Journal Articles

Review

Alterations in molecular pathways of diffusely infiltrating glial neoplasms: application to tumor classification and anti-tumor therapy (Review)

Stephen B. Hunter, Daniel J. Brat, Jeffrey J. Olson, Andreas Von Deimling, Wei Zhou, Erwin G. Van Meir

Pages: 857-869 Published online on: 01 October 2003
Article

Genotypic analysis of esophageal squamous cell carcinoma by molecular cytogenetics and real-time quantitative polymerase chain reaction

Chueh-Chuan Yen, Yann-Jang Chen, Kai-Hsi Lu, Jiun-Yi Hsia, Jung-Ta Chen, Cheng-Po Hu, Po-Min Chen, Jin-Hwang Liu, Tzeon-Jye Chiou, Wei-Shu Wang, Muh-Hwa Yang, Ta-Chung Chao, Chi-Hung Lin

Pages: 871-881 Published online on: 01 October 2003
Article

Cloning and chromosomal characterization of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 gene (PFKFB3, iPFK2)

Ulrich Mahlknecht, Jason Chesney, Dieter Hoelzer, Richard Bucala

Pages: 883-891 Published online on: 01 October 2003
Article

Characterisation and predictive value of epidermal growth factor receptor status using quantitative real-time PCR combined with immunohistochemistry on non-small cell lung cancer specimens

Wolfgang Hilbe, Margit Dlaska, Stephan Dirnhofer, Hans-Christoph Duba, Wolfgang Eisterer, Frieda Oberwasserlechner, Andreas Mildner, Thomas Schmid, Karlheinz Ammann, Josef Thaler, Ewald Wöll

Pages: 893-899 Published online on: 01 October 2003
Article

Clinical significance of thrombospondin-1 expression in relation to vascular endothelial growth factor and interleukin-10 expression at the deepest invasive tumor site of advanced colorectal carcinoma

Eijiro Kaio, Shinji Tanaka, Shiro Oka, Toru Hiyama, Yasuhiko Kitadai, Ken Haruma, Kazuaki Chayama

Pages: 901-911 Published online on: 01 October 2003
Article

Selection of surrogate marker genes in primary central nervous system lymphomas for radio-chemotherapy by DNA array analysis of gene expression profiles

Ryuya Yamanaka, Shigeru Akutagawa, Fumiko Taguchi, Naoki Yajima, Naoto Tsuchiya, Takeo Uzuka, Ken Morii, Hideaki Takahashi, Ryuichi Tanaka, Nagahiro Saijo, Kazuto Nishio

Pages: 913-923 Published online on: 01 October 2003
Article

Immortalization of bone marrow-derived human mesenchymal stem cells by removable simian virus 40T antigen gene: Analysis of the ability to support expansion of cord blood hematopoietic progenitor cells

Keisuke Nishioka, Yoshihiro Fujimori, Tomoko Hashimoto-Tamaoki, Shunro Kai, Huiying Qiu, Naoya Kobayashi, Noriaki Tanaka, Karen A. Westerman, Philippe Leboulch, Hiroshi Hara

Pages: 925-932 Published online on: 01 October 2003
Article

Difference in gene expression profile in breast epithelial cells from women with different reproductive history

Shanchun Guo, Irma H. Russo, Jose Russo

Pages: 933-941 Published online on: 01 October 2003
Article

Tetraarsenic oxide induces apoptosis in U937 leukemic cells through a reactive oxygen species-dependent pathway

In-Chul Park, Myung-Jin Park, Sang-Hyeok Woo, Hyung-Chahn Lee, Sungkwan An, Ho-Shin Gwak, Seung-Hoon Lee, Seok-Il Hong, Ill-Ju Bae, Kang Moon Seo, Chang Hun Rhee

Pages: 943-948 Published online on: 01 October 2003
Article

Increased survival and decreased tumor size due to intratumoral injection of ethanol followed by administration of immature dendritic cells

Teru Kumagi, S. M. Fazle Akbar, Norio Horiike, Morikazu Onji

Pages: 949-955 Published online on: 01 October 2003
Article

A MEK inhibitor (U0126) prolongs survival in nude mice bearing human gallbladder cancer cells with K-ras mutation: Analysis in a novel orthotopic inoculation model

Hideki Horiuchi, Hitoshi Kawamata, Takahiro Fujimori, Yoshikazu Kuroda

Pages: 957-963 Published online on: 01 October 2003
Article

Differential chemokine, chemokine receptor, cytokine and cytokine receptor expression in pulmonary adenocarcinoma: Diffuse down-regulation is associated with immune evasion and brain metastasis

Koichi Ohshima, Makoto Hamasaki, Yoshifumi Makimoto, Satoshi Yoneda, Akira Fujii, Yasushi Takamatsu, Manabu Nakashima, Takeshi Watanabe, Katunobu Kawahara, Masahiro Kikuchi, Takayuki Shirakusa

Pages: 965-973 Published online on: 01 October 2003
Article

Ruta 6 selectively induces cell death in brain cancer cells but proliferation in normal peripheral blood lymphocytes: A novel treatment for human brain cancer

Sen Pathak, Asha S. Multani, Pratip Banerji, Prasanta Banerji

Pages: 975-982 Published online on: 01 October 2003
Article

Macro-microscopic fluorescence of human bladder cancer using hypericin fluorescence cystoscopy and laser confocal microscopy

Malini Olivo, Weber Lau, Vanaja Manivasager, Puay Hoon Tan, Khee Chee Soo, Christopher Cheng

Pages: 983-990 Published online on: 01 October 2003
Article

Analysis of the structural integrity of the TAP2 gene in renal cell carcinoma

Isabelle Hodson, Michaela Bock, Ulrike Ritz, Walburgis Brenner, Christoph Huber, Barbara Seliger

Pages: 991-999 Published online on: 01 October 2003
Article

Correlation between protein expression and epigenetic and mutation changes of Wnt pathway-related genes in oral cancer

Kun-Tu Yeh, Jan-Gowth Chang, Ting-Hsu Lin, Yu-Fen Wang, Jan-Yi Chang, Mu-Chin Shih, Cheng-Chieh Lin

Pages: 1001-1007 Published online on: 01 October 2003
Article

Differences in loss of p16INK4 protein expression by promoter methylation between left- and right-sided primary colorectal carcinomas

Regine Schneider-Stock, Carsten Boltze, Brigitte Peters, Tino Höpfner, Frank Meyer, Hans Lippert, Albert Roessner

Pages: 1009-1013 Published online on: 01 October 2003
Article

The pro-apoptotic FAS-associated factor 1 is specifically reduced in human gastric carcinomas

Marina Bjørling-Poulsen, Gerhard Seitz, Barbara Guerra, Olaf-Georg Issinger

Pages: 1015-1023 Published online on: 01 October 2003
Article

Immunostaining and RT-PCR: different approaches to search for RET rearrangements in patients with papillary thyroid carcinoma

Sofia Rebelo, Rita Domingues, Ana Luisa Catarino, Evelina Mendonça, Jorge Rosa Santos, Luis Sobrinho, Maria João Bugalho

Pages: 1025-1032 Published online on: 01 October 2003
Article

Chronic hypoxia protects against γ-irradiation-induced apoptosis by inducing bcl-2 up-regulation and inhibiting mitochondrial translocation and conformational change of bax protein

Olivier Cuisnier, Raphael Serduc, Jean-Pierre Lavieille, Michel Longuet, Emile Reyt, Catherine Riva

Pages: 1033-1041 Published online on: 01 October 2003
Article

Over-expression of bone sialoprotein enhances bone metastasis of human breast cancer cells in a mouse model

Jian-Hua Zhang, Jean Tang, Jie Wang, Wenli Ma, Wenling Zheng, Toshiyuki Yoneda, Jake Chen

Pages: 1043-1048 Published online on: 01 October 2003
Article

Detection of cadherin-6 mRNA by nested RT-PCR as a potential marker for circulating cancer cells in renal cell carcinoma

Toru Shimazui, Kazuhiro Yoshikawa, Hirotsugu Uemura, Risa Kawamoto, Koji Kawai, Katsunori Uchida, Yoshihiko Hirao, Shinsuke Saga, Hideyuki Akaza

Pages: 1049-1054 Published online on: 01 October 2003
Review

Potential antitumor effects of statins (Review)

Marek Jakobisiak, Jakub Golab

Pages: 1055-1069 Published online on: 01 October 2003
Article

Acquisition of drug resistance by constitutive suppression of NF-κB in ras-transformed NIH3T3 mouse fibroblasts

Tsukasa Sakaida, Yasuo Iwadate, Sachi Yamaji, Masae Uehara, Asao Noda, Masaki Takiguchi, Akira Yamaura, Takaki Hiwasa

Pages: 1071-1077 Published online on: 01 October 2003
Article

Enhancement of cisplatin-induced cytotoxicity by ROCK inhibitor through suppression of focal adhesion kinase-independent mechanism in lung carcinoma cells

Tadashi Igishi, Masaaki Mikami, Kaori Murakami, Shingo Matsumoto, Yasushi Shigeoka, Hirofumi Nakanishi, Kazuhito Yasuda, J. Silvio Gutkind, Yutaka Hitsuda, Eiji Shimizu

Pages: 1079-1085 Published online on: 01 October 2003
Article

A novel ginseng saponin metabolite induces apoptosis and down-regulates fibroblast growth factor receptor 3 in myeloma cells

Hyun Ho Choi, Hyun-Soon Jong, Jung-Hyun Park, Seongwon Choi, Jung Weon Lee, Tae-You Kim, Takemi Otsuki, Masayoshi Namba, Yung-Jue Bang

Pages: 1087-1093 Published online on: 01 October 2003
Review

The androgen receptor in hormone-refractory prostate cancer: Relevance of different mechanisms of androgen receptor signaling (Review)

M. V. Cronauer, W. A. Schulz, T. Burchardt, A. G. Anastasiadis, A. De la Taille, R. Ackermann, M. Burchardt

Pages: 1095-1102 Published online on: 01 October 2003
Article

Pre- and post-operative adjuvant chemotherapy in colorectal cancer

Hiroharu Isomoto, Masao Tomita, Keizo Sugimachi, Michio Ogawa, Kazutaka Yamada, Tohru Nakagoe, Masaki Mori, Sadamu Takano, Teruo Kakegawa

Pages: 1103-1108 Published online on: 01 October 2003
Article

Suppression of cell migration in ovarian cancer cells mediated by PTEN overexpression

Yasushi Saga, Hiroaki Mizukami, Yuji Takei, Keiya Ozawa, Mitsuaki Suzuki

Pages: 1109-1113 Published online on: 01 October 2003
Article

A new prognostic scoring system involving des-γ-carboxy prothrombin as a useful marker for predicting prognosis in patients with hepatocellular carcinoma

Tomoyuki Kawakita, Katsuya Shiraki, Yutaka Yamanaka, Yumi Yamaguchi, Yukiko Saitou, Naoyuki Enokimura, Norihiko Yamamoto, Hiroshi Okano, Kazushi Sugimoto, Kazumoto Murata, Koichirou Yamakado, Kan Takeda, Takeshi Nakano

Pages: 1115-1120 Published online on: 01 October 2003
Article

Automated real-time PCR to determine K-ras codon 12 mutations in non-small cell lung cancer: Comparison with immunohistochemistry and clinico-pathological features

Wolfgang Hilbe, Margit Dlaska, Hans-Christoph Duba, Stephan Dirnhofer, Wolfgang Eisterer, Frieda Oberwasserlechner, Andreas Mildner, Thomas Schmid, Thomas Kühr, Ewald Wöll

Pages: 1121-1126 Published online on: 01 October 2003
Article

Survival regulation in pancreatic cancer cells by c-Jun

Yoshiyuki Okutomi, Yuji Shino, Fumitake Komoda, Tatsuya Hirano, Takeshi Ishihara, Taketo Yamaguchi, Hiromitsu Saisho, Hiroshi Shirasawa

Pages: 1127-1134 Published online on: 01 October 2003
Article

Expression of HER family receptors and effects of anti-HER2-antibody on human myeloma cell lines

Takemi Otsuki, Junichi Kurebayashi, Sumiko Ohkubo, Masako Uno, Tomohiro Fujii, Haruko Sakaguchi, Tamayo Hatayama, Akiko Takata, Takayuki Tsujioka, Takashi Sugihara, Fuminori Hyodoh

Pages: 1135-1141 Published online on: 01 October 2003
Article

Involvement of p21WAF1/CIP1, pRB, Bax and NF-κB in induction of growth arrest and apoptosis by resveratrol in human lung carcinoma A549 cells

Young-Ae Kim, Won Ho Lee, Tae Hyun Choi, Sook-Hee Rhee, Kun-Young Park, Yung Hyun Choi

Pages: 1143-1149 Published online on: 01 October 2003
Article

Aberrations of p16INK4A, p14ARF and p15INK4B genes in pediatric solid tumors

Kazuko Obana, Hong-Wei Yang, Hui-Ying Piao, Tomohiko Taki, Kohei Hashizume, Ryoji Hanada, Keiko Yamamoto, Yukichi Tanaka, Yasunori Toyoda, Junko Takita, Yoshiaki Tsuchida, Yasuhide Hayashi

Pages: 1151-1157 Published online on: 01 October 2003
Article

Trastuzumab-conjugated boron-containing liposomes for tumor-cell targeting; development and cellular studies

Qichun Wei, Erika Bohl Kullberg, Lars Gedda

Pages: 1159-1165 Published online on: 01 October 2003
Article

Resveratrol suppresses growth of Ishikawa cells through down-regulation of EGF

Masanori Kaneuchi, Masahiro Sasaki, Yuichiro Tanaka, Ritsu Yamamoto, Noriaki Sakuragi, Rajvir Dahiya

Pages: 1167-1172 Published online on: 01 October 2003
Article

Inhibition of lysophosphatidic acid-induced RhoA activation and tumor cell invasion by 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors

Toshiyuki Kusama, Mutsuko Mukai, Masako Ayaki, Fumio Imamura, Masaharu Tatsuta, Yoshirou Matsumoto, Hiroyuki Nakamura, Masahiro Inoue

Pages: 1173-1178 Published online on: 01 October 2003
Article

The recombinant anti-EGF receptor immunotoxin 425(scFv)-ETA' suppresses growth of a highly metastatic pancreatic carcinoma cell line

Daniela Bruell, Michael Stöcker, Michael Huhn, Nicole Redding, Michael Küpper, Petra Schumacher, Antje Paetz, Christiane J. Bruns, Hidde J. Haisma, Rainer Fischer, Ricarda Finnern, Stefan Barth

Pages: 1179-1186 Published online on: 01 October 2003
Article

Oridonin induces growth inhibition and apoptosis of a variety of human cancer cells

Takayuki Ikezoe, Sophie S. Chen, Xian-Jun Tong, David Heber, Hirokuni Taguchi, H. Phillip Koeffler

Pages: 1187-1193 Published online on: 01 October 2003
Article

Enhanced cytotoxicity and nuclear accumulation of doxorubicin-loaded nanospheres in human breast cancer MCF7 cells expressing MRP1

Nasséra Aouali, Hamid Morjani, Aurélie Trussardi, Emilienne Soma, Bruno Giroux, Michel Manfait

Pages: 1195-1201 Published online on: 01 October 2003
Article

PC-SPES decreases proliferation and induces differentiation and apoptosis of human acute myeloid leukemia cells

Takayuki Ikezoe, Sophie Chen, Tsuyako Saito, Hiroya Asou, Taiichi Kyo, Sakae Tanosaki, David Heber, Hirokuni Taguchi, H. Phillip Koeffler

Pages: 1203-1211 Published online on: 01 October 2003
Article

Identification and characterization of TPARM gene in silico

Masuko Katoh, Masaru Katoh

Pages: 1213-1217 Published online on: 01 October 2003
Article

Nuclear texture and chromatin structure in OV1/VCR human multidrug-resistant cell line

Sonia Yatouji, Aurelie Trussardi-Regnier, Chantal Trentesaux, Françoise Liautaud-Roger, Jean Dufer

Pages: 1225-1230 Published online on: 01 October 2003
Article

Role of antioxidant genes for the activity of artesunate against tumor cells

Thomas Efferth, Margaret M. Briehl, Margaret E. Tome

Pages: 1231-1235 Published online on: 01 October 2003
Article

Factors influencing the expression of endogenous reverse transcriptases and viral-like 30 elements in mouse NIH3T3 cells

Theodore Tzavaras, Sofia Eftaxia, Sotiria Tavoulari, Paraskevi Hatzi, Charalambos Angelidis

Pages: 1237-1243 Published online on: 01 October 2003
Article

A3 adenosine receptor agonist potentiates natural killer cell activity

Arie Harish, Gil Hohana, Pnina Fishman, Oshra Arnon, Sara Bar-Yehuda

Pages: 1245-1249 Published online on: 01 October 2003
Journal Cover

Cover Legend PDF

October 2003
Volume 23 Issue 4

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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