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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2009 Volume 22 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Epigenetic alterations associated with cholangiocarcinoma (Review)

Hajime Isomoto
Pages: 227-232
Published online on: 01 August 2009

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Review

Molecular pathogenesis of endometriosis-associated clear cell carcinoma of the ovary (Review)

Hiroshi Kobayashi, Hirotaka Kajiwara, Seiji Kanayama, Yoshihiko Yamada, Naoto Furukawa, Taketoshi Noguchi, Shoji Haruta, Shozo Yoshida, Mariko Sakata, Toshiyuki Sado, Hidekazu Oi
Pages: 233-240
Published online on: 01 August 2009

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Article Open Access

Antitumor activity of bevacizumab in combination with capecitabine and oxaliplatin in human colorectal cancer xenograft models

Mieko Yanagisawa, Kaori Fujimoto-Ouchi, Keigo Yorozu, Yoriko Yamashita, Kazushige Mori
Pages: 241-247
Published online on: 01 August 2009

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Article

hnRNP U interacts with the c-Myc-Max complex on the E-box promoter region inducing the ornithine decarboxylase gene

Yoichiro Matsuoka, Norihisa Uehara, Airo Tsubura
Pages: 249-255
Published online on: 01 August 2009

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Article

Proliferation of estrogen-responsive mouse tumor cell line B-1F stimulated by Saiboku-to, but inhibited by Scutellaria baicalensis, a component of Saiboku-to

Teruko Murashima, Megumi Yamasaki, Yoshio Nishizawa, Hiroshi Katayama, Yumiko Tanigaki, Yoshiko Saeki, Kimura Shojiro, Yasuko Nishizawa
Pages: 257-264
Published online on: 01 August 2009

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Article

Differences in expression between transcripts using alternative promoters of hMLH1 gene and their correlation with microsatellite instability

Ryosuke Takahashi, Keiichi Nagai
Pages: 265-271
Published online on: 01 August 2009

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Article

A low number of tumor-infiltrating FOXP3-positive cells during primary systemic chemotherapy correlates with favorable anti-tumor response in patients with breast cancer

Tomoyuki Aruga, Eiji Suzuki, Shigehira Saji, Shin-Ichirou Horiguchi, Kazumi Horiguchi, Susumu Sekine, Dai Kitagawa, Nobuaki Funata, Masakazu Toi, Kenichi Sugihara, Katsumasa Kuroi
Pages: 273-278
Published online on: 01 August 2009

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Article

Cancerous, but not stromal, thrombospondin-2 contributes prognosis in pulmonary adenocarcinoma

Tsuyoshi Chijiwa, Yoshiyuki Abe, Yoshimasa Inoue, Hozumi Matsumoto, Kenji Kawai, Masahiro Matsuyama, Noriyuki Miyazaki, Hiroshi Inoue, Masaya Mukai, Yoshito Ueyama, Masato Nakamura
Pages: 279-283
Published online on: 01 August 2009

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Article

Angiogenesis in cervical cancer is mediated by HeLa metabolites through endothelial cell tissue kallikrein

Strinivasen Naidoo, Deshandra Munsamy Raidoo
Pages: 285-293
Published online on: 01 August 2009

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Article

Immunoexpression of inhibitors of apoptosis proteins and their antagonist SMAC/DIABLO in colorectal carcinoma: Correlation with apoptotic index, cellular proliferation and prognosis

Flávio De Oliveira Lima, Henrique De Oliveira Costa, Luis Fernando Mesias Barrezueta, Celina Tizuko Fujiyama Oshima, José Antonio Silva, Thiago Simão Gomes, Nathanael Pinheiro, Ricardo Artigiani Neto, Marcello Franco
Pages: 295-303
Published online on: 01 August 2009

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Article

Chromosomal imbalances, 11q21 rearrangement and MECT1-MAML2 fusion transcript in mucoepidermoid carcinomas of the salivary gland

Irmgard Verdorfer, Andre Fehr, Jörn Bullerdiek, Nina Scholz, Andrea Brunner, Jens Krugmann, Martina Hager, Heike Haufe, Gregor Mikuz, Arne Scholtz
Pages: 305-311
Published online on: 01 August 2009

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Article

The regulatory effect of the p38 signaling pathway on valdecoxib-induced apoptosis of the Eca109 cell line

Shu-Xia Liu, Yu-Jun Zhang, Hui-Fang Guo, Jun Hao, Qing-Juan Liu, Jun-Ru Liu, Jian-Wen Guo, Jiang-Hui Liu, Lian-Fu Zuo
Pages: 313-319
Published online on: 01 August 2009

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Article

Paclitaxel encapsulated in cationic liposomes: A new option for neovascular targeting for the treatment of prostate cancer

Christian Bode, Lutz Trojan, Christel Weiss, Bettina Kraenzlin, Uwe Michaelis, Michael Teifel, Peter Alken, Maurice Stephan Michel
Pages: 321-326
Published online on: 01 August 2009

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Article

Androgen deprivation therapy regulation of β1C integrin expression in prostate cancer

Paolo Fuzio, Giuseppe Lucarelli, Elda Perlino, Michele Battaglia, Carlo Bettocchi, Francesco Paolo Selvaggi, Pasquale Ditonno
Pages: 327-335
Published online on: 01 August 2009

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Article

Enhancement of anti-tumor immunity by high levels of Th1 and Th17 with a combination of dendritic cell fusion hybrids and regulatory T cell depletion in pancreatic cancer

Masashi Yamamoto, Takashi Kamigaki, Kimihiro Yamashita, Yuichi Hori, Hiroshi Hasegawa, Daisuke Kuroda, Hiroaki Moriyama, Masao Nagata, Yonson Ku, Yoshikazu Kuroda
Pages: 337-343
Published online on: 01 August 2009

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Article

Survival after cytotoxic chemotherapy in patients with advanced hormone-resistant prostate cancer: A phase II study

George P. Stathopoulos, John Koutantos, Michael M. Vaslamatzis, Athanasios Athanasiadis, George Papadopoulos, G. Labrodimou, John Stathopoulos, Sotiris Rigatos
Pages: 345-348
Published online on: 01 August 2009

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Article

Growth inhibitory activity of ethanol extracts of Chinese and Brazilian propolis in four human colon carcinoma cell lines

Masashi Ishihara, Kuniko Naoi, Masanari Hashita, Yoshinori Itoh, Masumi Suzui
Pages: 349-354
Published online on: 01 August 2009

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Article Open Access

Synergistic inhibitory effect of gemcitabine and angiotensin type-1 receptor blocker, losartan, on murine pancreatic tumor growth via anti-angiogenic activities

Ryuichi Noguchi, Hitoshi Yoshiji, Yasuhide Ikenaka, Tadashi Namisaki, Mitsuteru Kitade, Kosuke Kaji, Junichi Yoshii, Koji Yanase, Masaharu Yamazaki, Tatsuhiro Tsujimoto, Hideto Kawaratani, Hiroshi Fukui
Pages: 355-360
Published online on: 01 August 2009

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Article

Tubulin inhibitor AEZS 112 inhibits the growth of experimental human ovarian and endometrial cancers irrespective of caspase inhibition

Jörg B. Engel, Tanja Schönhals, Claudia Weidler, Sebastian Häusler, Mathias Krockenberger, Lorenz Rieger, Johannes Dietl, Jörg Wischhusen, Arnd Honig
Pages: 361-367
Published online on: 01 August 2009

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Article

Alterations of glycosaminoglycan disaccharide content and composition in colorectal cancer: Structural and expressional studies

Dimitrios Kalathas, Dimitrios A. Theocharis, Dimitrios Bounias, Dora Kyriakopoulou, Nikoletta Papageorgakopoulou, Michael S. Stavropoulos, Demitrios H. Vynios
Pages: 369-375
Published online on: 01 August 2009

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Article

Serenoa repens induces growth arrest and apoptosis of human multiple myeloma cells via inactivation of STAT 3 signaling

Yuqin Che, Shuai Hou, Zhiwei Kang, Qiao Lin
Pages: 377-383
Published online on: 01 August 2009

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Article

The effects of N-acetyl cysteine, buthionine sulfoximine, diethyldithiocarbamate or 3-amino-1,2,4-triazole on antimycin A-treated Calu-6 lung cells in relation to cell growth, reactive oxygen species and glutathione

Yong Hwan Han, Woo Hyun Park
Pages: 385-391
Published online on: 01 August 2009

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Article

Small polydispersed circular DNA contains strains of mobile genetic elements and occurs more frequently in permanent cell lines of malignant tumors than in normal lymphocytes

Hannelore Schmidt, Helge Taubert, Heidemarie Lange, Karen Kriese, Wolfgang Daniel Schmitt, Steve Hoffmann, Frank Bartel, Steffen Hauptmann
Pages: 393-400
Published online on: 01 August 2009

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Article

Identification of two new serum protein profiles for renal cell carcinoma

Judith Y.M.N. Engwegen, Niven Mehra, John B.A.G. Haanen, Jan H.M. Schellens, Emile E. Voest, Jos H. Beijnen
Pages: 401-408
Published online on: 01 August 2009

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Article

Divergent effects of taurolidine as potential anti-neoplastic agent: Inhibition of bladder carcinoma cells in vitro and promotion of bladder tumor in vivo

Claudia Abramjuk, Michael Bueschges, Jörg Schnorr, Klaus Jung, Andrea Staack, Michael Lein
Pages: 409-414
Published online on: 01 August 2009

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Article

Stereotactic radiotherapy in recurrent gynecological cancer: A case series

Francesco Deodato, Gabriella Macchia, Luca Grimaldi, Gabriella Ferrandina, Domenica Lorusso, Vanda Salutari, Savino Cilla, Vincenzo Valentini, Numa Cellini, Angelo Piermattei, Giovanni Scambia, Alessio Giuseppe Morganti
Pages: 415-419
Published online on: 01 August 2009

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Article

Prognostic index reflecting genetic alteration related to disease-free time for gastric cancer patient

Mijung Kim, Sun Young Rha
Pages: 421-431
Published online on: 01 August 2009

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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