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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2010 Volume 36 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Angiogenesis: An update and potential drug approaches (Review)

Maen Abdelrahim, Santhi Konduri, Md. Riyaz Basha, Philip A. Philip, Cheryl H. Baker
Pages: 5-18
Published online on: 01 January 2010

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Article

A novel pharmacodynamic approach to assess and predict tumor response to the epidermal growth factor receptor inhibitor gefitinib in patients with esophageal cancer

Soner Altiok, Heather Mezzadra, Sanjay Jagannath, Nancy Tsottles, Michelle A. Rudek, Nadia Abdallah, David Berman, Arlene Forastiere, Michael K. Gibson
Pages: 19-27
Published online on: 01 January 2010

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Article Open Access

PNA-mediated modulation and redirection of Her-2 pre-mRNA splicing: Specific skipping of erbB-2 exon 19 coding for the ATP catalytic domain

Stanislava Pankratova, Birgit N. Nielsen, Takehiko Shiraishi, Peter E. Nielsen
Pages: 29-38
Published online on: 01 January 2010

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Article Open Access

Cyclin D1b represses breast cancer cell growth by antagonizing the action of cyclin D1a on estrogen receptor α-mediated transcription

Jing Zhu, Subrata Sen, Chongjuan Wei, Marsha L. Frazier
Pages: 39-48
Published online on: 01 January 2010

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Article

Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition

Tobias Kiesslich, Beate Alinger, Gernot W. Wolkersdörfer, Matthias Ocker, Daniel Neureiter, Frieder Berr
Pages: 49-58
Published online on: 01 January 2010

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Article

Inhibition of AP-1 and MAPK signaling and activation of Nrf2/ARE pathway by quercitrin

Min Ding, Jinshun Zhao, Linda Bowman, Yongju Lu, Xianglin Shi
Pages: 59-67
Published online on: 01 January 2010

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Article

Atelocollagen-delivered siRNA targeting the FABP5 gene as an experimental therapy for prostate cancer in mouse xenografts

Shiva S. Forootan, Zheng Z. Bao, Farzad S. Forootan, Laleh Kamalian, Yu Zhang, Alix Bee, Christopher S. Foster, Youqiang Ke
Pages: 69-76
Published online on: 01 January 2010

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Article

Target chemotherapy of anti-CD147 antibody-labeled liposome encapsulated GSH-DXR conjugate on CD147 highly expressed carcinoma cells

Hiroshi Matsudaira, Tadashi Asakura, Katsuhiko Aoki, Yasuyuki Searashi, Tomokazu Matsuura, Hisato Nakajima, Hisao Tajiri, Kiyoshi Ohkawa
Pages: 77-83
Published online on: 01 January 2010

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Article Open Access

Epigenetic silencing of RELN in gastric cancer

Osamu Dohi, Hisashi Takada, Naoki Wakabayashi, Kohichiroh Yasui, Chouhei Sakakura, Shoji Mitsufuji, Yuji Naito, Masafumi Taniwaki, Toshikazu Yoshikawa
Pages: 85-92
Published online on: 01 January 2010

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Article

Differential proteomic analysis of hepatocellular carcinoma

Giuseppe Corona, Elisa De Lorenzo, Caterina Elia, Maria Paola Simula, Claudio Avellini, Umberto Baccarani, Francesco Lupo, Claudio Tiribelli, Alfonso Colombatti, Giuseppe Toffoli
Pages: 93-99
Published online on: 01 January 2010

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Article

Use of protein array to investigate receptor tyrosine kinases activated in gastric cancer

Jian Gong, Asahiro Morishita, Kazutaka Kurokohchi, Joji Tani, Kiyohito Kato, Hisaaki Miyoshi, Hideyuki Inoue, Mitsuyoshi Kobayashi, Shi Liu, Masayuki Murota, Akemi Muramatsu, Kunihiko Izuishi, Yasuyuki Suzuki, Hirohito Yoshida, Naohito Uchida, Kazushi Deguchi, Hisakazu Iwama, Ichiro Ishimaru, Tsutomu Masaki
Pages: 101-106
Published online on: 01 January 2010

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Article Open Access

Serine 2481-autophosphorylation of mammalian target of rapamycin (mTOR) couples with chromosome condensation and segregation during mitosis: Confocal microscopy characterization and immunohistochemical validation of PP-mTORSer2481 as a novel high-contrast mitosis marker in breast cancer core biopsies

Eugeni Lopez-Bonet, Alejandro Vazquez-Martin, Maria Carmen Pérez-Martínez, Cristina Oliveras-Ferraros, Ferran Pérez-Bueno, Luis Bernadó, Javier A. Menendez
Pages: 107-115
Published online on: 01 January 2010

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Article

Hypoxia switches glucose depletion-induced necrosis to phosphoinositide 3-kinase/Akt-dependent apoptosis in A549 lung adenocarcinoma cells

Cho Hee Kim, A. Ra Ko, Su Yeon Lee, Hyun Min Jeon, Sun Mi Kim, Hye Gyeong Park, Song Iy Han, Ho Sung Kang
Pages: 117-124
Published online on: 01 January 2010

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Article

Anti-tumor effect of apicidin on Ishikawa human endometrial cancer cells both in vitro and in vivo by blocking histone deacetylase 3 and 4

Mee Young Ahn, Hae Young Chung, Wahn Soo Choi, Byung Mu Lee, Sungpil Yoon, Hyung Sik Kim
Pages: 125-131
Published online on: 01 January 2010

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Article

Exosomes derived from IL-12-anchored renal cancer cells increase induction of specific antitumor response in vitro: A novel vaccine for renal cell carcinoma

Yao Zhang, Chun-Li Luo, Bai-Cheng He, Jia-Mo Zhang, Gang Cheng, Xiao-Hou Wu
Pages: 133-140
Published online on: 01 January 2010

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Article

Overexpression of HOXB7 homeobox gene in oral cancer induces cellular proliferation and is associated with poor prognosis

Maria Fernanda De Souza Setubal Destro, Carolina Cavalcanti Bitu, Karina G. Zecchin, Edgard Graner, Marcio A. Lopes, Luis Paulo Kowalski, Ricardo D. Coletta
Pages: 141-149
Published online on: 01 January 2010

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Article

Expression of Epstein-Barr nuclear antigen 1 in gastric carcinoma cells is associated with enhanced tumorigenicity and reduced cisplatin sensitivity

Tse-Chou Cheng, Shan-Shan Hsieh, Wen-Lin Hsu, Yu-Fang Chen, Hwei-Hon Ho, Lai-Fa Sheu
Pages: 151-160
Published online on: 01 January 2010

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Article

Hypoxia-induced des-γ-carboxy prothrombin production in hepatocellular carcinoma

Kazumoto Murata, Hideto Suzuki, Hiroshi Okano, Takashi Oyamada, Yoshikazu Yasuda, Atsushi Sakamoto
Pages: 161-170
Published online on: 01 January 2010

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Article

Frequent aberrant methylation of the imprinted IGF2/H19 locus and LINE1 hypomethylation in ovarian carcinoma

Reinhard H. Dammann, Sebastian Kirsch, Undraga Schagdarsurengin, Temuujin Dansranjavin, Elise Gradhand, Wolfgang D. Schmitt, Steffen Hauptmann
Pages: 171-179
Published online on: 01 January 2010

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Article

ICAM-3 enhances the migratory and invasive potential of human non-small cell lung cancer cells by inducing MMP-2 and MMP-9 via Akt and CREB

Jong Kuk Park, Seon Ho Park, Kwangsup So, In Hwa Bae, Young Do Yoo, Hong-Duck Um
Pages: 181-192
Published online on: 01 January 2010

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Article

N-glycosylation status of β-haptoglobin in sera of patients with prostate cancer vs. benign prostate diseases

Seon-Joo Yoon, Seung-Yeol Park, Poh-Choo Pang, Jenni Gallagher, James E. Gottesman, Anne Dell, Jung-Hoe Kim, Sen-Itiroh Hakomori
Pages: 193-203
Published online on: 01 January 2010

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Article

The assessment of methylated BASP1 and SRD5A2 levels in the detection of early hepatocellular carcinoma

Ryouichi Tsunedomi, Yasushi Ogawa, Norio Iizuka, Kazuhiko Sakamoto, Takao Tamesa, Toyoki Moribe, Masaaki Oka
Pages: 205-212
Published online on: 01 January 2010

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Article

Pharmacokinetics, biodistribution and metabolism of a novel selective androgen receptor modulator designed for prostate cancer imaging

Jun Yang, Zengru Wu, Di Wu, Michael V. Darby, Seoung Soo Hong, Duane D. Miller, James T. Dalton
Pages: 213-222
Published online on: 01 January 2010

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Article

The peroxisome proliferator-activated receptor γ ligands, pioglitazone and 15-deoxy-Δ12,14-prostaglandin J2, have antineoplastic effects against hepatitis B virus-associated hepatocellular carcinoma cells

Jaejun Shim, Byung-Ho Kim, Young Il Kim, Kyung Yup Kim, Young Hwangbo, Jae Young Jang, Seok Ho Dong, Hyo Jong Kim, Young Woon Chang, Rin Chang
Pages: 223-231
Published online on: 01 January 2010

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Article

A fiber modified adenovirus vector that targets to the EphrinA2 receptor reveals enhanced gene transfer to ex vivo pancreatic cancer

Michael A. Van Geer, Daniel Brevoord, Koert F.D. Kuhlmann, Conny T. Bakker, Hiroyuki Mizuguchi, John G. Wesseling, Fibo J. Ten Kate, Dirk J. Gouma, Ronald P.J. Oude Elferink, Piter J. Bosma
Pages: 233-244
Published online on: 01 January 2010

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Article

Loss of liver-intestine cadherin in human intrahepatic cholangiocarcinoma promotes angiogenesis by up-regulating metal-responsive transcription factor-1 and placental growth factor

Masaaki Takamura, Satoshi Yamagiwa, Toshifumi Wakai, Yasushi Tamura, Hiroteru Kamimura, Takashi Kato, Atsunori Tsuchiya, Yasunobu Matsuda, Yoshio Shirai, Takafumi Ichida, Yoichi Ajioka, Yutaka Aoyagi
Pages: 245-254
Published online on: 01 January 2010

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Article

Alterations in a defined extracellular region of the RON receptor tyrosine kinase promote RON-mediated motile and invasive phenotypes in epithelial cells

Kun Zhang, Yong-Qing Zhou, Hang-Ping Yao, Ming-Hai Wang
Pages: 255-264
Published online on: 01 January 2010

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Article

Comparative proteomic analysis of the esophageal squamous carcinoma cell line EC109 and its multi-drug resistant subline EC109/CDDP

Jing Wen, Bin Zheng, Yi Hu, Xu Zhang, Hong Yang, Yan Li, Chun-Yu Zhang, Kong-Jia Luo, Xing Zang, Yong-Feng Li, Xin-Yuan Guan, Jian-Hua Fu
Pages: 265-274
Published online on: 01 January 2010

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Article

Expression of proteinase inhibitor-9/serpinB9 in non-small cell lung carcinoma cells and tissues

Ilona Rousalova, Evzen Krepela, Jan Prochazka, Jan Cermak, Kamila Benkova
Pages: 275-283
Published online on: 01 January 2010

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Article Open Access

Cell cycle effects of fatty acid derivatives of cytarabine, CP-4055, and of gemcitabine, CP-4126, as basis for the interaction with oxaliplatin and docetaxel

A. D. Adema, A. C. Laan, F. Myhren, I. Fichtner, H. M. Verheul, M. L. Sandvold, G. J. Peters
Pages: 285-294
Published online on: 01 January 2010

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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