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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2011 Volume 38 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Role of endogenous cholecystokinin on growth of human pancreatic cancer

Gail L. Matters, Christopher McGovern, John F. Harms, Kevin Markovic, Krystal Anson, Calpurnia Jayakumar, Melissa Martenis, Christina Awad, Jill P. Smith
Pages: 593-601
Published online on: 24 December 2010

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Anti-proliferative potential of curcumin in androgen-dependent prostate cancer cells occurs through modulation of the Wingless signaling pathway

Marie-Hélène Teiten, François Gaascht, Marcus Cronauer, Estelle Henry, Mario Dicato, Marc Diederich
Pages: 603-611
Published online on: 14 January 2011

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Article Open Access

Flexible hysteroscopy with narrow band imaging (NBI) for endoscopic diagnosis of malignant endometrial lesions

Iori Kisu, Kouji Banno, Yusuke Kobayashi, Asuka Ono, Kenta Masuda, Arisa Ueki, Hiroyuki Nomura, Akira Hirasawa, Takayuki Abe, Keisuke Kouyama, Nobuyuki Susumu, Daisuke Aoki
Pages: 613-618
Published online on: 14 January 2011

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Article

Tumor-associated MUC5AC stimulates in vivo tumorigenicity of human pancreatic cancer

Hirotaka Hoshi, Tetsuji Sawada, Motoyuki Uchida, Hikaru Saito, Hiroko Iijima, Mikako Toda-Agetsuma, Tsutomu Wada, Sadaaki Yamazoe, Hiroaki Tanaka, Kenjiro Kimura, Anna Kakehashi, Min Wei, Kosei Hirakawa, Hideki Wanibuchi
Pages: 619-627
Published online on: 18 January 2011

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Article

High EGFR mRNA expression is a prognostic factor for reduced survival in pancreatic cancer after gemcitabine-based adjuvant chemotherapy

Hayato Fujita, Kenoki Ohuchida, Kazuhiro Mizumoto, Soichi Itaba, Tetsuhide Ito, Kohei Nakata, Jun Yu, Tadashi Kayashima, Akifumi Hayashi, Ryota Souzaki, Tatsuro Tajiri, Manabu Onimaru, Tatsuya Manabe, Takao Ohtsuka, Masao Tanaka
Pages: 629-641
Published online on: 17 January 2011

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Combined treatment with bortezomib plus bafilomycin A1 enhances the cytocidal effect and induces endoplasmic reticulum stress in U266 myeloma cells: Crosstalk among proteasome, autophagy-lysosome and ER stress

Tomohiro Kawaguchi, Keisuke Miyazawa, Shota Moriya, Tadashi Ohtomo, Xiao-Fang Che, Munekazu Naito, Masahiro Itoh, Akio Tomoda
Pages: 643-654
Published online on: 21 December 2010

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Cancer-associated fibroblasts correlate with poor prognosis in rectal cancer after chemoradiotherapy

Susumu Saigusa, Yuji Toiyama, Koji Tanaka, Takeshi Yokoe, Yoshinaga Okugawa, Hiroyuki Fujikawa, Kohei Matsusita, Mikio Kawamura, Yasuhiro Inoue, Chikao Miki, Masato Kusunoki
Pages: 655-663
Published online on: 14 January 2011

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Hydroxyflutamide enhances cellular sensitivity to 5-fluorouracil by suppressing thymidylate synthase expression in bicalutamide-resistant human prostate cancer cells

Rumi Kawabata, Shinji Oie, Toshinori Oka, Masayuki Takahashi, Hiroomi Kanayama, Kohji Itoh
Pages: 665-676
Published online on: 17 January 2011

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Increase in clusterin forms part of the stress response in Hodgkin's lymphoma

Raffaele Frazzi, Bruno Casali, Mauro Iori, Davide Nicoli, Caterina Mammi, Francesco Merli
Pages: 677-684
Published online on: 14 January 2011

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Promoter methylation in the PTCH gene in cervical epithelial cancer and ovarian cancer tissue as studied by eight novel Pyrosequencing® assays

Zarah M. Löf-Öhlin, Sonja Levanat, Maja Sabol, Bengt Sorbe, Torbjörn K. Nilsson
Pages: 685-692
Published online on: 03 January 2011

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Apoptosis and cell growth arrest in A375 human melanoma cells by diorganotin(IV) and triorganotin(IV) complexes of [meso-Tetra(4-sulfonatophenyl)porphine] manganese(III)chloride

Maria Assunta Costa, Francesca Zito, Maria Rita Emma, Lorenzo Pellerito, Tiziana Fiore, Claudia Pellerito, Giovanna Barbieri
Pages: 693-700
Published online on: 27 December 2010

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The chemosensitizing activity of inhibitors of glucosylceramide synthase is mediated primarily through modulation of P-gp function

Lilly Chai, Rajashree P. McLaren, Ann Byrne, Wei-Lien Chuang, Yinyin Huang, Michael R. Dufault, Joshua Pacheco, Shruti Madhiwalla, Xiaokui Zhang, Mindy Zhang, Beverly A. Teicher, Kara Carter, Seng H. Cheng, John P. Leonard, Yibin Xiang, Michael Vasconcelles, Mark A. Goldberg, Diane P. Copeland, Katherine W. Klinger, James Lillie, Stephen L. Madden, Yide A. Jiang
Pages: 701-711
Published online on: 24 December 2010

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β-hydroxy-β-methylbutyrate (HMB) attenuates muscle and body weight loss in experimental cancer cachexia

Zaira Aversa, Andrea Bonetto, Paola Costelli, Valerio Giacomo Minero, Fabio Penna, Francesco Maria Baccino, Simone Lucia, Filippo Rossi Fanelli, Maurizio Muscaritoli
Pages: 713-720
Published online on: 23 December 2010

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Novel therapeutic potential in targeting microtubules by nanoparticle albumin-bound paclitaxel in hepatocellular carcinoma

Qian Zhou, Arthur K.-K. Ching, Wilson K.-C. Leung, Carol Y.-Y. Szeto, Shuk-Mei Ho, Paul K.-S. Chan, Yun-Fei Yuan, Paul B.-S. Lai, Winnie Yeo, Nathalie Wong
Pages: 721-731
Published online on: 14 January 2011

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Downregulation of uPA/uPAR inhibits intermittent hypoxia-induced epithelial-mesenchymal transition (EMT) in DAOY and D283 medulloblastoma cells

Reshu Gupta, Chandramu Chetty, Praveen Bhoopathi, Sajani Lakka, Sanjeeva Mohanam, Jasti S. Rao, Dzung Η. Dinh
Pages: 733-744
Published online on: 22 December 2010

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Adenovirus-mediated Drosophila melanogaster deoxyribonucleoside kinase mutants combined with gemcitabine harbor a safe cancer treatment profile

Zhi Zhu, Shuai Ma, Lei Zhao, Zhe Sun, Anning He, Huimian Xu, Xinyu Zheng
Pages: 745-753
Published online on: 24 December 2010

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Circulating melanoma cells and survival in metastatic melanoma

C. Rao, T. Bui, M. Connelly, G. Doyle, I. Karydis, M. R. Middleton, G. Clack, M. Malone, F. A.W. Coumans, L.W. M.M. Terstappen
Pages: 755-760
Published online on: 03 January 2011

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Ganodermanontriol, a lanostanoid triterpene from Ganoderma lucidum, suppresses growth of colon cancer cells through ß-catenin signaling

Andrej Jedinak, Anita Thyagarajan-Sahu, Jiahua Jiang, Daniel Sliva
Pages: 761-767
Published online on: 11 January 2011

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Honokiol, a phytochemical from Magnolia spp., inhibits breast cancer cell migration by targeting nitric oxide and cyclooxygenase-2

Tripti Singh, Santosh K. Katiyar
Pages: 769-776
Published online on: 11 January 2011

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Article

PAR, a protein involved in the cell cycle, is functionally related to chromosomal passenger proteins

Micsunica Platica, Alin Ionescu, Elena Ivan, James F. Holland, John Mandeli, Ovidiu Platica
Pages: 777-785
Published online on: 11 January 2011

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The roles of AIF and Endo G in the apoptotic effects of benzyl isothiocyanate on DU 145 human prostate cancer cells via the mitochondrial signaling pathway

Kuo-Ching Liu, Ya-Ting Huang, Ping-Ping Wu, Bin-Chuan Ji, Jai-Sing Yang, Jiun-Long Yang, Tsan-Hung Chiu, Fu-Shin Chueh, Jing-Gung Chung
Pages: 787-796
Published online on: 30 December 2010

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Article

Differential roles of Src in transforming growth factor-ß regulation of growth arrest, epithelial-to-mesenchymal transition and cell migration in pancreatic ductal adenocarcinoma cells

Hendrik Ungefroren, Susanne Sebens, Stephanie Groth, Frank Gieseler, Fred Fändrich
Pages: 797-805
Published online on: 11 January 2011

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HDAC inhibitors downregulate MRP2 expression in multidrug resistant cancer cells: Implication for chemosensitization

Hanna Kim, Su-Nam Kim, Yeon-Suk Park, Nam Hyun Kim, Jeung Whan Han, Hoi Young Lee, Yong Kee Kim
Pages: 807-812
Published online on: 17 December 2010

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Genomic organization and localization of the NAD-dependent histone deacetylase gene sirtuin 3 (Sirt3) in the mouse

Ulrich Mahlknecht, Susanne Voelter-Mahlknecht
Pages: 813-822
Published online on: 15 December 2010

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Migration of renal tumor cells depends on dephosphorylation of Shc by PTEN

Elke Schneider, Romy Keppler, Dirk Prawitt, Christoph Steinwender, Frederik C. Roos, Joachim W. Thüroff, Ekkehart Lausch, Walburgis Brenner
Pages: 823-831
Published online on: 30 December 2010

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Quercetin inhibits a large panel of kinases implicated in cancer cell biology

Rainatou Boly, Thierry Gras, Touria Lamkami, Pierre Guissou, Didier Serteyn, Robert Kiss, Jacques Dubois
Pages: 833-842
Published online on: 27 December 2010

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Article

Differential forms of p53 in medulloblastoma primary tumors, cell lines and xenografts

Tzvetomira Philipova, Ninib Baryawno, Wolfgang Hartmann, Torsten Pietsch, Henrik Druid, John Inge Johnsen, Tomas J. Ekström
Pages: 843-849
Published online on: 23 December 2010

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PPARγ is functionally expressed in clear cell renal cell carcinoma

Nicolas Collet, Sandrine Théoleyre, Julie Rageul, Stéphanie Mottier, Florence Jouan, Nathalie Rioux-Leclercq, Patricia Fergelot, Jean-Jacques Patard, Damien Masson, Marc G. Denis
Pages: 851-857
Published online on: 28 December 2010

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Article

Epigenetic regulation of the potential tumor suppressor gene, hLHX6.1, in human cervical cancer

Samil Jung, Dongjun Jeong, Jinsun Kim, Lisha Yi, Keunhoe Koo, Jaehyouk Lee, Chang-Jin Kim, Chang-Hwan Kim, Sungwhan An, Young Yang, Jong-Seok Lim, Keun Il Kim, Myeong-Sok Lee
Pages: 859-869
Published online on: 14 January 2011

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Article

Vaccinia virus GLV-1h237 carrying a Walker A motif mutation of mouse Cdc6 protein enhances human breast tumor therapy in mouse xenografts

Elisabeth Hofmann, Friedrich Grummt, Aladar A. Szalay
Pages: 871-878
Published online on: 18 January 2011

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Article

Simvastatin modulates the adhesion and growth of hepatocellular carcinoma cells via decrease of integrin expression and ROCK

Borna Relja, Frank Meder, Minhong Wang, Roman Blaheta, Dirk Henrich, Ingo Marzi, Mark Lehnert
Pages: 879-885
Published online on: 28 December 2010

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Review Open Access

Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Multifaceted roles of miR‑124 in cancer: Molecular mechanisms and clinical prospects (Review)

Jun Guo, Yunyan Guo, Peiyang Chen, Wenyan Xiao, Yuxiang Tan, Zhiyong Wang, Yanxin Lu, Xupeng Yue
Article Number: 63
Published online on: 24 March 2026

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Hypoxia‑induced exosomal CAMTA1 promotes radio‑resistance in MDA‑MB‑231 cells by regulating NRG1 to mediate M2 macrophage polarization

Qian Li, Minghua Jiang, Biqing Zhu, Wei Wei, Lei Xia, Jian Huang, Han Gao, Mingyu Du
Article Number: 62
Published online on: 20 March 2026

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Correction Open Access

[Corrigendum] Epithelial protein lost in neoplasm‑α (EPLIN‑α) is a potential prognostic marker for the progression of epithelial ovarian cancer

Rong Liu, Tracey A. Martin, Nicola J. Jordan, Fiona Ruge, Lin Ye, Wen G. Jiang
Article Number: 61
Published online on: 18 March 2026

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Crosstalk between KRAS and miRNAs in pancreatic cancer: Opportunities for its diagnosis, prognosis and therapeutic intervention (Review)

Abdulaziz A. Aloliqi, Abdullah M. Alnuqaydan, Mohammad Alshebremi, Arshad Husain Rahmani, Amjad Ali Khan
Article Number: 60
Published online on: 18 March 2026

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Smoking promotes colorectal cancer via the CKAP2L/AREG axis

Shasha Wu, Feixiang Wu, Xiaoqing Li, Zhihang Jiang, Fuqiang Liu, Zheng Jiang
Article Number: 59
Published online on: 13 March 2026

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Diverse roles of SERPINE1 in regulating cellular proliferation and invasion

Wei Wang, Pengfei Zhao, Tian Wang, Weijing Wu, Jing Li, Qiang Huang, Jing Mo
Article Number: 58
Published online on: 13 March 2026

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Therapeutic implications of targeting cancer testis antigen MAGEA1 in cervical cancer

Ayoung Kim, Jina Kim, Woori Kwak, Kyumin Mo, Soohyun Choe, Minyeong Jeon, Jisun Lee, Jun-Won Yun, Hyunho Yoon
Article Number: 57
Published online on: 12 March 2026

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Review Open Access

Enolase 1: A paradigm of metabolic enzyme moonlighting in tumorigenesis (Review)

Xiaochen Ni, Mingsi Zhang, Kaiyuan Zhang, Chuhang Wang, Jianing Guo, Wei Fan, Linfeng Zheng, Tao Jiang, Guangji Zhang
Article Number: 56
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Article Number: 55
Published online on: 09 March 2026

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Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review)

Guirui Zhang, Yongmo Wu, Mingzhen Wei, Shupeng Huang, Qinghao Wang, Zhengyi Xie, Sisi Liu, Jin Wang
Article Number: 54
Published online on: 06 March 2026

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Retraction Open Access

[Retracted] Design, synthesis and preclinical evaluation of NRC‑AN‑019

Kompella Amala, A.K.S. Bhujanga Rao, Bharathi Gorantla, Christopher S.  Gondi, Jasti S. Rao
Article Number: 53
Published online on: 04 March 2026

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