Inoue, Kenji Koishi, Reigetsu Yoshikawa, Koji Nakao, Ryuuichirou Yagyu, Manabu Nishiwaki, Masayuki Fujiwara, Shoudou Kojima, Kazuhiko Nakagawa, Takehira Yamamura
Pages: 1177-1182
Published online on: 01 November 2005

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Article

Comparative study of renal cell carcinoma by CGH, multicolor-FISH and conventional cytogenic banding analysis

Jimsgene Sanjmyatav, Joerg Schubert, Kerstin Junker
Pages: 1183-1187
Published online on: 01 November 2005

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Article

Gene expression profiling of the bone marrow mononuclear cells from patients with myelodysplastic syndrome

Jun Qian, Zixing Chen, Wei Wang, Jiannong Cen, Yongquan Xue
Pages: 1189-1197
Published online on: 01 November 2005

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Article

Tenascin C and epidermal growth factor receptor as markers of circulating tumoral cells in bladder and colon cancer

Paola Gazzaniga, Italo Nofroni, Orietta Gandini, Ida Silvestri, Luigi Frati, Anna Maria Aglianò, Angela Gradilone
Pages: 1199-1202
Published online on: 01 November 2005

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Article

Development of an HT29 liver metastases model in nude rats

Frédéric Marchal, N'guyen Tran, Sophie Marchal, Agnès Leroux, Christian Marchal, Lina Bolotine, François Guillemin, Jean Pierre Villemot
Pages: 1203-1207
Published online on: 01 November 2005

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Article

18FDG-positron emission tomography in post treatment evaluation of residual mass in Hodgkin's lymphoma: Long-term results

Luigi Rigacci, Antonio Castagnoli, Catia Dini, Andrea Carpaneto, Maria Matteini, Renato Alterini, Valentina Carrai, Luca Nassi, Franco Bernardi, Cesco Pieroni, Alberto Bosi
Pages: 1209-1214
Published online on: 01 November 2005

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Article

Enhancement of susceptibility to Fas-mediated apoptosis in HL-60 cells through down-regulation of cellular FLICE-inhibitory protein by phosphatidylinositol 3-kinase inhibitors

Gen Kondo, Masayasu Iwase, Hitoshi Watanabe, Makiko Uchida, Sayaka Takaoka, Masaru Ohashi, Daisuke Ito, Masao Nagumo
Pages: 1215-1222
Published online on: 01 November 2005

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Article

Immunohistochemical demonstration of fluoropyrimidine-metabolizing enzymes in various types of cancer

Shingo Kamoshida, Kazuya Shiogama, Ryoichi Shimomura, Ken-Ichi Inada, Yoichi Sakurai, Masahiro Ochiai, Hiroshi Matuoka, Kotaro Maeda, Yutaka Tsutsumi
Pages: 1223-1230
Published online on: 01 November 2005

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Article

Classification of neural differentiation-associated genes in P19 embryonal carcinoma cells by their expression patterns induced after cell aggregation and/or retinoic acid treatment

Sayaka Teramoto, Fumiko Kihara-Negishi, Takuya Sakurai, Toshiyuki Yamada, Tomoko Hashimoto-Tamaoki, Shinri Tamura, Seiichi Kohno, Tsuneyuki Oikawa
Pages: 1231-1238
Published online on: 01 November 2005

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Article

Prognostic value of human papillomavirus in the survival of head and neck cancer patients: An overview of the evidence

Nicolas F. Schlecht
Pages: 1239-1247
Published online on: 01 November 2005

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Article

Caspase-8 is scarcely silenced and its activity is well correlated with the anticancer effect of tumor necrosis factor-related apoptosis-inducing ligand in gastric cancer cells

Isao Kanehara, Bunzo Nakata, Kosei Hirakawa
Pages: 1249-1253
Published online on: 01 November 2005

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Article

Analysis of local recurrence after breast conservative treatment for invasive breast cancer: A single institution cohort

J. Pomp, J. Blom, A. H. Zwinderman, S. H. Sastrowijoto, C. van Krimpen
Pages: 1255-1261
Published online on: 01 November 2005

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Article

Identifying genes with differential expression in gemcitabine-resistant pancreatic cancer cells using comprehensive transcriptome analysis

Yousuke Nakai, Motoyuki Otsuka, Yujin Hoshida, Minoru Tada, Yutaka Komatsu, Takao Kawabe, Masao Omata
Pages: 1263-1267
Published online on: 01 November 2005

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Article

CD4+CD25+ regulatory T cells in the peripheral blood of patients with breast cancer and non-small cell lung cancer

Riki Okita, Toshiaki Saeki, Shigemitsu Takashima, Yoshiyuki Yamaguchi, Tetsuya Toge
Pages: 1269-1273
Published online on: 01 November 2005

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Article

Down-regulation of O6-methylguanine-DNA methyltransferase gene expression in gliomas by platinum compounds

Satoshi Tanaka, Ikuo Kobayashi, Satoshi Utsuki, Hidehiro Oka, Yoshie Yasui, Kiyotaka Fujii
Pages: 1275-1280
Published online on: 01 November 2005

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Article

Establishment and characterization of a cisplatin-resistant oral squamous cell carcinoma cell line, H-1R

Megumi Nakamura, Ken Nakatani, Katsuhiro Uzawa, Kanae Ono, Hisako Uesugi, Katsunori Ogawara, Masashi Shiiba, Hiroki Bukawa, Hidetaka Yokoe, Takeshi Wada, Shigeyuki Fujita, Hideki Tanzawa
Pages: 1281-1286
Published online on: 01 November 2005

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Article

C2-ceramide exhibits antiproliferative activity and potently induces apoptosis in endometrial carcinoma

Noriyuki Takai, Tami Ueda, Yasushi Kawano, Masakazu Nishida, Kaei Nasu, Hisashi Narahara
Pages: 1287-1291
Published online on: 01 November 2005

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Article

Identification of candidate radioresistant genes in human squamous cell carcinoma cells through gene expression analysis using DNA microarrays

Morihiro Higo, Katsuhiro Uzawa, Yukinao Kouzu, Hiroki Bukawa, Yoshinori Nimura, Naohiko Seki, Hideki Tanzawa
Pages: 1293-1298
Published online on: 01 November 2005

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Article

Quercetin induces gadd45 expression through a p53-independent pathway

Tatsushi Yoshida, Ayaka Maeda, Mano Horinaka, Takumi Shiraishi, Susumu Nakata, Miki Wakada, Shingo Yogosawa, Toshiyuki Sakai
Pages: 1299-1303
Published online on: 01 November 2005

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Article

Mitochondria-independent induction of Fas-mediated apoptosis by MSSP

Jun Nomura, Ken-Ichi Matsumoto, Sanae M.M. Iguchi-Ariga, Hiroyoshi Ariga
Pages: 1305-1309
Published online on: 01 November 2005

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Article

Targeting of X-linked inhibitor of apoptosis protein or survivin by short interfering RNAs sensitize hepatoma cells to TNF-related apoptosis-inducing ligand- and chemotherapeutic agent-induced cell death

Yumi Yamaguchi, Katsuya Shiraki, Hiroyuki Fuke, Tomoko Inoue, Kazumi Miyashita, Yutaka Yamanaka, Yukiko Saitou, Kazushi Sugimoto, Takeshi Nakano
Pages: 1311-1316
Published online on: 01 November 2005

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Article

Effects of tamoxifen and soluble tumor-associated antigens on ovarian structure in mammary tumor-bearing rats

George Kossoy, Herzl Ben-Hur, Asher Elhayany, David F. Schneider, Nadja Kossoy, Itshak Zusman
Pages: 1317-1321
Published online on: 01 November 2005

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Article

Identification of reproducible low mass SELDI protein profiles specific to cisplatin resistance in human ovarian cancer cells

Richard A. Britten, Carrie Hardy, Antonia Vlahou, Betsy Gregory, P. Shankar Giri, Richard Drake
Pages: 1323-1330
Published online on: 01 November 2005

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Article

In vitro studies of the dry fruit of Chinese fan palm Livistona chinensis

Susan Cheung, Joseph Tai
Pages: 1331-1336
Published online on: 01 November 2005

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Article

Targeted adriamycin delivery to MXT-B2 metastatic mammary carcinoma cells by transferrin liposomes: Effect of adriamycin ADR-to-lipid ratio

Lluis A. Lopez-Barcons, Dolores Polo, Ana Llorens, Francesca Reig, Angels Fabra
Pages: 1337-1343
Published online on: 01 November 2005

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Article

Antioxidant and anti-inflammatory properties of ESSIAC and Flor-essence

Susan Cheung, Kye-Taek Lim, Joseph Tai
Pages: 1345-1350
Published online on: 01 November 2005

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Article

Comparative genomics on SLIT1, SLIT2, and SLIT3 orthologs

Yuriko Katoh, Masaru Katoh
Pages: 1351-1355
Published online on: 01 November 2005

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Article

The pyrrolo-1,5-benzoxazepine, PBOX-6, inhibits the growth of breast cancer cells in vitro independent of estrogen receptor status and inhibits breast tumour growth in vivo

Lisa M. Greene, Marina Fleeton, Jude Mulligan, Chikkanna Gowda, Brian J. Sheahan, Gregory J. Atkins, Giuseppe Campiani, Vito Nacci, Mark Lawler, D. Clive Williams, Daniela M. Zisterer
Pages: 1357-1363
Published online on: 01 November 2005

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Article

Combination effects of irradiation and irinotecan on cervical squamous cell carcinoma cells in vitro

Tetsuji Tanaka, Kazunori Yukawa, Naohiko Umesaki
Pages: 1365-1369
Published online on: 01 November 2005

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Article

Enhanced expression of the secreted form of clusterin following neoadjuvant hormonal therapy as a prognostic predictor in patients undergoing radical prostatectomy for prostate cance

Hideaki Miyake, Kazuki Yamanaka, Mototsugu Muramaki, Toshifumi Kurahashi, Martin Gleave, Isao Hara
Pages: 1371-1375
Published online on: 01 November 2005

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Review

Minimal residual disease as the target for immunotherapy and gene therapy of cancer (Review)

Jan Bubeník, Jana Símová
Pages: 1377-1380
Published online on: 01 November 2005

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Article

Comparative genomics on ROR1 and ROR2 orthologs

Masuko Katoh, Masaru Katoh
Pages: 1381-1384
Published online on: 01 November 2005

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Article

Identification of carotenoids in ovarian tissue in women

Ewa Czeczuga-Semeniuk, Slawomir Wolczynski
Pages: 1385-1392
Published online on: 01 November 2005

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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