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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2011 Volume 39 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Oligodendroglioma cells shed microvesicles which contain TRAIL as well as molecular chaperones and induce cell death in astrocytes

Alessandra Lo Cicero, Gabriella Schiera, Patrizia Proia, Patrizia Saladino, Giovanni Savettieri, Carlo Maria Di Liegro, Italia Di Liegro
Pages: 1353-1357
Published online on: 12 August 2011

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Article

The potent peptide antagonist to angiogenesis, C16Y, and cisplatin act synergistically in the down-regulation of the Bcl-2/Bax ratio and the induction of apoptosis in human ovarian cancer cells

Akiko Shinagawa, Yoshio Yoshida, Tetsuji Kurokawa, Yuko Horiuchi, Hideaki Tsuyoshi, Makoto Orisaka, Yoko Sawamura, Hynda K. Kleinman, Fumikazu Kotsuji
Pages: 1359-1364
Published online on: 20 July 2011

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Article

Frequent deletion of 3p21.1 region carrying semaphorin 3G and aberrant expression of the genes participating in semaphorin signaling in the epithelioid type of malignant mesothelioma cells

Yoshie Yoshikawa, Ayuko Sato, Tohru Tsujimura, Tomonori Morinaga, Kazuya Fukuoka, Shusai Yamada, Aki Murakami, Nobuyuki Kondo, Seiji Matsumoto, Yoshitomo Okumura, Fumihiro Tanaka, Seiki Hasegawa, Tomoko Hashimoto-Tamaoki, Takashi Nakano
Pages: 1365-1374
Published online on: 12 August 2011

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Article

Ultra-violet irradiation induces apoptosis via mitochondrial pathway in pancreatic cancer cells

Takahiro Yamauchi, Seiji Adachi, Ichiro Yasuda, Masanori Nakashima, Junji Kawaguchi, Takashi Yoshioka, Yoshinobu Hirose, Osamu Kozawa, Hisataka Moriwaki
Pages: 1375-1380
Published online on: 05 September 2011

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Article

Antitumor and apoptosis-promoting properties of emodin, an anthraquinone derivative from Rheum officinale Baill, against pancreatic cancer in mice via inhibition of Akt activation

Wei-Τian Wei, Hui Chen, Zhong-Lin Ni, Hai-Βin Liu, Hong-Fei Tong, Ling Fan, An Liu, Mai-Χuan Qiu, Dian-Lei Liu, Hong-Chun Guo, Zhao-Hong Wang, Sheng-Zhang Lin
Pages: 1381-1390
Published online on: 29 July 2011

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Article

Increased ΔNp63 expression is predictive of malignant transformation in oral epithelial dysplasia and poor prognosis in oral squamous cell carcinoma

Ryota Matsubara, Shintaro Kawano, Takahiro Kiyosue, Yuichi Goto, Mitsuhiro Hirano, Teppei Jinno, Takeshi Toyoshima, Ryoji Kitamura, Kazunari Oobu, Seiji Nakamura
Pages: 1391-1399
Published online on: 09 August 2011

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Article

A novel function of EpCAM in oral squamous cell carcinoma cells under anchorage-independent conditions

Hiroshi Inoue, Yuichi Ohnishi, Masahiro Nakajima, Kenji Kakudo, Masami Nozaki
Pages: 1401-1405
Published online on: 22 July 2011

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Article

Regional therapy with DTA-H19 vector suppresses growth of colon adenocarcinoma metastases in the rat liver

Vladimir Sorin, Patricia Ohana, Aya Mizrahi, Imad Matouk, Tatiana Birman, Abraham Hochberg, Abraham Czerniak
Pages: 1407-1412
Published online on: 18 August 2011

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Article

Prognostic impact of p53 aberrations for R-CHOP-treated patients with diffuse large B-cell lymphoma

Lenka Stefancikova, Mojmir Moulis, Pavel Fabian, Ingrid Vasova, Frantisek Zedek, Barbora Ravcukova, Jan Muzik, Petr Kuglik, Vladimira Vranova, Iva Falkova, Renata Hrabalkova, Jana Smardova
Pages: 1413-1420
Published online on: 18 August 2011

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Article

Chondroitin sulfate expression predicts poor outcome in breast cancer

Katrin J. Svensson, Helena C. Christianson, Paulina Kucharzewska, Victor Fagerström, Lars Lundstedt, Signe Borgquist, Karin Jirström, Mattias Belting
Pages: 1421-1428
Published online on: 17 August 2011

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Article

Response to low-dose X-irradiation is p53-dependent in a papillary thyroid carcinoma model system

Khalil Abou-El-Ardat, Hanane Derradji, Winnok de Vos, Tim de Meyer, Sofie Bekaert, Wim van Criekinge, Sarah Baatout
Pages: 1429-1441
Published online on: 29 August 2011

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Article

Estrogen inhibits the effects of obesity and alcohol on mammary tumors and fatty liver

Jina Hong, Valerie B. Holcomb, Kyoko Kushiro, Nomelí P. Núñez
Pages: 1443-1453
Published online on: 17 August 2011

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Interferon/STAT1 and neuregulin signaling pathways are exploratory biomarkers of cetuximab (Erbitux®) efficacy in KRAS wild-type squamous carcinomas: A pathway-based analysis of whole human-genome microarray data from cetuximab-adapted tumor cell-line models

Cristina Oliveras-Ferraros, Alejandro Vazquez-Martin, Bernardo Queralt, Manuel Adrados, Rosa Ortiz, Silvia Cufí, Xavier Hernández-Yagüe, Raquel Guardeño, Luciana Báez, Begoña Martin-Castillo, Maria Carmen Pérez-Martínez, Eugeni Lopez-Bonet, Rafael De Llorens, Luis Bernadó, Joan Brunet, Javier A. Menendez
Pages: 1455-1479
Published online on: 09 August 2011

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Article

Metastatic suppressor CD44 is related with oxidative stress in breast cancer cell lines

C. Echiburú-Chau, D. Roy, G. M. Calaf
Pages: 1481-1489
Published online on: 09 August 2011

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Article

Upregulation of NKG2D ligands and enhanced natural killer cell cytotoxicity by hydralazine and valproate

A. Chávez-Blanco, E. De la Cruz-Hernández, G. I. Domínguez, O. Rodríguez-Cortez, B. Alatorre, E. Pérez-Cárdenas, R. Chacón-Salinas, C. Trejo-Becerril, L. Taja-Chayeb, J. E. Trujillo, A. Contreras-Paredes, A. Dueñas-González
Pages: 1491-1499
Published online on: 26 July 2011

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Article

Involvement of EGFR in the promotion of malignant properties in multidrug resistant breast cancer cells

Jia-Wen Xu, Qing-Quan Li, Li-Li Tao, Yuan-Yuan Cheng, Juan Yu, Qi Chen, Xiu-Ping Liu, Zu-De Xu
Pages: 1501-1509
Published online on: 26 July 2011

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Article

A murine model of hepatitis B-associated hepatocellular carcinoma generated by adeno-associated virus-mediated gene delivery

Ya-Hui Huang, Cheng-Chieh Fang, Koichi Tsuneyama, Ho-Yuan Chou, Wen-Yu Pan, Yao-Ming Shih, Ping-Yi Wu, Yin Chen, Patrick S.C. Leung, M. Eric Gershwin, Mi-Hua Tao
Pages: 1511-1519
Published online on: 28 July 2011

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Article

Chronic administration of green tea extract to TRAMP mice induces the collapse of Golgi apparatus in prostate secretory cells and results in alterations of protein post-translational processing

Pierpaola Davalli, Federica Rizzi, Gaetano Felice Caldara, Serena Davoli, Arnaldo Corti, Alessandro Silva, Serenella Astancolle, Marco Vitale, Saverio Bettuzzi, Marialuisa Arcari, Giacomo Azzali
Pages: 1521-1527
Published online on: 20 July 2011

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Article

Anti-tumor activity of the proteasome inhibitor bortezomib in gastric cancer

Wachiko Nakata, Yoku Hayakawa, Hayato Nakagawa, Kei Sakamoto, Hiroto Kinoshita, Ryota Takahashi, Yoshihiro Hirata, Shin Maeda, Kazuhiko Koike
Pages: 1529-1536
Published online on: 22 July 2011

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Article

mTHPC-based photodynamic therapy induction of autophagy and apoptosis in cultured cells in relation to mitochondria and endoplasmic reticulum stress

Aurélie François, Sophie Marchal, François Guillemin, Lina Bezdetnaya
Pages: 1537-1543
Published online on: 24 August 2011

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Article

Inhibition of induced autophagy increases apoptosis of Nara-H cells

Osamu Nakamura, Toshiaki Hitora, Toshihiro Akisue, Teruya Kawamoto, Yoshiki Yamagami, Tetsuji Yamamoto
Pages: 1545-1552
Published online on: 29 July 2011

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Article

Levels of acute inflammatory biomarkers in advanced prostate cancer patients with α2-macroglobulin deficiency

Yuhsaku Kanoh, Hideki Ohtani, Shin Egawa, Shiro Baba, Tohru Akahoshi
Pages: 1553-1558
Published online on: 05 September 2011

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Article

Expression of LDL-A module of relaxin receptor in prostate cancer cells inhibits tumorigenesis

Shu Feng, Alexander I. Agoulnik
Pages: 1559-1565
Published online on: 12 August 2011

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Article

Pharmacological targeting of the constitutively activated MEK/MAPK-dependent signaling pathway in glioma cells inhibits cell proliferation and migration

Alexander Glassmann, Karl Reichmann, Björn Scheffler, Martin Glas, Nadine Veit, Rainer Probstmeier
Pages: 1567-1575
Published online on: 17 August 2011

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Article

Redistribution of DR4 and DR5 in lipid rafts accounts for the sensitivity to TRAIL in NSCLC cells

Wen Ouyang, Chunxu Yang, Yu Liu, Jie Xiong, Junhong Zhang, Yahua Zhong, Gong Zhang, Fuxiang Zhou, Yunfeng Zhou, Conghua Xie
Pages: 1577-1586
Published online on: 18 July 2011

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Article

Deciphering the role of paclitaxel in the SKGT4 human esophageal adenocarcinoma cell line

Seo Ju Kim, Myoung Ja Chung, Jong-Suk Kim, Bumseok Kim, Woo Hyun Park, Suhn Hee Kim, Sung Zoo Kim, Ju-Seog Lee, Soo Mi Kim
Pages: 1587-1591
Published online on: 20 July 2011

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Article

Simvastatin reduces tumor cell adhesion to human peritoneal mesothelial cells by decreased expression of VCAM-1 and β1 integrin

Britta Janina Wagner, Stefan  Löb, Dennis  Lindau, Helen Hörzer, Brigitte Gückel, Gerd Klein, Jörg Glatzle, Hans-Georg  Rammensee, Björn Lucas Brücher, Alfred  Königsrainer
Pages: 1593-1600
Published online on: 18 August 2011

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Article

Clonal cytogenetic progression within intratumorally heterogeneous meningiomas predicts tumor recurrence

Steffi Urbschat, Jörg Rahnenführer, Wolfram Henn, Wolfgang Feiden, Silke Wemmert, Stefan Linsler, Klaus D. Zang, Joachim Oertel, Ralf Ketter
Pages: 1601-1608
Published online on: 12 September 2011

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Article

A novel cromakalim analogue induces cell cycle arrest and apoptosis in human cervical carcinoma HeLa cells through the caspase- and mitochondria-dependent pathway

Xin Zhang, Jing Zhao, Saeromi Kang, Myeongjin Yi, Song You, Dong-Soo Shin, Dong-Kyoo Kim
Pages: 1609-1617
Published online on: 09 August 2011

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Article

Decreased accumulation of immune regulatory cells is correlated to the antitumor effect of IFN-γ overexpression in the tumor

Roberto Carrio, Marta Torroella-Kouri, Stephania Libreros, Ramón A. García-Areas, Vijaya Iragavarapu-Charyulu, Diana M. López
Pages: 1619-1627
Published online on: 18 August 2011

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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