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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2011 Volume 25 Issue 1

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

EGFR, HER2 and HER3 expression in primary colorectal carcinomas and corresponding metastases: Implications for targeted radionuclide therapy

Q. Wei, Y. Shui, S. Zheng, K. Wester, H. Nordgren, P. Nygren, B. Glimelius, J. Carlsson
Pages: 3-11
Published online on: 01 January 2011

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Article Open Access

The proliferation marker Chromatin Assembly Factor-1 is of clinical value in predicting the biological behaviour of salivary gland tumours

Stefania Staibano, Massimo Mascolo, Alba Rocco, Lorenzo Lo Muzio, Gennaro Ilardi, Maria Siano, Giuseppe Pannone, Maria Luisa Vecchione, Loredana Nugnes, Luigi Califano, Rosanna Zamparese, Pantaleo Bufo, Gaetano De Rosa
Pages: 13-22
Published online on: 01 January 2011

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Article

Thymosin β4 expression correlates with lymph node metastasis through hypoxia inducible factor-α induction in breast cancer

Sun Young Yoon, Ha Reum Lee, Yoorim Park, Joo Heon Kim, Soo Young Kim, Suk Ran Yoon, Wang Jae Lee, Byung Joo Cho, Hyeyoung Min, Jung-Wook Bang, Hyunjeong Park, Sa Ik Bang, Daeho Cho
Pages: 23-31
Published online on: 01 January 2011

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Article

Synergistic therapeutic effects of cytokine-induced killer cells and temozolomide against glioblastoma

Juyoun Jin, Kyeung Min Joo, Se Jeong Lee, Mi-Young Jo, Yonghyun Kim, Younggeon Jin, Joong Kyu Kim, Ji Mi Ahn, Mi-Jung Yoon, Jaeseung Lim, Do-Hyun Nam
Pages: 33-39
Published online on: 01 January 2011

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Article

Statin-mediated reduction of osteopontin expression induces apoptosis and cell growth arrest in ovarian clear cell carcinoma

Motoki Matsuura, Takahiro Suzuki, Miwa Suzuki, Ryoichi Tanaka, Eiki Ito, Tsuyoshi Saito
Pages: 41-47
Published online on: 01 January 2011

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Article

The expression profile of apoptosis-related genes in the chicken as a human epithelial ovarian cancer model

Hee Won Seo, Deivendran Rengaraj, Jin Won Choi, Kyung Je Park, Gwonhwa Song, Jae Yong Han
Pages: 49-56
Published online on: 01 January 2011

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Article

Characteristics of severe adverse events after peptide vaccination for advanced cancer patients: Analysis of 500 cases

Kazumi Yoshida, Masanori Noguchi, Takashi Mine, Nobukazu Komatsu, Shigeru Yutani, Takato Ueno, Hiroaki Yanagimoto, Kouichirou Kawano, Kyogo Itoh, Akira Yamada
Pages: 57-62
Published online on: 01 January 2011

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Article

Combined treatment of tumor-tropic human neural stem cells containing the CD suicide gene effectively targets brain tumors provoking a mild immune response

Se Jeong Lee, Yonghyun Kim, Mi-Young Jo, Hyeong-Seok Kim, Younggeon Jin, Seung U. Kim, Juyoun Jin, Kyeung Min Joo, Do-Hyun Nam
Pages: 63-68
Published online on: 01 January 2011

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Article

Occult neoplastic cells in the lymph node sinuses and recurrence/metastasis of stage II/Dukes' B colorectal cancer

Yasutomo Sekido, Masaya Mukai, Kyoko Kishima, Takayuki Tajima, Tatsuhiko Hoshikawa, Masato Nakamura, Naoya Nakamura, Kyoji Ogoshi
Pages: 69-73
Published online on: 01 January 2011

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Article

Overexpression of the hBiot2 gene is associated with development of human cervical cancer

Yang-Mei Shen, Xiang He, Hong-Xin Deng, Yu-Ping Xie, Chun-Ting Wang, Yu-Quan Wei, Xia Zhao
Pages: 75-80
Published online on: 01 January 2011

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Article

Troglitazone attenuates epidermal growth factor receptor signaling independently of peroxisome proliferator-activated receptor in PC-3 cells

Hai Zhu, Xiaojing Pan, Haiyan Qi, Xuechun Wang, Sichuan Hou, Baojian Han, Zhijun Liu, Luo Xu
Pages: 81-90
Published online on: 01 January 2011

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Article

Color flow mapping: a non-invasive tool for characterizing and differentiating between uveal melanomas and choroidal metastases

Meira Neudorfer, Michael Waisbourd, Irene Anteby, Alon Liran, Dafna Goldenberg, Adiel Barak, Ada Kessler
Pages: 91-96
Published online on: 01 January 2011

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Article

Adenovirus-mediated shRNAs for co-repression of miR-221 and miR-222 expression and function in glioblastoma cells

Xuan Wang, Lei Han, Anling Zhang, Guangxiu Wang, Zhifan Jia, Yang Yang, Xiao Yue, Peiyu Pu, Changhong Shen, Chunsheng Kang
Pages: 97-105
Published online on: 01 January 2011

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Article

Differential methylation of CpG islands within the dermo1 gene promoter in several cancer cell lines

Yubin Mao, Hween-Boon Toh, Zhijie Ding, Lifang Sun, Liang Hong, Chien-Shing Chen, Xueji Wu
Pages: 107-111
Published online on: 01 January 2011

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Case Report

Clinical, radiological and biological features of lung metastases in gastrointestinal stromal tumors (Case reports)

Margherita Nannini, Guido Biasco, Valerio Di Scioscio, Monica Di Battista, Maurizio Zompatori, Fausto Catena, Paolo Castellucci, Paola Paterini, Angelo Paolo Dei Tos, Franco Stella, Alessandra Maleddu, Maria Abbondanza Pantaleo
Pages: 113-120
Published online on: 01 January 2011

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Article

Novel human prostate cell lines derived from the transition and peripheral zones of the prostate for carcinogenesis studies

Jennifer Weaver, Cecilie Briscoe, Slawomir Kata, Chris Goodman, Horst Zitzelsberger, Ludwig Hieber, Andrew Riches
Pages: 121-128
Published online on: 01 January 2011

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Article

Anillin expression is a marker of favourable prognosis in patients with renal cell carcinoma

Hanna Ronkainen, Pasi Hirvikoski, Saila Kauppila, Markku H. Vaarala
Pages: 129-133
Published online on: 01 January 2011

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Article

The anti-diabetic drug metformin suppresses the metastasis-associated protein CD24 in MDA-MB-468 triple-negative breast cancer cells

Alejandro Vazquez-Martin, Cristina Oliveras-Ferraros, Silvia Cufí, Sonia Del Barco, Begoña Martin-Castillo, Eugeni Lopez-Bonet, Javier A. Menendez
Pages: 135-140
Published online on: 01 January 2011

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Article

Description of the CD133+ subpopulation of the human ovarian cancer cell line OVCAR3

Rongjiao Guo, Qiuhua Wu, Fenghua Liu, Yifeng Wang
Pages: 141-146
Published online on: 01 January 2011

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Article

Immunolabelling of the inhibin/activin-βC subunit in normal and malignant human uterine cervical tissue and cervical cancer cell lines

Thomas Blankenstein, Julia Jückstock, Naim Shabani, Susanne Kunze, Ansgar Brüning, Florian Bergauer, Ioannis Mylonas
Pages: 147-152
Published online on: 01 January 2011

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Article

Ectopic expression of activation-induced cytidine deaminase caused by epigenetics modification

Masayuki Tatemichi, Harumi Hata, Toshio Nakadate
Pages: 153-158
Published online on: 01 January 2011

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Article

Vitamin K2 augments 5-fluorouracil-induced growth inhibition of human hepatocellular carcinoma cells by inhibiting NF-κB activation

Hao Zhang, Iwata Ozaki, Hiroshi Hamajima, Shinji Iwane, Hirokazu Takahashi, Yasunori Kawaguchi, Yuichiro Eguchi, Kyosuke Yamamoto, Toshihiko Mizuta
Pages: 159-166
Published online on: 01 January 2011

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Article Open Access

Polymorphisms in genes involved in folate metabolism and plasma DNA methylation in colorectal cancer patients

Jong Woo Kim, Hye Mi Park, Young-Kook Choi, So Young Chong, Doyeun Oh, Nam Keun Kim
Pages: 167-172
Published online on: 01 January 2011

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Article

Epigenetic modification of RhoE expression in gastric cancer cells

Ji Chen, Haijun Zhou, Qiu Li, Meng Qiu, Zhiping Li, Qiulin Tang, Ming Liu, Yajie Zhu, Juan Huang, Nan Lang, Zhen Liu, Yu Deng, Siyuan Zhang, Feng Bi
Pages: 173-180
Published online on: 01 January 2011

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Article

A novel approach to rescue immune escape in oral squamous cell carcinoma: Combined use of interferon-γ and LY294002

Wei Han, Hongya Pan, Linlin Jiang, Kuijie Wei, Duohong Zou, Zhiyuan Zhang
Pages: 181-187
Published online on: 01 January 2011

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Article

Cancer cachexia: Physical activity and muscle force in tumour-bearing rats

Míriam Toledo, Sílvia Busquets, Sònia Sirisi, Roberto Serpe, Marcel Orpí, Joana Coutinho, Raquel Martínez, Francisco J. López-Soriano, Josep M. Argilés
Pages: 189-193
Published online on: 01 January 2011

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Article

mda-7/IL-24 induces apoptosis in human GBC-SD gallbladder carcinoma cells via mitochondrial apoptotic pathway

Jianguang Jia, Songgang Li, Wei Gong, Jing Ding, Cuifu Fang, Zhiwei Quan
Pages: 195-201
Published online on: 01 January 2011

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Article

IGF-II promoter specific methylation and expression in epithelial ovarian cancer and their associations with disease characteristics

Biyun Qian, Dionyssios Katsaros, Lingeng Lu, Emilie Marion Canuto, Chiara Benedetto, Alicia Beeghly-Fadiel, Herbert Yu
Pages: 203-213
Published online on: 01 January 2011

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Article

Terpenic subfraction of Pterodon pubescens induces apoptosis of K562 leukemic cells by modulating gene expression

Monica Farah Pereira, Thiago Martino, Sergio Ranto Dalmau, Rodolfo Mattos Albano, Jean-Pierre Férézou, Sonia Soares Costa, Marsen Garcia Pinto Coelho, Kátia Gosta Carvalho Sabino
Pages: 215-221
Published online on: 01 January 2011

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Article

Esculetin inhibits cell proliferation through the Ras/ERK1/2 pathway in human colon cancer cells

Sung-Suk Park, Sung-Kyu Park, Jung-Hyurk Lim, Yung Hyun Choi, Wun-Jae Kim, Sung-Kwon Moon
Pages: 223-230
Published online on: 01 January 2011

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Article

Finding a novel interacting protein of the hepatic carcinoma related gene MIP: NF-κB essential modulator (NEMO)

Xiaoxia Ye, Hong Lu, Keke Huo, Dong Chen
Pages: 231-235
Published online on: 01 January 2011

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Article

Overexpression of sorcin results in multidrug resistance in gastric cancer cells with up-regulation of P-gp

Qingchun He, Guiying Zhang, Defu Hou, Aiming Leng, Meihua Xu, Jie Peng, Ting Liu
Pages: 237-243
Published online on: 01 January 2011

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Article

The role of ADCYAP1, adenylate cyclase activating polypeptide 1, as a methylation biomarker for the early detection of cervical cancer

Samil Jung, Lisha Yi, Dongjun Jeong, Jinsun Kim, Sungwhan An, Tae-Jeong Oh, Chang-Hwan Kim, Chang-Jin Kim, Young Yang, Keun Il Kim, Jong-Seok Lim, Myeong-Sok Lee
Pages: 245-252
Published online on: 01 January 2011

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Article

Tissue sampling for mutation analysis in colorectal cancer: K-ras is homogeneously distributed throughout the tumor tissue

Susanne Ekelund, Nikos Papadogiannakis, Hans Olivecrona, Ulrik Lindforss
Pages: 253-258
Published online on: 01 January 2011

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Article

Effects of shRNA targeting maspin on invasion of gastric carcinoma SGC7901 cell line

Yaying Yang, Haipeng Shi, Xiujun Li, Yongfen Yi
Pages: 259-265
Published online on: 01 January 2011

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Article

A novel polysaccharide from Se-enriched Ganoderma lucidum induces apoptosis of human breast cancer cells

Dejing Shang, Yang Li, Che Wang, Xiaomin Wang, Zhi Yu, Xin Fu
Pages: 267-272
Published online on: 01 January 2011

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Article

Involvement of let-7/miR-98 microRNAs in the regulation of progesterone receptor membrane component 1 expression in ovarian cancer cells

Alexandra Wendler, Daniela Keller, Christian Albrecht, John J. Peluso, Martin Wehling
Pages: 273-279
Published online on: 01 January 2011

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Article

NK1.1+ cells are important for the development of protective immunity against MHC I-deficient, HPV16-associated tumours

Marie Indrová, Jana Símová, Jana Bieblová, Jan Bubeník, Milan Reinis
Pages: 281-288
Published online on: 01 January 2011

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Article

Side population in MDA-MB-231 human breast cancer cells exhibits cancer stem cell-like properties without higher bone-metastatic potential

Toru Hiraga, Susumu Ito, Hiroaki Nakamura
Pages: 289-296
Published online on: 01 January 2011

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Genomic instability, postoperative recurrence and therapeutic vulnerabilities in resectable non‑small cell lung cancer (Review)

Linlin Wang, Yong Feng, Qiang Liu
Article Number: 182
Published online on: 28 August 2026

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Review Open Access

Research progress on lactate metabolism in lung cancer: Tumorigenesis, drug resistance and clinical translation (Review)

Yuantao Zhang, Yiyang Shang, Hai Zeng, Ruiling Ning, Xinran Zhang, Dongxu Ao, Jun Cai, Qingqing Ye
Article Number: 181
Published online on: 28 August 2026

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Review Open Access

Decoding the metabolic‑immune crosstalk: The role of glutamine and ammonium reprogramming in prostate cancer immune evasion (Review)

Peilong Wang, Xiaoran Li, Teng Ma, Jun Mi
Article Number: 180
Published online on: 27 August 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells

Jing Guo, Li Chen, Ning Luo, Weihong Yang, Xiaoyan Qu, Zhongping Cheng
Article Number: 179
Published online on: 24 August 2026

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Article Open Access

Combination of lonidamine with devimistat induces synergistic antitumor effects in lung cancer via multifaceted disruption of cellular energy metabolism

Xinhe Bai, Yongfeng Yang, Yuling Luo, Pei Jing, Xia Hong, Yaqin Zou, Yan Dai, Xuping Yang, Meiling Zhou, Han Xiao, Yilan Huang, Shiwei Guo, Qingze Fan
Article Number: 178
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Targeting ribonucleotide reductase M2 subunit by small interfering RNA exerts anti‑oncogenic effects in gastric adenocarcinoma 

Wei Kang, Joanna H.M. Tong, Anthony W.H. Chan, Junhong Zhao, Shiyan Wang, Yujuan Dong, Frankie M.C. Sin, Saifung Yeung, Alfred S.L. Cheng, Jun Yu, Kafai To
Article Number: 177
Published online on: 20 August 2026

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Article Open Access

Cancer‑associated fibroblast‑derived extracellular vesicles promote pancreatic cancer progression via the RAP1B/ANLN axis

Daigo Yoshimori, Mitsuhiro Kudo, Kousuke Ishino, Junji Ueda, Yukako Shintani-Domoto, Akira Matsushita, Youichi Kawano, Takashi Ono, Takahiro Haruna, Kazuhiko Endo, Akira Hamaguchi, Takenori Fujii, Yoko Kawamoto, Kiyoshi Teduka, Taeko Kitamura, Atsushi Masamune, Akihisa Matsuda, Hiroshi Yoshida, Ryuji Ohashi
Article Number: 176
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Restoration of the tumor‑suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells

Dan Jiang, Lingyao Wang, Tong Zhao, Zhaoyu Zhang, Renxia Zhang, Jingji Jin, Yong Cai, Fei Wang
Article Number: 175
Published online on: 17 August 2026

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Review Open Access

Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review)

Shujing Xia, Xiumei Zhang, Lizhong Tang, Anqi Li, Jianhai Chen, Zhang Tao
Article Number: 174
Published online on: 14 August 2026

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Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Correction Open Access

[Corrigendum] TGF‑β1 mediates epithelial to mesenchymal transition via the TGF‑β/Smad pathway in squamous cell carcinoma of the head and neck

Changyun Yu, Yong Liu, Donghai Huang, Yaozhang Dai, Gengming Cai, Jinjie Sun, Ting Xu, Yongquan Tian, Xin Zhang
Article Number: 183
Published online on: 31 August 2026

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