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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2009 Volume 22 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Epigenetic alterations associated with cholangiocarcinoma (Review)

Hajime Isomoto
Pages: 227-232
Published online on: 01 August 2009

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Review

Molecular pathogenesis of endometriosis-associated clear cell carcinoma of the ovary (Review)

Hiroshi Kobayashi, Hirotaka Kajiwara, Seiji Kanayama, Yoshihiko Yamada, Naoto Furukawa, Taketoshi Noguchi, Shoji Haruta, Shozo Yoshida, Mariko Sakata, Toshiyuki Sado, Hidekazu Oi
Pages: 233-240
Published online on: 01 August 2009

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Article Open Access

Antitumor activity of bevacizumab in combination with capecitabine and oxaliplatin in human colorectal cancer xenograft models

Mieko Yanagisawa, Kaori Fujimoto-Ouchi, Keigo Yorozu, Yoriko Yamashita, Kazushige Mori
Pages: 241-247
Published online on: 01 August 2009

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Article

hnRNP U interacts with the c-Myc-Max complex on the E-box promoter region inducing the ornithine decarboxylase gene

Yoichiro Matsuoka, Norihisa Uehara, Airo Tsubura
Pages: 249-255
Published online on: 01 August 2009

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Article

Proliferation of estrogen-responsive mouse tumor cell line B-1F stimulated by Saiboku-to, but inhibited by Scutellaria baicalensis, a component of Saiboku-to

Teruko Murashima, Megumi Yamasaki, Yoshio Nishizawa, Hiroshi Katayama, Yumiko Tanigaki, Yoshiko Saeki, Kimura Shojiro, Yasuko Nishizawa
Pages: 257-264
Published online on: 01 August 2009

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Article

Differences in expression between transcripts using alternative promoters of hMLH1 gene and their correlation with microsatellite instability

Ryosuke Takahashi, Keiichi Nagai
Pages: 265-271
Published online on: 01 August 2009

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Article

A low number of tumor-infiltrating FOXP3-positive cells during primary systemic chemotherapy correlates with favorable anti-tumor response in patients with breast cancer

Tomoyuki Aruga, Eiji Suzuki, Shigehira Saji, Shin-Ichirou Horiguchi, Kazumi Horiguchi, Susumu Sekine, Dai Kitagawa, Nobuaki Funata, Masakazu Toi, Kenichi Sugihara, Katsumasa Kuroi
Pages: 273-278
Published online on: 01 August 2009

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Article

Cancerous, but not stromal, thrombospondin-2 contributes prognosis in pulmonary adenocarcinoma

Tsuyoshi Chijiwa, Yoshiyuki Abe, Yoshimasa Inoue, Hozumi Matsumoto, Kenji Kawai, Masahiro Matsuyama, Noriyuki Miyazaki, Hiroshi Inoue, Masaya Mukai, Yoshito Ueyama, Masato Nakamura
Pages: 279-283
Published online on: 01 August 2009

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Article

Angiogenesis in cervical cancer is mediated by HeLa metabolites through endothelial cell tissue kallikrein

Strinivasen Naidoo, Deshandra Munsamy Raidoo
Pages: 285-293
Published online on: 01 August 2009

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Article

Immunoexpression of inhibitors of apoptosis proteins and their antagonist SMAC/DIABLO in colorectal carcinoma: Correlation with apoptotic index, cellular proliferation and prognosis

Flávio De Oliveira Lima, Henrique De Oliveira Costa, Luis Fernando Mesias Barrezueta, Celina Tizuko Fujiyama Oshima, José Antonio Silva, Thiago Simão Gomes, Nathanael Pinheiro, Ricardo Artigiani Neto, Marcello Franco
Pages: 295-303
Published online on: 01 August 2009

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Article

Chromosomal imbalances, 11q21 rearrangement and MECT1-MAML2 fusion transcript in mucoepidermoid carcinomas of the salivary gland

Irmgard Verdorfer, Andre Fehr, Jörn Bullerdiek, Nina Scholz, Andrea Brunner, Jens Krugmann, Martina Hager, Heike Haufe, Gregor Mikuz, Arne Scholtz
Pages: 305-311
Published online on: 01 August 2009

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Article

The regulatory effect of the p38 signaling pathway on valdecoxib-induced apoptosis of the Eca109 cell line

Shu-Xia Liu, Yu-Jun Zhang, Hui-Fang Guo, Jun Hao, Qing-Juan Liu, Jun-Ru Liu, Jian-Wen Guo, Jiang-Hui Liu, Lian-Fu Zuo
Pages: 313-319
Published online on: 01 August 2009

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Article

Paclitaxel encapsulated in cationic liposomes: A new option for neovascular targeting for the treatment of prostate cancer

Christian Bode, Lutz Trojan, Christel Weiss, Bettina Kraenzlin, Uwe Michaelis, Michael Teifel, Peter Alken, Maurice Stephan Michel
Pages: 321-326
Published online on: 01 August 2009

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Article

Androgen deprivation therapy regulation of β1C integrin expression in prostate cancer

Paolo Fuzio, Giuseppe Lucarelli, Elda Perlino, Michele Battaglia, Carlo Bettocchi, Francesco Paolo Selvaggi, Pasquale Ditonno
Pages: 327-335
Published online on: 01 August 2009

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Article

Enhancement of anti-tumor immunity by high levels of Th1 and Th17 with a combination of dendritic cell fusion hybrids and regulatory T cell depletion in pancreatic cancer

Masashi Yamamoto, Takashi Kamigaki, Kimihiro Yamashita, Yuichi Hori, Hiroshi Hasegawa, Daisuke Kuroda, Hiroaki Moriyama, Masao Nagata, Yonson Ku, Yoshikazu Kuroda
Pages: 337-343
Published online on: 01 August 2009

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Article

Survival after cytotoxic chemotherapy in patients with advanced hormone-resistant prostate cancer: A phase II study

George P. Stathopoulos, John Koutantos, Michael M. Vaslamatzis, Athanasios Athanasiadis, George Papadopoulos, G. Labrodimou, John Stathopoulos, Sotiris Rigatos
Pages: 345-348
Published online on: 01 August 2009

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Article

Growth inhibitory activity of ethanol extracts of Chinese and Brazilian propolis in four human colon carcinoma cell lines

Masashi Ishihara, Kuniko Naoi, Masanari Hashita, Yoshinori Itoh, Masumi Suzui
Pages: 349-354
Published online on: 01 August 2009

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Article Open Access

Synergistic inhibitory effect of gemcitabine and angiotensin type-1 receptor blocker, losartan, on murine pancreatic tumor growth via anti-angiogenic activities

Ryuichi Noguchi, Hitoshi Yoshiji, Yasuhide Ikenaka, Tadashi Namisaki, Mitsuteru Kitade, Kosuke Kaji, Junichi Yoshii, Koji Yanase, Masaharu Yamazaki, Tatsuhiro Tsujimoto, Hideto Kawaratani, Hiroshi Fukui
Pages: 355-360
Published online on: 01 August 2009

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Article

Tubulin inhibitor AEZS 112 inhibits the growth of experimental human ovarian and endometrial cancers irrespective of caspase inhibition

Jörg B. Engel, Tanja Schönhals, Claudia Weidler, Sebastian Häusler, Mathias Krockenberger, Lorenz Rieger, Johannes Dietl, Jörg Wischhusen, Arnd Honig
Pages: 361-367
Published online on: 01 August 2009

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Article

Alterations of glycosaminoglycan disaccharide content and composition in colorectal cancer: Structural and expressional studies

Dimitrios Kalathas, Dimitrios A. Theocharis, Dimitrios Bounias, Dora Kyriakopoulou, Nikoletta Papageorgakopoulou, Michael S. Stavropoulos, Demitrios H. Vynios
Pages: 369-375
Published online on: 01 August 2009

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Article

Serenoa repens induces growth arrest and apoptosis of human multiple myeloma cells via inactivation of STAT 3 signaling

Yuqin Che, Shuai Hou, Zhiwei Kang, Qiao Lin
Pages: 377-383
Published online on: 01 August 2009

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Article

The effects of N-acetyl cysteine, buthionine sulfoximine, diethyldithiocarbamate or 3-amino-1,2,4-triazole on antimycin A-treated Calu-6 lung cells in relation to cell growth, reactive oxygen species and glutathione

Yong Hwan Han, Woo Hyun Park
Pages: 385-391
Published online on: 01 August 2009

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Article

Small polydispersed circular DNA contains strains of mobile genetic elements and occurs more frequently in permanent cell lines of malignant tumors than in normal lymphocytes

Hannelore Schmidt, Helge Taubert, Heidemarie Lange, Karen Kriese, Wolfgang Daniel Schmitt, Steve Hoffmann, Frank Bartel, Steffen Hauptmann
Pages: 393-400
Published online on: 01 August 2009

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Article

Identification of two new serum protein profiles for renal cell carcinoma

Judith Y.M.N. Engwegen, Niven Mehra, John B.A.G. Haanen, Jan H.M. Schellens, Emile E. Voest, Jos H. Beijnen
Pages: 401-408
Published online on: 01 August 2009

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Article

Divergent effects of taurolidine as potential anti-neoplastic agent: Inhibition of bladder carcinoma cells in vitro and promotion of bladder tumor in vivo

Claudia Abramjuk, Michael Bueschges, Jörg Schnorr, Klaus Jung, Andrea Staack, Michael Lein
Pages: 409-414
Published online on: 01 August 2009

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Article

Stereotactic radiotherapy in recurrent gynecological cancer: A case series

Francesco Deodato, Gabriella Macchia, Luca Grimaldi, Gabriella Ferrandina, Domenica Lorusso, Vanda Salutari, Savino Cilla, Vincenzo Valentini, Numa Cellini, Angelo Piermattei, Giovanni Scambia, Alessio Giuseppe Morganti
Pages: 415-419
Published online on: 01 August 2009

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Article

Prognostic index reflecting genetic alteration related to disease-free time for gastric cancer patient

Mijung Kim, Sun Young Rha
Pages: 421-431
Published online on: 01 August 2009

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Review Open Access

Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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Article Open Access

TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Review Open Access

Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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Article Open Access

High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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