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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2007 Volume 17 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Combination of SN-38 with gefitinib or imatinib overcomes SN-38-resistant small-cell lung cancer cells

Nagio Takigawa, Masami Takeyama, Toshiyuki Kozuki, Takuo Shibayama, Akiko Hisamoto, Katsuyuki Kiura, Atsuhiko Tada, Katsuyuki Hotta, Shigeki Umemura, Kadoaki Ohashi, Yoshiro Fujiwara, Saburo Takata, Eiki Ichihara, Masahiro Osawa, Masahiro Tabata, Mitsune Tanimoto, Kiyoshi Takahashi
Pages: 983-987
Published online on: 01 May 2007

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Article

Diagnostic value of PRND gene expression profiles in astrocytomas: Relationship to tumor grades of malignancy

S. Comincini, V. Ferrara, A. Arias, A. Malovini, A. Azzalin, L. Ferretti, E. Benericetti, M. Cardarelli, M. Gerosa, M. G. Passarin, S. Turazzi, R. Bellazzi
Pages: 989-996
Published online on: 01 May 2007

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Article

Prognostic significance of lymphovascular invasion diagnosed by lymphatic endothelium immunostaining in breast cancer patients

Kenji Tezuka, Naoyoshi Onoda, Tsutomu Takashima, Keiichi Takagaki, Tetsuro Ishikawa, Tomoko Wakasa, Kenichi Wakasa, Kosei Hirakawa
Pages: 997-1003
Published online on: 01 May 2007

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Article

Frequent loss of the long arm of chromosome 18 in esophageal squamous cell carcinoma

Takuya Ando, Hideyuki Ishiguro, Masahiro Kimura, Akira Mitsui, Yoichiro Mori, Nobuyoshi Sugito, Keisuke Tomoda, Ryota Mori, Koshiro Harada, Takeyasu Katada, Ryo Ogawa, Yoshitaka Fujii, Yoshiyuki Kuwabara
Pages: 1005-1011
Published online on: 01 May 2007

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Article

Expression of cyclin A in human leukemia cell line HL-60 following treatment with doxorubicin and etoposide: The potential involvement of cyclin A in apoptosis

Agnieszka Zuryn, Alina Grzanka, Aleksandra Stepien, Dariusz Grzanka, Robert Debski, Dariusz Smolinski
Pages: 1013-1019
Published online on: 01 May 2007

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Article

Immunoexpression of lactoferrin in human sporadic renal cell carcinomas

Giuseppe Giuffrè, Valeria Barresi, Christodoulos Skliros, Gaetano Barresi, Giovanni Tuccari
Pages: 1021-1026
Published online on: 01 May 2007

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Article

Sensitivity to CPT-11 and platinum derivatives of stage III/Dukes' C colorectal cancer with occult neoplastic cells in lymph node sinuses

Masaya Mukai, Shinkichi Sato, Hiromi Ninomiya, Kanako Wakui, Nobukazu Komatsu, Naruaki Matsui, Masato Nakamura, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1027-1032
Published online on: 01 May 2007

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Article

Molecular genetic analyses of the TMPRSS2-ERG and TMPRSS2-ETV1 gene fusions in 50 cases of prostate cancer

Marta Winnes, Erik Lissbrant, Jan-Erik Damber, Göran Stenman
Pages: 1033-1036
Published online on: 01 May 2007

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Article

Correlation of chromosomal imbalances by comparative genomic hybridization and expression of EGFR, PTEN, p53, and MIB-1 in diffuse gliomas

Tahsin Yakut, Angelika Gutenberg, Ahmet Bekar, Unal Egeli, Bastian Gunawan, Ilker Ercan, Sahsene Tolunay, Muammer Doygun, Hans-Jurgen Schulten
Pages: 1037-1043
Published online on: 01 May 2007

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Article

Sensitivity to CPT-11 and platinum derivatives of stage II/Dukes' B colorectal cancer with occult neoplastic cells in lymph node sinuses

Masaya Mukai, Shinkichi Sato, Hiromi Ninomiya, Kanako Wakui, Nobukazu Komatsu, Naruaki Matsui, Masato Nakamura, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1045-1050
Published online on: 01 May 2007

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Article

Sonic hedgehog expression in gastric cancer and gastric adenoma

Sun-Young Lee, Hye Seung Han, Kyung Yung Lee, Tae Sook Hwang, Jeong Hwan Kim, In-Kyung Sung, Hyung-Seok Park, Choon-Jo Jin, Kyoo Wan Choi
Pages: 1051-1055
Published online on: 01 May 2007

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Article

Subcellular localization of KL-6 mucin in colorectal carcinoma cell lines: Association with metastatic potential and cell morphology

Qian Guo, Wei Tang, Yoshinori Inagaki, Norihiro Kokudo, Yasuhiko Sugawara, Hirona Karako, Munehiro Nakata, Masatoshi Makuuchi
Pages: 1057-1060
Published online on: 01 May 2007

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Article

Gene profile analysis of colorectal cancer cell lines by cDNA macroarray

Noboru Saito, Shingo Kameoka, Ryuji Furukawa
Pages: 1061-1065
Published online on: 01 May 2007

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Article

Expression level of Bcl-XL critically affects sensitivity of hepatocellular carcinoma cells to LIGHT-enhanced and interferon-γ-induced apoptosis

Jun Li, Feng Shen, Dong Wu, Li-Xin Wei, Yi-Zhen Wang, Le-Hua Shi, Ying Zou, Meng-Chao Wu
Pages: 1067-1075
Published online on: 01 May 2007

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Article

A successful treatment for metastatic liver tumors from endocrine carcinoma of the stomach

Masako Nishimura, Yoshihide Fujiyama
Pages: 1077-1081
Published online on: 01 May 2007

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Article

Amplification and overexpression of Aurora-A in esophageal squamous cell carcinoma

Shang-Bin Yang, Xiao-Bo Zhou, Hong-Xia Zhu, Lan-Ping Quan, Jin-Feng Bai, Jie He, Yan-Ning Gao, Shu-Jun Cheng, Ning-Zhi Xu
Pages: 1083-1088
Published online on: 01 May 2007

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Article

A gene signature of 8 genes could identify the risk of recurrence and progression in Dukes' B colon cancer patients

Eva Bandrés, Raquel Malumbres, Elena Cubedo, Beatriz Honorato, Ruth Zarate, Alberto Labarga, Unai Gabisu, Jesus Javier Sola, Jesus García-Foncillas
Pages: 1089-1094
Published online on: 01 May 2007

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Article

Loss of Smad4 expression predicts liver metastasis in human colorectal cancer

Lorena Losi, Hanifa Bouzourene, Jean Benhattar
Pages: 1095-1099
Published online on: 01 May 2007

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Article

Altered Calreticulin expression in human colon cancer: Maintenance of Calreticulin expression is associated with mucinous differentiation

C. Toquet, A. Jarry, C. Bou-Hanna, K. Bach, M. G. Denis, J. F. Mosnier, C. L. Laboisse
Pages: 1101-1107
Published online on: 01 May 2007

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Article

Hypoploidy defines patients with poor prognosis in breast cancer

Elisabet Chavez-Uribe, José Cameselle-Teijeiro, Juan E. Viñuela, Carmen Castro-Piñeiro, Francisco Gude, Jerónimo Forteza, José Luis Puente-Domínguez
Pages: 1109-1114
Published online on: 01 May 2007

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Article

Expression of endothelial PDGF receptors α and β in breast cancer: Up-regulation of endothelial PDGF receptor β

T. Vrekoussis, E. N. Stathopoulos, M. Kafousi, I. Navrozoglou, O. Zoras
Pages: 1115-1119
Published online on: 01 May 2007

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Review

HIV infection and cancer in the era of highly active antiretroviral therapy (Review)

Giuseppe Barbaro, Giorgio Barbarini
Pages: 1121-1126
Published online on: 01 May 2007

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Article

Rearrangement and expression of myeov and hst in NIH/3T3 transfectants: A caveat for the interpretation of DNA transfection analyses

Marcus Brecht, Agatha C.M. Steenvoorden, Susanne Luf, Claus R. Bartram, Johannes W.G. Janssen
Pages: 1127-1131
Published online on: 01 May 2007

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Article

A role for cyclic nucleotide phosphodiesterase 4 in regulation of the growth of human malignant melanoma cells

Motoshi Narita, Taku Murata, Kasumi Shimizu, Toshiyuki Nakagawa, Takeo Sugiyama, Madoka Inui, Kenichi Hiramoto, Toshiro Tagawa
Pages: 1133-1139
Published online on: 01 May 2007

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Article

Biodistribution of 211At labeled HER-2 binding affibody molecules in mice

Ann-Charlott Steffen, Ylva Almqvist, Ming-Kuan Chyan, Hans Lundqvist, Vladimir Tolmachev, D. Scott Wilbur, Jörgen Carlsson
Pages: 1141-1147
Published online on: 01 May 2007

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Article

Pitavastatin inactivates NF-κB and decreases IL-6 production through Rho kinase pathway in MCF-7 cells

Juyong Wang, Isao Kitajima
Pages: 1149-1154
Published online on: 01 May 2007

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Article

Bax mutation and overexpression inversely correlate with immature phenotype and prognosis of childhood germ cell tumors

Raffaele Addeo, Stefania Crisci, Velia D'Angelo, Bruno Vincenzi, Fiorina Casale, Guido Pettinato, Vittoria Donofrio, Renata Boldrini, Rita Alaggio, Paola Collini, Roberta Bertorelle, Maria Teresa Di Tullio, Michele Caraglia, Monica Terenziani, Margherita Lo Curto, Paolo Indolfi
Pages: 1155-1161
Published online on: 01 May 2007

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Article

Biological comparison of ovarian cancer resistant cell lines to cisplatin and Taxol by two different administrations

Xue-Dong Yan, Min Li, Ye Yuan, Ning Mao, Ling-Ya Pan
Pages: 1163-1169
Published online on: 01 May 2007

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Article

Analysis of RIN1 gene expression in colorectal cancer

Katsunori Senda, Takanori Goi, Yasuo Hirono, Kanji Katayama, Akio Yamaguchi
Pages: 1171-1175
Published online on: 01 May 2007

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Article

Comparison of CT enhancement patterns and histologic features in hepatocellular carcinoma up to 2 cm: Assessment of malignant potential with claudin-10 immunohistochemistry

Yuichi Sanada, Kazuhiro Yoshida, Hiroyuki Itoh
Pages: 1177-1182
Published online on: 01 May 2007

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Article

Ionizing radiation-induced micronucleus formation is mediated by reactive oxygen species that are produced in a manner dependent on mitochondria, Nox1, and JNK

Kyung-Mi Choi, Chang-Mo Kang, Eun Sook Cho, Seong Man Kang, Seung Bum Lee, Hong-Duck Um
Pages: 1183-1188
Published online on: 01 May 2007

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Article

Antitumor activity of a monoclonal antibody against CD47 in xenograft models of human leukemia

Shinsuke Uno, Yasuko Kinoshita, Yumiko Azuma, Toshiaki Tsunenari, Yasushi Yoshimura, Shinichiro Iida, Yasufumi Kikuchi, Hisafumi Yamada-Okabe, Naoshi Fukushima
Pages: 1189-1194
Published online on: 01 May 2007

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Article

The growth inhibition of liver cancer cells by paclitaxel and the involvement of extracellular signal-regulated kinase and apoptosis

Jun-ichi Okano, Takakazu Nagahara, Kazuya Matsumoto, Yoshikazu Murawaki
Pages: 1195-1200
Published online on: 01 May 2007

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Article

Human equilibrative nucleoside transporter 1 is associated with the chemosensitivity of gemcitabine in human pancreatic adenocarcinoma and biliary tract carcinoma cells

Ryutaro Mori, Takashi Ishikawa, Yasushi Ichikawa, Koichi Taniguchi, Ryusei Matsuyama, Michio Ueda, Yoshiro Fujii, Itaru Endo, Shinji Togo, Peter V. Danenberg, Hiroshi Shimada
Pages: 1201-1205
Published online on: 01 May 2007

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Article

Expression analysis of human intersectin 2 gene (ITSN2) minor splice variants showing differential expression in normal human brain

Markus Seifert, Christina Ampofo, Yasmin Mehraein, Jörg Reichrath, Cornelius Welter
Pages: 1207-1211
Published online on: 01 May 2007

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Article

Functional analysis of the gene expression profiles of colorectal cancer cell lines in relation to oxaliplatin and cisplatin cytotoxicity

Delphine Meynard, Valérie Le Morvan, Jacques Bonnet, Jacques Robert
Pages: 1213-1221
Published online on: 01 May 2007

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Article

Immunohistochemistry of proteins for DNA mismatch repair in correlation to prognostic factors of mammarian cancer

Frank Köster, Andreas Schröer, Dorothea Fischer, Anja-Kathrin Horn, Klaus Diedrich, Michael Friedrich
Pages: 1223-1227
Published online on: 01 May 2007

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Article

Caspase expression profile and functional activity in a panel of breast cancer cell lines

Shihe Yang, Joan Liu, Ann D. Thor, Xiaohe Yang
Pages: 1229-1235
Published online on: 01 May 2007

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Article

Sialylation of intracellular proteins of thyroid lesions

Anna Krzeslak, Zuzanna Gaj, Lech Pomorski, Anna Lipinska
Pages: 1237-1242
Published online on: 01 May 2007

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Article

p53 codon 72 polymorphism, loss of heterozygosity and high-risk human papillomavirus infection in a low-incidence German esophageal squamous cell carcinoma patient cohort

Annette Pantelis, Dimitrios Pantelis, Petra Ruemmele, Arndt Hartmann, Ferdinand Hofstaedter, Reinhard Buettner, Friedrich Bootz, Robert Stoehr
Pages: 1243-1248
Published online on: 01 May 2007

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Article

Generation of anti-tumor response by JAWS II mouse dendritic cells transduced with murine interleukin 12 genes

Elzbieta Pajtasz-Piasecka, Joanna Rossowska, Anna Szyda, Agnieszka Krawczenko, Danuta Dus
Pages: 1249-1257
Published online on: 01 May 2007

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Article

Effects of hypoxia and reoxygenation on the expression levels of the urokinase-type plasminogen activator, its inhibitor plasminogen activator inhibitor type-1 and the urokinase-type plasminogen activator receptor in human head and neck tumour cells

Lisa D. Sprague, Herbert Tomaso, Karin Mengele, Daniela Schilling, Christine Bayer, Peter Stadler, Manfred Schmitt, Michael Molls
Pages: 1259-1268
Published online on: 01 May 2007

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Article

Distinct responses of two hepatocellular carcinoma cell lines of a similar origin to immunotherapies targeting regulatory or effector T cells

Yuji Nagayama, Wataru Hase, Yasuhide Motoyoshi, Ohki Saitoh, Rintaroh Sogawa, Kazuhiko Nakao
Pages: 1269-1273
Published online on: 01 May 2007

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Journal Cover
November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Targeting the DNHD1‑HDAC6 axis inactivates prostate cancer cell aggressiveness in vitro, suggesting potential therapeutic vulnerability

An Ni Lee, Chia Chang Wu, Su Wei Hu, Chih Heng Chen, Yi Te Chiang, Wei Tang Kao, Kai Yi Tzou, Chia Hung Liu, Shao Wei Dong, Yu Ting Wang, Yueh Lin Lee, Siou Bi Li, Che An Wu, Chiao Chun Liao, Ming Hsien Chan, Po Han Chiu, Chien Hsiu Li
Article Number: 198
Published online on: 30 September 2026

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Article Open Access

Loperamide enhances the radiosensitivity of cervical cancer cells via ferroptosis induction

Huarong Guo, Haixia Li, Shunkang Tian, Yunkai Zhang, Fuyun Wu, Jing Ke
Article Number: 197
Published online on: 30 September 2026

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Review Open Access

Mitochondrial mechanisms underlying spatial immune phenotypes in non‑small cell lung cancer: Implications for ICI response and cold‑to‑hot tumor conversion (Review)

Hongyi Lai, Ke Sun, Tong Mu, Xi Liu, Mingshan Liu
Article Number: 196
Published online on: 30 September 2026

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Article Open Access

PINK1 promotes the progression of lung squamous cell carcinoma through the FAK/AKT/RhoA/vinculin pathway

Xu Li, Yuhui Ma
Article Number: 195
Published online on: 29 September 2026

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Expression of Concern Open Access

[Expression of Concern] MicroRNA‑195‑5p is a potential diagnostic and therapeutic target for breast cancer

Qifeng Luo, Chuankui Wei, Xiaoyu Li, Jia Li, Lei Chen, Yixiang Huang, Hongming Song, Dengfeng Li, Lin Fang
Article Number: 194
Published online on: 23 September 2026

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Article Open Access

SGPP1 as a tumor suppressor in esophageal squamous cell carcinoma: Potential molecular mechanisms involving UGT1A9/UGT2B28 and clinical prognostic significance

Linlin Su, Liubing Hou, Xuetao Han, Ge Zhang, Jiayuan Li, Yu Wang, Yuxin Han, Xiaoying Xue, Huandi Zhou
Article Number: 193
Published online on: 23 September 2026

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Correction Open Access

[Corrigendum] High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer

Yahua Chen, Jun Liu, Wei Wang, Li Xiang, Jide Wang, Side Liu, Hongyan Zhou, Zheng Guo
Article Number: 192
Published online on: 21 September 2026

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Review Open Access

Overcoming melanoma drug resistance: Mechanisms and clinical progress of oncolytic viruses combined with immune checkpoint inhibitors (Review)

Yuan He, Wenxuan Lin, Haofang Chen, Yongqi Guan, Congcong Guan, Yanxiang Zhang, Dongsheng Pan
Article Number: 191
Published online on: 17 September 2026

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Article Open Access

Validation of next‑generation sequencing‑derived circulating mRNA variants as potential diagnostic tools in hepatocellular carcinoma and cholangiocarcinoma

Daniel Zezulinski, Maarouf A. Hoteit, David E. Kaplan, Tingting Zhan, Cataldo Doria, Timothy M. Block, Aejaz Sayeed
Article Number: 190
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer

Le Hong, Gen Sun, Long Peng, Yi Tu, Zhen Wan, Haiwei Xiong, Yong Li, Weidong Xiao
Article Number: 189
Published online on: 16 September 2026

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Article Open Access

Pemetrexed increases BRCA1 protein stability and sensitizes TNBC cells to radiotherapy

Hee Jin, Kyung-Hwa Jeon, Chaerin Kang, Joohyun Lee, Yeonjin Lee, Youngjoo Kwon, Yun-Sil Lee
Article Number: 188
Published online on: 15 September 2026

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Article Open Access

FXYD5 promotes the growth of glioblastoma by targeting the PI3K/AKT/ACSL4 signaling axis

Bang Wang, Yong Qin, Hang Cheng, Yibin Zeng, Lianglei Jiang, Xuebin Hu
Article Number: 187
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] RIP kinase‑mediated ROS production triggers XAF1 expression through activation of TAp73 in casticin‑treated bladder cancer cells

Yoon Hee Chung, Daejin Kim
Article Number: 186
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo activities of an antitumor peptide HM‑3: A special dose‑efficacy relationship on an HCT‑116 xenograft model in nude mice

Sitelbanat Yassin, Jialiang Hu, Hanmei Xu, Ce Li, Sarra Setrerrahmane
Article Number: 185
Published online on: 10 September 2026

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Article Open Access

Effect of EZH2 regulation of the JAK2/STAT3 signaling pathway on proliferation and apoptosis in non‑small cell lung cancer cells

Shuang Wu, Wei Zhang
Article Number: 184
Published online on: 08 September 2026

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Correction Open Access

[Corrigendum] TGF‑β1 mediates epithelial to mesenchymal transition via the TGF‑β/Smad pathway in squamous cell carcinoma of the head and neck

Changyun Yu, Yong Liu, Donghai Huang, Yaozhang Dai, Gengming Cai, Jinjie Sun, Ting Xu, Yongquan Tian, Xin Zhang
Article Number: 183
Published online on: 31 August 2026

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December-2026 Volume 56 Issue 6

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Expression of Concern Open Access

[Expression of Concern] ZNF703 promotes tumor cell proliferation and invasion and predicts poor prognosis in patients with colorectal cancer

Feng Ma, Lihong Bi, Gongli Yang, Mengnan Zhang, Cuiping Liu, Yingying Zhao, Yadong Wang, Jide Wang, Yang Bai, Yali Zhang
Article Number: 199
Published online on: 30 September 2026

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