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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2004 Volume 25 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Ubiquilin-1 is a novel HASH-1-complexing protein that regulates levels of neuronal bHLH transcription factors in human neuroblastoma cells

Paula Persson, Marie-Thérése Stockhausen, Sven Påhlman, Håkan Axelson
Pages: 1213-1221
Published online on: 01 November 2004

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Article

The ectopeptidases CD10, CD13, CD26, and CD143 are upregulated in gastric cancer

Stacy Carl-McGrath, Uwe Lendeckel, Matthias Ebert, Alexandra-Beatrice Wolter, Albert Roessner, Christoph Röcken
Pages: 1223-1232
Published online on: 01 November 2004

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Article

Detection of S100B, S100A6 and galectin-3 ligands in meningiomas as markers of aggressiveness

Sabine Hancq, Isabelle Salmon, Jacques Brotchi, Hans-Joachim Gabius, Claus W. Heizmann, Robert Kiss, Christine Decaestecker
Pages: 1233-1240
Published online on: 01 November 2004

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Article

Expression of p27 and MAPK proteins involved in all-trans retinoic acid-induced apoptosis and cell cycle arrest in matched primary and metastatic melanoma cells

Hong Zhang, Inger Rosdahl
Pages: 1241-1248
Published online on: 01 November 2004

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Article

The PDZ protein Tip-1 is a gain of function target of the HPV16 E6 oncoprotein

Lynne Hampson, Chenggang Li, Anthony William Oliver, Henry Charles Kitchener, Ian Noel Hampson
Pages: 1249-1256
Published online on: 01 November 2004

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Article

Subcellular localization of MUC1 recognized by a monoclonal antibody MY.1E12 correlates with postsurgical prognosis in differentiated-type gastric carcinomas of stage II and III

Eiji Shinozaki, Shinya Adachi, Junichi Shoda, Toru Kawamoto, Hideo Suzuki, Tatsuro Irimura, Nobuhiro Ohkohchi
Pages: 1257-1265
Published online on: 01 November 2004

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Article

Anti-endostatin monoclonal antibody enhances growth of human hepatocellular carcinoma cells by inhibiting activity of endostatin secreted by the transplanted cells in nude mice

So Tsuboi, Kazuhiro Nouso, Yasuko Tomono, Seishi Nagamori, Ichiro Naito, Tsunakazu Watanabe, Koji Manabe, Hiroyuki Ohmori, Harushige Nakatsukasa, Masahiro Miyazaki, Toshihiro Higashi, Yasushi Shiratori, Masayoshi Namba, Yoshifumi Ninomiya
Pages: 1267-1271
Published online on: 01 November 2004

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Article

Allele-specific methylation analysis on upstream promoter region of H19 by methylation-specific PCR with confronting two-pair primers

Hiromi Sasamoto, Takeshi Nagasaka, Kenji Notohara, Kazuhide Ozaki, Hiroshi Isozaki, Noriaki Tanaka, Nagahide Matsubara
Pages: 1273-1278
Published online on: 01 November 2004

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Article

Genes associated with human hepatocellular carcinoma cell chemosensitivity to 5-fluorouracil plus interferon-α combination chemotherapy

Masaru Moriyama, Yujin Hoshida, Naoya Kato, Motoyuki Otsuka, Haruhiko Yoshida, Takao Kawabe, Masao Omata
Pages: 1279-1287
Published online on: 01 November 2004

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Article

Inhibition of human hepatocellular carcinoma by L-proline-m-bis (2-chloroethyl) amino-L-phenylalanyl-L-norvaline ethyl ester hydrochloride (MF13) in vitro and in vivo

Qiong-Ying Hu, Jian-Nong Li, Dan-Qing Song, Yan-Ling Wang, George Bekesi, Imre Weisz, Jian-Dong Jiang
Pages: 1289-1296
Published online on: 01 November 2004

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Article

Mutations in the N-terminal domain of DFF45 in a primary germ cell tumor and in neuroblastoma tumors

Frida Abel, Rose-Marie Sjöberg, Cecilia Krona, Staffan Nilsson, Tommy Martinsson
Pages: 1297-1302
Published online on: 01 November 2004

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Article

Relationship between activation of epidermal growth factor receptor and cell dissociation in pancreatic cancer

Xiaodong Tan, Hiroshi Egami, Shinji Ishikawa, Masahide Nakagawa, Takatoshi Ishiko, Hidenobu Kamohara, Masahiko Hirota, Michio Ogawa
Pages: 1303-1309
Published online on: 01 November 2004

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Article

Schedule-dependent synergism of vinorelbine and 5-fluorouracil/UFT against non-small cell lung cancer

Shingo Matsumoto, Tadashi Igishi, Kiyoshi Hashimoto, Masahro Kodani, Yasushi Shigeoka, Hirofumi Nakanishi, Hirokazu Touge, Jun Kurai, Haruhiko Makino, Kenichi Takeda, Kazuhito Yasuda, Yutaka Hitsuda, Eiji Shimizu
Pages: 1311-1318
Published online on: 01 November 2004

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Article

CD80 gene therapy for lymph node involvement by gastric carcinoma

Kinshi Kosaka, Masakazu Yashiro, Yoji Sakate, Hiroaki Tanaka, Takeshi Sunami, Masaichi Ohira, Kosei Hirakawa
Pages: 1319-1325
Published online on: 01 November 2004

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Article

Influence of IGF-IR stimulation or blockade on proliferation of human renal cell carcinoma cell lines

Ann Rosendahl, Göran Forsberg
Pages: 1327-1336
Published online on: 01 November 2004

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Article

Expression of Wnt genes and frizzled 1 and 2 receptors in normal breast epithelium and infiltrating breast carcinoma

Tatjana Milovanovic, Kestutis Planutis, Anthony Nguyen, J. Lawrence Marsh, Fritz Lin, Christopher Hope, Randall F. Holcombe
Pages: 1337-1342
Published online on: 01 November 2004

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Article

A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer

Ryuichiro Yagyu, Yoichi Furukawa, Yu-Min Lin, Takashi Shimokawa, Takehira Yamamura, Yusuke Nakamura
Pages: 1343-1348
Published online on: 01 November 2004

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Article

Abnormal expression of cell cycle regulators in FUS-CHOP carrying liposarcomas

Anita Olofsson, Helena Willén, Melker Göransson, Katarina Engström, Jeanne M. Meis-Kindblom, Göran Stenman, Lars-Gunnar Kindblom, Pierre Åman
Pages: 1349-1355
Published online on: 01 November 2004

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Article

Genetic alterations in doxorubicin-resistant hepatocellular carcinoma cells: A combined study of spectral karyotyping, positional expression profiling and candidate genes

Ying Hu, Elizabeth Pang, Paul B.-S. Lai, Jeremy A. Squire, Pascale F. MacGregor, Ben Beheshti, Monique Albert, Thomas W.-T. Leung, Nathalie Wong
Pages: 1357-1364
Published online on: 01 November 2004

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Article

Model building and quantitative analysis of a tandem immuno-capturing assay as a screening tool for breast cancer

G. Pulido-Cejudo, K. El Abdaimi, C. Wang, B. Kar, J. Medina-Acevedo, J. M. Cardenas, E. J. Sarti-Gutierrez, M. Martinez-Dominguez
Pages: 1365-1374
Published online on: 01 November 2004

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Article

TGF-β-induced upregulation of MMP-2 and MMP-9 depends on p38 MAPK, but not ERK signaling in MCF10A human breast epithelial cells

Eun-Sook Kim, Mi-Sung Kim, Aree Moon
Pages: 1375-1382
Published online on: 01 November 2004

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Article

Analysis of isoform specific function of PP1 catalytic subunits in mammalian cells using siRNA

Tadashi Okada, Tsubasa Fujii, Nobuhiro Tanuma, Shinya Mitsuhashi, Takeshi Urano, Yoshio Araki, Hiroshi Shima, Kunimi Kikuchi
Pages: 1383-1388
Published online on: 01 November 2004

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Article

Soy isoflavones suppress invasiveness of breast cancer cells by the inhibition of NF-κB/AP-1-dependent and -independent pathways

Tatiana Valachovicova, Veronika Slivova, Heidi Bergman, Jennifer Shuherk, Daniel Sliva
Pages: 1389-1395
Published online on: 01 November 2004

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Article

Identification, validation, and clinical implementation of tumor-associated biomarkers to improve therapy concepts, survival, and quality of life of cancer patients: Tasks of the Receptor and Biomarker Group of the European Organization for Research and Treatment of Cancer

Manfred Schmitt, Nadia Harbeck, Maria Grazia Daidone, Nils BrYnner, M. Joe Duffy, John A. Foekens, Fred C.G.J. Sweep
Pages: 1397-1406
Published online on: 01 November 2004

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Article

Inhibition of matrix metalloproteinase-9 reduces in vitro invasion and angiogenesis in human microvascular endothelial cells

Unmesh Jadhav, Srinivasulu Chigurupati, Sajani S. Lakka, Sanjeeva Mohanam
Pages: 1407-1414
Published online on: 01 November 2004

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Article

Epigenetic silencing of E- and P-cadherin gene expression in human melanoma cell lines

Arata Tsutsumida, Jun-ichi Hamada, Mitsuhiro Tada, Tetsuya Aoyama, Keiji Furuuchi, Yoshiko Kawai, Yuhei Yamamoto, Tsuneki Sugihara, Tetsuya Moriuchi
Pages: 1415-1421
Published online on: 01 November 2004

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Article

Differentially expressed protein markers in human submandibular and sublingual secretions

Shen Hu, Patricia Denny, Paul Denny, Yongming Xie, Joseph A. Loo, Lawrence E. Wolinsky, Yang Li, Jim McBride, Rachel R. Ogorzalek Loo, Mavash Navazesh, David T. Wong
Pages: 1423-1430
Published online on: 01 November 2004

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Article

Trichostatin A induces apoptosis of p815 mastocytoma cells in histone acetylation- and mitochondria-dependent fashion

Su-Bog Yee, Myung Soo Kim, Soo Jin Baek, Gyoo Cheon Kim, Ki Soo Yoo, Young Hyun Yoo, Bong Soo Park
Pages: 1431-1436
Published online on: 01 November 2004

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Article

Proteasomes act in the pre-mitochondrial signal transduction route towards roscovitine-induced apoptosis

M. E.R. Henfling, F. C.S. Ramaekers, B. Schutte
Pages: 1437-1446
Published online on: 01 November 2004

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Article

p16INK4a polymorphism: associations with tumour progression in patients with sporadic colorectal cancer

Jonathan M. McCloud, Rangasamy Sivakumar, Alex Greenhough, Jackie Elder, Peter W. Jones, Mark Deakin, James B. Elder, Anthony A. Fryer, Paul R. Hoban
Pages: 1447-1452
Published online on: 01 November 2004

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Article

Primary B-cell lymphoma of the skin: The Sheffield Lymphoma Group Experience (1984-2003)

L. El-Helw, S. Goodwin, D. Slater, B. W. Hancock
Pages: 1453-1458
Published online on: 01 November 2004

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Article

Transactivation of E-cadherin is not involved in the activity of EGF receptor in colorectal carcinoma cells

Vlasta Sovová, Dana Kucerová, Martina Vojtechová, Eva Sloncová, Zdena Tuhácková
Pages: 1459-1464
Published online on: 01 November 2004

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Article

Polymorphisms in the methylenetetrahydrofolate reductase gene and prostate cancer risk

Rakesh Singal, Larry Ferdinand, Partha M. Das, Isildinha M. Reis, James J. Schlesselman
Pages: 1465-1471
Published online on: 01 November 2004

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Article

Correlation between topoisomerase-IIα gene amplification and protein expression in HER-2 amplified breast cancer

V. Durbecq, C. Desmed, M. Paesmans, F. Cardoso, A. Di Leo, M. Mano, G. Rouas, J.-Y. Leroy, C. Sotiriou, M. Piccart, D. Larsimont
Pages: 1473-1479
Published online on: 01 November 2004

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Article

Candidate genes upregulated in density dependent growth inhibition of lung cancer cells

Hartmut Kuhn, Jens Bräunlich, Stefan Hammerschmidt, Hubert Wirtz
Pages: 1481-1487
Published online on: 01 November 2004

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Article

Molecular analysis of the erbB gene family calmodulin-binding and calmodulin-like domains in astrocytic gliomas

Dolores Arjona, M. Josefa Bello, M. Eva Alonso, Pilar Gonzalez-Gomez, Jesus Lomas, Cinthia Aminoso, Isabel Lopez-Marin, Alberto Isla, Jose M. De Campos, Jesus Vaquero, Manuel Gutierrez, Antonio Villalobo, Juan A. Rey
Pages: 1489-1494
Published online on: 01 November 2004

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Review

Human FOX gene family (Review)

Masuko Katoh, Masaru Katoh
Pages: 1495-1500
Published online on: 01 November 2004

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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