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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2008 Volume 19 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Endometriosis: Pathogenesis, diagnosis, therapy and association with cancer (Review)

Alfonso Baldi, Mara Campioni, Pietro G. Signorile
Pages: 843-846
Published online on: 01 April 2008

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Article

Clinicopathological significance of the fragile histidine triad transcription protein expression in laryngeal carcinogenesis

Koichi Kitamura, Ken Hayashi, Ryo Kobayashi, Hideaki Ishii, Jun Matsubayashi, Tetsuya Matsumoto, Mamoru Suzuki
Pages: 847-852
Published online on: 01 April 2008

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Article

In vivo and in vitro uptake of 111In, delivered with the affibody molecule (ZEGFR:955)2, in EGFR expressing tumour cells

E. Nordberg, A. Orlova, M. Friedman, V. Tolmachev, S. Ståhl, F. Y. Nilsson, B. Glimelius, J. Carlsson
Pages: 853-857
Published online on: 01 April 2008

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Article

Increased expression of calpain 6 during the progression of uterine cervical neoplasia: Immunohistochemical analysis

Sun-Joo Lee, Byoung-Gie Kim, Yoon-La Choi, Jeong-Won Lee
Pages: 859-863
Published online on: 01 April 2008

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Article

BIGH3 is overexpressed in clear cell renal cell carcinoma

Masanori Yamanaka, Fumihiro Kimura, Yutaka Kagata, Nobuo Kondoh, Tomohiko Asano, Mikio Yamamoto, Masamichi Hayakawa
Pages: 865-874
Published online on: 01 April 2008

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Case Report

Two-port hand-assisted laparoscopic surgery for the 2-stage treatment of a complete bowel obstruction by left colon cancer: A case report

Masaya Mukai, Akira Tanaka, Takayuki Tajima, Maki Fukasawa, Takeshi Yamagiwa, Ken-Ichi Okada, Kazuhiko Sato, Kousuke Tobita, Yasuhisa Oida, Hiroyasu Makuuchi
Pages: 875-879
Published online on: 01 April 2008

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Article

Expression of rTSβ as a 5-fluorouracil resistance marker in patients with primary breast cancer

Shou-Jen Kuo, Hwei-Chung Wang, Kuan-Chih Chow, Shiow-Her Chiou, Shu-Fen Chiang, Tze-Yi Lin, I-Ping Chiang, Dar-Ren Chen
Pages: 881-888
Published online on: 01 April 2008

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Article

Generation of multidrug resistant lymphoma cell lines stably expressing P-glycoprotein

Iliodora Pop, Laurentiu Pop, Ellen S. Vitetta, Maria-Ana Ghetie
Pages: 889-895
Published online on: 01 April 2008

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Article

Anti-colon cancer effects of Salograviolide A isolated from Centaurea ainetensis

Nahed El-Najjar, Saadah Dakdouki, Nadine Darwiche, Marwan El-Sabban, Najat A. Saliba, Hala Gali-Muhtasib
Pages: 897-904
Published online on: 01 April 2008

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Article

Leptin and leptin receptor involvement in cancer development: a study on human primary breast carcinoma

Thierry Jardé, Florence Caldefie-Chézet, Mireille Damez, Florence Mishellany, Frédérique Penault-Llorca, Jean Guillot, Marie Paule Vasson
Pages: 905-911
Published online on: 01 April 2008

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Article

Pathological significance of connexin 26 expression in colorectal adenocarcinoma

Ran Hong, Sung-Chul Lim
Pages: 913-919
Published online on: 01 April 2008

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Article

Exploration of the mechanism underlying the tumor necrosis avidity of hypericin

Marie Van de Putte, Yicheng Ni, Peter A.M. De Witte
Pages: 921-926
Published online on: 01 April 2008

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Article

Hypericin as a marker for determination of tissue viability after radiofrequency ablation in a murine liver tumor model

Marie Van de Putte, Huaijun Wang, Feng Chen, Peter A.M. De Witte, Yicheng Ni
Pages: 927-932
Published online on: 01 April 2008

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Article

Myeloid leukemia-1 expression in benign and malignant melanocytic lesions

Ronald P.C. Wong, Shahram Khosravi, Magdalena Martinka, Gang Li
Pages: 933-937
Published online on: 01 April 2008

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Article

Vascular endothelial growth factor receptor-3 is a favorable prognostic factor in advanced gastric carcinoma

Ji-Youn Sung, Sun Lee, Youn Wha Kim, Yong-Koo Park
Pages: 939-944
Published online on: 01 April 2008

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Article

Sequential treatment with SN-38 followed by 5-fluorouracil shows synergistic cytotoxic activity in small cell lung cancer cells

Kenichi Takeda, Hisashi Suyama, Tadashi Igishi, Yasushi Shigeoka, Shingo Matsumoto, Akira Yamasaki, Kiyoshi Hashimoto, Takashi Sumikawa, Masato Morita, Yasuto Ueda, Eiji Shimizu
Pages: 945-951
Published online on: 01 April 2008

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Article

Reduced expression of the claudin-7 gene correlates with venous invasion and liver metastasis in colorectal cancer

Takashi Oshima, Chikara Kunisaki, Kazue Yoshihara, Roppei Yamada, Naoto Yamamoto, Tsutomu Sato, Hirochika Makino, Shigeru Yamagishi, Yasuhiko Nagano, Shoich Fujii, Manabu Shiozawa, Makoto Akaike, Nobuyuki Wada, Yasushi Rino, Munetaka Masuda, Katsuaki Tanaka, Toshio Imada
Pages: 953-959
Published online on: 01 April 2008

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Article

Induction of apoptosis by piceatannol in human leukemic U937 cells through down-regulation of Bcl-2 and activation of caspases

Yeong Hoon Kim, Cheol Park, Jeong Ok Lee, Gi Young Kim, Won Ho Lee, Yung Hyun Choi, Chung Ho Ryu
Pages: 961-967
Published online on: 01 April 2008

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Article

A possible role of BDNF in prostate cancer detection

E. Bronzetti, M. Artico, F. Forte, G. Pagliarella, L. M. Felici, A. D'Ambrosio, G. Vespasiani, B. Bronzetti
Pages: 969-974
Published online on: 01 April 2008

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Article

The cysteine-cluster motif of c-Yes, Lyn and FAK as a suppressive module for the kinases

Mohammad Aminur Rahman, Takeshi Senga, Myat Lin Oo, Hitoki Hasegawa, Md. Helal Uddin Biswas, Naing Naing Mon, Pengyu Huang, Satoko Ito, Tadashi Yamamoto, Michinari Hamaguchi
Pages: 975-980
Published online on: 01 April 2008

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Article

Clinical characteristics of small cell carcinoma of the breast

Noriaki Sadanaga, Satoko Okada, Satoko Shiotani, Masaru Morita, Yoshihiro Kakeji, Kaoru Kitamura, Sadafumi Tamiya, Keizo Sugimachi, Yoshihiko Maehara
Pages: 981-985
Published online on: 01 April 2008

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Article

The induction of insulinomas by X-irradiation to the gastric region in Otsuka Long-Evans Tokushima Fatty rats

Hiromitsu Watanabe, Kenji Kamiya
Pages: 987-991
Published online on: 01 April 2008

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Article

Up-regulation of stromal cell-derived factor-1α and its receptor CXCR4 expression accompanied with epithelial-mesenchymal transition in human oral squamous cell carcinoma

Masayuki Taki, Koichiro Higashikawa, Shingo Yoneda, Shigehiro Ono, Hideo Shigeishi, Masaru Nagayama, Nobuyuki Kamata
Pages: 993-998
Published online on: 01 April 2008

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Article

ATR alterations in Hodgkin's lymphoma

Angen Liu, Tetsuya Takakuwa, Shigeki Fujita, Wen-Juan Luo, Kristianti Tresnasari, Anke Van den Berg, Sibrand Poppema, Katsuyuki Aozasa
Pages: 999-1005
Published online on: 01 April 2008

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Article

Activation of matrix metalloproteinase-9 by TNF-α in human urinary bladder cancer HT1376 cells: The role of MAP kinase signaling pathways

Se-Jung Lee, Sung-Soo Park, Young-Hwa Cho, Keerang Park, Eun-Jung Kim, Kyung-Hwan Jung, Si-Kwan Kim, Wun-Jae Kim, Sung-Kwon Moon
Pages: 1007-1013
Published online on: 01 April 2008

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Article

EVL (Ena/VASP-like) expression is up-regulated in human breast cancer and its relative expression level is correlated with clinical stages

Li-De Hu, Hua-Fei Zou, Shu-Xuan Zhan, Kai-Ming Cao
Pages: 1015-1020
Published online on: 01 April 2008

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Article

Platelet production and related pathophysiology in acute myelogenous leukemia at first diagnosis: Prognostic implications

Dimitrios T.P. Trafalis, Elias Poulakidas, Violeta Kapsimali, Christos Tsigris, Xenofon Papanicolaou, Nikolaos Harhalakis, Emmanuel Nikiforakis, Chrisanthi Mentzikof-Mitsouli
Pages: 1021-1026
Published online on: 01 April 2008

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Article

Effects of the proteasome inhibitor bortezomib alone and in combination with chemotherapeutic agents in gastric cancer cell lines

Sung Hwa Bae, Hun-Mo Ryoo, Min Kyoung Kim, Kyung Hee Lee, Jeong-Im Sin, Myung Soo Hyun
Pages: 1027-1032
Published online on: 01 April 2008

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Article

Prevalence of BER gene polymorphisms in sporadic breast cancer

Mohamed F. Ali, Jane L. Meza, Eleanor G. Rogan, Dhrubajyoti Chakravarti
Pages: 1033-1038
Published online on: 01 April 2008

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Article

The integrin antagonist cilengitide increases the antitumor activity of temozolomide against malignant melanoma

Lucio Tentori, Annalisa Susanna Dorio, Alessia Muzi, Pedro Miguel Lacal, Federica Ruffini, Pierluigi Navarra, Grazia Graziani
Pages: 1039-1043
Published online on: 01 April 2008

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Article

Aberrant expression of the glycolytic enzymes aldolase B and type II hexokinase in hepatocellular carcinoma are predictive markers for advanced stage, early recurrence and poor prognosis

Shian-Yang Peng, Po-Lin Lai, Hung-Wei Pan, Li-Pin Hsiao, Hey-Chi Hsu
Pages: 1045-1053
Published online on: 01 April 2008

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Article

Detection of isolated tumour cells in the blood and bone marrow of patients with gastric cancer by combined sorting, isolation and determination of MAGE-1, -2 mRNA expression

Rafal Szatanek, Grazyna Drabik, Jaroslaw Baran, Piotr Kolodziejczyk, Jan Kulig, Jerzy Stachura, Marek Zembala
Pages: 1055-1060
Published online on: 01 April 2008

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Article

The topoisomerase II inhibitor, genistein, induces G2/M arrest and apoptosis in human malignant glioma cell lines

Friederike Schmidt, Christiane B. Knobbe, Brigitte Frank, Hartwig Wolburg, Michael Weller
Pages: 1061-1066
Published online on: 01 April 2008

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Impact of the intratumoral resident microbiome on the immune microenvironment of malignant tumors (Review)

Han Na Oh, Hoon Hur
Article Number: 66
Published online on: 06 February 2026

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Correction Open Access

[Corrigendum] Hypoxia and macrophages promote glioblastoma invasion by the CCL4‑CCR5 axis

Ying Wang, Tao Liu, Ning Yang, Shuo Xu, Xingang Li, Donghai Wang
Article Number: 65
Published online on: 04 February 2026

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Review Open Access

Origin dictates function: The dual roles of exosomes derived from diverse origins in the onset and progression of colorectal cancer (Review)

Zhao Guo, Haoyan Zhuang, Qingfeng Liu
Article Number: 64
Published online on: 03 February 2026

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Article Open Access

Quercetin reduces expression of ATP‑binding cassette transporters by regulating the PTEN/PI3K/AKT signaling pathway in breast cancer cells

Wentao Fu, Leying Lin, Jie Li, Fei Qin, Chuan Chen, Yinglian Cai, Yilun Cai, Yiling Huang, Wang Yang, Shanshan Zhu
Article Number: 63
Published online on: 02 February 2026

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Article Open Access

POSTN+ fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling

Chenyang Zhang, Si Chen, Chenghui Qian, Wanqi Lv, Qian Zhang, Yanjin Wang, Yuqiong Wu, Xue Liu
Article Number: 62
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] EGFR/HER2 inhibitors effectively reduce the malignant potential of MDR breast cancer evoked by P‑gp substrates in vitro and in vivo

Yiting Jin, Wei Zhang, Hongying Wang, Zijing Zhang, Chengyu Chu, Xiuping Liu, Qiang Zou
Article Number: 61
Published online on: 02 February 2026

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Article

Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Review Open Access

Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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Article Open Access

TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Review Open Access

Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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Article Open Access

High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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