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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2012 Volume 27 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

The PI3K/Akt inhibitor LY294002 reverses BCRP-mediated drug resistance without affecting BCRP translocation

Yasuo Imai, Mayumi Yoshimori, Kazunori Fukuda, Hidetsugu Yamagishi, Yoshihiko Ueda
Pages: 1703-1709
Published online on: 15 March 2012

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Article Open Access

EPHX1 polymorphisms do not modify esophageal carcinoma susceptibility in Dutch Caucasians

Polat Dura, Caro V.V. Bregitha, Rene H.M. Te Morsche, Hennie M.J. Roelofs, Jon O. Kristinsson, Theo Wobbes, Ben J.M. Witteman, Adriaan C.I.T.L. Tan, Joost P.H. Drenth, Wilbert H.M. Peters
Pages: 1710-1716
Published online on: 19 March 2012

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Article Open Access

The accumulation of DNA demethylation in Sat α in normal gastric tissues with Helicobacter pylori infection renders susceptibility to gastric cancer in some individuals

Masaaki Saito, Koichi Suzuki, Takafumi Maeda, Takaharu Kato, Hidenori Kamiyama, Kei Koizumi, Yuichiro Miyaki, Shinichiro Okada, Hirokazu Kiyozaki, Fumio Konishi
Pages: 1717-1725
Published online on: 12 March 2012

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Article Open Access

SRT1720, a SIRT1 activator, promotes tumor cell migration, and lung metastasis of breast cancer in mice

Kensuke Suzuki, Ryuji Hayashi, Tomomi Ichikawa, Shingo Imanishi, Toru Yamada, Minehiko Inomata, Toshiro Miwa, Shoko Matsui, Isao Usui, Masaharu Urakaze, Yuji Matsuya, Hirofumi Ogawa, Hiroaki Sakurai, Ikuo Saiki, Kazuyuki Tobe
Pages: 1726-1732
Published online on: 27 March 2012

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Article

Expression of Cav-1 in tumour cells, rather than in stromal tissue, may promote cervical squamous cell carcinoma proliferation, and correlates with high-risk HPV infection

Jun Sun, Jun Gao, Jun Bo Hu, Li Fang Fan, Xiao Bo Zhu, Roz Subahan, Hong Lei Chen
Pages: 1733-1740
Published online on: 28 February 2012

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Article

Prognostic significance of aquaporins in human biliary tract carcinoma

Shinichi Sekine, Yutaka Shimada, Takuya Nagata, Makoto Moriyama, Tetsuya Omura, Tomoko Watanabe, Ryouta Hori, Isaku Yoshioka, Tomoyuki Okumura, Shigeaki Sawada, Junya Fukuoka, Kazuhiro Tsukada
Pages: 1741-1747
Published online on: 27 March 2012

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Article

Radiosensitizing effect of 5-aminolevulinic acid-induced protoporphyrin IX in glioma cells in vitro

Junkoh Yamamoto, Shun-Ichiro Ogura, Tohru Tanaka, Takehiro Kitagawa, Yoshiteru Nakano, Takeshi Saito, Mayu Takahashi, Daisuke Akiba, Shigeru Nishizawa
Pages: 1748-1752
Published online on: 28 February 2012

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Article

The cytotoxic effect of TGF-β1 on mesothelial cells via apoptosis in early peritoneal carcinomatosis

Zhi-Dong Lv, Zhao-Chuan Yang, Hai-Bo Wang, Jian-Guo Li, Bin Kong, Xin-Gang Wang, Xiao-Yi Liu, Zhao-He Niu, Yu Wang, Gang Nie
Pages: 1753-1758
Published online on: 19 March 2012

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Article

Clinicopathological and prognostic significance of microRNA-107 and its relationship to DICER1 mRNA expression in gastric cancer

Taisuke Inoue, Hisae Iinuma, Etsushi Ogawa, Tsuyoshi Inaba, Ryoji Fukushima
Pages: 1759-1764
Published online on: 07 March 2012

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Article

Interleukin-4 and CpG oligonucleotide therapy suppresses the outgrowth of tumors by activating tumor-specific Th1-type immune responses

Atsushi Kajiwara, Hiroyoshi Doi, Junichi Eguchi, Shigeaki Ishii, Ayako Hiraide-Sasagawa, Masashi Sakaki, Risa Omori, Kazumasa Hiroishi, Michio Imawari
Pages: 1765-1771
Published online on: 15 March 2012

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Article

Pheophorbide a-mediated photodynamic therapy induces apoptotic cell death in murine oral squamous cell carcinoma in vitro and in vivo

Mee-Young Ahn, Seong-Min Kwon, Yong-Chul Kim, Sang-Gun Ahn, Jung-Hoon Yoon
Pages: 1772-1778
Published online on: 27 March 2012

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Article

Dual inhibition of sphingosine kinase isoforms ablates TNF-induced drug resistance

James W. Antoon, Martin D. White, Matthew E. Burow, Barbara S. Beckman
Pages: 1779-1786
Published online on: 27 March 2012

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Article

Implications of cleaved caspase 3 and AIF expression in colorectal cancer based on patient age

Aurélie Perraud, Hussein Akil, Michelle Nouaille, Daniel Petit, François Labrousse, Marie-Odile Jauberteau, Muriel Mathonnet
Pages: 1787-1793
Published online on: 20 March 2012

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Article

Patients with peritoneal mesothelioma lack epidermal growth factor receptor tyrosine kinase mutations that would make them sensitive to tyrosine kinase inhibitors

Neetu Kalra, Ali Ashai, Liqiang Xi, Jingli Zhang, Itzhak Avital, Mark Raffeld, Raffit Hassan
Pages: 1794-1800
Published online on: 15 March 2012

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Article

Expression of high-risk HPV DNA and CK19 in pelvic lymph nodes in stage Ⅰa-Ⅱa cervical cancer and their clinical value

Fan Zhang, Dawo Liu, Bei Lin, Yingying Hao, Dan Zhou, Yue Qi, Shulan Zhang
Pages: 1801-1806
Published online on: 07 March 2012

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Article

Basic fibroblast growth factor in an animal model of spontaneous mammary tumor progression

Steven Kao, Jeffrey Mo, Andrew Baird, Brian P. Eliceiri
Pages: 1807-1814
Published online on: 07 March 2012

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Article

A unique MUC1-2-VNTR DNA vaccine suppresses tumor growth and prolongs survival in a murine multiple myeloma model

Yuhui Weng, Liang Shao, Hongmei Ouyang, Yuebo Liu, Jin Yao, Hong Yang, Yunjiao Luo, Hao Wang, Zhenyu Zhao, Hong Mou, Zeping Zhou, You Zhang
Pages: 1815-1822
Published online on: 07 March 2012

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Article

Antitumor effects of genetically engineered stem cells expressing yeast cytosine deaminase in lung cancer brain metastases via their tumor-tropic properties

Bo-Rim Yi, Seung U. Kim, Yun-Bae Kim, Hong Jun Lee, Myung-Haing Cho, Kyung-Chul Choi
Pages: 1823-1828
Published online on: 13 March 2012

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Article

Effects of silencing cyclooxygenase-2 expression via RNA interference on the tumorigenicity of the SMMC-7721 human hepatocarcinoma cell line

Li-Li Liu, Li-Rong Lin, Man-Li Tong, Zuo-Gen Fu, Gui-Li Liu, Wei-Hong  Zheng, Fan Liu, Dai-Wei Zhang, Zhong-Ying Zhang, Tian-Ci Yang
Pages: 1829-1834
Published online on: 28 February 2012

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Article

Tiam1, negatively regulated by miR-22, miR-183 and miR-31, is involved in migration, invasion and viability of ovarian cancer cells

Jun Li, Shanhui Liang, Hongyan Jin, Congjian Xu, Duan Ma, Xin Lu
Pages: 1835-1842
Published online on: 27 March 2012

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Article

Evaluation of MAGE A1 in oral squamous cell carcinoma

Cláudia Maria Pereira, Carolina Cavaliéri Gomes, Jeane De Fátima Correia Silva, Monica Bucciarelli Rodriguez, Alvimar Afonso Barbosa, Ricardo Santiago Gomez
Pages: 1843-1848
Published online on: 19 March 2012

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Article

Role of systemic chemotherapy in the management of resected or resectable colorectal liver metastases: a systematic review and meta-analysis of randomized controlled trials

Domenico Ciliberto, Ubaldo Prati, Laura Roveda, Vito Barbieri, Nicoletta Staropoli, Alberto Abbruzzese, Michele Caraglia, Massimo Di Maio, Domenico Flotta, Pierfrancesco Tassone, Pierosandro Tagliaferri
Pages: 1849-1856
Published online on: 22 March 2012

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Article

Apoptosis induced by 7-difluoromethoxyl-5,4'-di-n-octyl genistein via the inactivation of FoxM1 in ovarian cancer cells

Yingxia Ning, Qingxiu Li, Honglin Xiang, Fei Liu, Jianguo Cao
Pages: 1857-1864
Published online on: 22 March 2012

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Article

Tumorigenicity of cancer stem-like cells derived from hepatocarcinoma is regulated by microRNA-145

Yongsheng Jia, Honglin Liu, Qianshu Zhuang, Shiqing Xu, Zhihua Yang, Jianzhong Li, Jinning Lou, Wenjian Zhang
Pages: 1865-1872
Published online on: 28 February 2012

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Article

Luteinizing hormone facilitates angiogenesis in ovarian epithelial tumor cells and metformin inhibits the effect through the mTOR signaling pathway

Hong Liao, Qian Zhou, Yanqiong Gu, Tao Duan, Youji Feng
Pages: 1873-1878
Published online on: 27 March 2012

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Article

Role of PKC-ERK signaling in tamoxifen-induced apoptosis and tamoxifen resistance in human breast cancer cells

Zhihua Li, Na Wang, Jieyu Fang, Jintao Huang, Fen  Tian, Chaohong Li, Fukang Xie
Pages: 1879-1886
Published online on: 15 March 2012

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Article

Transcriptional upregulation of HER2 expression in the absence of HER2 gene amplification results in cetuximab resistance that is reversed by trastuzumab treatment

Cristina Oliveras-Ferraros, Anna Massaguer Vall-Llovera, Alejandro Vazquez-Martin, Dolors Carrion Salip, Bernardo Queralt, Silvia Cufí, Begoña Martin-Castillo, Joaquim Bosch-Barrera, Joan Brunet, Rafael De Llorens, Javier A. Menendez
Pages: 1887-1892
Published online on: 15 March 2012

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Article

Angiotensin II receptor type 1 blockers suppress the cell proliferation effects of angiotensin II in breast cancer cells by inhibiting AT1R signaling

Ning Du, Jiang Feng, Li-Juan Hu, Xin Sun, Hai-Bing Sun, Yang Zhao, Yi-Ping Yang, Hong Ren
Pages: 1893-1903
Published online on: 13 March 2012

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Article

The heat shock protein 90 inhibitor SNX-2112 inhibits B16 melanoma cell growth in vitro and in vivo

Kai-Sheng Liu, Wei-Chao Ding, Shao-Xiang Wang, Zhong Liu, Guo-Wen Xing, Ying Wang, Yi-Fei Wang
Pages: 1904-1910
Published online on: 22 March 2012

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Article

Involvement of Mcl1 in diallyl disulfide-induced G2/M cell cycle arrest in HL-60 cells

Lan Yi, Xiao-Xia Ji, Hui Tan, Mei-Yan Feng, Yi Tang, Ling Wen, Qi Su
Pages: 1911-1917
Published online on: 28 February 2012

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Article

NRF2 is overexpressed in ovarian epithelial carcinoma and is regulated by gonadotrophin and sex-steroid hormones

Hong Liao, Qian Zhou, Zhenbo Zhang, Qianqian Wang, Yunyan Sun, Xiaofang Yi, Youji Feng
Pages: 1918-1924
Published online on: 28 February 2012

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Article

In vivo and in situ imaging of head and neck squamous cell carcinoma using near-infrared fluorescent quantum dot probes conjugated with epidermal growth factor receptor monoclonal antibodies in mice

Kai Yang, Cheng Zhao, Yu-An Cao, Hong Tang, Yun-Long Bai, Hao Huang, Chuen-Rong Zhao, Rui Chen, Dan Zhao
Pages: 1925-1931
Published online on: 29 February 2012

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Article

A new bioinformatics insight into human cancer-associated proteins

Fu-Jun Liu, Xiu-Feng Hua, Wen-Juan Wang
Pages: 1932-1936
Published online on: 12 March 2012

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Article

Real-time bioluminescence and tomographic imaging of gastric cancer in a novel orthotopic mouse model

Hao Hu, Junting Liu, Liping Yao, Jipeng Yin, Ning Su, Xiangqiang Liu, Feng Cao, Jimin Liang, Yongzhan Nie, Kaichun Wu
Pages: 1937-1943
Published online on: 07 March 2012

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Article

The effect of NET-1 on the proliferation, migration and endocytosis of the SMMC-7721 HCC cell line

Gui-Lan Wang, Li Chen, Ying-Ze Wei, Jia-Ming Zhou, Yuan-Yuan Wu, Yi-Xin Zhang, Jing Qin, Yuan-Yuan Zhu
Pages: 1944-1952
Published online on: 28 February 2012

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Article

The expression of ARHI in pT2a and pT2b stage gastric cancer and its clinical significance

Wei Wang, Xian-Min Bu, Jian Wang, Ning Zhang, Cheng-Hai Zhao
Pages: 1953-1959
Published online on: 15 March 2012

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Article

microRNA-155 is downregulated in gastric cancer cells and involved in cell metastasis

Cheng-Long Li, Hui Nie, Ming Wang, Li-Ping Su, Jian-Fang Li, Ying-Yan Yu, Min Yan, Qin-Long Qu, Zheng-Gang Zhu, Bing-Ya Liu
Pages: 1960-1966
Published online on: 13 March 2012

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Article

microRNA-133 inhibits cell proliferation, migration and invasion in prostate cancer cells by targeting the epidermal growth factor receptor

Jun Tao, Deyao Wu, Bin Xu, Weichun Qian, Pengchao Li, Qiang Lu, Changjun Yin, Wei Zhang
Pages: 1967-1975
Published online on: 07 March 2012

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Article

Jolkinolide B induces apoptosis in MDA-MB-231 cells through inhibition of the PI3K/Akt signaling pathway

Yu Lin, Hongxia Cui, Huiyu Xu, Liling Yue, Hao Xu, Liyan Jiang, Jicheng Liu
Pages: 1976-1980
Published online on: 12 March 2012

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Article

Establishment of a bioluminescent MDA-MB-231 cell line for human triple-negative breast cancer research

Ke Wang, Simei Xie, Yu Ren, Haibin Xia, Xinwei Zhang, Jianjun He
Pages: 1981-1989
Published online on: 22 March 2012

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Article

Overexpression of HIF-1α in primary gallbladder carcinoma and its relation to vasculogenic mimicry and unfavourable prognosis

Wei Sun, Zhen-Yu Shen, Hui Zhang, Yue-Zu Fan, Wen-Zhong Zhang, Jing-Tao Zhang, Xing-Sui Lu, Chun Ye
Pages: 1990-2002
Published online on: 27 March 2012

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Article

CD147 silencing via RNA interference reduces tumor cell invasion, metastasis and increases chemosensitivity in pancreatic cancer cells

Yuqin Pan, Bangshun He, Guoqi Song, Qian Bao, Zhipeng Tang, Fuliang Tian, Shukui Wang
Pages: 2003-2009
Published online on: 15 March 2012

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Article

Livin mediates tumor cell invasion in the DU-145 cell line via NF-κB

Feng Chen, Deyong Yang, Xiangyu Che, Jianbo Wang, Xiancheng Li, Zhiwei Zhang, Xiaochi Chen, Xishuang Song
Pages: 2010-2016
Published online on: 15 March 2012

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Article

Expression of estrogen receptor β1 in colorectal cancer: Correlation with clinicopathological variables

Lea Rath-Wolfson, Ofer Purim, Edward Ram, Sara Morgenstern, Rumelia Koren, Baruch Brenner
Pages: 2017-2022
Published online on: 07 March 2012

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Article

Docosahexaenoic acid sensitizes colon cancer cells to sulindac sulfide-induced apoptosis

Soo-Jeong Lim, Eunmyong Lee, Eun-Hye Lee, Soo-Yeon Kim, Jun Hyung Cha, Hwanho Choi, Wanseo Park, Hyeon Kyeom Choi, Seong-Hee Ko, So Hee Kim
Pages: 2023-2030
Published online on: 06 March 2012

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Article

Evidence that aberrant protein metabolism contributes to chemoresistance in multiple myeloma cells

Richard K. Sipes, Xue Xia, Brian S. Lewis, Nicholas E. Burgis
Pages: 2031-2038
Published online on: 12 March 2012

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Article

Type II cGMP-dependent protein kinase inhibits EGF-induced MAPK/JNK signal transduction in breast cancer cells

Ting Lan, Yongchang Chen, Jianrong Sang, Yan Wu, Ying Wang, Lu Jiang, Yan Tao
Pages: 2039-2044
Published online on: 15 March 2012

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Article

Rab15 alternative splicing is altered in spheres of neuroblastoma cells

Thi Van Huyen Pham, Tri Budi Hartomo, Myeong Jin Lee, Daiichiro Hasegawa, Toshiaki Ishida, Keiichiro Kawasaki, Yoshiyuki Kosaka, Tomoto Yamamoto, Satoru Morikawa, Nobuyuki Yamamoto, Ikuko Kubokawa, Takeshi  Mori, Tomoko Yanai, Akira Hayakawa, Yasuhiro Takeshima, Kazumoto Iijima, Masafumi Matsuo, Hisahide Nishio, Noriyuki Nishimura
Pages: 2045-2049
Published online on: 15 March 2012

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Article

Resveratrol reverses temozolomide resistance by downregulation of MGMT in T98G glioblastoma cells by the NF-κB-dependent pathway

Huiyong Huang, Hong Lin, Xiang Zhang, Juan Li
Pages: 2050-2056
Published online on: 12 March 2012

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Article

Involvement of ER-α36, Src, EGFR and STAT5 in the biphasic estrogen signaling of ER-negative breast cancer cells

Xin-Tian Zhang, Ling Ding, Lian-Guo Kang, Zhao-Yi Wang
Pages: 2057-2065
Published online on: 15 March 2012

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Article

Effects of icotinib, a novel epidermal growth factor receptor tyrosine kinase inhibitor, in EGFR-mutated non-small cell lung cancer

Guangdie Yang, Yinan Yao, Jianya Zhou, Qiong Zhao
Pages: 2066-2072
Published online on: 22 March 2012

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Article

Prognostic significance of metadherin overexpression in hepatitis B virus-related hepatocellular carcinoma

Zhenbin Gong, Weihui Liu, Nan You, Tao Wang, Xing Wang, Peng Lu, Ge Zhao, Ping Yang, Desheng Wang, Kefeng Dou
Pages: 2073-2079
Published online on: 27 March 2012

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Article

Involvement of NF-κB-mediated expression of galectin-3-binding protein in TNF-α-induced breast cancer cell adhesion

Naruto Noma, Siro Simizu, Yusuke Kambayashi, Yasuaki Kabe, Makoto Suematsu, Kazuo Umezawa
Pages: 2080-2084
Published online on: 19 March 2012

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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