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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2003 Volume 11 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Deciphering the impaired cytokine cascades in chronic leg ulcers (Review)

Pascale Quatresooz, Frédérique Henry, Philippe Paquet, Claudine Pierard-Franchimont, Keith Harding, Gérald E. Pierard
Pages: 411-418
Published online on: 01 April 2003

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Induction of ATP-binding cassette A1 by all-trans retinoic acid: Possible role of liver X receptor-α

Dick Wågsäter, Jan Dimberg, Allan Sirsjö
Pages: 419-423
Published online on: 01 April 2003

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Persistent expression of the α1S-dihydropyridine receptor in aged human skeletal muscle: Implications for the excitation-contraction uncoupling hypothesis of sarcopenia

Michelle Ryan, Gillian Butler-Browne, Ida Erzen, Vincent Mouly, Lars-Eric Thornell, Anton Wernig, Kay Ohlendieck
Pages: 425-434
Published online on: 01 April 2003

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Article

A large deletion of the repeat site in semenogelin I is not involved in male infertility

Satetsu Miyano, Kaoru Yoshida, Miki Yoshiike, Chikara Miyamoto, Yasuhiro Furuichi, Teruaki Iwamoto
Pages: 435-440
Published online on: 01 April 2003

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Article

FHIT expression and hypermethylation in esophageal squamous cell carcinoma

Tsuyoshi Noguchi, Shinsuke Takeno, Yasuhiko Kimura, Yuzo Uchida, Tsutomu Daa, Shigeo Yokoyama, Helmut E. Gabbert, Wolfram Mueller
Pages: 441-447
Published online on: 01 April 2003

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Article

Influence of histochemical stains on quantitative gene expression analysis after laser-assisted microdissection

Ali-Fuat Okuducu, Viktor Janzen, Jens Claus Hahne, Yon Ko, Nicolas Wernert
Pages: 449-453
Published online on: 01 April 2003

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Article

Comparison of radiation-induced reactive oxygen species formation in adult articular chondrocytes and that in human peripheral T cells: Possible implication in radiosensitivity

Yasuhiro Ogawa, Toshiaki Takahashi, Toshihiro Kobayashi, Michio Toda, Akihito Nishioka, Shinji Kariya, Harumichu Seguchi, Hiroshi Yamamoto, Shoji Yoshida
Pages: 455-459
Published online on: 01 April 2003

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Article

Mutation of β-catenin and its protein accumulation in solid and cystic tumor of the pancreas associated with metastasis

Jiangyong Miao, Takeshi Kusafuka, Seika Kuroda, Akihiro Yoneda, Zhiwei Zhou, Akira Okada
Pages: 461-464
Published online on: 01 April 2003

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Article

Peptide mimotopes of oncoproteins as therapeutic agents in breast cancer

B. T. Ashok, L. David, Y. G. Chen, V. P.S. Garikapaty, B. Chander, D. Kanduc, A. Mittelman, R. K. Tiwari
Pages: 465-471
Published online on: 01 April 2003

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The HIP gene encoding a heparin/heparan sulfate interacting protein is mutated in metastatic human colorectal cancer

Yuxun Wang, Sandra Tan, Shing Chuan Hooi
Pages: 473-477
Published online on: 01 April 2003

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Reactive oxygen species and antioxidants in apoptosis of esophageal cancer cells induced by As2O3

Zhong-Ying Shen, Wen-Ying Shen, Ming-Hua Chen, Jian Shen, Yi Zeng
Pages: 479-484
Published online on: 01 April 2003

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Article

Telomeric repeat-length alterations in colorectal carcinoma are associated with loss of heterozygosity and point mutation in p53 gene

Shinji Ohki, Masamitsu Onda, Toshihiko Fukushima, Kenichi Takita, Shinichi Suzuki, Masami Hoshino, Atsuo Tsuchiya, Rikiya Abe, Seiichi Takenoshita
Pages: 485-490
Published online on: 01 April 2003

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Phospholipase C-γ1 is required for subculture-induced terminal differentiation of normal human oral keratinocytes

Ju-Eun Oh, Joong-Ki Kook, Kyung-Hee Park, Gene Lee, Byoung-Moo Seo, Byung-Moo Min
Pages: 491-498
Published online on: 01 April 2003

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Different apoptotic regulation of TRAIL-caspase pathway in HBV- and HCV-related hepatocellular carcinoma

Yoshihiko Yano, Yoshitake Hayashi, Miyuki Nakaji, Hidenobu Nagano, Yasushi Seo, Toshiaki Ninomiya, Seitetsu Yoon, Atushi Wada, Midori Hirai, Soo Ryang Kim, Hiroshi Yokozaki, Masato Kasuga
Pages: 499-504
Published online on: 01 April 2003

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Article

A novel mutation, 1234del(C), of the IRF6 in a Thai family with Van der Woude syndrome

Vorasuk Shotelersuk, Chalurmpon Srichomthong, Koh-Ichiro Yoshiura, Norio Niikawa
Pages: 505-507
Published online on: 01 April 2003

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Article

Purification by affinity chromatography of H1° RNA-binding proteins from rat brain

Maria Scaturrok, Anna Sala, Giuseppe Cutrona, Lavinia Raimondi, Giuseppe Cannino, Simona Fontana, Ida Pucci-Minafra, Italia Di Liegro
Pages: 509-513
Published online on: 01 April 2003

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Article

Molecular basis for the RhD negative phenotype in Chinese

Ching-Tien Peng, Mu-Chin Shih, Ta-Chih Liu, I-Ling Lin, San-Jang Jaung, Jan-Gowth Chang
Pages: 515-521
Published online on: 01 April 2003

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Article

A novel approach for immunization, screening and characterization of selected scFv libraries using membrane fractions of tumor cells

Mehmet Kemal Tur, Achim Rothe, Michael Huhn, Ute Goerres, Alexander Klimka, Michael Stöcker, Andreas Engert, Rainerr Fischer, Ricarda Finner, Stefan Barth
Pages: 523-527
Published online on: 01 April 2003

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Difference between Swedish and Japanese men in the association between AR CAG repeats and prostate cancer suggesting a susceptibility-modifying locus overlapping the androgen receptor gene

Chunde Li, Henrik Grönberg, Hideyasu Matsuyama, Günther Weber, Magnus Nordenskjöld, Katsusuke Naito, Anders Bergh, Ulf Bergerheim, Jan-Erik Damber, Catharina Larsson, Peter Ekman
Pages: 529-533
Published online on: 01 April 2003

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Article

Differential effects of fluoxetine enantiomers in mammalian neural and cardiac tissues

János Magyar, Zoltán Rusznák, Csaba Harasztosi, Ágnes Körtvély, Pál Pacher, Tamás Bányász, Csaba Pankucsi, László Kovács, Géza Szûcs, Péter P. Nánási, Valéria Kecskeméti
Pages: 535-542
Published online on: 01 April 2003

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Journal Cover
August-2026 Volume 58 Issue 2

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Myokines in exercise‑mediated bone homeostasis: Molecular signaling mechanisms and therapeutic implications for bone disorders (Review)

Bin Tian, Xuesong Chen, Jiang Zheng, Xin Kang
Article Number: 231
Published online on: 24 June 2026

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Review Open Access

Neutrophil extracellular traps in thrombosis of hematologic malignancies: Underlying mechanisms and therapeutic opportunities (Review)

Kebing Lv, Zijie Ma, Qiuni Chen, Yang Su, Jingjing Ma, Chunling Wang, Liang Yu
Article Number: 230
Published online on: 23 June 2026

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Recombinant myonectin ameliorates sepsis‑induced cardiomyopathy by alleviating mitochondrial dysfunction via the AdipoR1/AMPK pathway

Peipei Li, Rui Chen, Hanmo Zhang, Lihong Li, Huiling Luo, Beibei Du, Ping Yang
Article Number: 229
Published online on: 23 June 2026

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MTA2: Decoding pathogenic mechanisms, clinical implications and therapeutic frontiers across disease landscapes (Review)

Hao Xie, Ling Chen, Jing Gou, Xuehong Long, Ya Yang, Hai Hu, Ping Wu, Qibing Yan, Yongkang Wu
Article Number: 228
Published online on: 22 June 2026

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Mitochondria‑endoplasmic reticulum contact site nexus: Molecular integration, disease pathogenesis and therapeutic opportunities (Review)

Yi Liu, Xianda Che, Wei Wei, Chong Teng, Huimin Li
Article Number: 227
Published online on: 22 June 2026

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Metabolic messengers from the gut to the joint: Toward precision management of osteoarthritis (Review)

Ruipu Zhang, Liang Zhang, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 226
Published online on: 22 June 2026

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Retraction Open Access

[Retracted] Protection of telomeres 1 protein levels are associated with telomere length in gastric cancer

Kiyomu Fujii, Tomonori Sasahira, Yukiko Moriwaka, Naohide Oue, Wataru Yasui, Hiroki Kuniyasu
Article Number: 225
Published online on: 22 June 2026

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Molecular mechanism of hydromorphone preconditioning in cerebral ischemia/reperfusion‑induced inflammatory injury

Jing Yao, Zeqing Huang, Songze Li, Minghui Lun, Jianing Fan
Article Number: 224
Published online on: 18 June 2026

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Oridonin ameliorates ulcerative colitis by regulating the PI3K/AKT/mTOR signaling pathway to activate autophagy

Zhongxing Miao, Baohong Liu, Xingzhi Zhou, Mengru Lu, Ni Jia, Huamin Zhang, Ying Qi, Xiaoyu Tan, Qinggao Zhang
Article Number: 223
Published online on: 18 June 2026

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Article

Arsenic exposure and skin cancer: Mechanisms, clinical evidence and public health implications (Review)

Dimitrios A. Andreikos, Michael Aschner, Dimitrios C. Ziogas, Aristidis Tsatsakis, Demetrios A. Spandidos
Article Number: 222
Published online on: 18 June 2026

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Targeting glutathione metabolism for tumor radiosensitization (Review)

Haonan Xu, Meng Du, Xiaowen Liang, Xilin Xiao, Zhiyi Chen
Article Number: 221
Published online on: 16 June 2026

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Review Open Access

Effects of exercise‑derived extracellular vesicles: Epigenetic regulatory mechanisms and protective roles (Review)

Xinxin Zhang, Biao Zhang
Article Number: 220
Published online on: 15 June 2026

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Article Open Access

Moderate downregulation of NDUFA13 promotes cardiomyocytes proliferation and heart regeneration through the glycolysis/c‑Myc/Ccnd1 axis

Ying Gao, Ningjing Qian, Junyan Jin, Jiayi Liu, Bingqi Wang, Yaping Wang
Article Number: 219
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] (‑)‑Epigallocatechin‑3‑gallate attenuates myocardial injury induced by ischemia/reperfusion in diabetic rats and in H9c2 cells under hyperglycemic conditions

Yang Wu, Zhong-Yuan Xia, Bo Zhao, Yan Leng, Juan Dou, Qing-Tao Meng, Shao-Qing Lei, Zhi-Ze Chen, Jie Zhu
Article Number: 218
Published online on: 10 June 2026

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Article Open Access

Melatonin ameliorates circadian rhythm disruption induced erectile dysfunction by inhibiting oxidative stress mediated pyroptosis via Nrf2/HO‑1 axis

Qingtao Yang, Wei Li, Qi Yu, Jiang Shi, Lu Yang, Jun Qiao, Xi Wei, Changshi Gu, Fa Sun, Tao Li
Article Number: 217
Published online on: 09 June 2026

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Spatial architecture of immunometabolism: Mitochondrial‑organelle interfaces in immune signaling (Review)

Yaping Wu, Hao Yu, Ling Xia, Li Yang, Yu Zhou, Qian Yu
Article Number: 216
Published online on: 08 June 2026

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Review Open Access

Urea cycle dysregulation and arginine pathways in the pathogenesis of NAFLD and NASH (Review)

Boying Zhu, Chaoyang Wang, Peng Liu, Zhifeng Qu, Ran Qi, Shengjiang Chen, Huanzhang Niu
Article Number: 215
Published online on: 08 June 2026

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Article Open Access

Withaferin A, a candidate drug for lupus nephritis, confers renal protection via Pon1‑mediated attenuation of oxidative stress

Miao Xue, Junshuai Feng, Xiaorong Mao
Article Number: 214
Published online on: 08 June 2026

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Retraction Open Access

[Retracted] Classical dendritic cells regulate acute lung inflammation and injury in mice with lipopolysaccharide‑induced acute respiratory distress syndrome

Lang Li, Liang Dong, Dan Zhao, Fei Gao, Jie Yan
Article Number: 213
Published online on: 08 June 2026

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Review Open Access

Plant‑derived natural products alleviate dexamethasone‑induced skeletal muscle atrophy by modulating FoxO (Review)

Wei Dai, Jiabin Wu, Xiaotong Ma, Mingyu Wu, Ke Li, Haoyang Gao, Wenhong Wang, Weihua Xiao
Article Number: 212
Published online on: 05 June 2026

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Review Open Access

Functional hydrogels in cardiovascular therapy: Design, applications and clinical challenges (Review)

Zheming Yang, Jiayin Li, Lingxiao Zhao, Dali Zhang, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 211
Published online on: 04 June 2026

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Review Open Access

Experimental rodent models of cardiorenal syndrome types 3 and 4: Insights and clinical relevance (Review)

Stefanny M. Figueroa, Siyi Huang, Javier Reyes‑Osorio, Jean-Jacques Boffa, Cristián A. Amador, Christos E. Chadjichristos, Louis Boutin
Article Number: 210
Published online on: 04 June 2026

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Expression of Concern Open Access

[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes

Zhanli Yang, Chuntao Yang, Liangcan Xiao, Xinxue Liao, Aiping Lan, Xiuyu Wang, Ruixian Guo, Peixi Chen, Chengheng Hu, Jianqiang Feng
Article Number: 209
Published online on: 03 June 2026

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Article Open Access

Microbiota‑derived indole‑3‑propionic acid reprograms bone marrow stem cell fate via PPARγ suppression to rescue osteoporosis

Jinwu Bai, Ruideng Wang, Jixing Fan, Shilong Su, Gao Si, Qinyong You, Ao Sun, Daole Hu, Shan Gao, Yang Lv, Fang Zhou
Article Number: 208
Published online on: 03 June 2026

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Article Open Access

Lactate regulates osteoclastogenesis via H3k18la in osteoarthritis

Zhibo Fan, Qiyue Fu, Tao Sun, Yutong Zhong, Yuefan Ma, Jingwei Jian, Shuosheng Yuan, Shenghong Li, Xiaomei Xu
Article Number: 207
Published online on: 02 June 2026

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Retraction Open Access

[Retracted] miR‑215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancert

Xiaoxu Gao, Yan Cai, Ruifang An
Article Number: 206
Published online on: 02 June 2026

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Review

Multi‑scale experimental models for the study of angiogenesis (Review)

Qin Yu, Jiarui Hu, Shuangshuang Yuan, Jiexia Gan, Mao Luo, Jianbo Wu, Liqun Wang
Article Number: 205
Published online on: 28 May 2026

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Targeting lactylation in hepatocellular carcinoma: Mechanistic insights and therapeutic opportunities (Review)

Lianting Chen, Feiqiong Gao, Qianru Mei, Yujie Li, Qun Cai, Xudong Feng
Article Number: 204
Published online on: 28 May 2026

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Article Open Access

Oxygen‑sensing histone demethylase KDM6A modulates chondrocyte‑to‑osteoblast transdifferentiation by activating the Wnt/β‑catenin pathway

Yi Rong, Hao Yu, Heng Yin, Shaoshuo Li, Jianwei Wang, Zhongyuan Shen, Xinxin Ding, Fanchen Bu, Tianyi Dai, Gean Wu, Zhen Hua
Article Number: 203
Published online on: 28 May 2026

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Journal Cover
September-2026 Volume 58 Issue 3

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Skeletal muscle‑derived extracellular vesicles in multi‑organ degenerative disease: Mechanisms and therapeutic delivery perspectives (Review)

Xianji Wei, Chengyan Guo, Wei Zhang, Guanyi Wang, Wenjing Li, Binghong Gao, Bo Gao, Lingli Zhang
Article Number: 232
Published online on: 26 June 2026

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