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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2005 Volume 26 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Heterogeneous expression of the aquaporin 1 (AQP1) water channel in tumors of the prostate, breast, ovary, colon and lung: A study using high density multiple human tumor tissue microarrays

Ali Mobasheri, Rachel Airley, Stephen M. Hewitt, David Marples
Pages: 1149-1158
Published online on: 01 May 2005

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Article

Tumor and metastasis suppression by the human RNASET2 gene

Francesco Acquati, Laura Possati, Luigi Ferrante, Paola Campomenosi, Simona Talevi, Silvana Bardelli, Chiara Margiotta, Antonella Russo, Elisabetta Bortoletto, Romina Rocchetti, Roberta Calza, Raffaella Cinquetti, Laura Monti, Silvia Salis, Giuseppe Barbanti-Brodano, Roberto Taramelli
Pages: 1159-1168
Published online on: 01 May 2005

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Article

Augmentation of Fas ligand-induced apoptosis by MUC1 mucin

Rupesh Chaturvedi, Rakesh K. Srivastava, Akinori Hisatsune, Sharmila Shankar, Erik P. Lillehoj, K. Chul Kim
Pages: 1169-1176
Published online on: 01 May 2005

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Article

Expression of EGFR, HER2, HER3, and HER4 in metastatic squamous cell carcinomas of the oral cavity and base of tongue

T. Ekberg, M. Nestor, M. Engström, H. Nordgren, K. Wester, J. Carlsson, M. Anniko
Pages: 1177-1185
Published online on: 01 May 2005

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Article

DNA topoisomerase IIα and Her-2/neu gene dosages in pediatric malignant gliomas

Claudia Bredel, Silke Lassmann, Ian F. Pollack, Rolf Knoth, Ronald L. Hamilton, Benedikt Volk, Martin Werner, Markus Bredel
Pages: 1187-1192
Published online on: 01 May 2005

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Article

Differential expression and cytoplasm/membrane distribution of endoglin (CD105) in human tumour cell lines: Implications in the modulation of cell proliferation

L. Postiglione, G. Di Domenico, M. Caraglia, M. Marra, G. Giuberti, L. Del Vecchio, S. Montagnani, M. Macri, E. M. Bruno, A. Abbruzzese, G. Rossi
Pages: 1193-1201
Published online on: 01 May 2005

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Article

Enhanced expression and activation of major matrix metalloproteinases in distinct topographic areas of invasive breast carcinomas

Beatrice E. Bachmeier, Helmut Rohrbach, Johann De Waal, Marianne Jochum, Andreas G. Nerlich
Pages: 1203-1207
Published online on: 01 May 2005

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Article

FGF7-like gene is associated with pericentric inversion of chromosome 9, and FGF7 is involved in the development of ovarian cancer

Takaomi Yasuhara, Aikou Okamoto, Takanori Kitagawa, Takashi Nikaido, Tomoaki Yoshimura, Nozomu Yanaihara, Satoshi Takakura, Tadao Tanaka, Kazunori Ochiai, Yasuyuki Ohtake
Pages: 1209-1216
Published online on: 01 May 2005

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Article

Methylation and expression of p16INK4 tumor suppressor gene in primary colorectal cancer tissues

Byung No Kim, Hirofumi Yamamoto, Kimimasa Ikeda, Bazarragchaa Damdinsuren, Yurika Sugita, Chew Yee Ngan, Yujiro Fujie, Minoru Ogawa, Taishi Hata, Masataka Ikeda, Masayuki Ohue, Mitsugu Sekimoto, Takushi Monden, Nariaki Matsuura, Morito Monden
Pages: 1217-1226
Published online on: 01 May 2005

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Article

The level of telomere dysfunction determines the efficacy of telomerase-based therapeutics in a lung cancer cell line

Milena Pantic, Stefan Zimmermann, Cornelius F. Waller, Uwe M. Martens
Pages: 1227-1232
Published online on: 01 May 2005

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Article

Genetically engineered mouse melanoma and mouse Lewis lung carcinoma models

Zoya Galcheva-Gargova, Yi Wei Qi, Sarah Geisler, Natalia Zhidkova, Matthew A. Nugent, Ganesh Venkataraman
Pages: 1233-1239
Published online on: 01 May 2005

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Review

Involvement of the ras genes in female genital tract cancer (Review)

Ioannis N. Mammas, Alexandros Zafiropoulos, Demetrios A. Spandidos
Pages: 1241-1255
Published online on: 01 May 2005

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Article

Differential sensitivity of BRCA1-mutated HCC1937 human breast cancer cells to microtubule-interfering agents

Pierfrancesco Tassone, Simona Blotta, Camillo Palmieri, Serena Masciari, Barbara Quaresima, Marco Montagna, Emma D'Andrea, Orietta P. Eramo, Leonardo Migale, Francesco Costanzo, Pierosandro Tagliaferri, Salvatore Venuta
Pages: 1257-1263
Published online on: 01 May 2005

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Article

Loss of caspase-1 gene expression in human gastric carcinomas and cell lines

Chang Do Jee, Hye Seung Lee, Soo In Bae, Han Kwang Yang, You Mie Lee, Min Suk Rho, Woo Ho Kim
Pages: 1265-1271
Published online on: 01 May 2005

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Article

Expression of TNF-related apoptosis-inducing ligand in human hepatocellular carcinoma

Katsuya Shiraki, Takenari Yamanaka, Hidekazu Inoue, Tomoyuki Kawakita, Naoyuki Enokimura, Hiroshi Okano, Kazushi Sugimoto, Kazumoto Murata, Takeshi Nakano
Pages: 1273-1281
Published online on: 01 May 2005

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Article

Involvement of matrix metalloproteinase-7 in invasion-metastasis through induction of cell dissociation in pancreatic cancer

Xiaodong Tan, Hiroshi Egami, Shinji Ishikawa, Hideki Sugita, Hidenobu Kamohara, Masahide Nakagawa, Fumiaki Nozawa, Michio Abe, Michio Ogawa
Pages: 1283-1289
Published online on: 01 May 2005

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Article

Hydrogen peroxide overload increases adriamycin-induced apoptosis of SaOS2FM, a manganese superoxide dismutase-overexpressing human osteosarcoma cell line

Yadi Wang, Masahiro Kuroda, Xian-Shu Gao, Jun-Ichi Asaumi, Kohichi Shibuya, Shoji Kawasaki, Shiro Akaki, Daret St. Clair, Yoshio Hiraki, Susumu Kanazawa
Pages: 1291-1300
Published online on: 01 May 2005

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Article

Blocking of PI3K/Akt pathway enhances apoptosis induced by SN-38, an active form of CPT-11, in human hepatoma cells

Naoki Koizumi, Etsuro Hatano, Takashi Nitta, Masaharu Tada, Nobuko Harada, Kojiro Taura, Iwao Ikai, Yasuyuki Shimahara
Pages: 1301-1306
Published online on: 01 May 2005

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Article

Clinical significance of categorisation of mammographic density for breast cancer prognosis

Mariko Morishita, Akira Ohtsuru, Tomayoshi Hayashi, Ichiro Isomoto, Noriaki Itoyanagi, Shigeto Maeda, Sumihisa Honda, Hiroshi Yano, Tatsuya Uga, Takeshi Nagayasu, Takashi Kanematsu, Shunichi Yamashita
Pages: 1307-1312
Published online on: 01 May 2005

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Article

Vaccination with dendritic cells pulsed with apoptotic cells elicits effective antitumor immunity in murine hepatoma models

Toshinobu Hayashi, Kazuhiko Nakao, Yuji Nagayama, Ohki Saitoh, Tatsuki Ichikawa, Hiroki Ishikawa, Keisuke Hamasaki, Katsumi Eguchi, Nobuko Ishii
Pages: 1313-1319
Published online on: 01 May 2005

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Article

Overexpression of the N-terminal end of the p55γ regulatory subunit of phosphatidylinositol 3-kinase blocks cell cycle progression in gastric carcinoma cells

Junbo Hu, Shuangyou Liu, Jing Wang, Xuelai Luo, Xia Gao, Xianmin Xia, Yongdong Feng, Deding Tao, Gangduo Wang, Xiping Li, Jinshun Zhao, Hong Ding, Eddie Reed, Qingdi Q. Li, Jianping Gong
Pages: 1321-1327
Published online on: 01 May 2005

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Article

Clonality analysis of childhood neuroblastoma by polymerase chain reaction for the human androgen receptor gene

Lisong Shen, Zhenghong Wu, Tatsuo Kuroda, Toshiro Honna, Yukichi Tanaka, Jun Miyauchi
Pages: 1329-1335
Published online on: 01 May 2005

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Article

in vitro and in vivo antitumor effects of vitamin K5 on hepatocellular carcinoma

Misuzu Hitomi, Takako Nonomura, Fumi Yokoyama, Hitoshi Yoshiji, Mutsumi Ogawa, Seiji Nakai, Akihiro Deguchi, Tsutomu Masaki, Hideyuki Inoue, Yasuhiko Kimura, Kazutaka Kurokohchi, Naohito Uchida, Shigeki Kuriyama
Pages: 1337-1344
Published online on: 01 May 2005

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Article

Histone deacetylase inhibitors, N-butyric acid and trichostatin A, induce caspase-8- but not caspase-9-dependent apoptosis in human malignant glioma cells

T. Komata, T. Kanzawa, T. Nashimoto, H. Aoki, S. Endo, T. Kon, H. Takahashi, S. Kondo, R. Tanaka
Pages: 1345-1352
Published online on: 01 May 2005

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Article

Epithelial and prostatic marker expression in short-term primary cultures of human prostate tissue samples

Claudio Festuccia, Adriano Angelucci, Giovanni Luca Gravina, Paola Muzi, Roberto Miano, Carlo Vicentini, Mauro Bologna
Pages: 1353-1362
Published online on: 01 May 2005

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Article

Matrix metalloproteinase-2 and matrix metalloproteinase-9 type IV collagenases in serum of patients with pleural effusions

Angelina Di Carlo, Daniela Terracciano, Angela Mariano, Vincenzo Macchia
Pages: 1363-1368
Published online on: 01 May 2005

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Article

Mxi1 isoforms are expressed in hematological cell lines and normal bone marrow

Norihiko Kawamata, Kei-Ji Sugimoto, Sakura Sakajiri, Kazuo Oshimi, H. Phillip Koeffler
Pages: 1369-1375
Published online on: 01 May 2005

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Article

Glucose metabolism in brain tumours can be estimated using [18F]2-fluorodeoxyglucose positron emission tomography and a population-derived input function scaled using a single arterialised venous blood sample

C. S. Brock, H. Young, S. Osman, S. K. Luthra, T. Jones, P. M. Price
Pages: 1377-1383
Published online on: 01 May 2005

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Article

Deletions and altered expression of the RIZ1 tumour suppressor gene in 1p36 in pheochromocytomas and abdominal paragangliomas

Janos Geli, Brita Nord, Tony Frisk, Elisabeth Edström Elder, Tomas J. Ekström, Tobias Carling, Martin Bäckdahl, Catharina Larsson
Pages: 1385-1391
Published online on: 01 May 2005

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Article

COX-2 overexpression increases motility and invasion of breast cancer cells

Balraj Singh, Jacob A. Berry, Angela Shoher, Vijay Ramakrishnan, Anthony Lucci
Pages: 1393-1399
Published online on: 01 May 2005

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Article

Radiation-induced autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells

Hideaki Ito, Shigeru Daido, Takao Kanzawa, Seiji Kondo, Yasuko Kondo
Pages: 1401-1410
Published online on: 01 May 2005

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Article

Characterization of Sno expression in malignant melanoma

Ina Poser, Tanja Rothhammer, Steven Dooley, Ralf Weiskirchen, Anja-Katrin Bosserhoff
Pages: 1411-1417
Published online on: 01 May 2005

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Article

Expression of cyclooxygenase-2 in uterine endometrial cancer and anti-tumor effects of a selective COX-2 inhibitor

Kiyoshi Hasegawa, Yoshimasa Ohashi, Kunimi Ishikawa, Akira Yasue, Rina Kato, Yumiko Achiwa, Eiji Nishio, Yasuhiro Udagawa
Pages: 1419-1428
Published online on: 01 May 2005

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Article

Genetic manipulation of stromal cell-derived factor-1 attests the pivotal role of the autocrine SDF-1-CXCR4 pathway in the aggressiveness of breast cancer cells

Hua Kang, Robert E. Mansel, Wen G. Jiang
Pages: 1429-1434
Published online on: 01 May 2005

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Article

Comparative genomics on Vangl1 and Vangl2 genes

Yuriko Katoh, Masaru Katoh
Pages: 1435-1440
Published online on: 01 May 2005

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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