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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2009 Volume 35 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Generation of an immortalized astrocyte cell line from H-2Kb-tsA58 mice to study the role of astrocytes in brain metastasis

Robert R. Langley, Dominic Fan, Lixia Guo, Chenyu Zhang, Qingtang Lin, Emily C. Brantley, Joseph H. McCarty, Isaiah J. Fidler
Pages: 665-672
Published online on: 01 October 2009

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Article Open Access

Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells

Masahiko Ajiro, Toyomasa Katagiri, Koji Ueda, Hidewaki Nakagawa, Chikako Fukukawa, Meng-Lay Lin, Jae-Hyun Park, Toshihiko Nishidate, Yataro Daigo, Yusuke Nakamura
Pages: 673-681
Published online on: 01 October 2009

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Article

Tumor proteomic profiling predicts the susceptibility of breast cancer to chemotherapy

Jianbo He, Dejun Shen, Debra U. Chung, Romaine E. Saxton, Julian P. Whitelegge, Kym F. Faull, Helena R. Chang
Pages: 683-692
Published online on: 01 October 2009

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Article

AsialoGM1 and integrin α2β1 mediate prostate cancer progression

Severine Van Slambrouck, John Hilkens, Marco Bisoffi, Wim F.A. Steelant
Pages: 693-699
Published online on: 01 October 2009

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Article

Clonal proliferation of HTLV-1-infected cells is associated with spontaneous malignant tumor formation in mice

Masakazu Tanaka, Takayuki Nitta, Toshinori Yoshida, Tomoko Konishi, Yusuke Kawazu, Jun-ichi Fujisawa, Masanao Miwa
Pages: 701-707
Published online on: 01 October 2009

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Article

Overexpression of the signal peptide whirlin isoform 2 is related to disease progression in colorectal cancer patients

Yuji Toiyama, Akira Mizoguchi, Kazushi Kimura, Junichirou Hiro, Tomonari Tutsumi, Yasuhiro Inoue, Chikao Miki, Masato Kusunoki
Pages: 709-715
Published online on: 01 October 2009

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Article

Mitochondrial-dependent caspase activation pathway is involved in baicalein-induced apoptosis in human hepatoma J5 cells

Hsiu-Maan Kuo, Hung-Chieh Tsai, Ya-Ling Lin, Jai-Sing Yang, An-Cheng Huang, Mei-Due Yang, Shu-Chun Hsu, Meng-Chin Chung, W. Gibson Wood, Jing-Gung Chung
Pages: 717-724
Published online on: 01 October 2009

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Article

Cetuximab inhibits growth, peritoneal dissemination, and lymph node and lung metastasis of endometrial cancer, and prolongs host survival

Kayoko Takahashi, Yasushi Saga, Hiroyuki Mizukami, Yuji Takei, Shizuo Machida, Hiroyuki Fujiwara, Keiya Ozawa, Mitsuaki Suzuki
Pages: 725-729
Published online on: 01 October 2009

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Article

Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility

Nicholas Gulati, Michael Karsy, Ladislau Albert, Raj Murali, Meena Jhanwar-Uniyal
Pages: 731-740
Published online on: 01 October 2009

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Article

Blockade of B7-H1 or B7-DC induces an anti-tumor effect in a mouse pancreatic cancer model

Keisuke Okudaira, Ryota Hokari, Yoshikazu Tsuzuki, Yoshikiyo Okada, Shunsuke Komoto, Chikako Watanabe, Chie Kurihara, Atsushi Kawaguchi, Shigeaki Nagao, Miyuki Azuma, Hideo Yagita, Soichiro Miura
Pages: 741-749
Published online on: 01 October 2009

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Article Open Access

Enhanced expression of SOS1 is detected in prostate cancer epithelial cells from African-American men

Olga A. Timofeeva, Xueping Zhang, Habtom W. Ressom, Rency S. Varghese, Bhaskar VS. Kallakury, Kan Wang, Youngmi Ji, Amrita Cheema, Mira Jung, Milton L. Brown, Johng S. Rhim, Anatoly Dritschilo
Pages: 751-760
Published online on: 01 October 2009

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Article

Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM-mediated signalling pathways involving Cdc2 and γ-adducin

S. Matou-Nasri, J. Gaffney, S. Kumar, M. Slevin
Pages: 761-773
Published online on: 01 October 2009

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Article

Identification of chromosomal aberrations associated with disease progression and a novel 3q13.31 deletion involving LSAMP gene in osteosarcoma

Chueh-Chuan Yen, Wei-Ming Chen, Tain-Hsiung Chen, Winby York-Kwan Chen, Paul Chih-Hsueh Chen, Hong-Jen Chiou, Giun-Yi Hung, Hung-Ta Hondar Wu, Chao-Jung Wei, Cheng-Ying Shiau, Yu-Chung Wu, Ta-Chung Chao, Cheng-Hwai Tzeng, Po-Min Chen, Chi-Hung Lin, Yann-Jang Chen, Jonathan A. Fletcher
Pages: 775-788
Published online on: 01 October 2009

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Article

Triple-negative breast cancers express receptors for luteinizing hormone-releasing hormone (LHRH) and respond to LHRH antagonist Cetrorelix with growth inhibition

Stefan Buchholz, Stephan Seitz, Andrew V. Schally, Jörg B. Engel, Ferenc G. Rick, Luca Szalontay, Florian Hohla, Awtar Krishan, Andrea Papadia, Timo Gaiser, Gero Brockhoff, Olaf Ortmann, Klaus Diedrich, Frank Köster
Pages: 789-796
Published online on: 01 October 2009

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Article

Estimation of tumor microvessel density by MRI using a blood pool contrast agent

Fuminori Hyodo, Gadisetti V.R. Chandramouli, Shingo Matsumoto, Ken-ichiro Matsumoto, James B. Mitchell, Murali C. Krishna, Jeeva P. Munasinghe
Pages: 797-804
Published online on: 01 October 2009

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Article

A novel anti-tumor protein extracted from Meretrix meretrix Linnaeus induces cell death by increasing cell permeability and inhibiting tubulin polymerization

Xuanxuan Ning, Jianmin Zhao, Yuyan Zhang, Subing Cao, Ming Liu, Peixue Ling, Xiukun Lin
Pages: 805-812
Published online on: 01 October 2009

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Article

LIV-1 enhances the aggressive phenotype through the induction of epithelial to mesenchymal transition in human pancreatic carcinoma cells

Jun Unno, Kennichi Satoh, Morihisa Hirota, Atsushi Kanno, Shin Hamada, Hiromichi Ito, Atsushi Masamune, Nobukazu Tsukamoto, Fuyuhiko Motoi, Shinichi Egawa, Michiaki Unno, Akira Horii, Tooru Shimosegawa
Pages: 813-821
Published online on: 01 October 2009

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Article

Silencing of GRP94 expression promotes apoptosis in pancreatic cancer cells

Zheng Pan, Mert Erkan, Sylvia Streit, Helmut Friess, Jörg Kleeff
Pages: 823-828
Published online on: 01 October 2009

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Article

In vitro- and in vivo-targeted tumor lysis by an MMP2 cleavable melittin-LAP fusion protein

Lori Holle, Wen Song, Eric Holle, Yangzhang Wei, Jinhua Li, Thomas E. Wagner, Xianzhong Yu
Pages: 829-835
Published online on: 01 October 2009

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Article

The differential cell signaling effects of two positional isomers of the anticancer NO-donating aspirin

Amy Hua, Gerardo G. Mackenzie, Basil Rigas
Pages: 837-844
Published online on: 01 October 2009

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Article

Biological significance of EPHA2 expression in neuroblastoma

Bing Kung, Huaqing Zhao, Sakeenah L. Hicks, Xao X. Tang, Naohiko Ikegaki
Pages: 845-850
Published online on: 01 October 2009

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Article

RNAi-mediated downregulation of MMP-2 activates the extrinsic apoptotic pathway in human glioma xenograft cells

Christopher S. Gondi, Lavanya Talluri, Dzung H. Dinh, Meena Gujrati, Jasti S. Rao
Pages: 851-859
Published online on: 01 October 2009

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Article

SiRNA of Frizzled-9 suppresses proliferation and motility of hepatoma cells

Tatsuya Fujimoto, Minoru Tomizawa, Osamu Yokosuka
Pages: 861-866
Published online on: 01 October 2009

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Article

Curcumin analogue GO-Y030 inhibits STAT3 activity and cell growth in breast and pancreatic carcinomas

Brian Hutzen, Lauren Friedman, Matthew Sobo, Li Lin, Ling Cen, Stephanie De Angelis, Hiroyuki Yamakoshi, Hiroyuki Shibata, Yoshiharu Iwabuchi, Jiayuh Lin
Pages: 867-872
Published online on: 01 October 2009

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Article

Betulinic acid treatment promotes apoptosis in hepatoblastoma cells

M. Eichenmüller, D. von Schweinitz, R. Kappler
Pages: 873-879
Published online on: 01 October 2009

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Article

In vitro anti-inflammatory and anticancer activities of extracts of Acalypha alopecuroidea (Euphorbiaceae)

Sibylle Madlener, Jana Svacinová, Miloslav Kitner, Jirí Kopecky, Ruth Eytner, Andreas Lackner, Than Phuong Nha Vo, Richard Frisch, Michael Grusch, Rainer De Martin, Karel Dolezal, Miroslav Strnad, Georg Krupitza
Pages: 881-891
Published online on: 01 October 2009

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Article

A new phantom using polyethylene glycol as an apparent diffusion coefficient standard for MR imaging

Ryohei Matsuya, Masahiro Kuroda, Yoshitsugu Matsumoto, Hirokazu Kato, Hidenobu Matsuzaki, Junichi Asaumi, Jun Murakami, Kazunori Katashima, Masakazu Ashida, Takanori Sasaki, Tetsuro Sei, Kengo Himei, Kuniaki Katsui, Norihisa Katayama, Mitsuhiro Takemoto, Susumu Kanazawa, Seiichi Mimura, Seiichiro Oono, Takuichi Kitayama, Seiji Tahara, Keiji Inamura
Pages: 893-900
Published online on: 01 October 2009

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Article

Ribozyme to TGF-β1 mRNA abrogates immunosuppressive effects of human colorectal adenocarcinoma HRT-18 cells in vitro and in vivo

Wolfgang Daniel Schmitt, Antje Siegert, Sandra Stephanie Lach, Stephan Fuhrmann, Anke Kondla, Per Sonne Holm, Steffen Hauptmann
Pages: 901-908
Published online on: 01 October 2009

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Article

Efficacy of MS-275, a selective inhibitor of class I histone deacetylases, in human colon cancer models

Tomke Ute Bracker, Anette Sommer, Iduna Fichtner, Hortensia Faus, Bernard Haendler, Holger Hess-Stumpp
Pages: 909-920
Published online on: 01 October 2009

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Article Open Access

Time-resolved gene expression profiling of human squamous cell carcinoma cells during the apoptosis process induced by photodynamic treatment with hypericin

Renata Sanovic, Barbara Krammer, Sandra Grumboeck, Thomas Verwanger
Pages: 921-939
Published online on: 01 October 2009

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Article

DNA vaccination against bcr-abl-positive cells in mice

Vincent Lucansky, Eva Sobotkova, Ruth Tachezy, Martina Duskova, Vladimir Vonka
Pages: 941-951
Published online on: 01 October 2009

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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