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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2007 Volume 17 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Combination of SN-38 with gefitinib or imatinib overcomes SN-38-resistant small-cell lung cancer cells

Nagio Takigawa, Masami Takeyama, Toshiyuki Kozuki, Takuo Shibayama, Akiko Hisamoto, Katsuyuki Kiura, Atsuhiko Tada, Katsuyuki Hotta, Shigeki Umemura, Kadoaki Ohashi, Yoshiro Fujiwara, Saburo Takata, Eiki Ichihara, Masahiro Osawa, Masahiro Tabata, Mitsune Tanimoto, Kiyoshi Takahashi
Pages: 983-987
Published online on: 01 May 2007

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Article

Diagnostic value of PRND gene expression profiles in astrocytomas: Relationship to tumor grades of malignancy

S. Comincini, V. Ferrara, A. Arias, A. Malovini, A. Azzalin, L. Ferretti, E. Benericetti, M. Cardarelli, M. Gerosa, M. G. Passarin, S. Turazzi, R. Bellazzi
Pages: 989-996
Published online on: 01 May 2007

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Article

Prognostic significance of lymphovascular invasion diagnosed by lymphatic endothelium immunostaining in breast cancer patients

Kenji Tezuka, Naoyoshi Onoda, Tsutomu Takashima, Keiichi Takagaki, Tetsuro Ishikawa, Tomoko Wakasa, Kenichi Wakasa, Kosei Hirakawa
Pages: 997-1003
Published online on: 01 May 2007

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Article

Frequent loss of the long arm of chromosome 18 in esophageal squamous cell carcinoma

Takuya Ando, Hideyuki Ishiguro, Masahiro Kimura, Akira Mitsui, Yoichiro Mori, Nobuyoshi Sugito, Keisuke Tomoda, Ryota Mori, Koshiro Harada, Takeyasu Katada, Ryo Ogawa, Yoshitaka Fujii, Yoshiyuki Kuwabara
Pages: 1005-1011
Published online on: 01 May 2007

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Article

Expression of cyclin A in human leukemia cell line HL-60 following treatment with doxorubicin and etoposide: The potential involvement of cyclin A in apoptosis

Agnieszka Zuryn, Alina Grzanka, Aleksandra Stepien, Dariusz Grzanka, Robert Debski, Dariusz Smolinski
Pages: 1013-1019
Published online on: 01 May 2007

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Article

Immunoexpression of lactoferrin in human sporadic renal cell carcinomas

Giuseppe Giuffrè, Valeria Barresi, Christodoulos Skliros, Gaetano Barresi, Giovanni Tuccari
Pages: 1021-1026
Published online on: 01 May 2007

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Article

Sensitivity to CPT-11 and platinum derivatives of stage III/Dukes' C colorectal cancer with occult neoplastic cells in lymph node sinuses

Masaya Mukai, Shinkichi Sato, Hiromi Ninomiya, Kanako Wakui, Nobukazu Komatsu, Naruaki Matsui, Masato Nakamura, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1027-1032
Published online on: 01 May 2007

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Article

Molecular genetic analyses of the TMPRSS2-ERG and TMPRSS2-ETV1 gene fusions in 50 cases of prostate cancer

Marta Winnes, Erik Lissbrant, Jan-Erik Damber, Göran Stenman
Pages: 1033-1036
Published online on: 01 May 2007

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Article

Correlation of chromosomal imbalances by comparative genomic hybridization and expression of EGFR, PTEN, p53, and MIB-1 in diffuse gliomas

Tahsin Yakut, Angelika Gutenberg, Ahmet Bekar, Unal Egeli, Bastian Gunawan, Ilker Ercan, Sahsene Tolunay, Muammer Doygun, Hans-Jurgen Schulten
Pages: 1037-1043
Published online on: 01 May 2007

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Article

Sensitivity to CPT-11 and platinum derivatives of stage II/Dukes' B colorectal cancer with occult neoplastic cells in lymph node sinuses

Masaya Mukai, Shinkichi Sato, Hiromi Ninomiya, Kanako Wakui, Nobukazu Komatsu, Naruaki Matsui, Masato Nakamura, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1045-1050
Published online on: 01 May 2007

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Article

Sonic hedgehog expression in gastric cancer and gastric adenoma

Sun-Young Lee, Hye Seung Han, Kyung Yung Lee, Tae Sook Hwang, Jeong Hwan Kim, In-Kyung Sung, Hyung-Seok Park, Choon-Jo Jin, Kyoo Wan Choi
Pages: 1051-1055
Published online on: 01 May 2007

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Article

Subcellular localization of KL-6 mucin in colorectal carcinoma cell lines: Association with metastatic potential and cell morphology

Qian Guo, Wei Tang, Yoshinori Inagaki, Norihiro Kokudo, Yasuhiko Sugawara, Hirona Karako, Munehiro Nakata, Masatoshi Makuuchi
Pages: 1057-1060
Published online on: 01 May 2007

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Article

Gene profile analysis of colorectal cancer cell lines by cDNA macroarray

Noboru Saito, Shingo Kameoka, Ryuji Furukawa
Pages: 1061-1065
Published online on: 01 May 2007

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Article

Expression level of Bcl-XL critically affects sensitivity of hepatocellular carcinoma cells to LIGHT-enhanced and interferon-γ-induced apoptosis

Jun Li, Feng Shen, Dong Wu, Li-Xin Wei, Yi-Zhen Wang, Le-Hua Shi, Ying Zou, Meng-Chao Wu
Pages: 1067-1075
Published online on: 01 May 2007

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Article

A successful treatment for metastatic liver tumors from endocrine carcinoma of the stomach

Masako Nishimura, Yoshihide Fujiyama
Pages: 1077-1081
Published online on: 01 May 2007

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Article

Amplification and overexpression of Aurora-A in esophageal squamous cell carcinoma

Shang-Bin Yang, Xiao-Bo Zhou, Hong-Xia Zhu, Lan-Ping Quan, Jin-Feng Bai, Jie He, Yan-Ning Gao, Shu-Jun Cheng, Ning-Zhi Xu
Pages: 1083-1088
Published online on: 01 May 2007

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Article

A gene signature of 8 genes could identify the risk of recurrence and progression in Dukes' B colon cancer patients

Eva Bandrés, Raquel Malumbres, Elena Cubedo, Beatriz Honorato, Ruth Zarate, Alberto Labarga, Unai Gabisu, Jesus Javier Sola, Jesus García-Foncillas
Pages: 1089-1094
Published online on: 01 May 2007

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Article

Loss of Smad4 expression predicts liver metastasis in human colorectal cancer

Lorena Losi, Hanifa Bouzourene, Jean Benhattar
Pages: 1095-1099
Published online on: 01 May 2007

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Article

Altered Calreticulin expression in human colon cancer: Maintenance of Calreticulin expression is associated with mucinous differentiation

C. Toquet, A. Jarry, C. Bou-Hanna, K. Bach, M. G. Denis, J. F. Mosnier, C. L. Laboisse
Pages: 1101-1107
Published online on: 01 May 2007

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Article

Hypoploidy defines patients with poor prognosis in breast cancer

Elisabet Chavez-Uribe, José Cameselle-Teijeiro, Juan E. Viñuela, Carmen Castro-Piñeiro, Francisco Gude, Jerónimo Forteza, José Luis Puente-Domínguez
Pages: 1109-1114
Published online on: 01 May 2007

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Article

Expression of endothelial PDGF receptors α and β in breast cancer: Up-regulation of endothelial PDGF receptor β

T. Vrekoussis, E. N. Stathopoulos, M. Kafousi, I. Navrozoglou, O. Zoras
Pages: 1115-1119
Published online on: 01 May 2007

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Review

HIV infection and cancer in the era of highly active antiretroviral therapy (Review)

Giuseppe Barbaro, Giorgio Barbarini
Pages: 1121-1126
Published online on: 01 May 2007

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Article

Rearrangement and expression of myeov and hst in NIH/3T3 transfectants: A caveat for the interpretation of DNA transfection analyses

Marcus Brecht, Agatha C.M. Steenvoorden, Susanne Luf, Claus R. Bartram, Johannes W.G. Janssen
Pages: 1127-1131
Published online on: 01 May 2007

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Article

A role for cyclic nucleotide phosphodiesterase 4 in regulation of the growth of human malignant melanoma cells

Motoshi Narita, Taku Murata, Kasumi Shimizu, Toshiyuki Nakagawa, Takeo Sugiyama, Madoka Inui, Kenichi Hiramoto, Toshiro Tagawa
Pages: 1133-1139
Published online on: 01 May 2007

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Article

Biodistribution of 211At labeled HER-2 binding affibody molecules in mice

Ann-Charlott Steffen, Ylva Almqvist, Ming-Kuan Chyan, Hans Lundqvist, Vladimir Tolmachev, D. Scott Wilbur, Jörgen Carlsson
Pages: 1141-1147
Published online on: 01 May 2007

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Article

Pitavastatin inactivates NF-κB and decreases IL-6 production through Rho kinase pathway in MCF-7 cells

Juyong Wang, Isao Kitajima
Pages: 1149-1154
Published online on: 01 May 2007

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Article

Bax mutation and overexpression inversely correlate with immature phenotype and prognosis of childhood germ cell tumors

Raffaele Addeo, Stefania Crisci, Velia D'Angelo, Bruno Vincenzi, Fiorina Casale, Guido Pettinato, Vittoria Donofrio, Renata Boldrini, Rita Alaggio, Paola Collini, Roberta Bertorelle, Maria Teresa Di Tullio, Michele Caraglia, Monica Terenziani, Margherita Lo Curto, Paolo Indolfi
Pages: 1155-1161
Published online on: 01 May 2007

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Article

Biological comparison of ovarian cancer resistant cell lines to cisplatin and Taxol by two different administrations

Xue-Dong Yan, Min Li, Ye Yuan, Ning Mao, Ling-Ya Pan
Pages: 1163-1169
Published online on: 01 May 2007

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Article

Analysis of RIN1 gene expression in colorectal cancer

Katsunori Senda, Takanori Goi, Yasuo Hirono, Kanji Katayama, Akio Yamaguchi
Pages: 1171-1175
Published online on: 01 May 2007

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Article

Comparison of CT enhancement patterns and histologic features in hepatocellular carcinoma up to 2 cm: Assessment of malignant potential with claudin-10 immunohistochemistry

Yuichi Sanada, Kazuhiro Yoshida, Hiroyuki Itoh
Pages: 1177-1182
Published online on: 01 May 2007

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Article

Ionizing radiation-induced micronucleus formation is mediated by reactive oxygen species that are produced in a manner dependent on mitochondria, Nox1, and JNK

Kyung-Mi Choi, Chang-Mo Kang, Eun Sook Cho, Seong Man Kang, Seung Bum Lee, Hong-Duck Um
Pages: 1183-1188
Published online on: 01 May 2007

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Article

Antitumor activity of a monoclonal antibody against CD47 in xenograft models of human leukemia

Shinsuke Uno, Yasuko Kinoshita, Yumiko Azuma, Toshiaki Tsunenari, Yasushi Yoshimura, Shinichiro Iida, Yasufumi Kikuchi, Hisafumi Yamada-Okabe, Naoshi Fukushima
Pages: 1189-1194
Published online on: 01 May 2007

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Article

The growth inhibition of liver cancer cells by paclitaxel and the involvement of extracellular signal-regulated kinase and apoptosis

Jun-ichi Okano, Takakazu Nagahara, Kazuya Matsumoto, Yoshikazu Murawaki
Pages: 1195-1200
Published online on: 01 May 2007

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Article

Human equilibrative nucleoside transporter 1 is associated with the chemosensitivity of gemcitabine in human pancreatic adenocarcinoma and biliary tract carcinoma cells

Ryutaro Mori, Takashi Ishikawa, Yasushi Ichikawa, Koichi Taniguchi, Ryusei Matsuyama, Michio Ueda, Yoshiro Fujii, Itaru Endo, Shinji Togo, Peter V. Danenberg, Hiroshi Shimada
Pages: 1201-1205
Published online on: 01 May 2007

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Article

Expression analysis of human intersectin 2 gene (ITSN2) minor splice variants showing differential expression in normal human brain

Markus Seifert, Christina Ampofo, Yasmin Mehraein, Jörg Reichrath, Cornelius Welter
Pages: 1207-1211
Published online on: 01 May 2007

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Article

Functional analysis of the gene expression profiles of colorectal cancer cell lines in relation to oxaliplatin and cisplatin cytotoxicity

Delphine Meynard, Valérie Le Morvan, Jacques Bonnet, Jacques Robert
Pages: 1213-1221
Published online on: 01 May 2007

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Article

Immunohistochemistry of proteins for DNA mismatch repair in correlation to prognostic factors of mammarian cancer

Frank Köster, Andreas Schröer, Dorothea Fischer, Anja-Kathrin Horn, Klaus Diedrich, Michael Friedrich
Pages: 1223-1227
Published online on: 01 May 2007

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Article

Caspase expression profile and functional activity in a panel of breast cancer cell lines

Shihe Yang, Joan Liu, Ann D. Thor, Xiaohe Yang
Pages: 1229-1235
Published online on: 01 May 2007

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Article

Sialylation of intracellular proteins of thyroid lesions

Anna Krzeslak, Zuzanna Gaj, Lech Pomorski, Anna Lipinska
Pages: 1237-1242
Published online on: 01 May 2007

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Article

p53 codon 72 polymorphism, loss of heterozygosity and high-risk human papillomavirus infection in a low-incidence German esophageal squamous cell carcinoma patient cohort

Annette Pantelis, Dimitrios Pantelis, Petra Ruemmele, Arndt Hartmann, Ferdinand Hofstaedter, Reinhard Buettner, Friedrich Bootz, Robert Stoehr
Pages: 1243-1248
Published online on: 01 May 2007

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Article

Generation of anti-tumor response by JAWS II mouse dendritic cells transduced with murine interleukin 12 genes

Elzbieta Pajtasz-Piasecka, Joanna Rossowska, Anna Szyda, Agnieszka Krawczenko, Danuta Dus
Pages: 1249-1257
Published online on: 01 May 2007

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Article

Effects of hypoxia and reoxygenation on the expression levels of the urokinase-type plasminogen activator, its inhibitor plasminogen activator inhibitor type-1 and the urokinase-type plasminogen activator receptor in human head and neck tumour cells

Lisa D. Sprague, Herbert Tomaso, Karin Mengele, Daniela Schilling, Christine Bayer, Peter Stadler, Manfred Schmitt, Michael Molls
Pages: 1259-1268
Published online on: 01 May 2007

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Article

Distinct responses of two hepatocellular carcinoma cell lines of a similar origin to immunotherapies targeting regulatory or effector T cells

Yuji Nagayama, Wataru Hase, Yasuhide Motoyoshi, Ohki Saitoh, Rintaroh Sogawa, Kazuhiko Nakao
Pages: 1269-1273
Published online on: 01 May 2007

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Research progress on plant polysaccharides in the prevention and treatment of tumors (Review)

Jikun Wang, Yihan Wang, Xiwu Zhang
Article Number: 152
Published online on: 26 June 2026

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Article Open Access

PIN1 inhibits ferroptosis in gastric cancer cells by regulating the CPEB1‑GPX4 pathway

Aoran Zeng, Tao Wang, Jie Song, Lili Zhu, Ling Chen, Qi Yuan, Ying Jiang, Ping Zhang, Shengzhong Rong, Jing Wang
Article Number: 151
Published online on: 24 June 2026

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Review Open Access

Tanshinone IIA in breast cancer: Molecular mechanisms, structural optimization and translational challenges (Review)

Xiuxia Li, Linlin Feng
Article Number: 150
Published online on: 23 June 2026

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Retraction Open Access

[Retracted] Kevetrin induces apoptosis in TP53 wild‑type and mutant acute myeloid leukemia cells

Roberta Napolitano, Serena De Matteis, Silvia Carloni, Samantha Bruno, Giulia Abbati, Laura Capelli, Martina Ghetti, Maria Teresa Bochicchio, Chiara Liverani, Laura Mercatali, Daniele Calistri, Antonio Cuneo, Krishna Menon, Gerardo Musuraca, Giovanni Martinelli, Giorgia Simonetti
Article Number: 149
Published online on: 22 June 2026

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Article Open Access

PI3Kδ inhibitor YY‑20394 is effective alone or in combination with Bcl‑2 inhibitor ABT199 in acute myeloid leukemia cells

Yinghua Geng, Lili Zhou, Yan Lou, Jiaqi Chen, Qi Liu, Ji Shen, Yanli Yang, Wenjuan Wu
Article Number: 148
Published online on: 17 June 2026

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Article Open Access

Schisandrin B exhibits anti‑proliferative effects by inducing ferroptosis in pancreatic cancer

Fengjin Li, Jiacai Fu, Xiaowei Lin, Yanting Liu, Lu Yang, Yuxin Li, Tieli Peng, Ling Qi
Article Number: 147
Published online on: 16 June 2026

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Review

Research advances on DKK1 in head and neck squamous cell carcinoma: Linking molecular mechanisms to clinical applications (Review)

Xiaoqian Zhu, Liwei Hong, Weihan Chen, Junjuan Tan, Juju Zhou, Lingya Yang, Yonglin Liu, Tiantian Zhai, Kai Chen
Article Number: 146
Published online on: 16 June 2026

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Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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Journal Cover
September-2026 Volume 56 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Correction Open Access

[Corrigendum] Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway

Qingkai Zhang, Xufeng Tao, Shilin Xia, Jialin Qu, Huiyi Song, Jianjun Liu, Hailong Li, Dong Shang
Article Number: 158
Published online on: 15 July 2026

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TM6SF2 overexpression suppresses the proliferation and promotes apoptosis of human hepatocellular carcinoma cells

Ziyou Huai, Wanying Xue, Xinxiao Jin, Shiyu Peng, Wenqiang Xu, Shujing Li, Huanfeng Hao, Yuanyuan Wang
Article Number: 157
Published online on: 14 July 2026

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Correction Open Access

[Corrigendum] VDAC upregulation and αTAT1‑mediated α‑tubulin acetylation contribute to tanespimycin‑induced apoptosis in Calu‑1 cells

Qilin Wang, Xiangguo Liu
Article Number: 156
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells

Annamaria Spina, Luca Sorvillo, Emilio Chiosi, Antonietta Esposito, Francesca Di Maiolo, Luigi Sapio, Michele Caraglia, Silvio Naviglio
Article Number: 155
Published online on: 06 July 2026

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Article Open Access

Identification of RRM2 as a key regulator of malignant epithelial cells in gastric cancer through single‑cell transcriptomics

Xinzhen Cai, Yun He, Lili Kang, Dongli Zhou, Mengmeng Wang, Tianyu Ma
Article Number: 154
Published online on: 03 July 2026

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Article

Impact of WFDC2 on the biological functions of cervical cancer cells and the regulation of the ERK/NF‑κB signaling pathway

Yanping Zhang, Hongling Zou, Shufeng Deng, Lvling Zou, Mingzhu Xia, Limin Tao
Article Number: 153
Published online on: 01 July 2026

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