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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2010 Volume 24 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Recommendations for ‘Adequate Evaluation of Hormone Receptors’ A report of the task force of the Japanese Breast Cancer Society

Shinobu Umemura, Masafumi Kurosumi, Takuya Moriya, Tetsunari Oyama, Kohji Arihiro, Hiroko Yamashita, Yoshihisa Umekita, Yoshifumi Komoike, Chikako Shimizu, Hisaki Fukushima, Hiroshi Kajiwara, Futoshi Akiyama
Pages: 299-304
Published online on: 01 August 2010

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Article

Neutrophil gelatinase-associated lipocalin immunoexpression in renal tumors: Correlation with histotype and histological grade

Valeria Barresi, Antonio Ieni, Davide Bolignano, Carlo Magno, Michele Buemi, Gaetano Barresi
Pages: 305-310
Published online on: 01 August 2010

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Article

Discoidin domain receptor 1 is associated with poor prognosis of non-small cell lung carcinomas

Sun Ho Yang, Hyun Ah Baek, Ho Jin Lee, Ho Sung Park, Kyu Yun Jang, Myoung Jae Kang, Dong Geun Lee, Yong Chul Lee, Woo Sung Moon, Myoung Ja Chung
Pages: 311-319
Published online on: 01 August 2010

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Article

Expression of 53BP1 as a cisplatin-resistant marker in patients with lung adenocarcinomas

Tan-Chen Lai, Kuan-Chih Chow, Tze-Yi Lin, I-Ping Chiang, Hsin-Yuan Fang, Chih-Yi Chen, Shu-Peng Ho
Pages: 321-328
Published online on: 01 August 2010

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Article

A novel MEK1/2 inhibitor induces G1/S cell cycle arrest in human fibrosarcoma cells

Taka-Aki Matsui, Hiroaki Murata, Yoshihiro Sowa, Tomoya Sakabe, Kazutaka Koto, Naoyuki Horie, Yoshiro Tsuji, Toshiyuki Sakai, Toshikazu Kubo
Pages: 329-333
Published online on: 01 August 2010

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Article

Arsenic trioxide inhibits DNA methyltransferase and restores expression of methylation-silenced CDKN2B/CDKN2A genes in human hematologic malignant cells

Hai-Ying Fu, Jian-Zhen Shen, Yong Wu, Song-Fei Shen, Hua-Rong Zhou, Li-Ping Fan
Pages: 335-343
Published online on: 01 August 2010

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Article

Immunohistochemical features of CD133 expression: Association with resistance to chemoradiotherapy in rectal cancer

Susumu Saigusa, Koji Tanaka, Yuji Toiyama, Takeshi Yokoe, Yoshinaga Okugawa, Aya Kawamoto, Hiromi Yasuda, Yuki Morimoto, Hiroyuki Fujikawa, Yasuhiro Inoue, Chikao Miki, Masato Kusunoki
Pages: 345-350
Published online on: 01 August 2010

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Article

Induction of cell growth arrest and apoptotic cell death in human breast cancer MCF-7 cells by the COX-1 inhibitor FR122047

Hyo-Soon Jeong, Jung-Hyun Kim, Hye Yeon Choi, Eung-Ryoung Lee, Ssang-Goo Cho
Pages: 351-356
Published online on: 01 August 2010

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Article

Dehydroepiandrosterone intake protects against 7,12-dimethylbenz(a)anthracene-induced mammary tumor development in the obese Zucker rat model

Reza Hakkak, Saied Shaaf, Chan-Hee Jo, Stewart MacLeod, Soheila Korourian
Pages: 357-362
Published online on: 01 August 2010

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Article

Notch-4 contributes to the metastasis of salivary adenoid cystic carcinoma

Lin-Can Ding, Lin She, Da-Li Zheng, Qing-Ling Huang, Jin-Feng Wang, Fei-Fei Zheng, You-Guang Lu
Pages: 363-368
Published online on: 01 August 2010

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Article Open Access

Comparative expressed sequence hybridization detects recurrent patterns of altered sequence expression in oral squamous cell carcinoma

Snjezana Janjetovic, Carsten Sticht, Karl Knoepfle, Stefan Joos, Christof Hofele, Peter Lichter, Kolja Freier
Pages: 369-374
Published online on: 01 August 2010

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Article

Periplocin from Cortex periplocae inhibits cell growth and down-regulates survivin and c-myc expression in colon cancer in vitro and in vivo via β-catenin/TCF signaling

Lianmei Zhao, Baoen Shan, Yanyan Du, Mingxia Wang, Lihua Liu, Feng-Zhi Ren
Pages: 375-383
Published online on: 01 August 2010

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Article

Prognostic significance and clinical importance of estrogen receptor α and β in human endometrioid adenocarcinomas

Ioannis Mylonas
Pages: 385-393
Published online on: 01 August 2010

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Article

Time-dependently expressed markers and the characterization for premature senescence induced by ionizing radiation in MCF7

Bong Cho Kim, Na-Kyung Han, Hae-Ok Byun, Seung-Soo Kim, Eun-Kyung Ahn, In-Sun Chu, Sun-Hee Leem, Cheol-Koo Lee, Jae-Seon Lee
Pages: 395-403
Published online on: 01 August 2010

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Article

Infiltration of thymidine phosphorylase-positive macrophages is closely associated with tumor angiogenesis and survival in intestinal type gastric cancer

Akihiko Kawahara, Satoshi Hattori, Jun Akiba, Kazutaka Nakashima, Tomoki Taira, Kosuke Watari, Fumihito Hosoi, Manami Uba, Yuji Basaki, Kikuo Koufuji, Kazuo Shirouzu, Shin-Ichi Akiyama, Michihiko Kuwano, Masayoshi Kage, Mayumi Ono
Pages: 405-415
Published online on: 01 August 2010

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Article

Interstitial high-dose-rate brachytherapy after breast conserving surgery

Antonio Rulli, Francesco Barberini, Michele Scialpi, Luciano Izzo, Ilaria D'Angeli, Stefania Gori, Angelo Sidoni, Fabio Rondelli, Giuseppe Noya, Cinzia Aristei
Pages: 417-422
Published online on: 01 August 2010

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Article

Aberrant promoter methylation of WIF-1 and SFRP1, 2, 4 genes in mesothelioma

Hidekazu Kohno, Vishwa Jeet Amatya, Yukio Takeshima, Kei Kushitani, Noboru Hattori, Nobuoki Kohno, Kouki Inai
Pages: 423-431
Published online on: 01 August 2010

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Article

Evaluation of the novel gene Rabl3 in the regulation of proliferation and motility in human cancer cells

Qi Li, Li Wang, Linge Zeng, Yingmei Zhang, Kangqi Li, Peng Jin, Bingnan Su, Lu Wang
Pages: 433-440
Published online on: 01 August 2010

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Article

Gastrin-releasing peptide promotes the growth of HepG2 cells via EGFR-independent ERK1/2 activation

Xinqiu Li, Yunfu Lv, Aihua Yuan, Shanyong Yi, Yong Ma, Zongfang Li
Pages: 441-448
Published online on: 01 August 2010

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Article

Allyl isothiocyanate triggers G2/M phase arrest and apoptosis in human brain malignant glioma GBM 8401 cells through a mitochondria-dependent pathway

Nian-Gu Chen, Kuan-Tin Chen, Chi-Cheng Lu, Yu-Hsuan Lan, Cheng-Hung Lai, Yang-Tsung Chung, Jai-Sing Yang, Yung-Chang Lin
Pages: 449-455
Published online on: 01 August 2010

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Article

Monoclonal antibodies targeting basic fibroblast growth factor inhibit the growth of B16 melanoma in vivo and in vitro

Dan Li, Hong Wang, Jun-Jian Xiang, Ning Deng, Pan-Pan Wang, Yan-Li Kang, Jun Tao, Meng Xu
Pages: 457-463
Published online on: 01 August 2010

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Article

Expression profile of RhoGDI2 in lung cancers and role of RhoGDI2 in lung cancer metastasis

Huiyan Niu, Hui Li, Can Xu, Ping He
Pages: 465-471
Published online on: 01 August 2010

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Article

Ethanol extract of Lycoris radiata induces cell death in B16F10 melanoma via p38-mediated AP-1 activation

Minsik Son, Aeyung Kim, Jaewoo Lee, Chul-Hong Park, Jin-Chul Heo, Hyun-Jin Lee, Sang-Han Lee
Pages: 473-478
Published online on: 01 August 2010

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Article

Decreased expression of S100A6 in oral squamous cell carcinoma

Xiao Yang, Kui-Jie Wei, Lei Zhang, Hong-Ya Pan, Dong-Xia Ye, Lai-Ping Zhong, Zhi-Yuan Zhang
Pages: 479-488
Published online on: 01 August 2010

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Article

A breast cancer prognostic signature predicts clinical outcomes in multiple tumor types

Ying-Wooi Wan, Yong Qian, Shruti Rathnagiriswaran, Vincent Castranova, Nancy Lan Guo
Pages: 489-494
Published online on: 01 August 2010

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Article

Identification of Galectin-1 as a novel biomarker in nasopharyngeal carcinoma by proteomic analysis

Can-E Tang, Tan Tan, Cui Li, Zhu-Chu Chen, Lin Ruan, Hong-Han Wang, Tao Su, Peng-Fei Zhang, Zhi-Qiang Xiao
Pages: 495-500
Published online on: 01 August 2010

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Article Open Access

Possible involvement of stem-like populations with elevated ALDH1 in sarcomas for chemotherapeutic drug resistance

Kanya Honoki, Hiromasa Fujii, Atsushi Kubo, Akira Kido, Toshio Mori, Yasuhito Tanaka, Toshifumi Tsujiuchi
Pages: 501-505
Published online on: 01 August 2010

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Article

Sunitinib in patients with metastatic renal cell carcinoma: Birmingham experience

Jawaher Ansari, Arfeen Fatima, Kieran Fernando, Stuart Collins, Nicholas D. James, Emilio Porfiri
Pages: 507-510
Published online on: 01 August 2010

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Article

Clinicopathological, but not socio-demographic factors affect the prognosis in cervical carcinoma

Radha Munagala, Shesh N. Rai, Selvaluxmy Ganesharajah, Nagarajan Bala, Ramesh C. Gupta
Pages: 511-520
Published online on: 01 August 2010

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Article

Postoperative serum α-fetoprotein level is a useful predictor of recurrence after hepatectomy for hepatocellular carcinoma

Daisuke Nobuoka, Yuichiro Kato, Naoto Gotohda, Shinichiro Takahashi, Toshio Nakagohri, Masaru Konishi, Taira Kinoshita, Tetsuya Nakatsura
Pages: 521-528
Published online on: 01 August 2010

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Article

Pharmacokinetics of S-1 and CYP2A6 genotype in Japanese patients with advanced cancer

Takashi Hirose, Ken-Ichi Fujita, Kazuko Nishimura, Hiroo Ishida, Keishi Yamashita, Yu Sunakawa, Keiko Mizuno, Keisuke Miwa, Fumio Nagashima, Yusuke Tanigawara, Mitsuru Adachi, Yasutsuna Sasaki
Pages: 529-536
Published online on: 01 August 2010

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Article

Cytoplasmic expression of CD133 is an important risk factor for overall survival in hepatocellular carcinoma

Ayami Sasaki, Toshiya Kamiyama, Hideki Yokoo, Kazuaki Nakanishi, Kanako Kubota, Hironori Haga, Michiaki Matsushita, Michitaka Ozaki, Yoshihiro Matsuno, Satoru Todo
Pages: 537-546
Published online on: 01 August 2010

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Article

AF1q enhancement of γ irradiation-induced apoptosis by up-regulation of BAD expression via NF-κB in human squamous carcinoma A431 cells

Ngai Na Co, Wing Pui Tsang, Tsun Yee Tsang, Chi Lam Au Yeung, Pak Lun Yau, Siu Kai Kong, Tim Tak Kwok
Pages: 547-554
Published online on: 01 August 2010

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Article

Tumor suppressor gene alterations of spontaneously malignant transformed cells from human embryonic muscle in vitro

Xianyao Wang, Wenyu Li, Jiakun Zheng, Qiang Chen, Haiying Zou, Lian Ma, Guangyu Lin, Tianhua Huang, Ge Huang, Liye Yang
Pages: 555-561
Published online on: 01 August 2010

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Article

Inhibition of catechol-Ο-methyltransferase activity in human breast cancer cells enhances the biological effect of the green tea polyphenol (-)-EGCG

Kristin Landis-Piwowar, Di Chen, Tak Hang Chan, Q. Ping Dou
Pages: 563-569
Published online on: 01 August 2010

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Article

Integrative genomic analyses on Ikaros and its expression related to solid cancer prognosis

Liming Yang, Yuming Luo, Jifu Wei
Pages: 571-577
Published online on: 01 August 2010

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Article

PPARγ polymorphisms and cancer risk: A meta-analysis involving 32,138 subjects

Wei Xu, Yan Li, Xueli Wang, Bo Chen, Shan Liu, Yan Wang, Weihong Zhao, Jianqing Wu
Pages: 579-585
Published online on: 01 August 2010

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
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Expression of Concern Open Access

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