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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2011 Volume 39 Issue 6

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Oligodendroglioma cells shed microvesicles which contain TRAIL as well as molecular chaperones and induce cell death in astrocytes

Alessandra Lo Cicero, Gabriella Schiera, Patrizia Proia, Patrizia Saladino, Giovanni Savettieri, Carlo Maria Di Liegro, Italia Di Liegro
Pages: 1353-1357
Published online on: 12 August 2011

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Article

The potent peptide antagonist to angiogenesis, C16Y, and cisplatin act synergistically in the down-regulation of the Bcl-2/Bax ratio and the induction of apoptosis in human ovarian cancer cells

Akiko Shinagawa, Yoshio Yoshida, Tetsuji Kurokawa, Yuko Horiuchi, Hideaki Tsuyoshi, Makoto Orisaka, Yoko Sawamura, Hynda K. Kleinman, Fumikazu Kotsuji
Pages: 1359-1364
Published online on: 20 July 2011

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Article

Frequent deletion of 3p21.1 region carrying semaphorin 3G and aberrant expression of the genes participating in semaphorin signaling in the epithelioid type of malignant mesothelioma cells

Yoshie Yoshikawa, Ayuko Sato, Tohru Tsujimura, Tomonori Morinaga, Kazuya Fukuoka, Shusai Yamada, Aki Murakami, Nobuyuki Kondo, Seiji Matsumoto, Yoshitomo Okumura, Fumihiro Tanaka, Seiki Hasegawa, Tomoko Hashimoto-Tamaoki, Takashi Nakano
Pages: 1365-1374
Published online on: 12 August 2011

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Article

Ultra-violet irradiation induces apoptosis via mitochondrial pathway in pancreatic cancer cells

Takahiro Yamauchi, Seiji Adachi, Ichiro Yasuda, Masanori Nakashima, Junji Kawaguchi, Takashi Yoshioka, Yoshinobu Hirose, Osamu Kozawa, Hisataka Moriwaki
Pages: 1375-1380
Published online on: 05 September 2011

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Article

Antitumor and apoptosis-promoting properties of emodin, an anthraquinone derivative from Rheum officinale Baill, against pancreatic cancer in mice via inhibition of Akt activation

Wei-Τian Wei, Hui Chen, Zhong-Lin Ni, Hai-Βin Liu, Hong-Fei Tong, Ling Fan, An Liu, Mai-Χuan Qiu, Dian-Lei Liu, Hong-Chun Guo, Zhao-Hong Wang, Sheng-Zhang Lin
Pages: 1381-1390
Published online on: 29 July 2011

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Article

Increased ΔNp63 expression is predictive of malignant transformation in oral epithelial dysplasia and poor prognosis in oral squamous cell carcinoma

Ryota Matsubara, Shintaro Kawano, Takahiro Kiyosue, Yuichi Goto, Mitsuhiro Hirano, Teppei Jinno, Takeshi Toyoshima, Ryoji Kitamura, Kazunari Oobu, Seiji Nakamura
Pages: 1391-1399
Published online on: 09 August 2011

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Article

A novel function of EpCAM in oral squamous cell carcinoma cells under anchorage-independent conditions

Hiroshi Inoue, Yuichi Ohnishi, Masahiro Nakajima, Kenji Kakudo, Masami Nozaki
Pages: 1401-1405
Published online on: 22 July 2011

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Article

Regional therapy with DTA-H19 vector suppresses growth of colon adenocarcinoma metastases in the rat liver

Vladimir Sorin, Patricia Ohana, Aya Mizrahi, Imad Matouk, Tatiana Birman, Abraham Hochberg, Abraham Czerniak
Pages: 1407-1412
Published online on: 18 August 2011

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Article

Prognostic impact of p53 aberrations for R-CHOP-treated patients with diffuse large B-cell lymphoma

Lenka Stefancikova, Mojmir Moulis, Pavel Fabian, Ingrid Vasova, Frantisek Zedek, Barbora Ravcukova, Jan Muzik, Petr Kuglik, Vladimira Vranova, Iva Falkova, Renata Hrabalkova, Jana Smardova
Pages: 1413-1420
Published online on: 18 August 2011

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Article

Chondroitin sulfate expression predicts poor outcome in breast cancer

Katrin J. Svensson, Helena C. Christianson, Paulina Kucharzewska, Victor Fagerström, Lars Lundstedt, Signe Borgquist, Karin Jirström, Mattias Belting
Pages: 1421-1428
Published online on: 17 August 2011

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Article

Response to low-dose X-irradiation is p53-dependent in a papillary thyroid carcinoma model system

Khalil Abou-El-Ardat, Hanane Derradji, Winnok de Vos, Tim de Meyer, Sofie Bekaert, Wim van Criekinge, Sarah Baatout
Pages: 1429-1441
Published online on: 29 August 2011

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Article

Estrogen inhibits the effects of obesity and alcohol on mammary tumors and fatty liver

Jina Hong, Valerie B. Holcomb, Kyoko Kushiro, Nomelí P. Núñez
Pages: 1443-1453
Published online on: 17 August 2011

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Article

Interferon/STAT1 and neuregulin signaling pathways are exploratory biomarkers of cetuximab (Erbitux®) efficacy in KRAS wild-type squamous carcinomas: A pathway-based analysis of whole human-genome microarray data from cetuximab-adapted tumor cell-line models

Cristina Oliveras-Ferraros, Alejandro Vazquez-Martin, Bernardo Queralt, Manuel Adrados, Rosa Ortiz, Silvia Cufí, Xavier Hernández-Yagüe, Raquel Guardeño, Luciana Báez, Begoña Martin-Castillo, Maria Carmen Pérez-Martínez, Eugeni Lopez-Bonet, Rafael De Llorens, Luis Bernadó, Joan Brunet, Javier A. Menendez
Pages: 1455-1479
Published online on: 09 August 2011

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Article

Metastatic suppressor CD44 is related with oxidative stress in breast cancer cell lines

C. Echiburú-Chau, D. Roy, G. M. Calaf
Pages: 1481-1489
Published online on: 09 August 2011

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Article

Upregulation of NKG2D ligands and enhanced natural killer cell cytotoxicity by hydralazine and valproate

A. Chávez-Blanco, E. De la Cruz-Hernández, G. I. Domínguez, O. Rodríguez-Cortez, B. Alatorre, E. Pérez-Cárdenas, R. Chacón-Salinas, C. Trejo-Becerril, L. Taja-Chayeb, J. E. Trujillo, A. Contreras-Paredes, A. Dueñas-González
Pages: 1491-1499
Published online on: 26 July 2011

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Article

Involvement of EGFR in the promotion of malignant properties in multidrug resistant breast cancer cells

Jia-Wen Xu, Qing-Quan Li, Li-Li Tao, Yuan-Yuan Cheng, Juan Yu, Qi Chen, Xiu-Ping Liu, Zu-De Xu
Pages: 1501-1509
Published online on: 26 July 2011

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Article

A murine model of hepatitis B-associated hepatocellular carcinoma generated by adeno-associated virus-mediated gene delivery

Ya-Hui Huang, Cheng-Chieh Fang, Koichi Tsuneyama, Ho-Yuan Chou, Wen-Yu Pan, Yao-Ming Shih, Ping-Yi Wu, Yin Chen, Patrick S.C. Leung, M. Eric Gershwin, Mi-Hua Tao
Pages: 1511-1519
Published online on: 28 July 2011

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Article

Chronic administration of green tea extract to TRAMP mice induces the collapse of Golgi apparatus in prostate secretory cells and results in alterations of protein post-translational processing

Pierpaola Davalli, Federica Rizzi, Gaetano Felice Caldara, Serena Davoli, Arnaldo Corti, Alessandro Silva, Serenella Astancolle, Marco Vitale, Saverio Bettuzzi, Marialuisa Arcari, Giacomo Azzali
Pages: 1521-1527
Published online on: 20 July 2011

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Article

Anti-tumor activity of the proteasome inhibitor bortezomib in gastric cancer

Wachiko Nakata, Yoku Hayakawa, Hayato Nakagawa, Kei Sakamoto, Hiroto Kinoshita, Ryota Takahashi, Yoshihiro Hirata, Shin Maeda, Kazuhiko Koike
Pages: 1529-1536
Published online on: 22 July 2011

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Article

mTHPC-based photodynamic therapy induction of autophagy and apoptosis in cultured cells in relation to mitochondria and endoplasmic reticulum stress

Aurélie François, Sophie Marchal, François Guillemin, Lina Bezdetnaya
Pages: 1537-1543
Published online on: 24 August 2011

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Article

Inhibition of induced autophagy increases apoptosis of Nara-H cells

Osamu Nakamura, Toshiaki Hitora, Toshihiro Akisue, Teruya Kawamoto, Yoshiki Yamagami, Tetsuji Yamamoto
Pages: 1545-1552
Published online on: 29 July 2011

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Article

Levels of acute inflammatory biomarkers in advanced prostate cancer patients with α2-macroglobulin deficiency

Yuhsaku Kanoh, Hideki Ohtani, Shin Egawa, Shiro Baba, Tohru Akahoshi
Pages: 1553-1558
Published online on: 05 September 2011

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Article

Expression of LDL-A module of relaxin receptor in prostate cancer cells inhibits tumorigenesis

Shu Feng, Alexander I. Agoulnik
Pages: 1559-1565
Published online on: 12 August 2011

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Article

Pharmacological targeting of the constitutively activated MEK/MAPK-dependent signaling pathway in glioma cells inhibits cell proliferation and migration

Alexander Glassmann, Karl Reichmann, Björn Scheffler, Martin Glas, Nadine Veit, Rainer Probstmeier
Pages: 1567-1575
Published online on: 17 August 2011

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Article

Redistribution of DR4 and DR5 in lipid rafts accounts for the sensitivity to TRAIL in NSCLC cells

Wen Ouyang, Chunxu Yang, Yu Liu, Jie Xiong, Junhong Zhang, Yahua Zhong, Gong Zhang, Fuxiang Zhou, Yunfeng Zhou, Conghua Xie
Pages: 1577-1586
Published online on: 18 July 2011

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Article

Deciphering the role of paclitaxel in the SKGT4 human esophageal adenocarcinoma cell line

Seo Ju Kim, Myoung Ja Chung, Jong-Suk Kim, Bumseok Kim, Woo Hyun Park, Suhn Hee Kim, Sung Zoo Kim, Ju-Seog Lee, Soo Mi Kim
Pages: 1587-1591
Published online on: 20 July 2011

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Article

Simvastatin reduces tumor cell adhesion to human peritoneal mesothelial cells by decreased expression of VCAM-1 and β1 integrin

Britta Janina Wagner, Stefan  Löb, Dennis  Lindau, Helen Hörzer, Brigitte Gückel, Gerd Klein, Jörg Glatzle, Hans-Georg  Rammensee, Björn Lucas Brücher, Alfred  Königsrainer
Pages: 1593-1600
Published online on: 18 August 2011

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Article

Clonal cytogenetic progression within intratumorally heterogeneous meningiomas predicts tumor recurrence

Steffi Urbschat, Jörg Rahnenführer, Wolfram Henn, Wolfgang Feiden, Silke Wemmert, Stefan Linsler, Klaus D. Zang, Joachim Oertel, Ralf Ketter
Pages: 1601-1608
Published online on: 12 September 2011

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Article

A novel cromakalim analogue induces cell cycle arrest and apoptosis in human cervical carcinoma HeLa cells through the caspase- and mitochondria-dependent pathway

Xin Zhang, Jing Zhao, Saeromi Kang, Myeongjin Yi, Song You, Dong-Soo Shin, Dong-Kyoo Kim
Pages: 1609-1617
Published online on: 09 August 2011

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Article

Decreased accumulation of immune regulatory cells is correlated to the antitumor effect of IFN-γ overexpression in the tumor

Roberto Carrio, Marta Torroella-Kouri, Stephania Libreros, Ramón A. García-Areas, Vijaya Iragavarapu-Charyulu, Diana M. López
Pages: 1619-1627
Published online on: 18 August 2011

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Journal Cover
October-2026 Volume 69 Issue 4

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

MicroRNA regulation of macrophage polarization in lung cancer: Regulatory networks and therapeutic potential (Review)

Zhao Yiming, Li Jie
Article Number: 121
Published online on: 02 September 2026

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Article Open Access

Effect of xeroderma pigmentosum group C on the characteristics and regulatory mechanisms of lung cancer stem cells

Ben Yang, Yang Yang, Weiyu Wang, Yubing Wang, Huaijie Wang, Liya Qin, Yongming Wang, Sipeng Sun, Shubo Wang, Meihua Qu
Article Number: 120
Published online on: 01 September 2026

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Review Open Access

Post‑translational modification‑governed immune states in cancer immunity: Biomarker implications for checkpoint competence, tumor visibility and immunotherapy resistance (Review)

Jinghao Pan, Boyang Li, Ruonan Lin, Chenlu Fang, Lucy Yue Lau, Zehao Hong, Yi Chen
Article Number: 119
Published online on: 21 August 2026

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Correction Open Access

[Corrigendum] Sulforaphane reduces molecular response to hypoxia in ovarian tumor cells independently of their resistance to chemotherapy

Michal Pastorek, Veronika Simko, Martina Takacova, Monika Barathova, Maria Bartosova, Luba Hunakova, Olga Sedlakova, Sona Hudecova, Olga Krizanova, Franck Dequiedt, Silvia Pastorekova, Jan Sedlak
Article Number: 118
Published online on: 20 August 2026

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Article Open Access

Single in situ intratumoral low‑dose shikonin hydrogel plus mild photothermal therapy elicits systemic antitumor immunity in immune‑cold triple‑negative breast cancer

Tao Pan, Zujian Feng, Ting Shang, Jun Jiang, Fang Zhang
Article Number: 117
Published online on: 19 August 2026

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Article Open Access

KIAA1429 knockdown alleviates osteosarcoma  progression by destabilizing SLC7A11 mRNA via m6A methylation to promote ferroptosis

Hui Zeng, Yunyan Zhong, Dingbiao Zeng, Shiliang Xiao, Song Zou
Article Number: 116
Published online on: 17 August 2026

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Correction Open Access

[Corrigendum] Tanshinone I effectively induces apoptosis in estrogen receptor‑positive (MCF‑7) and estrogen receptor‑negative (MDA‑MB‑231) breast cancer cells

Irina Tsoy Nizamutdinova, Gyeong Won Lee, Kun Ho Son, Su Jin Jeon, Sam Sik Kang, Yeong Shik Kim, Jae Heun Lee, Han Geuk Seo, Ki Churl Chang, Hye Jung Kim
Article Number: 115
Published online on: 12 August 2026

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Review Open Access

Signaling pathways and targeted therapy in high‑risk refractory thyroid cancer: From bench to bedside (Review)

Jian Wang, Zhi Liu, Qing Zhang, Wei Sun
Article Number: 114
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Downmodulation of dimethyl transferase activity enhances tumor necrosis factor‑related apoptosis‑inducing ligand‑ induced apoptosis in prostate cancer cells

Claudio Festuccia, Giovanni Luca Gravina, Anna Maria D'Alessandro, Danilo Millimaggi, Cristiana Di Rocco, Vincenza Dolo, Enrico Ricevuto, Carlo Vicentini, Mauro Bologna
Article Number: 113
Published online on: 10 August 2026

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Review Open Access

The pivotal role of SCD1 in digestive cancers: Bridging lipid metabolic reprogramming and programmed cell death (Review)

Yangxi Fu, Zheng Wang, Lin Liu, Xudong Tang
Article Number: 112
Published online on: 07 August 2026

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Article Open Access

piR‑164552 promotes malignant progression in head and neck squamous cell carcinoma via the RBM4/EIF4E2 signaling axis: Insights from multi‑omics and functional analyses

Shan Yang, Zhen Shang, Shunxian Xia, Hongbo Liu, Yanhan Dong, Xiaomin Wang, Wenhua Xu, Haijun Lu
Article Number: 111
Published online on: 07 August 2026

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Correction Open Access

[Corrigendum] Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines

Nesstor Pilco‑Ferreto, Gloria   M. Calaf
Article Number: 110
Published online on: 20 July 2026

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Article Open Access

Evaluation of Punicalagin as a multi‑targeted therapeutic agent against endometrial cancer

Zeeshan Ahmad Bhutta, Dohee Ahn, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 109
Published online on: 17 July 2026

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Journal Cover
November-2026 Volume 69 Issue 5

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] In vitro modulation of MMP‑2 and MMP‑9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors

M.W. Roomi, T. Kalinovsky, J.  Monterrey, M. Rath, A. Niedzwiecki
Article Number: 129
Published online on: 21 September 2026

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Review Open Access

Eomesodermin in renal cell carcinoma: Epigenetic and immune crosstalk driving tumor progression (Review)

Zhifei Che, Dongwen Huang, Jiaming Lin, Xincen Wang, Rongjin Feng, Xianping Che, Yubin Wang
Article Number: 128
Published online on: 18 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ultraviolet exposure of melanoma cells induces fibroblast activation protein‑α in fibroblasts: Implications for melanoma invasion

Petra Wäster, Inger Rosdahl, Brendan F.  Gilmore, Oliver Seifert
Article Number: 127
Published online on: 16 September 2026

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Article Open Access

E3 ubiquitin ligase MAGI3‑mediated TAZ ubiquitination suppresses the non‑small cell lung cancer occurrence and development by targeting the Wnt pathway

Ye Liang, Jie Zhuang
Article Number: 126
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] TIP60 governs the auto‑ubiquitination of UHRF1 through USP7 dissociation from the UHRF1/USP7 complex

Tanveer Ahmad, Waseem Ashraf, Abdulkhaleg Ibrahim, Liliyana Zaayter, Christian D. Muller, Ali Hamiche, Yves Mély, Christian Bronner, Marc Mousli
Article Number: 125
Published online on: 14 September 2026

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Correction Open Access

[Corrigendum] miR‑221/222 promote malignant progression of glioma through activation of the Akt pathway

Junxia Zhang, Lei Han, Youlin Ge, Xuan Zhou, Anling Zhang, Chunzhi Zhang, Yue Zhong, Yongping You, Peiyu Pu, Chunsheng Kang
Article Number: 124
Published online on: 03 September 2026

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Review Open Access

Dendritic cell‑based vaccines for colorectal cancer: Mechanisms, clinical progress and future directions (Review)

Lian Yih Pong, Siti Ayuni Hassanudin, Seng Kong Tham, Ravichandran Manickam, Chee Yin Wong, Keat Seong Poh, Chit Laa Poh
Article Number: 123
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Pro‑metastatic intracellular signaling of the elaidic trans fatty acid

Kiyomu Fujii, Yi Luo, Rina Fujiwara-tani, Shingo Kishi, Song He, Shuyun Yang, Takamitsu Sasaki, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 122
Published online on: 02 September 2026

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