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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2006 Volume 16 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Cystatins in non-small cell lung cancer: Tissue levels, localization and relation to prognosis

Bernd Werle, Ulrike Schanzenbächer, Tamara Turensek Lah, Eileen Ebert, Britta Jülke, Werner Ebert, Werner Fiehn, Klaus Kayser, Eberhard Spiess, Magnus Abrahamson, Janko Kos
Pages: 647-655
Published online on: 01 October 2006

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Article

Expression of the mutated transketolase TKTL1, a molecular marker in gastric cancer

Wilko I. Staiger, Johannes F. Coy, Rainer Grobholz, Ralf-Dieter Hofheinz, Nadine Lukan, Stefan Post, Matthias H. Schwarzbach, Frank Willeke
Pages: 657-661
Published online on: 01 October 2006

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Article

Differential expression in histologically normal crypts of ulcerative colitis suggests primary crypt disorder

Mijung Kim, Seungkoo Lee, Suk-Kyun Yang, Kyuyoung Song, Inchul Lee
Pages: 663-670
Published online on: 01 October 2006

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Article

The role of S100A1 in external auditory canal cholesteatoma

Ramin Naim, Karl Hormann
Pages: 671-675
Published online on: 01 October 2006

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Article

Assessment of the severity of liver disease and fibrotic change: The usefulness of hepatic CT perfusion imaging

Kazuhiko Hashimoto, Takamichi Murakami, Keizo Dono, Masatoshi Hori, Tonsok Kim, Masayuki Kudo, Shigeru Marubashi, Atsushi Miyamoto, Yutaka Takeda, Hiroaki Nagano, Koji Umeshita, Hironobu Nakamura, Morito Monden
Pages: 677-683
Published online on: 01 October 2006

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Article

Genetic progression and divergence in superficial esophageal squamous cell carcinoma by loss of heterozygosity analysis

Hideyuki Shima, Toru Hiyama, Shinji Tanaka, Masaharu Yoshihara, Koji Arihiro, Kazuaki Chayama
Pages: 685-691
Published online on: 01 October 2006

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Article

Vasculogenic mimicry is associated with high tumor grade, invasion and metastasis, and short survival in patients with hepatocellular carcinoma

Baocun Sun, Shiwu Zhang, Danfang Zhang, Jing Du, Hua Guo, Xiulan Zhao, Wei Zhang, Xishan Hao
Pages: 693-698
Published online on: 01 October 2006

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Article

The S1P receptor modulator FTY720 prevents the development of experimental colitis in mice

Yasuyuki Deguchi, Akira Andoh, Yuki Yagi, Shigeki Bamba, Osamu Inatomi, Tomoyuki Tsujikawa, Yoshihide Fujiyama
Pages: 699-703
Published online on: 01 October 2006

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Article

Proteomic analysis of a highly metastatic gastric cancer cell line using two-dimensional differential gel electrophoresis

Masako Takikawa, Yasuto Akiyama, Kouji Maruyama, Ayako Suzuki, Feng Liu, Sachiko Tai, Chie Ohshita, Yoshihiro Kawaguchi, Etsurou Bandou, Yutaka Yonemura, Ken Yamaguchi
Pages: 705-711
Published online on: 01 October 2006

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Article

Inhibition of murine K-BALB and CT26 tumour growth using a Semliki Forest virus vector with enhanced expression of IL-18

C. P. Chikkanna-Gowda, S. McNally, B. J. Sheahan, M. N. Fleeton, G. J. Atkins
Pages: 713-719
Published online on: 01 October 2006

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Article

Expression of chemoresistance-related proteins in α-fetoprotein-producing adenocarcinoma of the digestive organs

Shingo Kamoshida, Mai Suzuki, Yoichi Sakurai, Masahiro Ochiai, Fumikazu Kimura, Sadahito Kuwao, Kazuki Sakamoto, Yoshikazu Sugimoto, Masakazu Fukushima, Yutaka Tsutsumi
Pages: 721-727
Published online on: 01 October 2006

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Article

Differential expression of claudin-4 between intestinal and diffuse-type gastric cancer

Wen-Ling Kuo, Li-Yu Lee, Chi-Ming Wu, Chee-Chan Wang, Jau-Song Yu, Ying Liang, Chih-Hong Lo, Kuo-Hao Huang, Tsann-Long Hwang
Pages: 729-734
Published online on: 01 October 2006

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Article

Characteristic features of disseminated carcinomatosis of the bone marrow due to gastric cancer: The pathogenesis of bone destruction

Hiroki Kusumoto, Masaru Haraguchi, Yoko Nozuka, Yoshinao Oda, Masazumi Tsuneyoshi, Haruo Iguchi
Pages: 735-740
Published online on: 01 October 2006

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Article

Comparison of CD44 expression in primary tumours and metastases of colorectal cancer

R. Bendardaf, A. Algars, A. Elzagheid, E. Korkeila, R. Ristamäki, H. Lamlum, Y. Collan, K. Syrjänen, S. Pyrhönen
Pages: 741-746
Published online on: 01 October 2006

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Article

Differential expression in normal-adenoma-carcinoma sequence suggests complex molecular carcinogenesis in colon

Seungkoo Lee, Seunghyun Bang, Kyuyoung Song, Inchul Lee
Pages: 747-754
Published online on: 01 October 2006

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Article

AKAPs competing peptide HT31 disrupts the inhibitory effect of PKA on RhoA activity

Ying Wang, Yongchang Chen, Min Chen, Wenrong Xu
Pages: 755-761
Published online on: 01 October 2006

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Article

99mTc-tetrofosmin SPECT in solitary pulmonary nodule evaluation

Angela Spanu, Orazio Schillaci, Pietro Pirina, Antonio Arru, Giordano Madeddu, Francesca Chessa, Pietro Marongiu, Maria Elisabetta Solinas, Giuseppe Madeddu
Pages: 763-769
Published online on: 01 October 2006

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Article

Cyclooxygenase-2 inhibitor, nimesulide, improves radiation treatment against non-small cell lung cancer both in vitro and in vivo

Kristopher R. Grimes, Graham W. Warren, Fang Fang, Yong Xu, William H. St. Clair
Pages: 771-776
Published online on: 01 October 2006

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Article

Thymidine phosphorylase levels and dihydropyrimidine dehydrogenase levels in non-small cell lung cancer tissues

Masao Chujo, Takashi Miura, Yozo Kawano, Michiyo Miyawaki, Takayuki Imakiire, Yoji Hayashita, Katsunobu Kawahara
Pages: 777-780
Published online on: 01 October 2006

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Article

Breast cancer risk and polymorphisms in genes involved in metabolism of estrogens (CYP17, HSD17β1, COMT and MnSOD): Possible protective role of MnSOD gene polymorphism Val/Ala and Ala/Ala in women that never breast fed

Susana N. Silva, Marisa N. Cabral, Guilherme Bezerra de Castro, Marcelo Pires, Ana Paula Azevedo, Isabel Manita, Julieta Esperança Pina, José Rueff, Jorge Gaspar
Pages: 781-788
Published online on: 01 October 2006

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Article

Epidermal growth factor induction of resistance to topoisomerase II toxins in human squamous carcinoma A431 cells

Wing-Pui Tsang, Siu-Kai Kong, Tim-Tak Kwok
Pages: 789-793
Published online on: 01 October 2006

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Article

Disruption of protein-protein interaction in the Mgl-1 oncoprotein

Yong-Soo Kim, Yu-Kyung Kim, Jung-Mi Park, In-Soo Han, Brijesh S. Ajjappala, Incheol Kang, Kwang-Hyun Baek
Pages: 795-800
Published online on: 01 October 2006

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Article

Linkage disequilibrium of UGT1A1∗6 and UGT1A1∗28 in relation to UGT1A6 and UGT1A7 polymorphisms

Naohito Urawa, Yoshinao Kobayashi, Jun Araki, Ryosuke Sugimoto, Motoh Iwasa, Masahiko Kaito, Yukihko Adachi
Pages: 801-806
Published online on: 01 October 2006

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Article

Evaluation of Ki67, p53 and angiogenesis in patients enrolled in a randomized study of neoadjuvant chemotherapy with or without cystectomy: A southwest oncology group study

H. Barton Grossman, Catherine M. Tangen, Carlos Cordon-Cardo, Richard Cote, Frederic M. Waldman, Ralph W. De Vere White, Anand B. Karnad, Michael Glode, E. David Crawford
Pages: 807-810
Published online on: 01 October 2006

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Article

Missense mutations of BRCA1 gene affect the binding with p53 both in vitro and in vivo

Barbara Quaresima, Maria C. Faniello, Francesco Baudi, Telma Crugliano, Maddalena Di Sanzo, Giovanni Cuda, Francesco Costanzo, Salvatore Venuta
Pages: 811-815
Published online on: 01 October 2006

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Article

Genome-wide cDNA microarray screening of genes related to survival in patients after curative resection of non-small cell lung cancer

Fumihiro Oshita, Akiko Sekiyama, Hiroyuki Ito, Yoichi Kameda, Yohei Miyagi
Pages: 817-821
Published online on: 01 October 2006

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Article

Relationship between E-cadherin, matrix metalloproteinase-7 gene expression and clinicopathological features in gastric carcinoma

Kyung Hee Lee, Sang Joon Shin, Kyeong Ok Kim, Min Kyoung Kim, Myung Soo Hyun, Tae Nyeun Kim, Byung Ik Jang, Sang Woon Kim, Sun Kyo Song, Hee Sun Kim, Sung Hwa Bae, Hun Mo Ryoo
Pages: 823-830
Published online on: 01 October 2006

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Article

Androgen receptor negatively influences the expression of chemokine receptors (CXCR4, CCR1) and ligand-mediated migration in prostate cancer DU-145

Takuya Akashi, Keiichi Koizumi, Osamu Nagakawa, Hideki Fuse, Ikuo Saiki
Pages: 831-836
Published online on: 01 October 2006

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Article

Aging of patients with hepatitis C virus-associated hepatocellular carcinoma: Long-term trends in Japan

Naota Taura, Keisuke Hamasaki, Kazuhiko Nakao, Tatsuki Ichikawa, Daisuke Nishimura, Takashi Goto, Mariko Fukuta, Hiroshi Kawashimo, Hisamitsu Miyaaki, Masumi Fujimoto, Kouichiro Kusumoto, Yasuhide Motoyoshi, Hidetaka Shibata, Kaoru Inokuchi, Katsumi Eguchi
Pages: 837-843
Published online on: 01 October 2006

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Article

MicroRNAs 143 and 145 are possible common onco-microRNAs in human cancers

Yukihiro Akao, Yoshihito Nakagawa, Tomoki Naoe
Pages: 845-850
Published online on: 01 October 2006

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Article

Regulatory roles of cell surface sialylation in sphingolipid-induced cell death in human B cell lymphoma

Osamu Suzuki, Yoshihiro Nozawa, Masafumi Abe
Pages: 851-857
Published online on: 01 October 2006

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Article

skewed X chromosome inactivation of blood cells is associated with early development of lung cancer in females

Gang Li, Qin Su, Gui-Qiu Liu, Li Gong, Wei Zhang, Shao-Jun Zhu, He-Long Zhang, Ying-Ming Feng
Pages: 859-864
Published online on: 01 October 2006

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Article

Alternating hepatic arterial infusion and systemic chemotherapy for stage IV colorectal cancer with synchronous liver metastasis

Masaya Mukai, Yasuhisa Oida, Takayuki Tajima, Kyoko Kishima, Hiromi Ninomiya, Shinkichi Sato, Masato Nakamura, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 865-870
Published online on: 01 October 2006

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Article

Analgesic activity of high-dose intravenous calcitonin in cancer patients with bone metastases

Nicolas Tsavaris, Petros Kopterides, Christos Kosmas, Maria Vadiaka, Antonios Dimitrakopoulos, Helias Scopelitis, Roxanni Tenta, George Vaiopoulos, Christos Koufos
Pages: 871-875
Published online on: 01 October 2006

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Article

A phase II trial with gemcitabine and paclitaxel for the treatment of refractory and relapsed multiple myeloma patients

Yair Gazitt, Paul Shaughnessy, Mace L. Rothenberg
Pages: 877-884
Published online on: 01 October 2006

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Article

Antitumor and antiangiogenic activity of soy isoflavone genistein in mouse models of melanoma and breast cancer

Hernán G. Farina, Monica Pomies, Daniel F. Alonso, Daniel E. Gomez
Pages: 885-891
Published online on: 01 October 2006

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Article

Proliferation studies on chromosome preparations of bone marrow in hematological disease

J.-U. Walther, I. Pohl, A. Rausch, M. Fuehrer
Pages: 893-899
Published online on: 01 October 2006

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Article

Time course of enhanced activity of deoxycytidine kinase and thymidine kinase 1 and 2 in cultured human squamous lung carcinoma cells, SW-1573, induced by γ-irradiation

J. Haveman, J. Sigmond, C. van Bree, N. A. Franken, C. Koedooder, G. J. Peters
Pages: 901-905
Published online on: 01 October 2006

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Article

Paclitaxel and ceramide synergistically induce cell death with transient activation of EGFR and ERK pathway in pancreatic cancer cells

Lihua Qiu, Changlin Zhou, Yun Sun, Wen Di, Erica Scheffler, Sarah Healey, Harold Wanebo, Nicola Kouttab, Wenming Chu, Yinsheng Wan
Pages: 907-913
Published online on: 01 October 2006

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Article

Allelic loss of Hox11L1 gene locus predicts outcome of gastrointestinal stromal tumors

Jussuf T. Kaifi, Meike Wagner, Paulus G. Schurr, Robin Wachowiak, Uta Reichelt, Emre F. Yekebas, Oliver Mann, Yogesh Vashist, Helge Kleinhans, Bjoern-Christian Link, Tim Strate, Viacheslav Kalinin, Jakob R. Izbicki
Pages: 915-919
Published online on: 01 October 2006

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Article

Inhibitory effect of ailanthoidol on 12-O-tetradecanoyl-phorbol-13-acetate-induced tumor promotion in mouse skin

Yean-Jang Lee, Erl-Shyh Kao, Chia-Yih Chu, Wea-Lung Lin, Yea-Huey Chiou, Tsui-Hwa Tseng
Pages: 921-927
Published online on: 01 October 2006

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Article

Metastasis-associated protein 1 enhances angiogenesis by stabilization of HIF-1α

Hyo-Eun Moon, Hwanju Cheon, Kwang-Hoon Chun, Seung Ki Lee, Yong-Sik Kim, Bo-Kyung Jung, Jeong Ae Park, Se-Hee Kim, Joo-Won Jeong, Myung-Shik Lee
Pages: 929-935
Published online on: 01 October 2006

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Genomic instability, postoperative recurrence and therapeutic vulnerabilities in resectable non‑small cell lung cancer (Review)

Linlin Wang, Yong Feng, Qiang Liu
Article Number: 182
Published online on: 28 August 2026

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Review Open Access

Research progress on lactate metabolism in lung cancer: Tumorigenesis, drug resistance and clinical translation (Review)

Yuantao Zhang, Yiyang Shang, Hai Zeng, Ruiling Ning, Xinran Zhang, Dongxu Ao, Jun Cai, Qingqing Ye
Article Number: 181
Published online on: 28 August 2026

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Review Open Access

Decoding the metabolic‑immune crosstalk: The role of glutamine and ammonium reprogramming in prostate cancer immune evasion (Review)

Peilong Wang, Xiaoran Li, Teng Ma, Jun Mi
Article Number: 180
Published online on: 27 August 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells

Jing Guo, Li Chen, Ning Luo, Weihong Yang, Xiaoyan Qu, Zhongping Cheng
Article Number: 179
Published online on: 24 August 2026

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Article Open Access

Combination of lonidamine with devimistat induces synergistic antitumor effects in lung cancer via multifaceted disruption of cellular energy metabolism

Xinhe Bai, Yongfeng Yang, Yuling Luo, Pei Jing, Xia Hong, Yaqin Zou, Yan Dai, Xuping Yang, Meiling Zhou, Han Xiao, Yilan Huang, Shiwei Guo, Qingze Fan
Article Number: 178
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Targeting ribonucleotide reductase M2 subunit by small interfering RNA exerts anti‑oncogenic effects in gastric adenocarcinoma 

Wei Kang, Joanna H.M. Tong, Anthony W.H. Chan, Junhong Zhao, Shiyan Wang, Yujuan Dong, Frankie M.C. Sin, Saifung Yeung, Alfred S.L. Cheng, Jun Yu, Kafai To
Article Number: 177
Published online on: 20 August 2026

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Article Open Access

Cancer‑associated fibroblast‑derived extracellular vesicles promote pancreatic cancer progression via the RAP1B/ANLN axis

Daigo Yoshimori, Mitsuhiro Kudo, Kousuke Ishino, Junji Ueda, Yukako Shintani-Domoto, Akira Matsushita, Youichi Kawano, Takashi Ono, Takahiro Haruna, Kazuhiko Endo, Akira Hamaguchi, Takenori Fujii, Yoko Kawamoto, Kiyoshi Teduka, Taeko Kitamura, Atsushi Masamune, Akihisa Matsuda, Hiroshi Yoshida, Ryuji Ohashi
Article Number: 176
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Restoration of the tumor‑suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells

Dan Jiang, Lingyao Wang, Tong Zhao, Zhaoyu Zhang, Renxia Zhang, Jingji Jin, Yong Cai, Fei Wang
Article Number: 175
Published online on: 17 August 2026

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Review Open Access

Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review)

Shujing Xia, Xiumei Zhang, Lizhong Tang, Anqi Li, Jianhai Chen, Zhang Tao
Article Number: 174
Published online on: 14 August 2026

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Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Correction Open Access

[Corrigendum] TGF‑β1 mediates epithelial to mesenchymal transition via the TGF‑β/Smad pathway in squamous cell carcinoma of the head and neck

Changyun Yu, Yong Liu, Donghai Huang, Yaozhang Dai, Gengming Cai, Jinjie Sun, Ting Xu, Yongquan Tian, Xin Zhang
Article Number: 183
Published online on: 31 August 2026

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