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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2011 Volume 39 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Oligodendroglioma cells shed microvesicles which contain TRAIL as well as molecular chaperones and induce cell death in astrocytes

Alessandra Lo Cicero, Gabriella Schiera, Patrizia Proia, Patrizia Saladino, Giovanni Savettieri, Carlo Maria Di Liegro, Italia Di Liegro
Pages: 1353-1357
Published online on: 12 August 2011

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The potent peptide antagonist to angiogenesis, C16Y, and cisplatin act synergistically in the down-regulation of the Bcl-2/Bax ratio and the induction of apoptosis in human ovarian cancer cells

Akiko Shinagawa, Yoshio Yoshida, Tetsuji Kurokawa, Yuko Horiuchi, Hideaki Tsuyoshi, Makoto Orisaka, Yoko Sawamura, Hynda K. Kleinman, Fumikazu Kotsuji
Pages: 1359-1364
Published online on: 20 July 2011

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Article

Frequent deletion of 3p21.1 region carrying semaphorin 3G and aberrant expression of the genes participating in semaphorin signaling in the epithelioid type of malignant mesothelioma cells

Yoshie Yoshikawa, Ayuko Sato, Tohru Tsujimura, Tomonori Morinaga, Kazuya Fukuoka, Shusai Yamada, Aki Murakami, Nobuyuki Kondo, Seiji Matsumoto, Yoshitomo Okumura, Fumihiro Tanaka, Seiki Hasegawa, Tomoko Hashimoto-Tamaoki, Takashi Nakano
Pages: 1365-1374
Published online on: 12 August 2011

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Article

Ultra-violet irradiation induces apoptosis via mitochondrial pathway in pancreatic cancer cells

Takahiro Yamauchi, Seiji Adachi, Ichiro Yasuda, Masanori Nakashima, Junji Kawaguchi, Takashi Yoshioka, Yoshinobu Hirose, Osamu Kozawa, Hisataka Moriwaki
Pages: 1375-1380
Published online on: 05 September 2011

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Article

Antitumor and apoptosis-promoting properties of emodin, an anthraquinone derivative from Rheum officinale Baill, against pancreatic cancer in mice via inhibition of Akt activation

Wei-Τian Wei, Hui Chen, Zhong-Lin Ni, Hai-Βin Liu, Hong-Fei Tong, Ling Fan, An Liu, Mai-Χuan Qiu, Dian-Lei Liu, Hong-Chun Guo, Zhao-Hong Wang, Sheng-Zhang Lin
Pages: 1381-1390
Published online on: 29 July 2011

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Article

Increased ΔNp63 expression is predictive of malignant transformation in oral epithelial dysplasia and poor prognosis in oral squamous cell carcinoma

Ryota Matsubara, Shintaro Kawano, Takahiro Kiyosue, Yuichi Goto, Mitsuhiro Hirano, Teppei Jinno, Takeshi Toyoshima, Ryoji Kitamura, Kazunari Oobu, Seiji Nakamura
Pages: 1391-1399
Published online on: 09 August 2011

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Article

A novel function of EpCAM in oral squamous cell carcinoma cells under anchorage-independent conditions

Hiroshi Inoue, Yuichi Ohnishi, Masahiro Nakajima, Kenji Kakudo, Masami Nozaki
Pages: 1401-1405
Published online on: 22 July 2011

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Article

Regional therapy with DTA-H19 vector suppresses growth of colon adenocarcinoma metastases in the rat liver

Vladimir Sorin, Patricia Ohana, Aya Mizrahi, Imad Matouk, Tatiana Birman, Abraham Hochberg, Abraham Czerniak
Pages: 1407-1412
Published online on: 18 August 2011

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Prognostic impact of p53 aberrations for R-CHOP-treated patients with diffuse large B-cell lymphoma

Lenka Stefancikova, Mojmir Moulis, Pavel Fabian, Ingrid Vasova, Frantisek Zedek, Barbora Ravcukova, Jan Muzik, Petr Kuglik, Vladimira Vranova, Iva Falkova, Renata Hrabalkova, Jana Smardova
Pages: 1413-1420
Published online on: 18 August 2011

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Article

Chondroitin sulfate expression predicts poor outcome in breast cancer

Katrin J. Svensson, Helena C. Christianson, Paulina Kucharzewska, Victor Fagerström, Lars Lundstedt, Signe Borgquist, Karin Jirström, Mattias Belting
Pages: 1421-1428
Published online on: 17 August 2011

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Response to low-dose X-irradiation is p53-dependent in a papillary thyroid carcinoma model system

Khalil Abou-El-Ardat, Hanane Derradji, Winnok de Vos, Tim de Meyer, Sofie Bekaert, Wim van Criekinge, Sarah Baatout
Pages: 1429-1441
Published online on: 29 August 2011

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Article

Estrogen inhibits the effects of obesity and alcohol on mammary tumors and fatty liver

Jina Hong, Valerie B. Holcomb, Kyoko Kushiro, Nomelí P. Núñez
Pages: 1443-1453
Published online on: 17 August 2011

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Interferon/STAT1 and neuregulin signaling pathways are exploratory biomarkers of cetuximab (Erbitux®) efficacy in KRAS wild-type squamous carcinomas: A pathway-based analysis of whole human-genome microarray data from cetuximab-adapted tumor cell-line models

Cristina Oliveras-Ferraros, Alejandro Vazquez-Martin, Bernardo Queralt, Manuel Adrados, Rosa Ortiz, Silvia Cufí, Xavier Hernández-Yagüe, Raquel Guardeño, Luciana Báez, Begoña Martin-Castillo, Maria Carmen Pérez-Martínez, Eugeni Lopez-Bonet, Rafael De Llorens, Luis Bernadó, Joan Brunet, Javier A. Menendez
Pages: 1455-1479
Published online on: 09 August 2011

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Metastatic suppressor CD44 is related with oxidative stress in breast cancer cell lines

C. Echiburú-Chau, D. Roy, G. M. Calaf
Pages: 1481-1489
Published online on: 09 August 2011

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Upregulation of NKG2D ligands and enhanced natural killer cell cytotoxicity by hydralazine and valproate

A. Chávez-Blanco, E. De la Cruz-Hernández, G. I. Domínguez, O. Rodríguez-Cortez, B. Alatorre, E. Pérez-Cárdenas, R. Chacón-Salinas, C. Trejo-Becerril, L. Taja-Chayeb, J. E. Trujillo, A. Contreras-Paredes, A. Dueñas-González
Pages: 1491-1499
Published online on: 26 July 2011

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Involvement of EGFR in the promotion of malignant properties in multidrug resistant breast cancer cells

Jia-Wen Xu, Qing-Quan Li, Li-Li Tao, Yuan-Yuan Cheng, Juan Yu, Qi Chen, Xiu-Ping Liu, Zu-De Xu
Pages: 1501-1509
Published online on: 26 July 2011

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A murine model of hepatitis B-associated hepatocellular carcinoma generated by adeno-associated virus-mediated gene delivery

Ya-Hui Huang, Cheng-Chieh Fang, Koichi Tsuneyama, Ho-Yuan Chou, Wen-Yu Pan, Yao-Ming Shih, Ping-Yi Wu, Yin Chen, Patrick S.C. Leung, M. Eric Gershwin, Mi-Hua Tao
Pages: 1511-1519
Published online on: 28 July 2011

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Chronic administration of green tea extract to TRAMP mice induces the collapse of Golgi apparatus in prostate secretory cells and results in alterations of protein post-translational processing

Pierpaola Davalli, Federica Rizzi, Gaetano Felice Caldara, Serena Davoli, Arnaldo Corti, Alessandro Silva, Serenella Astancolle, Marco Vitale, Saverio Bettuzzi, Marialuisa Arcari, Giacomo Azzali
Pages: 1521-1527
Published online on: 20 July 2011

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Article

Anti-tumor activity of the proteasome inhibitor bortezomib in gastric cancer

Wachiko Nakata, Yoku Hayakawa, Hayato Nakagawa, Kei Sakamoto, Hiroto Kinoshita, Ryota Takahashi, Yoshihiro Hirata, Shin Maeda, Kazuhiko Koike
Pages: 1529-1536
Published online on: 22 July 2011

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Article

mTHPC-based photodynamic therapy induction of autophagy and apoptosis in cultured cells in relation to mitochondria and endoplasmic reticulum stress

Aurélie François, Sophie Marchal, François Guillemin, Lina Bezdetnaya
Pages: 1537-1543
Published online on: 24 August 2011

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Article

Inhibition of induced autophagy increases apoptosis of Nara-H cells

Osamu Nakamura, Toshiaki Hitora, Toshihiro Akisue, Teruya Kawamoto, Yoshiki Yamagami, Tetsuji Yamamoto
Pages: 1545-1552
Published online on: 29 July 2011

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Article

Levels of acute inflammatory biomarkers in advanced prostate cancer patients with α2-macroglobulin deficiency

Yuhsaku Kanoh, Hideki Ohtani, Shin Egawa, Shiro Baba, Tohru Akahoshi
Pages: 1553-1558
Published online on: 05 September 2011

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Article

Expression of LDL-A module of relaxin receptor in prostate cancer cells inhibits tumorigenesis

Shu Feng, Alexander I. Agoulnik
Pages: 1559-1565
Published online on: 12 August 2011

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Article

Pharmacological targeting of the constitutively activated MEK/MAPK-dependent signaling pathway in glioma cells inhibits cell proliferation and migration

Alexander Glassmann, Karl Reichmann, Björn Scheffler, Martin Glas, Nadine Veit, Rainer Probstmeier
Pages: 1567-1575
Published online on: 17 August 2011

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Article

Redistribution of DR4 and DR5 in lipid rafts accounts for the sensitivity to TRAIL in NSCLC cells

Wen Ouyang, Chunxu Yang, Yu Liu, Jie Xiong, Junhong Zhang, Yahua Zhong, Gong Zhang, Fuxiang Zhou, Yunfeng Zhou, Conghua Xie
Pages: 1577-1586
Published online on: 18 July 2011

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Article

Deciphering the role of paclitaxel in the SKGT4 human esophageal adenocarcinoma cell line

Seo Ju Kim, Myoung Ja Chung, Jong-Suk Kim, Bumseok Kim, Woo Hyun Park, Suhn Hee Kim, Sung Zoo Kim, Ju-Seog Lee, Soo Mi Kim
Pages: 1587-1591
Published online on: 20 July 2011

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Article

Simvastatin reduces tumor cell adhesion to human peritoneal mesothelial cells by decreased expression of VCAM-1 and β1 integrin

Britta Janina Wagner, Stefan  Löb, Dennis  Lindau, Helen Hörzer, Brigitte Gückel, Gerd Klein, Jörg Glatzle, Hans-Georg  Rammensee, Björn Lucas Brücher, Alfred  Königsrainer
Pages: 1593-1600
Published online on: 18 August 2011

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Article

Clonal cytogenetic progression within intratumorally heterogeneous meningiomas predicts tumor recurrence

Steffi Urbschat, Jörg Rahnenführer, Wolfram Henn, Wolfgang Feiden, Silke Wemmert, Stefan Linsler, Klaus D. Zang, Joachim Oertel, Ralf Ketter
Pages: 1601-1608
Published online on: 12 September 2011

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Article

A novel cromakalim analogue induces cell cycle arrest and apoptosis in human cervical carcinoma HeLa cells through the caspase- and mitochondria-dependent pathway

Xin Zhang, Jing Zhao, Saeromi Kang, Myeongjin Yi, Song You, Dong-Soo Shin, Dong-Kyoo Kim
Pages: 1609-1617
Published online on: 09 August 2011

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Article

Decreased accumulation of immune regulatory cells is correlated to the antitumor effect of IFN-γ overexpression in the tumor

Roberto Carrio, Marta Torroella-Kouri, Stephania Libreros, Ramón A. García-Areas, Vijaya Iragavarapu-Charyulu, Diana M. López
Pages: 1619-1627
Published online on: 18 August 2011

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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Article Open Access

lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Review Open Access

Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Review Open Access

Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Review Open Access

Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Review Open Access

Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Review Open Access

Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma

Nawal Merjaneh, Ying-Wei Lan, Zicheng Deng, Johnny Donovan, Guolun Wang, Jonathan Do, Tiffany Juan, Xiaomei Xia, Vladimir V. Kalinichenko, Tanya V. Kalin
Article Number: 52
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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Article Open Access

RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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