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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2007 Volume 17 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Combination of SN-38 with gefitinib or imatinib overcomes SN-38-resistant small-cell lung cancer cells

Nagio Takigawa, Masami Takeyama, Toshiyuki Kozuki, Takuo Shibayama, Akiko Hisamoto, Katsuyuki Kiura, Atsuhiko Tada, Katsuyuki Hotta, Shigeki Umemura, Kadoaki Ohashi, Yoshiro Fujiwara, Saburo Takata, Eiki Ichihara, Masahiro Osawa, Masahiro Tabata, Mitsune Tanimoto, Kiyoshi Takahashi
Pages: 983-987
Published online on: 01 May 2007

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Article

Diagnostic value of PRND gene expression profiles in astrocytomas: Relationship to tumor grades of malignancy

S. Comincini, V. Ferrara, A. Arias, A. Malovini, A. Azzalin, L. Ferretti, E. Benericetti, M. Cardarelli, M. Gerosa, M. G. Passarin, S. Turazzi, R. Bellazzi
Pages: 989-996
Published online on: 01 May 2007

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Article

Prognostic significance of lymphovascular invasion diagnosed by lymphatic endothelium immunostaining in breast cancer patients

Kenji Tezuka, Naoyoshi Onoda, Tsutomu Takashima, Keiichi Takagaki, Tetsuro Ishikawa, Tomoko Wakasa, Kenichi Wakasa, Kosei Hirakawa
Pages: 997-1003
Published online on: 01 May 2007

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Article

Frequent loss of the long arm of chromosome 18 in esophageal squamous cell carcinoma

Takuya Ando, Hideyuki Ishiguro, Masahiro Kimura, Akira Mitsui, Yoichiro Mori, Nobuyoshi Sugito, Keisuke Tomoda, Ryota Mori, Koshiro Harada, Takeyasu Katada, Ryo Ogawa, Yoshitaka Fujii, Yoshiyuki Kuwabara
Pages: 1005-1011
Published online on: 01 May 2007

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Article

Expression of cyclin A in human leukemia cell line HL-60 following treatment with doxorubicin and etoposide: The potential involvement of cyclin A in apoptosis

Agnieszka Zuryn, Alina Grzanka, Aleksandra Stepien, Dariusz Grzanka, Robert Debski, Dariusz Smolinski
Pages: 1013-1019
Published online on: 01 May 2007

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Article

Immunoexpression of lactoferrin in human sporadic renal cell carcinomas

Giuseppe Giuffrè, Valeria Barresi, Christodoulos Skliros, Gaetano Barresi, Giovanni Tuccari
Pages: 1021-1026
Published online on: 01 May 2007

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Article

Sensitivity to CPT-11 and platinum derivatives of stage III/Dukes' C colorectal cancer with occult neoplastic cells in lymph node sinuses

Masaya Mukai, Shinkichi Sato, Hiromi Ninomiya, Kanako Wakui, Nobukazu Komatsu, Naruaki Matsui, Masato Nakamura, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1027-1032
Published online on: 01 May 2007

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Article

Molecular genetic analyses of the TMPRSS2-ERG and TMPRSS2-ETV1 gene fusions in 50 cases of prostate cancer

Marta Winnes, Erik Lissbrant, Jan-Erik Damber, Göran Stenman
Pages: 1033-1036
Published online on: 01 May 2007

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Article

Correlation of chromosomal imbalances by comparative genomic hybridization and expression of EGFR, PTEN, p53, and MIB-1 in diffuse gliomas

Tahsin Yakut, Angelika Gutenberg, Ahmet Bekar, Unal Egeli, Bastian Gunawan, Ilker Ercan, Sahsene Tolunay, Muammer Doygun, Hans-Jurgen Schulten
Pages: 1037-1043
Published online on: 01 May 2007

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Article

Sensitivity to CPT-11 and platinum derivatives of stage II/Dukes' B colorectal cancer with occult neoplastic cells in lymph node sinuses

Masaya Mukai, Shinkichi Sato, Hiromi Ninomiya, Kanako Wakui, Nobukazu Komatsu, Naruaki Matsui, Masato Nakamura, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1045-1050
Published online on: 01 May 2007

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Article

Sonic hedgehog expression in gastric cancer and gastric adenoma

Sun-Young Lee, Hye Seung Han, Kyung Yung Lee, Tae Sook Hwang, Jeong Hwan Kim, In-Kyung Sung, Hyung-Seok Park, Choon-Jo Jin, Kyoo Wan Choi
Pages: 1051-1055
Published online on: 01 May 2007

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Article

Subcellular localization of KL-6 mucin in colorectal carcinoma cell lines: Association with metastatic potential and cell morphology

Qian Guo, Wei Tang, Yoshinori Inagaki, Norihiro Kokudo, Yasuhiko Sugawara, Hirona Karako, Munehiro Nakata, Masatoshi Makuuchi
Pages: 1057-1060
Published online on: 01 May 2007

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Article

Gene profile analysis of colorectal cancer cell lines by cDNA macroarray

Noboru Saito, Shingo Kameoka, Ryuji Furukawa
Pages: 1061-1065
Published online on: 01 May 2007

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Article

Expression level of Bcl-XL critically affects sensitivity of hepatocellular carcinoma cells to LIGHT-enhanced and interferon-γ-induced apoptosis

Jun Li, Feng Shen, Dong Wu, Li-Xin Wei, Yi-Zhen Wang, Le-Hua Shi, Ying Zou, Meng-Chao Wu
Pages: 1067-1075
Published online on: 01 May 2007

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Article

A successful treatment for metastatic liver tumors from endocrine carcinoma of the stomach

Masako Nishimura, Yoshihide Fujiyama
Pages: 1077-1081
Published online on: 01 May 2007

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Article

Amplification and overexpression of Aurora-A in esophageal squamous cell carcinoma

Shang-Bin Yang, Xiao-Bo Zhou, Hong-Xia Zhu, Lan-Ping Quan, Jin-Feng Bai, Jie He, Yan-Ning Gao, Shu-Jun Cheng, Ning-Zhi Xu
Pages: 1083-1088
Published online on: 01 May 2007

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Article

A gene signature of 8 genes could identify the risk of recurrence and progression in Dukes' B colon cancer patients

Eva Bandrés, Raquel Malumbres, Elena Cubedo, Beatriz Honorato, Ruth Zarate, Alberto Labarga, Unai Gabisu, Jesus Javier Sola, Jesus García-Foncillas
Pages: 1089-1094
Published online on: 01 May 2007

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Article

Loss of Smad4 expression predicts liver metastasis in human colorectal cancer

Lorena Losi, Hanifa Bouzourene, Jean Benhattar
Pages: 1095-1099
Published online on: 01 May 2007

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Article

Altered Calreticulin expression in human colon cancer: Maintenance of Calreticulin expression is associated with mucinous differentiation

C. Toquet, A. Jarry, C. Bou-Hanna, K. Bach, M. G. Denis, J. F. Mosnier, C. L. Laboisse
Pages: 1101-1107
Published online on: 01 May 2007

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Article

Hypoploidy defines patients with poor prognosis in breast cancer

Elisabet Chavez-Uribe, José Cameselle-Teijeiro, Juan E. Viñuela, Carmen Castro-Piñeiro, Francisco Gude, Jerónimo Forteza, José Luis Puente-Domínguez
Pages: 1109-1114
Published online on: 01 May 2007

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Article

Expression of endothelial PDGF receptors α and β in breast cancer: Up-regulation of endothelial PDGF receptor β

T. Vrekoussis, E. N. Stathopoulos, M. Kafousi, I. Navrozoglou, O. Zoras
Pages: 1115-1119
Published online on: 01 May 2007

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Review

HIV infection and cancer in the era of highly active antiretroviral therapy (Review)

Giuseppe Barbaro, Giorgio Barbarini
Pages: 1121-1126
Published online on: 01 May 2007

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Article

Rearrangement and expression of myeov and hst in NIH/3T3 transfectants: A caveat for the interpretation of DNA transfection analyses

Marcus Brecht, Agatha C.M. Steenvoorden, Susanne Luf, Claus R. Bartram, Johannes W.G. Janssen
Pages: 1127-1131
Published online on: 01 May 2007

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Article

A role for cyclic nucleotide phosphodiesterase 4 in regulation of the growth of human malignant melanoma cells

Motoshi Narita, Taku Murata, Kasumi Shimizu, Toshiyuki Nakagawa, Takeo Sugiyama, Madoka Inui, Kenichi Hiramoto, Toshiro Tagawa
Pages: 1133-1139
Published online on: 01 May 2007

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Article

Biodistribution of 211At labeled HER-2 binding affibody molecules in mice

Ann-Charlott Steffen, Ylva Almqvist, Ming-Kuan Chyan, Hans Lundqvist, Vladimir Tolmachev, D. Scott Wilbur, Jörgen Carlsson
Pages: 1141-1147
Published online on: 01 May 2007

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Article

Pitavastatin inactivates NF-κB and decreases IL-6 production through Rho kinase pathway in MCF-7 cells

Juyong Wang, Isao Kitajima
Pages: 1149-1154
Published online on: 01 May 2007

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Article

Bax mutation and overexpression inversely correlate with immature phenotype and prognosis of childhood germ cell tumors

Raffaele Addeo, Stefania Crisci, Velia D'Angelo, Bruno Vincenzi, Fiorina Casale, Guido Pettinato, Vittoria Donofrio, Renata Boldrini, Rita Alaggio, Paola Collini, Roberta Bertorelle, Maria Teresa Di Tullio, Michele Caraglia, Monica Terenziani, Margherita Lo Curto, Paolo Indolfi
Pages: 1155-1161
Published online on: 01 May 2007

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Article

Biological comparison of ovarian cancer resistant cell lines to cisplatin and Taxol by two different administrations

Xue-Dong Yan, Min Li, Ye Yuan, Ning Mao, Ling-Ya Pan
Pages: 1163-1169
Published online on: 01 May 2007

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Article

Analysis of RIN1 gene expression in colorectal cancer

Katsunori Senda, Takanori Goi, Yasuo Hirono, Kanji Katayama, Akio Yamaguchi
Pages: 1171-1175
Published online on: 01 May 2007

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Article

Comparison of CT enhancement patterns and histologic features in hepatocellular carcinoma up to 2 cm: Assessment of malignant potential with claudin-10 immunohistochemistry

Yuichi Sanada, Kazuhiro Yoshida, Hiroyuki Itoh
Pages: 1177-1182
Published online on: 01 May 2007

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Article

Ionizing radiation-induced micronucleus formation is mediated by reactive oxygen species that are produced in a manner dependent on mitochondria, Nox1, and JNK

Kyung-Mi Choi, Chang-Mo Kang, Eun Sook Cho, Seong Man Kang, Seung Bum Lee, Hong-Duck Um
Pages: 1183-1188
Published online on: 01 May 2007

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Article

Antitumor activity of a monoclonal antibody against CD47 in xenograft models of human leukemia

Shinsuke Uno, Yasuko Kinoshita, Yumiko Azuma, Toshiaki Tsunenari, Yasushi Yoshimura, Shinichiro Iida, Yasufumi Kikuchi, Hisafumi Yamada-Okabe, Naoshi Fukushima
Pages: 1189-1194
Published online on: 01 May 2007

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Article

The growth inhibition of liver cancer cells by paclitaxel and the involvement of extracellular signal-regulated kinase and apoptosis

Jun-ichi Okano, Takakazu Nagahara, Kazuya Matsumoto, Yoshikazu Murawaki
Pages: 1195-1200
Published online on: 01 May 2007

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Article

Human equilibrative nucleoside transporter 1 is associated with the chemosensitivity of gemcitabine in human pancreatic adenocarcinoma and biliary tract carcinoma cells

Ryutaro Mori, Takashi Ishikawa, Yasushi Ichikawa, Koichi Taniguchi, Ryusei Matsuyama, Michio Ueda, Yoshiro Fujii, Itaru Endo, Shinji Togo, Peter V. Danenberg, Hiroshi Shimada
Pages: 1201-1205
Published online on: 01 May 2007

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Article

Expression analysis of human intersectin 2 gene (ITSN2) minor splice variants showing differential expression in normal human brain

Markus Seifert, Christina Ampofo, Yasmin Mehraein, Jörg Reichrath, Cornelius Welter
Pages: 1207-1211
Published online on: 01 May 2007

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Article

Functional analysis of the gene expression profiles of colorectal cancer cell lines in relation to oxaliplatin and cisplatin cytotoxicity

Delphine Meynard, Valérie Le Morvan, Jacques Bonnet, Jacques Robert
Pages: 1213-1221
Published online on: 01 May 2007

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Article

Immunohistochemistry of proteins for DNA mismatch repair in correlation to prognostic factors of mammarian cancer

Frank Köster, Andreas Schröer, Dorothea Fischer, Anja-Kathrin Horn, Klaus Diedrich, Michael Friedrich
Pages: 1223-1227
Published online on: 01 May 2007

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Article

Caspase expression profile and functional activity in a panel of breast cancer cell lines

Shihe Yang, Joan Liu, Ann D. Thor, Xiaohe Yang
Pages: 1229-1235
Published online on: 01 May 2007

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Article

Sialylation of intracellular proteins of thyroid lesions

Anna Krzeslak, Zuzanna Gaj, Lech Pomorski, Anna Lipinska
Pages: 1237-1242
Published online on: 01 May 2007

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Article

p53 codon 72 polymorphism, loss of heterozygosity and high-risk human papillomavirus infection in a low-incidence German esophageal squamous cell carcinoma patient cohort

Annette Pantelis, Dimitrios Pantelis, Petra Ruemmele, Arndt Hartmann, Ferdinand Hofstaedter, Reinhard Buettner, Friedrich Bootz, Robert Stoehr
Pages: 1243-1248
Published online on: 01 May 2007

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Article

Generation of anti-tumor response by JAWS II mouse dendritic cells transduced with murine interleukin 12 genes

Elzbieta Pajtasz-Piasecka, Joanna Rossowska, Anna Szyda, Agnieszka Krawczenko, Danuta Dus
Pages: 1249-1257
Published online on: 01 May 2007

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Article

Effects of hypoxia and reoxygenation on the expression levels of the urokinase-type plasminogen activator, its inhibitor plasminogen activator inhibitor type-1 and the urokinase-type plasminogen activator receptor in human head and neck tumour cells

Lisa D. Sprague, Herbert Tomaso, Karin Mengele, Daniela Schilling, Christine Bayer, Peter Stadler, Manfred Schmitt, Michael Molls
Pages: 1259-1268
Published online on: 01 May 2007

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Article

Distinct responses of two hepatocellular carcinoma cell lines of a similar origin to immunotherapies targeting regulatory or effector T cells

Yuji Nagayama, Wataru Hase, Yasuhide Motoyoshi, Ohki Saitoh, Rintaroh Sogawa, Kazuhiko Nakao
Pages: 1269-1273
Published online on: 01 May 2007

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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