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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2005 Volume 27 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Genomic imbalances in human leukemia and lymphoma detected by comparative genomic hybridization (Review)

Erich Gebhart
Pages: 593-606
Published online on: 01 September 2005

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Article

Are syngeneic mouse tumor models still valuable experimental models in the field of anti-cancer drug discovery?

Francis Darro, Christine Decaestecker, Jean-François Gaussin, Steven Mortier, Rob Van Ginckel, Robert Kiss
Pages: 607-616
Published online on: 01 September 2005

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Article

Heparanase, TrkC and p75NTR: Their functional involvement in human medulloblastoma cell invasion

Neeta D. Sinnappah-Kang, Adam J. Kaiser, Bryan E. Blust, Robert E. Mrak, Dario Marchetti
Pages: 617-626
Published online on: 01 September 2005

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Article

Basic investigation on the development of molecular targeting therapy against cyclin-dependent kinase inhibitor p27Kip1 in head and neck cancer cells

Supriatno, Koji Harada, Hideo Yoshida, Mitsunobu Sato
Pages: 627-635
Published online on: 01 September 2005

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Article

Efficacy of intraperitoneal chemotherapy with paclitaxel targeting peritoneal micrometastasis as revealed by GFP-tagged human gastric cancer cell lines in nude mice

Norifumi Ohashi, Yasuhiro Kodera, Hayao Nakanishi, Hiroyuki Yokoyama, Michitaka Fujiwara, Masahiko Koike, Kenji Hibi, Akimasa Nakao, Masae Tatematsu
Pages: 637-644
Published online on: 01 September 2005

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Article

Correlation of translocation of tight junction protein Zonula occludens-1 and activation of epidermal growth factor receptor in the regulation of invasion of pancreatic cancer cells

Eiji Takai, Xiaodong Tan, Yasuhiko Tamori, Masahiko Hirota, Hiroshi Egami, Michio Ogawa
Pages: 645-651
Published online on: 01 September 2005

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Article

Synthetic chenodeoxycholic acid derivatives inhibit glioblastoma multiform tumor growth in vitro and in vivo

Su-Bog Yee, Won Jae Yeo, Bong Soo Park, Ji Young Kim, Soo Jin Baek, Yoon Cheong Kim, Su Young Seo, Sang Hwa Lee, Jae Hong Kim, Hongsuk Suh, Nam Deuk Kim, Young Jin Lim, Young Hyun Yoo
Pages: 653-659
Published online on: 01 September 2005

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Article

Patterns of expression of cytochrome P450 genes in progression of hepatitis C virus-associated hepatocellular carcinoma

Ryouichi Tsunedomi, Norio Iizuka, Yoshihiko Hamamoto, Shunji Uchimura, Takanobu Miyamoto, Takao Tamesa, Toshimasa Okada, Norikazu Takemoto, Motonari Takashima, Kazuhiko Sakamoto, Kenji Hamada, Hisafumi Yamada-Okabe, Masaaki Oka
Pages: 661-667
Published online on: 01 September 2005

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Article

Vascular endothelial growth factor-D induces lymphangiogenesis and lymphatic metastasis in models of ductal pancreatic cancer

Zofia Von Marschall, Arne Scholz, Steven A. Stacker, Marc G. Achen, David G. Jackson, Frauke Alves, Michael Schirner, Martin Haberey, Karl-Heinz Thierauch, Bertram Wiedenmann, Stefan Rosewicz
Pages: 669-679
Published online on: 01 September 2005

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Article

Suppression of tumor growth in human gastric cancer with HER2 overexpression by an anti-HER2 antibody in a murine model

Yoko Matsui, Masafumi Inomata, Manabu Tojigamori, Kazuya Sonoda, Norio Shiraishi, Seigo Kitano
Pages: 681-685
Published online on: 01 September 2005

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Article

Comparison between triple therapy with octreotide, galanin and serotonin vs. irinotecan or oxaliplatin in combination with 5-fluorouracil/leukovorin in human colon cancer

M. El-Salhy, L. Hilding, H. Royson, V. Tjomsland
Pages: 687-691
Published online on: 01 September 2005

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Article

Plasminogen activator/plasmin system suppresses cell-cell adhesion of oral squamous cell carcinoma cells via proteolysis of E-cadherin

Yasutaka Hayashido, Tomoaki Hamana, Yukio Yoshioka, Hisataka Kitano, Koh-Ichi Koizumi, Tetsuji Okamoto
Pages: 693-698
Published online on: 01 September 2005

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Article

Subcellular localization of caspase-3 activation correlates with changes in apoptotic morphology in MOLT-4 leukemia cells exposed to X-ray irradiation

Yongdong Feng, Junbo Hu, Daxin Xie, Jichao Qin, Yisheng Zhong, Xiaolan Li, Wei Xiao, Jianhong Wu, Deding Tao, Manchao Zhang, Yunfeng Zhu, Yuping Song, Eddie Reed, Qingdi Q. Li, Jianping Gong
Pages: 699-704
Published online on: 01 September 2005

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Article

An in vivo tumor model expressing green fluorescent protein for the investigation of metastasis

Oliver Thews, Christine Lambert, Debra K. Kelleher, Hans K. Biesalski, Peter Vaupel, Juergen Frank
Pages: 705-712
Published online on: 01 September 2005

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Article

Extraction and processing of high quality RNA from impalpable and macroscopically invisible prostate cancer for microarray gene expression analysis

Thorsten Schlomm, Andreas M. Luebke, Holger Sültmann, Olaf J.C. Hellwinkel, Ulrich Sauer, Annemarie Poustka, Kerstin A. David, Felix K.H. Chun, Alexander Haese, Markus Graefen, Andreas Erbersdobler, Hartwig Huland
Pages: 713-720
Published online on: 01 September 2005

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Article

The effects of interleukin-7 on the lymphangiogenic properties of human endothelial cells

Mahir A.A. Al-Rawi, Gareth Watkins, Robert E. Mansel, Wen G. Jiang
Pages: 721-730
Published online on: 01 September 2005

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Article

Characterization of cell lines derived from tumors induced by TC-1 cells in mice preimmunized against HPV16 E7 oncoprotein

Michal Smahel, Jana Smahelová, Pavla Tejklová, Ruth Tachezy, Iuri Marinov
Pages: 731-742
Published online on: 01 September 2005

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Article

A putative role for histone deacetylase in the differentiation of human erythroid cells

Atsushi Fujieda, Naoyuki Katayama, Kohshi Ohishi, Kentaro Yamamura, Tetsunori Shibasaki, Yuka Sugimoto, Eri Miyata, Kazuhiro Nishi, Masahiro Masuya, Hirotsugu Ueda, Hidenori Nakajima, Hiroshi Shiku
Pages: 743-748
Published online on: 01 September 2005

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Article

Wound-induced migration of MDA-MB-435 and SKOV-3 cancer cells is regulated by plasminogen activator inhibitor-1

Brandi R. Whitley, Frank C. Church
Pages: 749-757
Published online on: 01 September 2005

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Article

Reduced excision repair cross-complementing 1 expression associates with enhanced papilloma formation and fibroblast transformation after genetic disruption of secreted protein acidic and rich in cysteine

Yasumasa Kato, Mamoru Tsukuda, Yoji Nagashima, Shinri Koshika, Naoki Sakai, Masahiro Yao, Yoshinobu Kubota, Ichiro Aoki, William H. Colledge, Jean-Michel Foidart, Ryu-Ichiro Hata, Erik W. Thompson
Pages: 759-768
Published online on: 01 September 2005

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Article

The effect of arsenicals on ultraviolet-radiation-induced growth arrest and related signaling events in human keratinocytes

Anuradha Mudipalli, Russell D. Owen, R. Julian Preston
Pages: 769-778
Published online on: 01 September 2005

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Article

Long-term clinical outcome of AIDS-related Kaposi's sarcoma during highly active antiretroviral therapy

Anna Maria Cattelan, Maria Luisa Calabrò, Anita De Rossi, Savina Maria Luciana Aversa, Massimo Barbierato, Marco Trevenzoli, Paola Gasperini, Marisa Zanchetta, Paolo Cadrobbi, Silvio Monfardini, Luigi Chieco-Bianchi
Pages: 779-785
Published online on: 01 September 2005

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Article

Increased level of the p67phox subunit of NADPH oxidase by 4HPR in head and neck squamous carcinoma cells

Hyun-Jung Kim, Nobuhiko Oridate, Reuben Lotan
Pages: 787-790
Published online on: 01 September 2005

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Article

Expression and activity of vascular endothelial growth factor and metalloproteinases in alveolar and embryonal rhabdomyosarcoma cell lines

Maurizio Onisto, M. Liliana Slongo, Laura Gregnanin, Tamara Gastaldi, Modesto Carli, Angelo Rosolen
Pages: 791-798
Published online on: 01 September 2005

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Article

NF-κB activation contributes to anthracycline resistance pathway in human ovarian carcinoma cell line A2780

Carmela Salvatore, Grazia Camarda, Carlo Alberto Maggi, Cristina Goso, Stefano Manzini, Monica Binaschi
Pages: 799-806
Published online on: 01 September 2005

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Article

Apoptosis, necrosis and hypoxia inducible factor-1 in human head and neck squamous cell carcinoma cultures

Johann Gross, Julia Fuchs, Astrid Machulik, Volker Jahnke, Thomas Kietzmann, Ulrike Bockmühl
Pages: 807-814
Published online on: 01 September 2005

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Article

Patient surveillance after curative-intent surgery for rectal cancer

Frank E. Johnson, Walter E. Longo, Kenichi Ode, Umar S. Shariff, Trifonas Papettas, Alaine E. McGarry, Steven R. Gammon, Paul A. Lee, Riccardo A. Audisio, Erik M. Grossmann, Katherine S. Virgo
Pages: 815-822
Published online on: 01 September 2005

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Article

Transient activation of EGFR/AKT cell survival pathway and expression of survivin contribute to reduced sensitivity of human melanoma cells to betulinic acid

Lihua Qiu, Qun Wang, Wen Di, Qin Jiang, Erica Schefeller, Steve Derby, Harold Wanebo, Bingfang Yan, Yinsheng Wan
Pages: 823-830
Published online on: 01 September 2005

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Article

The cellular response to ectopic overexpression of the tuberous sclerosis genes, TSC1 and TSC2: a proteomic approach

Markus Hengstschläger, Margit Rosner, Michael Fountoulakis, Gert Lubec
Pages: 831-838
Published online on: 01 September 2005

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Article

Emodin suppresses hyaluronic acid-induced MMP-9 secretion and invasion of glioma cells

Mi Suk Kim, Myung Jin Park, So Jeong Kim, Chang Hun Lee, Heon Yoo, Sang Hoon Shin, Eun Sook Song, Seung Hoon Lee
Pages: 839-846
Published online on: 01 September 2005

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Article

Mechanism of telomerase repression during terminal differentiation of normal epithelial cells and squamous carcinoma lines

David L. Crowe, Dan C. Nguyen, Arthur Ohannessian
Pages: 847-854
Published online on: 01 September 2005

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Article

Cancer cachexia results in an increase in TNF-α receptor gene expression in both skeletal muscle and adipose tissue

Maite Figueras, Sílvia Busquets, Neus Carbó, Vanessa Almendro, Josep M. Argilés, Francisco J. López-Soriano
Pages: 855-860
Published online on: 01 September 2005

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Article

Comparative genomics on Sfrp1 orthologs

Yuriko Katoh, Masaru Katoh
Pages: 861-865
Published online on: 01 September 2005

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Article

Glutamate receptor-mediated effects on growth and morphology of human histiocytic lymphoma cells

Helga Susanne E. Haas, Roswitha Pfragner, Veronika Siegl, Elisabeth Ingolic, Elfgard Heintz, Konrad Schauenstein
Pages: 867-874
Published online on: 01 September 2005

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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