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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2011 Volume 25 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

EGFR, HER2 and HER3 expression in primary colorectal carcinomas and corresponding metastases: Implications for targeted radionuclide therapy

Q. Wei, Y. Shui, S. Zheng, K. Wester, H. Nordgren, P. Nygren, B. Glimelius, J. Carlsson
Pages: 3-11
Published online on: 01 January 2011

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Article Open Access

The proliferation marker Chromatin Assembly Factor-1 is of clinical value in predicting the biological behaviour of salivary gland tumours

Stefania Staibano, Massimo Mascolo, Alba Rocco, Lorenzo Lo Muzio, Gennaro Ilardi, Maria Siano, Giuseppe Pannone, Maria Luisa Vecchione, Loredana Nugnes, Luigi Califano, Rosanna Zamparese, Pantaleo Bufo, Gaetano De Rosa
Pages: 13-22
Published online on: 01 January 2011

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Article

Thymosin β4 expression correlates with lymph node metastasis through hypoxia inducible factor-α induction in breast cancer

Sun Young Yoon, Ha Reum Lee, Yoorim Park, Joo Heon Kim, Soo Young Kim, Suk Ran Yoon, Wang Jae Lee, Byung Joo Cho, Hyeyoung Min, Jung-Wook Bang, Hyunjeong Park, Sa Ik Bang, Daeho Cho
Pages: 23-31
Published online on: 01 January 2011

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Article

Synergistic therapeutic effects of cytokine-induced killer cells and temozolomide against glioblastoma

Juyoun Jin, Kyeung Min Joo, Se Jeong Lee, Mi-Young Jo, Yonghyun Kim, Younggeon Jin, Joong Kyu Kim, Ji Mi Ahn, Mi-Jung Yoon, Jaeseung Lim, Do-Hyun Nam
Pages: 33-39
Published online on: 01 January 2011

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Article

Statin-mediated reduction of osteopontin expression induces apoptosis and cell growth arrest in ovarian clear cell carcinoma

Motoki Matsuura, Takahiro Suzuki, Miwa Suzuki, Ryoichi Tanaka, Eiki Ito, Tsuyoshi Saito
Pages: 41-47
Published online on: 01 January 2011

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Article

The expression profile of apoptosis-related genes in the chicken as a human epithelial ovarian cancer model

Hee Won Seo, Deivendran Rengaraj, Jin Won Choi, Kyung Je Park, Gwonhwa Song, Jae Yong Han
Pages: 49-56
Published online on: 01 January 2011

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Article

Characteristics of severe adverse events after peptide vaccination for advanced cancer patients: Analysis of 500 cases

Kazumi Yoshida, Masanori Noguchi, Takashi Mine, Nobukazu Komatsu, Shigeru Yutani, Takato Ueno, Hiroaki Yanagimoto, Kouichirou Kawano, Kyogo Itoh, Akira Yamada
Pages: 57-62
Published online on: 01 January 2011

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Article

Combined treatment of tumor-tropic human neural stem cells containing the CD suicide gene effectively targets brain tumors provoking a mild immune response

Se Jeong Lee, Yonghyun Kim, Mi-Young Jo, Hyeong-Seok Kim, Younggeon Jin, Seung U. Kim, Juyoun Jin, Kyeung Min Joo, Do-Hyun Nam
Pages: 63-68
Published online on: 01 January 2011

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Article

Occult neoplastic cells in the lymph node sinuses and recurrence/metastasis of stage II/Dukes' B colorectal cancer

Yasutomo Sekido, Masaya Mukai, Kyoko Kishima, Takayuki Tajima, Tatsuhiko Hoshikawa, Masato Nakamura, Naoya Nakamura, Kyoji Ogoshi
Pages: 69-73
Published online on: 01 January 2011

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Article

Overexpression of the hBiot2 gene is associated with development of human cervical cancer

Yang-Mei Shen, Xiang He, Hong-Xin Deng, Yu-Ping Xie, Chun-Ting Wang, Yu-Quan Wei, Xia Zhao
Pages: 75-80
Published online on: 01 January 2011

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Article

Troglitazone attenuates epidermal growth factor receptor signaling independently of peroxisome proliferator-activated receptor in PC-3 cells

Hai Zhu, Xiaojing Pan, Haiyan Qi, Xuechun Wang, Sichuan Hou, Baojian Han, Zhijun Liu, Luo Xu
Pages: 81-90
Published online on: 01 January 2011

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Article

Color flow mapping: a non-invasive tool for characterizing and differentiating between uveal melanomas and choroidal metastases

Meira Neudorfer, Michael Waisbourd, Irene Anteby, Alon Liran, Dafna Goldenberg, Adiel Barak, Ada Kessler
Pages: 91-96
Published online on: 01 January 2011

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Article

Adenovirus-mediated shRNAs for co-repression of miR-221 and miR-222 expression and function in glioblastoma cells

Xuan Wang, Lei Han, Anling Zhang, Guangxiu Wang, Zhifan Jia, Yang Yang, Xiao Yue, Peiyu Pu, Changhong Shen, Chunsheng Kang
Pages: 97-105
Published online on: 01 January 2011

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Article

Differential methylation of CpG islands within the dermo1 gene promoter in several cancer cell lines

Yubin Mao, Hween-Boon Toh, Zhijie Ding, Lifang Sun, Liang Hong, Chien-Shing Chen, Xueji Wu
Pages: 107-111
Published online on: 01 January 2011

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Case Report

Clinical, radiological and biological features of lung metastases in gastrointestinal stromal tumors (Case reports)

Margherita Nannini, Guido Biasco, Valerio Di Scioscio, Monica Di Battista, Maurizio Zompatori, Fausto Catena, Paolo Castellucci, Paola Paterini, Angelo Paolo Dei Tos, Franco Stella, Alessandra Maleddu, Maria Abbondanza Pantaleo
Pages: 113-120
Published online on: 01 January 2011

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Article

Novel human prostate cell lines derived from the transition and peripheral zones of the prostate for carcinogenesis studies

Jennifer Weaver, Cecilie Briscoe, Slawomir Kata, Chris Goodman, Horst Zitzelsberger, Ludwig Hieber, Andrew Riches
Pages: 121-128
Published online on: 01 January 2011

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Article

Anillin expression is a marker of favourable prognosis in patients with renal cell carcinoma

Hanna Ronkainen, Pasi Hirvikoski, Saila Kauppila, Markku H. Vaarala
Pages: 129-133
Published online on: 01 January 2011

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Article

The anti-diabetic drug metformin suppresses the metastasis-associated protein CD24 in MDA-MB-468 triple-negative breast cancer cells

Alejandro Vazquez-Martin, Cristina Oliveras-Ferraros, Silvia Cufí, Sonia Del Barco, Begoña Martin-Castillo, Eugeni Lopez-Bonet, Javier A. Menendez
Pages: 135-140
Published online on: 01 January 2011

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Article

Description of the CD133+ subpopulation of the human ovarian cancer cell line OVCAR3

Rongjiao Guo, Qiuhua Wu, Fenghua Liu, Yifeng Wang
Pages: 141-146
Published online on: 01 January 2011

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Article

Immunolabelling of the inhibin/activin-βC subunit in normal and malignant human uterine cervical tissue and cervical cancer cell lines

Thomas Blankenstein, Julia Jückstock, Naim Shabani, Susanne Kunze, Ansgar Brüning, Florian Bergauer, Ioannis Mylonas
Pages: 147-152
Published online on: 01 January 2011

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Article

Ectopic expression of activation-induced cytidine deaminase caused by epigenetics modification

Masayuki Tatemichi, Harumi Hata, Toshio Nakadate
Pages: 153-158
Published online on: 01 January 2011

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Article

Vitamin K2 augments 5-fluorouracil-induced growth inhibition of human hepatocellular carcinoma cells by inhibiting NF-κB activation

Hao Zhang, Iwata Ozaki, Hiroshi Hamajima, Shinji Iwane, Hirokazu Takahashi, Yasunori Kawaguchi, Yuichiro Eguchi, Kyosuke Yamamoto, Toshihiko Mizuta
Pages: 159-166
Published online on: 01 January 2011

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Article Open Access

Polymorphisms in genes involved in folate metabolism and plasma DNA methylation in colorectal cancer patients

Jong Woo Kim, Hye Mi Park, Young-Kook Choi, So Young Chong, Doyeun Oh, Nam Keun Kim
Pages: 167-172
Published online on: 01 January 2011

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Article

Epigenetic modification of RhoE expression in gastric cancer cells

Ji Chen, Haijun Zhou, Qiu Li, Meng Qiu, Zhiping Li, Qiulin Tang, Ming Liu, Yajie Zhu, Juan Huang, Nan Lang, Zhen Liu, Yu Deng, Siyuan Zhang, Feng Bi
Pages: 173-180
Published online on: 01 January 2011

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Article

A novel approach to rescue immune escape in oral squamous cell carcinoma: Combined use of interferon-γ and LY294002

Wei Han, Hongya Pan, Linlin Jiang, Kuijie Wei, Duohong Zou, Zhiyuan Zhang
Pages: 181-187
Published online on: 01 January 2011

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Article

Cancer cachexia: Physical activity and muscle force in tumour-bearing rats

Míriam Toledo, Sílvia Busquets, Sònia Sirisi, Roberto Serpe, Marcel Orpí, Joana Coutinho, Raquel Martínez, Francisco J. López-Soriano, Josep M. Argilés
Pages: 189-193
Published online on: 01 January 2011

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Article

mda-7/IL-24 induces apoptosis in human GBC-SD gallbladder carcinoma cells via mitochondrial apoptotic pathway

Jianguang Jia, Songgang Li, Wei Gong, Jing Ding, Cuifu Fang, Zhiwei Quan
Pages: 195-201
Published online on: 01 January 2011

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Article

IGF-II promoter specific methylation and expression in epithelial ovarian cancer and their associations with disease characteristics

Biyun Qian, Dionyssios Katsaros, Lingeng Lu, Emilie Marion Canuto, Chiara Benedetto, Alicia Beeghly-Fadiel, Herbert Yu
Pages: 203-213
Published online on: 01 January 2011

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Article

Terpenic subfraction of Pterodon pubescens induces apoptosis of K562 leukemic cells by modulating gene expression

Monica Farah Pereira, Thiago Martino, Sergio Ranto Dalmau, Rodolfo Mattos Albano, Jean-Pierre Férézou, Sonia Soares Costa, Marsen Garcia Pinto Coelho, Kátia Gosta Carvalho Sabino
Pages: 215-221
Published online on: 01 January 2011

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Article

Esculetin inhibits cell proliferation through the Ras/ERK1/2 pathway in human colon cancer cells

Sung-Suk Park, Sung-Kyu Park, Jung-Hyurk Lim, Yung Hyun Choi, Wun-Jae Kim, Sung-Kwon Moon
Pages: 223-230
Published online on: 01 January 2011

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Article

Finding a novel interacting protein of the hepatic carcinoma related gene MIP: NF-κB essential modulator (NEMO)

Xiaoxia Ye, Hong Lu, Keke Huo, Dong Chen
Pages: 231-235
Published online on: 01 January 2011

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Article

Overexpression of sorcin results in multidrug resistance in gastric cancer cells with up-regulation of P-gp

Qingchun He, Guiying Zhang, Defu Hou, Aiming Leng, Meihua Xu, Jie Peng, Ting Liu
Pages: 237-243
Published online on: 01 January 2011

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Article

The role of ADCYAP1, adenylate cyclase activating polypeptide 1, as a methylation biomarker for the early detection of cervical cancer

Samil Jung, Lisha Yi, Dongjun Jeong, Jinsun Kim, Sungwhan An, Tae-Jeong Oh, Chang-Hwan Kim, Chang-Jin Kim, Young Yang, Keun Il Kim, Jong-Seok Lim, Myeong-Sok Lee
Pages: 245-252
Published online on: 01 January 2011

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Article

Tissue sampling for mutation analysis in colorectal cancer: K-ras is homogeneously distributed throughout the tumor tissue

Susanne Ekelund, Nikos Papadogiannakis, Hans Olivecrona, Ulrik Lindforss
Pages: 253-258
Published online on: 01 January 2011

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Article

Effects of shRNA targeting maspin on invasion of gastric carcinoma SGC7901 cell line

Yaying Yang, Haipeng Shi, Xiujun Li, Yongfen Yi
Pages: 259-265
Published online on: 01 January 2011

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Article

A novel polysaccharide from Se-enriched Ganoderma lucidum induces apoptosis of human breast cancer cells

Dejing Shang, Yang Li, Che Wang, Xiaomin Wang, Zhi Yu, Xin Fu
Pages: 267-272
Published online on: 01 January 2011

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Article

Involvement of let-7/miR-98 microRNAs in the regulation of progesterone receptor membrane component 1 expression in ovarian cancer cells

Alexandra Wendler, Daniela Keller, Christian Albrecht, John J. Peluso, Martin Wehling
Pages: 273-279
Published online on: 01 January 2011

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Article

NK1.1+ cells are important for the development of protective immunity against MHC I-deficient, HPV16-associated tumours

Marie Indrová, Jana Símová, Jana Bieblová, Jan Bubeník, Milan Reinis
Pages: 281-288
Published online on: 01 January 2011

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Article

Side population in MDA-MB-231 human breast cancer cells exhibits cancer stem cell-like properties without higher bone-metastatic potential

Toru Hiraga, Susumu Ito, Hiroaki Nakamura
Pages: 289-296
Published online on: 01 January 2011

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Journal Cover
May-2026 Volume 55 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

ZBTB7A promotes malignant phenotypes in ovarian cancer through transcriptional activation of CRLF1

Xiaobai Hao, Yu Chen
Article Number: 102
Published online on: 24 March 2026

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Article Open Access

MS4322 is a selective protein arginine methyltransferase 5 degrader with antitumor effects in cervical cancer cells

Rui Luo, Jingping Chen, Zhaojie Chen, Surong Wang, Tianfeng Liu, Yang Xu
Article Number: 101
Published online on: 24 March 2026

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Retraction Open Access

[Retracted] Roles of the SNHG7/microRNA‑9‑5p/DPP4 ceRNA network in the growth and 131I resistance of thyroid carcinoma cells through PI3K/Akt activation

Wanzhi Chen, Jichun Yu, Rong Xie, Tao Zhou, Chengfeng Xiong, Shuyong Zhang, Meijun Zhong
Article Number: 100
Published online on: 23 March 2026

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Article Open Access

Andrographis exerts antitumor effects and enhances 5‑FU efficacy via the alteration of ferroptosis‑related genes in esophageal squamous cell carcinoma

Kosuke Yoshimura, Tadanobu Shimura, Ruiya Ma, Yaxuan Huang, Takahito Kitajima, Shinji Yamashita, Yuki Sato, Koki Higashi, Mikio Kawamura, Hiromi Yasuda, Yuhki Koike, Yoshiki Okita, Shigeyuki Yoshiyama, Minako Kobayashi, Masaki Ohi, Hiroki Ohge, Shinya Takahashi, Ajay Goel, Yoshinaga Okugawa, Yuji Toiyama
Article Number: 99
Published online on: 20 March 2026

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Article Open Access

Sphingosine‑1‑phosphate receptor 1 enhances olfactory receptor 51E1‑mediated inhibition of proliferation via Src/JNK signaling in prostate cancer cells

Kiheon Kim, Jinwoo Lee, Chulwon Choi, Jungnam Bae, Hee-Jung Choi, Won-Ki Huh
Article Number: 98
Published online on: 19 March 2026

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Review Open Access

Mechanistic insights into the roles of astragalosides and Astragalus polysaccharides in gynecological and breast cancers (Review)

Ruixin Liu, Zhanyu Lin, Yuelin Li, Yuetong Ci, Zhengqi Guo, Zhenguo Xu
Article Number: 97
Published online on: 19 March 2026

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Retraction Open Access

[Retracted] Inhibition of tankyrase 1 in human gastric cancer cells enhances telomere shortening by telomerase inhibitors 

Hao Zhang, Meng-Hua Yang, Jing-Jing Zhao, Ling Chen, Song-Tao Yu, Xu-Dong Tang, Dian-Chun Fang, Shi-Ming Yang
Article Number: 96
Published online on: 16 March 2026

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Article Open Access

Silencing of SIVA‑1 promotes cisplatin resistance in gastric cancer via the Bcl‑2/BAX‑mediated mitochondria‑dependent apoptosis pathway

Zheng-Yi Shi, Zheng-Rong Ding, Yu-Liang Huang, Yuan-Rui Lei, Hai-Bin Huang, Yan Qing, Miao-Ren Deng, Xu-Man Lu, Xu-Dong Dong, Long-Jie Xia, Sheng Xu, Xiao-Gang Zhong, Lei Li, Fan-Biao Kong, Xiao-Tong Wang
Article Number: 95
Published online on: 13 March 2026

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Article Open Access

Depleting HIF‑1α attenuates the progression of osteosarcoma, but tumorigenicity is sustained through HIF‑independent pathways

Ayaka Kunishima, Takatsune Shimizu, Tetsuya Takimoto, Atsunobu Sagara, Hiroyuki Nobusue, Hidetoshi Hasuwa, Shinya Hasegawa, Yuka Tamaoki, Hitomi Miyake, Yumi Fukuchi, Hideyuki Saya, Akihiro Muto
Article Number: 94
Published online on: 12 March 2026

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Article Open Access

Unveiling the role of ANGPT2 in esophageal cancer: A prognostic factor and potential oncogene

Zhigang Zhai, Zhenyu Xue, Yuan Fang, Yixu Fan, Shijiao Li, Yunpeng Yu, Chuansheng Chen, Kaijun Zhang, Deyu Chen, Xiang Tang, Rui Ling
Article Number: 93
Published online on: 12 March 2026

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Article Open Access

POLQ promotes tumor progression and immunosuppression via ATM‑P53 signaling in endometrial cancer

Ningning Zhu, Juanjuan Wang, Xiaoli Zhang, Kai Tang, Lei Gong, Yi Hu
Article Number: 92
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate and sodium citrate target glycolysis, suppress survivin, and induce mitochondrial‑mediated apoptosis in gastric cancer cells and inhibit gastric orthotopic transplantation tumor growth

Ting-An Wang, Xiao-Dong Zhang, Xing-Yu Guo, Shu-Lin Xian, Yun-Fei Lu
Article Number: 91
Published online on: 11 March 2026

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Review Open Access

Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review)

Zidong Xia, Huishan Zhai, Lei Zheng, Cheng Wang
Article Number: 90
Published online on: 09 March 2026

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Retraction Open Access

[Retracted] Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine‑γ‑lyase function

Liangyu Chen, Xinxing Li, Libo Liu, Bo Yu, Yixue Xue, Yunhui Liu
Article Number: 89
Published online on: 09 March 2026

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Review Open Access

Advances in the application of frailty scoring in the diagnosis and management of elderly patients with multiple myeloma (Review)

Junlun Liu, Danyu Li, Chao Li, Zhuoren Chen
Article Number: 88
Published online on: 06 March 2026

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Expression of Concern Open Access

[Expression of Concern] c‑Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma 

Lei You, Xiaoxia Ren, Yongxing Du, Wenjing Zhao, Ming Cui, Ge Chen, Yupei Zhao
Article Number: 87
Published online on: 05 March 2026

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Review Open Access

CXCL1 in triple‑negative breast cancer: Mechanisms, challenges, and therapeutic opportunities (Review)

Hiba Al Sayegh, Zahraa Assi, Amjad Kanaan, Mirvat El Sibai
Article Number: 86
Published online on: 03 March 2026

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Article Open Access

Cellular and inflammatory characteristics of patient‑derived glioblastoma organoids during in vitro cultivation

Jessica Nojszewski, Nils Oliver Schröder, Jacqueline Clüver, Jonna Holler, Hajrullah Ahmeti, Michael Synowitz, Janka Held-Feindt
Article Number: 85
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Growth and differentiation factor‑9 promotes adhesive and motile capacity of prostate cancer cells by up‑regulating FAK and Paxillin via Smad dependent pathway 

Sivan M. Bokobza, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Article Number: 84
Published online on: 02 March 2026

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Article Open Access

Platycodin D sensitizes head and neck squamous cell carcinoma to cisplatin by inducing autophagy arrest

Minji Bae, Min Kyeong Lee, Mi Gyeong Jeong, Yeonseo Lee, Harim Joo, Young Chan Lee, Jung Woo Lee, Su Il Kim, Seong-Gyu Ko, Young-Gyu Eun
Article Number: 83
Published online on: 27 February 2026

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Article Open Access

ACSBG1‑driven lipid reprogramming unveiled: A fatty acid metabolism‑associated prognostic model for lung adenocarcinoma

Panxin Hu, Anan Li
Article Number: 82
Published online on: 27 February 2026

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Article Open Access

Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation

Chao Li, Lei Yang, Yudong Zhang, Baocheng Zhao, Hao Qu
Article Number: 81
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways

Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang
Article Number: 80
Published online on: 25 February 2026

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Journal Cover
June-2026 Volume 55 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Expression of Concern Open Access

[Expression of Concern] 5‑Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene

Xiaorong Wang, E. Chen, Xue Yang, Yin Wang, Zhen Quan, Xiaohou Wu, Chunli Luo
Article Number: 103
Published online on: 30 March 2026

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