Journal Articles

Angiogenesis: An update and potential drug approaches (Review)

Maen Abdelrahim, Santhi Konduri, Md. Riyaz Basha, Philip A. Philip, Cheryl H. Baker

Pages: 5-18 Published online on: 01 January 2010

A novel pharmacodynamic approach to assess and predict tumor response to the epidermal growth factor receptor inhibitor gefitinib in patients with esophageal cancer

Soner Altiok, Heather Mezzadra, Sanjay Jagannath, Nancy Tsottles, Michelle A. Rudek, Nadia Abdallah, David Berman, Arlene Forastiere, Michael K. Gibson

Pages: 19-27 Published online on: 01 January 2010
Open Access

PNA-mediated modulation and redirection of Her-2 pre-mRNA splicing: Specific skipping of erbB-2 exon 19 coding for the ATP catalytic domain

Stanislava Pankratova, Birgit N. Nielsen, Takehiko Shiraishi, Peter E. Nielsen

Pages: 29-38 Published online on: 01 January 2010
Open Access

Cyclin D1b represses breast cancer cell growth by antagonizing the action of cyclin D1a on estrogen receptor α-mediated transcription

Jing Zhu, Subrata Sen, Chongjuan Wei, Marsha L. Frazier

Pages: 39-48 Published online on: 01 January 2010

Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition

Tobias Kiesslich, Beate Alinger, Gernot W. Wolkersdörfer, Matthias Ocker, Daniel Neureiter, Frieder Berr

Pages: 49-58 Published online on: 01 January 2010

Inhibition of AP-1 and MAPK signaling and activation of Nrf2/ARE pathway by quercitrin

Min Ding, Jinshun Zhao, Linda Bowman, Yongju Lu, Xianglin Shi

Pages: 59-67 Published online on: 01 January 2010

Atelocollagen-delivered siRNA targeting the FABP5 gene as an experimental therapy for prostate cancer in mouse xenografts

Shiva S. Forootan, Zheng Z. Bao, Farzad S. Forootan, Laleh Kamalian, Yu Zhang, Alix Bee, Christopher S. Foster, Youqiang Ke

Pages: 69-76 Published online on: 01 January 2010

Target chemotherapy of anti-CD147 antibody-labeled liposome encapsulated GSH-DXR conjugate on CD147 highly expressed carcinoma cells

Hiroshi Matsudaira, Tadashi Asakura, Katsuhiko Aoki, Yasuyuki Searashi, Tomokazu Matsuura, Hisato Nakajima, Hisao Tajiri, Kiyoshi Ohkawa

Pages: 77-83 Published online on: 01 January 2010
Open Access

Epigenetic silencing of RELN in gastric cancer

Osamu Dohi, Hisashi Takada, Naoki Wakabayashi, Kohichiroh Yasui, Chouhei Sakakura, Shoji Mitsufuji, Yuji Naito, Masafumi Taniwaki, Toshikazu Yoshikawa

Pages: 85-92 Published online on: 01 January 2010

Differential proteomic analysis of hepatocellular carcinoma

Giuseppe Corona, Elisa De Lorenzo, Caterina Elia, Maria Paola Simula, Claudio Avellini, Umberto Baccarani, Francesco Lupo, Claudio Tiribelli, Alfonso Colombatti, Giuseppe Toffoli

Pages: 93-99 Published online on: 01 January 2010

Use of protein array to investigate receptor tyrosine kinases activated in gastric cancer

Jian Gong, Asahiro Morishita, Kazutaka Kurokohchi, Joji Tani, Kiyohito Kato, Hisaaki Miyoshi, Hideyuki Inoue, Mitsuyoshi Kobayashi, Shi Liu, Masayuki Murota, Akemi Muramatsu, Kunihiko Izuishi, Yasuyuki Suzuki, Hirohito Yoshida, Naohito Uchida, Kazushi Deguchi, Hisakazu Iwama, Ichiro Ishimaru, Tsutomu Masaki

Pages: 101-106 Published online on: 01 January 2010
Open Access

Serine 2481-autophosphorylation of mammalian target of rapamycin (mTOR) couples with chromosome condensation and segregation during mitosis: Confocal microscopy characterization and immunohistochemical validation of PP-mTORSer2481 as a novel high-contrast mitosis marker in breast cancer core biopsies

Eugeni Lopez-Bonet, Alejandro Vazquez-Martin, Maria Carmen Pérez-Martínez, Cristina Oliveras-Ferraros, Ferran Pérez-Bueno, Luis Bernadó, Javier A. Menendez

Pages: 107-115 Published online on: 01 January 2010

Hypoxia switches glucose depletion-induced necrosis to phosphoinositide 3-kinase/Akt-dependent apoptosis in A549 lung adenocarcinoma cells

Cho Hee Kim, A. Ra Ko, Su Yeon Lee, Hyun Min Jeon, Sun Mi Kim, Hye Gyeong Park, Song Iy Han, Ho Sung Kang

Pages: 117-124 Published online on: 01 January 2010

Anti-tumor effect of apicidin on Ishikawa human endometrial cancer cells both in vitro and in vivo by blocking histone deacetylase 3 and 4

Mee Young Ahn, Hae Young Chung, Wahn Soo Choi, Byung Mu Lee, Sungpil Yoon, Hyung Sik Kim

Pages: 125-131 Published online on: 01 January 2010

Exosomes derived from IL-12-anchored renal cancer cells increase induction of specific antitumor response in vitro: A novel vaccine for renal cell carcinoma

Yao Zhang, Chun-Li Luo, Bai-Cheng He, Jia-Mo Zhang, Gang Cheng, Xiao-Hou Wu

Pages: 133-140 Published online on: 01 January 2010

Overexpression of HOXB7 homeobox gene in oral cancer induces cellular proliferation and is associated with poor prognosis

Maria Fernanda De Souza Setubal Destro, Carolina Cavalcanti Bitu, Karina G. Zecchin, Edgard Graner, Marcio A. Lopes, Luis Paulo Kowalski, Ricardo D. Coletta

Pages: 141-149 Published online on: 01 January 2010

Expression of Epstein-Barr nuclear antigen 1 in gastric carcinoma cells is associated with enhanced tumorigenicity and reduced cisplatin sensitivity

Tse-Chou Cheng, Shan-Shan Hsieh, Wen-Lin Hsu, Yu-Fang Chen, Hwei-Hon Ho, Lai-Fa Sheu

Pages: 151-160 Published online on: 01 January 2010

Hypoxia-induced des-γ-carboxy prothrombin production in hepatocellular carcinoma

Kazumoto Murata, Hideto Suzuki, Hiroshi Okano, Takashi Oyamada, Yoshikazu Yasuda, Atsushi Sakamoto

Pages: 161-170 Published online on: 01 January 2010

Frequent aberrant methylation of the imprinted IGF2/H19 locus and LINE1 hypomethylation in ovarian carcinoma

Reinhard H. Dammann, Sebastian Kirsch, Undraga Schagdarsurengin, Temuujin Dansranjavin, Elise Gradhand, Wolfgang D. Schmitt, Steffen Hauptmann

Pages: 171-179 Published online on: 01 January 2010

ICAM-3 enhances the migratory and invasive potential of human non-small cell lung cancer cells by inducing MMP-2 and MMP-9 via Akt and CREB

Jong Kuk Park, Seon Ho Park, Kwangsup So, In Hwa Bae, Young Do Yoo, Hong-Duck Um

Pages: 181-192 Published online on: 01 January 2010

N-glycosylation status of β-haptoglobin in sera of patients with prostate cancer vs. benign prostate diseases

Seon-Joo Yoon, Seung-Yeol Park, Poh-Choo Pang, Jenni Gallagher, James E. Gottesman, Anne Dell, Jung-Hoe Kim, Sen-Itiroh Hakomori

Pages: 193-203 Published online on: 01 January 2010

The assessment of methylated BASP1 and SRD5A2 levels in the detection of early hepatocellular carcinoma

Ryouichi Tsunedomi, Yasushi Ogawa, Norio Iizuka, Kazuhiko Sakamoto, Takao Tamesa, Toyoki Moribe, Masaaki Oka

Pages: 205-212 Published online on: 01 January 2010

Pharmacokinetics, biodistribution and metabolism of a novel selective androgen receptor modulator designed for prostate cancer imaging

Jun Yang, Zengru Wu, Di Wu, Michael V. Darby, Seoung Soo Hong, Duane D. Miller, James T. Dalton

Pages: 213-222 Published online on: 01 January 2010

The peroxisome proliferator-activated receptor γ ligands, pioglitazone and 15-deoxy-Δ12,14-prostaglandin J2, have antineoplastic effects against hepatitis B virus-associated hepatocellular carcinoma cells

Jaejun Shim, Byung-Ho Kim, Young Il Kim, Kyung Yup Kim, Young Hwangbo, Jae Young Jang, Seok Ho Dong, Hyo Jong Kim, Young Woon Chang, Rin Chang

Pages: 223-231 Published online on: 01 January 2010

A fiber modified adenovirus vector that targets to the EphrinA2 receptor reveals enhanced gene transfer to ex vivo pancreatic cancer

Michael A. Van Geer, Daniel Brevoord, Koert F.D. Kuhlmann, Conny T. Bakker, Hiroyuki Mizuguchi, John G. Wesseling, Fibo J. Ten Kate, Dirk J. Gouma, Ronald P.J. Oude Elferink, Piter J. Bosma

Pages: 233-244 Published online on: 01 January 2010

Loss of liver-intestine cadherin in human intrahepatic cholangiocarcinoma promotes angiogenesis by up-regulating metal-responsive transcription factor-1 and placental growth factor

Masaaki Takamura, Satoshi Yamagiwa, Toshifumi Wakai, Yasushi Tamura, Hiroteru Kamimura, Takashi Kato, Atsunori Tsuchiya, Yasunobu Matsuda, Yoshio Shirai, Takafumi Ichida, Yoichi Ajioka, Yutaka Aoyagi

Pages: 245-254 Published online on: 01 January 2010

Alterations in a defined extracellular region of the RON receptor tyrosine kinase promote RON-mediated motile and invasive phenotypes in epithelial cells

Kun Zhang, Yong-Qing Zhou, Hang-Ping Yao, Ming-Hai Wang

Pages: 255-264 Published online on: 01 January 2010

Comparative proteomic analysis of the esophageal squamous carcinoma cell line EC109 and its multi-drug resistant subline EC109/CDDP

Jing Wen, Bin Zheng, Yi Hu, Xu Zhang, Hong Yang, Yan Li, Chun-Yu Zhang, Kong-Jia Luo, Xing Zang, Yong-Feng Li, Xin-Yuan Guan, Jian-Hua Fu

Pages: 265-274 Published online on: 01 January 2010

Expression of proteinase inhibitor-9/serpinB9 in non-small cell lung carcinoma cells and tissues

Ilona Rousalova, Evzen Krepela, Jan Prochazka, Jan Cermak, Kamila Benkova

Pages: 275-283 Published online on: 01 January 2010
Open Access

Cell cycle effects of fatty acid derivatives of cytarabine, CP-4055, and of gemcitabine, CP-4126, as basis for the interaction with oxaliplatin and docetaxel

A. D. Adema, A. C. Laan, F. Myhren, I. Fichtner, H. M. Verheul, M. L. Sandvold, G. J. Peters

Pages: 285-294 Published online on: 01 January 2010
Journal Cover

Cover Legend PDF

January 2010
Volume 36 Issue 1

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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