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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2006 Volume 16 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Expression of COX-2 and steroid converting enzymes in breast cancer

Cecilia Gunnarsson, Agneta Jansson, Birgitta Holmlund, Lilianne Ferraud, Bo Nordenskjöld, Lars Erik Rutqvist, Lambert Skoog, Olle Stål
Pages: 219-224
Published online on: 01 August 2006

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Article

A cytogenetic analysis in two cases of malignant peripheral nerve sheath tumor showing hypodiploid karyotype

Masako Ishiguro, Hiroshi Iwasaki, Morishige Takeshita, Yumiko Hirose, Yasuhiko Kaneko
Pages: 225-232
Published online on: 01 August 2006

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Review

Dose and outcome: The hurdle of neutropenia (Review)

Maurizio Marangolo, Carmelo Bengala, Pier Franco Conte, Marco Danova, Paolo Pronzato, Giovanni Rosti, Paola Sagrada
Pages: 233-248
Published online on: 01 August 2006

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Article

Expression of type I interferon receptor as a predictor of clinical response to interferon-α therapy of gastrointestinal cancers

Hideo Ota, Hiroaki Nagano, Yuichiro Doki, Mitsugu Sekimoto, Motoi Kondo, Hiroshi Wada, Masato Nakamura, Takehiro Noda, Bazarragchaa Damdinsuren, Shigeru Marubashi, Atsushi Miyamoto, Yutaka Takeda, Keizo Dono, Koji Umeshita, Shoji Nakamori, Kenichi Wakasa, Masato Sakon, Morito Monden
Pages: 249-255
Published online on: 01 August 2006

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Article

Lactoferrin immunoexpression in endometrial carcinomas: relationships with sex steroid hormone receptors (ER and PR), proliferation indices (Ki-67 and AgNOR) and survival

Giuseppe Giuffrè, Francesco Arena, Rosa Scarfì, Angela Simone, Paolo Todaro, Giovanni Tuccari
Pages: 257-263
Published online on: 01 August 2006

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Article

Establishment and characterization of a new cell line, FRTK-1, derived from human malignant rhabdoid tumor of the kidney, with overexpression of epidermal growth factor receptor and cyclooxygenase-2

Michiyuki Hakozaki, Hiroshi Hojo, Michiko Sato, Yasuhiko Kaneko, Naoki Watanabe, Shinichi Kikuchi, Masafumi Abe
Pages: 265-271
Published online on: 01 August 2006

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Article

Chemopreventive alteration of the cell-cell adhesion in head and neck squamous cell cancer

Ramin Naim, Ray C. Chang, Johannes Schultz, Karl Hormann
Pages: 273-277
Published online on: 01 August 2006

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Article

Thymidine phosphorylase expression as a prognostic marker for predicting recurrence in primary superficial bladder cancer

Shigeyuki Aoki, Yoshiaki Yamada, Kogenta Nakamura, Tomohiro Taki, Motoi Tobiume, Nobuaki Honda
Pages: 279-284
Published online on: 01 August 2006

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Article

Connexin 43 transfection in basaloid squamous cell carcinoma cells

Kaori Shima, Takashi Muramatsu, Yoshihiro Abiko, Yuji Yamaoka, Hodaka Sasaki, Masaki Shimono
Pages: 285-288
Published online on: 01 August 2006

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Article

Down-regulation of caveolin-1 in mouse Lewis lung cancer P29 is a causal factor for the malignant properties in a high-metastatic subline

Qing Zhang, Keiko Furukawa, Ho-Hsiang Chen, Reiko Fujinawa, Yasunori Kozutsumi, Akemi Suzuki, Takeshi Urano, Koichi Furukawa
Pages: 289-294
Published online on: 01 August 2006

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Article

Cutaneous dermoid cyst: Cytokeratin and filaggrin expression suggesting differentiation towards follicular infundibulum and mature sebaceous gland

Ichiro Kurokawa, Keisuke Nishimura, Arata Hakamada, Ken-ichi Isoda, Kei-ichi Yamanaka, Hitoshi Mizutani, Airo Tsubura
Pages: 295-299
Published online on: 01 August 2006

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Article

Amplification of hTERT and hTERC genes in leukemic cells with high expression and activity of telomerase

Tomasz Nowak, Danuta Januszkiewicz, Mariola Zawada, Monika Pernak, Krzysztof Lewandowski, Jolanta Rembowska, Karina Nowicka, Przemyslaw Mankowski, Jerzy Nowak
Pages: 301-305
Published online on: 01 August 2006

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Article

Fas-mediated pathway and apoptosis in normal cervix, cervical intraepithelial neoplasia and cervical squamous cancer

Jian-hong Zhou, Huai-zeng Chen, Feng Ye, Wei-guo Lu, Xing Xie
Pages: 307-311
Published online on: 01 August 2006

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Article

Matrigel influences morphology and cathepsin B distribution of prostate cancer PC3 cells

Purva Gopal, Reiaz U. Rehman, Kanwarjeet S. Chadha, Mengshing Qiu, Rita Colella
Pages: 313-320
Published online on: 01 August 2006

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Article

Inflammatory infiltration, fibrosis, necrosis and mucinous content in relation to clinicopathological and molecular factors in rectal cancers with or without preoperative radiotherapy

Annica Knutsen, Gunnar Adell, Xiao-Feng Sun
Pages: 321-327
Published online on: 01 August 2006

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Article

Prognostic role of the tumor-associated tissue inflammatory reaction in transitional bladder cell carcinoma

Tommaso Cai, Gabriella Nesi, Vieri Boddi, Sandra Mazzoli, Maurizio Dal Canto, Riccardo Bartoletti
Pages: 329-334
Published online on: 01 August 2006

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Article

Expression of galectin-3 in gonads and gonadal sex cord stromal and germ cell tumors

Mojgan Devouassoux-Shisheboran, Catherine Deschildre, Claire Mauduit, Gérard Berger, Frédérique Mejean-Lebreton, Raymonde Bouvier, Jean Pierre Droz, Patrick Fénichel, Mohamed Benahmed
Pages: 335-340
Published online on: 01 August 2006

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Article

Nutraceutical inhibitors of urokinase: Potential applications in prostate cancer prevention and treatment

Jerzy Jankun, Steven H. Selman, Jacek Aniola, Ewa Skrzypczak-Jankun
Pages: 341-346
Published online on: 01 August 2006

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Article

Clinical added-value of 18FDG PET in neuroendocrine-merkel cell carcinoma

Tarik Belhocine, Gerald E. Pierard, Janos Frühling, Gaëtan Letesson, Stephanie Bolle, Roland Hustinx, Jean-Louis Dargent, Patrick Flamen, Pierre Rigo
Pages: 347-352
Published online on: 01 August 2006

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Article

Genetic analysis of Caveolin-1 and eNOS genes in colorectal cancer

Manuel Chaves Conde, Reposo Ramirez-Lorca, Jose Miguel Esteban Lopez-Jamar, Eva Molero, Juan Andres Ramírez-Armengol, Jose Andrés Moreno Nogueira, Manuel Hidalgo Pascual, Agustin Ruiz, Carlos García Martín-Cordova, Luis Miguel Real, Jose Luis Royo
Pages: 353-359
Published online on: 01 August 2006

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Article

Pharmacokinetics of S-1 in patients with peritoneal dissemination of gastric cancer

Takashi Oshima, Roppei Yamada, Shinsuke Hatori, Chikara Kunisaki, Toshio Imada
Pages: 361-366
Published online on: 01 August 2006

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Article

Synergistic effects of granulocyte-colony stimulating factor and macrophage-colony stimulating factor on recovery of donor hematopoietic cells in allogeneic bone marrow transplantation

Yuming Zhang, Yasushi Adachi, Yasuhiro Suzuki, Keizo Minamino, Masayoshi Iwasaki, Keiji Nakano, Yasushi Koike, Hiromi Mukaide, Akio Shigematsu, Naoko Kiriyama, Chunfu Li, Susumu Ikehara
Pages: 367-371
Published online on: 01 August 2006

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Article

The autocrine effect of activin A on human ovarian clear cell adenocarcinoma cells

Yasushi Mabuchi, Mareo Yamoto, Sawako Minami, Naohiko Umesaki
Pages: 373-379
Published online on: 01 August 2006

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Article

Relation between cytokine promoter gene polymorphism and toxicity of 5-fluorouracil plus cisplatin chemotherapy

Kazuhiko Sakamoto, Masaaki Oka, Shigehumi Yoshino, Shoichi Hazama, Toshihiro Abe, Naoko Okayama, Yuji Hinoda
Pages: 381-387
Published online on: 01 August 2006

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Article

Survivin downregulation by siRNA sensitizes human hepatoma cells to TRAIL-induced apoptosis

Kazuhiko Nakao, Keisuke Hamasaki, Tatsuki Ichikawa, Kazuhiko Arima, Katsumi Eguchi, Nobuko Ishii
Pages: 389-392
Published online on: 01 August 2006

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Article

Trastuzumab in combination with gemcitabine and vinorelbine as second-line therapy for HER-2/neu overexpressing metastatic breast cancer

Alessandro Morabito, Raffaele Longo, Domenico Gattuso, Guido Carillio, Cristian Massaccesi, Luigi Mariani, Paola Bonginelli, Scolastica Amici, Livia De Sio, Massimo Fanelli, Francesco Torino, Maurizio Bonsignori, Giampietro Gasparini
Pages: 393-398
Published online on: 01 August 2006

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Article

Different expression patterns of intact forms of squamous cell carcinoma antigens between normal and malignant cervical squamous epithelial tissues: Nondenaturing polyacrylamide gel electrophoretic analysis

Shugo Nawata, Akihiro Murakami, Mayumi Torii, Tatsushi Nakagawa, Kotaro Sueoka, Osamu Takeda, Yoshinori Suminami, Kazuyuki Nakamura, Hiroshi Kato, Norihiro Sugino
Pages: 399-404
Published online on: 01 August 2006

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Article

Prospective study on the recurrence/metastasis of stage II/III colorectal cancer and gastric cancer associated with occult neoplastic cells in lymph node sinuses: Three-year interim results

Masaya Mukai, Takayuki Tajima, Shinkichi Sato, Hiromi Ninomiya, Kanako Wakui, Nobukazu Komatsu, Kazutoshi Tsuchiya, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 405-410
Published online on: 01 August 2006

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Article

Detection of lymph node micrometastasis in pN0 early gastric cancer: Efficacy of duplex RT-PCR with MUC2 and TFF1 in mucosal cancer

Hiromichi Sonoda, Kazuo Yamamoto, Ryoji Kushima, Hiroshi Yamamoto, Hiroyuki Naitoh, Hidetoshi Okabe, Tohru Tani
Pages: 411-416
Published online on: 01 August 2006

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Article

Three distinct regions of deletion on 13q in squamous cell carcinoma of the larynx

Agnieszka Stembalska, Nikolaus Blin, David Ramsey, Maria M. Sasiadek
Pages: 417-421
Published online on: 01 August 2006

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Article

Telomerase inhibition by an siRNA directed against hTERT leads to telomere attrition in HT29 cells

Patrícia de Souza Nascimento, Gilda Alves, Wolfgang Fiedler
Pages: 423-428
Published online on: 01 August 2006

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Article

Promoter methylation status of the MGMT, hMLH1, and CDKN2A/p16 genes in non-neoplastic mucosa of patients with and without colorectal adenomas

Chuanzhong Ye, Martha J. Shrubsole, Qiuyin Cai, Reid Ness, William M. Grady, Walter Smalley, Hui Cai, Kay Washington, Wei Zheng
Pages: 429-435
Published online on: 01 August 2006

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Journal Cover
June-2026 Volume 55 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

E3 ubiquitin ligase RNF40: Structure, function and its context‑dependent roles in tumorigenesis (Review)

Zikun Wu, Hang Yang, Guanglong Chen, Weijie Zhao, Banghe Bao, Chai Luv, Wenpu Zhu, Faqiang Liu, Huihan Ai, Zhi Li
Article Number: 121
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 120
Published online on: 27 April 2026

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Article Open Access

Hypermethylation‑induced silencing of ITGA4 promotes oral squamous cell carcinoma progression through SNX5 upregulation

Nguyen Ngoc Thuy Tien, Han-Cheol Choe, Sang-Gun Ahn
Article Number: 119
Published online on: 24 April 2026

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Expression of Concern Open Access

[Expression of Concern] Pifithrin‑μ is efficacious against non‑small cell lung cancer via inhibition of heat shock protein 70

Yang Zhou, Jingping Ma, Jiahong Zhang, Li He, Jianhua Gong, Cong Long
Article Number: 118
Published online on: 22 April 2026

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Article Open Access

Inhibitory role of angiopoietin‑like 4 for cancer progression in oropharyngeal squamous cell carcinoma

Takuya Mikoshiba, Mariko Sekimizu, Nana Nakahara, Shin Saito, Keisuke Yoshihama, Ryoto Nagai, Takeyuki Kono, Hiroyuki Ozawa
Article Number: 117
Published online on: 20 April 2026

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Expression of Concern Open Access

[Expression of Concern] Adenovirus‑mediated truncated Bid overexpression induced by the Cre/LoxP system promotes the cell apoptosis of CD133+ ovarian cancer stem cells

Qifang Long, Ru Yang, Weixian Lu, Weipei Zhu, Jundong Zhou, Cui Zheng, Dongmei Zhou, Ling Yu, Jinchang Wu
Article Number: 116
Published online on: 15 April 2026

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Review Open Access

Incorporating artificial intelligence into morphological diagnosis of acute leukemias: Current landscape, challenges and prospects (Review)

Hui Cheng, Guodong Zheng, Yuanyuan Yang, Chun Xu, Gusheng Tang, Chongmei Huang
Article Number: 115
Published online on: 15 April 2026

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Article Open Access

Mechanistic study of MUC3A in promoting progression of clear cell renal cell carcinoma via the JAK‑STAT pathway

Yongyang Yun, Xing Ji, Shuai Hu, Tianyu Wu, Yixiao Liu, Zheng Li, Zhoujie Sun, Peimin Zhou, Lei Yang, Wei Yu
Article Number: 114
Published online on: 14 April 2026

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Article Open Access

Perturbation of BRD4 and p300 activity suppresses super enhancer‑driven KLF6 expression in renal carcinoma

Nurul Nadia Mohamad Zamberi, Asmaa Y. Abuhamad, Siti Nur Hasanah Mohd Yusuf, Nur Qurratu Athirah A. Rahman, Mohamad Aimanuddin Mohtar, Saiful Effendi Syafruddin
Article Number: 113
Published online on: 14 April 2026

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Article Open Access

PINK1‑mediated mitophagy enhances breast cancer proliferation through metabolic reprogramming

Zong Jin Guo, Qian Yu, Rui Sha, Wei Li, Hui Juan Dai
Article Number: 112
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Metformin inhibits growth and sensitizes osteosarcoma cell lines to cisplatin through cell cycle modulation

Irene Quattrini, Amalia Conti, Laura Pazzaglia, Chiara Novello, Stefano Ferrari, Piero Picci, Maria Serena Benassi
Article Number: 111
Published online on: 08 April 2026

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Article Open Access

NF‑κB‑driven LUZP1 promotes metastasis and chemoresistance in head and neck squamous cell carcinoma

Chen-Yuan Lin, Ching-Yun Hsieh, Hsin-Chi Lan, Ching-Chan Lin, Tzu-Ting Chen, Wei-Chi Tseng, Yung-An Tsou, Wei-Chao Chang
Article Number: 110
Published online on: 07 April 2026

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Article Open Access

Hypoxic CAF studies unveil PTHrP‑vitamin D‑RAS axis as pivotal in the CAF

Shoichiro Nakajo, Mamoru Uemura, Hiroshi Kusafuka, Mao Osaki, Chikako Kusunoki, Nobuo Takiguchi, Mitsunobu Takeda, Yuki Sekido, Tsuyoshi Hata, Atsushi Hamabe, Takayuki Ogino, Norikatsu Miyoshi, Mitsuyoshi Tei, Yoshinori Kagawa, Hirofumi Yamamoto, Yuichiro Doki, Hidetoshi Eguchi
Article Number: 109
Published online on: 07 April 2026

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Retraction Open Access

[Retracted] miR‑24‑3p regulates bladder cancer cell proliferation, migration, invasion and autophagy by targeting DEDD

Guoqiang Yu, Zhaohui Jia, Zhongling Dou
Article Number: 108
Published online on: 06 April 2026

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Review Open Access

Role of CHD4 in tumor progression, DNA damage response and treatment resistance (Review)

Shuo Li, Quan Ma, Keying Lian, Zhisheng Jiang, Yun Ma
Article Number: 107
Published online on: 02 April 2026

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Review Open Access

T cell fate regulation in EBV‑associated nasopharyngeal carcinoma (Review)

Liuyang Zhang, Shun Ding, Dongzhui Chen, Benchi Cai, Zhonglin Mu
Article Number: 106
Published online on: 02 April 2026

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Retraction Open Access

[Retracted] Ultrasound‑targeted microbubble destruction‑mediated overexpression of Sirtuin 3 inhibits the progression of ovarian cancer

Li Cheng, Dongmei Zhang, Wei Yan
Article Number: 105
Published online on: 02 April 2026

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Review Open Access

HMGB3: A pivotal orchestrator of therapy resistance and cancer stemness in human malignancies (Review)

Ju Zhang, Yifan Sun, Lanyu Wang, Jiayu Gu, Ye Hua, Jianfeng Shao, Ninghan Feng
Article Number: 104
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] 5‑Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene

Xiaorong Wang, E. Chen, Xue Yang, Yin Wang, Zhen Quan, Xiaohou Wu, Chunli Luo
Article Number: 103
Published online on: 30 March 2026

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Number: 124
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[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
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