Journal Articles

Novel strategies in the treatment of castration-resistant prostate cancer (Review)

Ilaria Marech, Angelo Vacca, Girolamo Ranieri, Antonio Gnoni, Franco Dammacco

Pages: 1313-1320 Published online on: 09 February 2012
Open Access

MEDI3617, a human anti-Angiopoietin 2 monoclonal antibody, inhibits angiogenesis and tumor growth in human tumor xenograft models

Ching Ching Leow, Karen Coffman, Ivan Inigo, Shannon Breen, Meggan Czapiga, Serguei Soukharev, Neill Gingles, Norman Peterson, Christine Fazenbaker, Rob Woods, Bahija Jallal, Sally-Ann Ricketts, Theresa Lavallee, Steve Coats, Yong Chang

Pages: 1321-1330 Published online on: 10 February 2012
Open Access

Improvement of replication fidelity by certain mesalazine derivatives

Clemens Honeder, Christoph Campregher, Bettina Zens, Theresa Scharl, Christoph Gasche

Pages: 1331-1338 Published online on: 21 February 2012
Open Access

ProstaCaid™ inhibits tumor growth in a xenograft model of human prostate cancer

Jiahua Jiang, Jagadish Loganathan, Isaac Eliaz, Colin Terry, George E. Sandusky, Daniel Sliva

Pages: 1339-1344 Published online on: 24 January 2012
Open Access

Nestin as a novel therapeutic target for pancreatic cancer via tumor angiogenesis

Kazuya Yamahatsu, Yoko Matsuda, Toshiyuki Ishiwata, Eiji Uchida, Zenya Naito

Pages: 1345-1357 Published online on: 13 January 2012
Open Access

Crucial cross-talk of interleukin-1β and progesterone in human choriocarcinoma

Elena Zachariades, Dionisis Mparmpakas, Peter Thomas, Mariann Rand-Weaver, Emmanouil Karteris

Pages: 1358-1364 Published online on: 27 January 2012
Open Access

Pathway simulations in common oncogenic drivers of leukemic and rhabdomyosarcoma cells: A systems biology approach

George I. Lambrou, Apostolos Zaravinos, Maria Adamaki, Demetrios  A. Spandidos, Fotini Tzortzatou-Stathopoulou, Spiros Vlachopoulos

Pages: 1365-1390 Published online on: 07 February 2012
Open Access

Involvement of p21waf1/cip1 expression in the cytotoxicity of the potent histone deacetylase inhibitor spiruchostatin B towards susceptible NALM-6 human B cell leukemia cells

Syu-Ichi Kanno, Naoyuki Maeda, Ayako Tomizawa, Shin Yomogida, Tadashi Katoh, Masaaki Ishikawa

Pages: 1391-1396 Published online on: 30 December 2011
Open Access

Expression profiles of Toll-like receptors in non-small cell lung cancer and idiopathic pulmonary fibrosis

Katerina D. Samara, Katerina M. Antoniou, Konstantinos Karagiannis, Georgios Margaritopoulos, Ismini Lasithiotaki, Eleni Koutala, Nikolaos M. Siafakas

Pages: 1397-1404 Published online on: 15 February 2012
Open Access

Influence of a 50 Hz magnetic field and of all-trans‑retinol on the proliferation of human cancer cell lines

María Ángeles Trillo, María Antonia Martínez, María  Antonia Cid, Jocelyne Leal, Alejandro Úbeda

Pages: 1405-1413 Published online on: 27 January 2012

Upregulated expression of ADAM12 is associated with progression of oral squamous cell carcinoma

Erika Uehara, Masashi Shiiba, Keiji Shinozuka, Kengo Saito, Yukinao Kouzu, Hirofumi Koike, Atsushi Kasamatsu, Yosuke Sakamoto, Katsunori Ogawara, Katsuhiro Uzawa, Hideki Tanzawa

Pages: 1414-1422 Published online on: 20 January 2012

Hypoxia and TP53 deficiency for induced pluripotent stem cell-like properties in gastrointestinal cancer

Hiromitsu Hoshino, Hiroaki Nagano, Naotsugu Haraguchi, Shimpei Nishikawa, Akira Tomokuni, Yoshihiro Kano, Takahito Fukusumi, Toshiyuki Saito, Miyuki Ozaki, Daisuke Sakai, Taroh Satoh, Hidetoshi Eguchi, Mitsugu Sekimoto, Yuichiro Doki, Masaki Mori, Hideshi Ishii

Pages: 1423-1430 Published online on: 24 January 2012

Blockade of TRPM8 activity reduces the invasion potential of oral squamous carcinoma cell lines

Yoshihiko Okamoto, Tsuyako Ohkubo, Tetsuro Ikebe, Jun Yamazaki

Pages: 1431-1440 Published online on: 20 January 2012

Significant induction of apoptosis in renal cell carcinoma cells transfected with cationic multilamellar liposomes containing the human interferon-β gene through activation of the intracellular type 1 interferon signal pathway

Natsuki Takaha, Hiroyuki Nakanishi, Yasunori Kimura, Fumiya Hongo, Kazumi Kamoi, Akihiro Kawauchi, Masaaki Mizuno, Jun Yoshida, Toshihiko Wakabayashi, Tsuneharu Miki

Pages: 1441-1446 Published online on: 16 February 2012

Characterization of a novel mouse monoclonal antibody, clone 1E8.33, highly specific for human procollagen 11A1, a tumor-associated stromal component

Marcos García-Ocaña, Fernando Vázquez, Carmen García-Pravia, Nelson Fuentes-Martínez, Primitiva Menéndez-Rodríguez, Florentino Fresno-Forcelledo, Luis Barneo-Serra, Jokin Del Amo-Iribarren, Laureano Simón-Buela, Juan R. De Los Toyos

Pages: 1447-1454 Published online on: 07 February 2012

Identification of genes potentially involved in bone metastasis by genome-wide gene expression profile analysis of non-small cell lung cancer in mice

Le Tan Dat, Taisuke Matsuo, Tetsuro Yoshimaru, Soji Kakiuchi, Hisatsugu Goto, Masaki Hanibuchi, Takuya Kuramoto, Yasuhiko Nishioka, Saburo Sone, Toyomasa Katagiri

Pages: 1455-1469 Published online on: 27 January 2012

Inhibition of cell viability by human IFN-β is mediated by microRNA-431

Takeshi Tanaka, Shigeru Sugaya, Kazuko Kita, Makoto Arai, Tatsuo Kanda, Katsunori Fujii, Fumio Imazeki, Katsuo Sugita, Osamu Yokosuka, Nobuo Suzuki

Pages: 1470-1476 Published online on: 24 January 2012

Down-regulation of miR-125a-3p in human gastric cancer and its clinicopathological significance

Yojiro Hashiguchi, Naohiro Nishida, Koshi Mimori, Tomoya Sudo, Fumiaki Tanaka, Kohei Shibata, Hideshi Ishii, Hidetaka Mochizuki, Kazuo Hase, Yuichiro Doki, Masaki Mori

Pages: 1477-1482 Published online on: 09 February 2012

The anti-obesity drug orlistat promotes sensitivity to TRAIL by two different pathways in hormone-refractory prostate cancer cells Corrigendum in /10.3892/ijo.2015.3265

Jun Fujiwara, Yoshihiro Sowa, Mano Horinaka, Makoto Koyama, Miki Wakada, Tsuneharu Miki, Toshiyuki Sakai

Pages: 1483-1491 Published online on: 02 February 2012

Personalized peptide vaccination in patients with refractory non-small cell lung cancer

Koichi Yoshiyama, Yasuhiro Terazaki, Satoko Matsueda, Shigeki Shichijo, Masanori Noguchi, Akira Yamada, Takashi Mine, Tetsuya Ioji, Kyogo Itoh, Kazuo Shirouzu, Tetsuro Sasada, Shinzo Takamori

Pages: 1492-1500 Published online on: 01 February 2012

Norcantharidin: A potential antiangiogenic agent for gallbladder cancers in vitro and in vivo

Jing-Tao Zhang, Yue-Zu Fan, Chun-Qiu Chen, Zhe-Ming Zhao, Wei Sun

Pages: 1501-1514 Published online on: 21 December 2011

Carboxyl-terminal modulator protein induces apoptosis by regulating mitochondrial function in lung cancer cells

Soon-Kyung Hwang, Arash Minai-Tehrani, Kyeong-Nam Yu, Seung-Hee Chang, Ji-Eun Kim, Kee-Ho Lee, Jongsun Park, George R. Beck , Myung-Haing Cho

Pages: 1515-1524 Published online on: 23 December 2011

A novel CD44v6 targeting antibody fragment with improved tumor-to-blood ratio

K. Sandström, A. K. Haylock, D. Spiegelberg, F. Qvarnström, K. Wester, M. Nestor

Pages: 1525-1532 Published online on: 01 February 2012

Change in gene expression profiles of secreted frizzled-related proteins (SFRPs) by sodium butyrate in gastric cancers: Induction of promoter demethylation and histone modification causing inhibition of Wnt signaling

Hyunsoo Shin, Jie-Hyun Kim, Yeo Song Lee, Yong Chan Lee

Pages: 1533-1542 Published online on: 10 January 2012

Millimeter wave treatment induces apoptosis via activation of the mitochondrial-dependent pathway in human osteosarcoma cells Retraction in /ijo/44/2/629

Guangwen Wu, Xuzheng Chen, Jun Peng, Qiaoyan Cai, Jinxia Ye, Huifeng Xu, Chunsong Zheng, Xihai Li, Hongzhi Ye, Xianxiang Liu

Pages: 1543-1552 Published online on: 12 January 2012

miR-10b promotes cell invasion through RhoC-AKT signaling pathway by targeting HOXD10 in gastric cancer

Zhuo Liu, Jiaming Zhu, Hong Cao, Hui Ren, Xuedong Fang

Pages: 1553-1560 Published online on: 24 January 2012

Expression analysis of Cdc42 in lung cancer and modulation of its expression by curcumin in lung cancer cell lines

Qing-Yong Chen, De-Min Jiao, Qing-Hua Yao, Jie Yan, Jia Song, Fang-Yuan Chen, Guo-Hua Lu, Jian-Ying Zhou

Pages: 1561-1568 Published online on: 17 January 2012

Pien Tze Huang inhibits tumor cell proliferation and promotes apoptosis via suppressing the STAT3 pathway in a colorectal cancer mouse model

Qunchuan Zhuang, Fei Hong, Aling Shen, Liangpu Zheng, Jianwei Zeng, Wei Lin, Youqin Chen, Thomas J. Sferra, Zhenfeng Hong, Jun Peng

Pages: 1569-1574 Published online on: 03 January 2012

Yin Yang-1 inhibits tumor cell growth and inhibits p21WAF1/Cip1 complex formation with cdk4 and cyclin D1

Hideto Ishii, Mark D. Hulett, Jian-Mei Li, Fernando S. Santiago, Christopher R. Parish, Levon M. Khachigian

Pages: 1575-1580 Published online on: 09 February 2012

Mucin production determines sensitivity to bortezomib and gemcitabine in pancreatic cancer cells

Thaddäus Till Wissniowski, Silke Meister, Eckhart G. Hahn, Joachim R. Kalden, Reinhard Voll, Matthias Ocker

Pages: 1581-1589 Published online on: 18 January 2012

Identification of prognostic biomarkers for response to radiotherapy by DNA microarray in nasopharyngeal carcinoma patients

Shu Yang, Jiaxin Chen, Yi Guo, Hui Lin, Zheng Zhang, Guosheng Feng, Yanrong Hao, Jinjian Cheng, Ping Liang, Kehe Chen, Hai Wu, Yao Li

Pages: 1590-1600 Published online on: 20 January 2012

Downregulation of heparanase by RNA interference inhibits invasion and tumorigenesis of hepatocellular cancer cells in vitro and in vivo

Zhen Xiong, Mu-Han Lü, Ya-Han Fan, Ya-Ling Cao, Chang-Jiang Hu, Yu-Yun Wu, Shu-Min Wang, Gang Luo, Dian-Chun Fang, Chuan Li, Shi-Ming Yang

Pages: 1601-1609 Published online on: 20 January 2012

Puerarin suppresses production of nitric oxide and inducible nitric oxide synthase in lipopolysaccharide-induced N9 microglial cells through regulating MAPK phosphorylation, O-GlcNAcylation and NF-κB translocation

Gao-Ming Zheng, Chao Yu, Zhu Yang

Pages: 1610-1618 Published online on: 13 January 2012

Sphingosine-1-phosphate receptor-3 signaling up-regulates epidermal growth factor receptor and enhances epidermal growth factor receptor-mediated carcinogenic activities in cultured lung adenocarcinoma cells

Andrew Hsu, Wenliang Zhang, Jen-Fu Lee, Jin An, Prasanna Ekambaram, Jingjing Liu, Kenneth V. Honn, Carolyn M. Klinge, Menq-Jer Lee

Pages: 1619-1626 Published online on: 16 February 2012

The p85α regulatory subunit of PI3K mediates cAMP-PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini

Pages: 1627-1635 Published online on: 21 February 2012

Aspirin enhances doxorubicin-induced apoptosis and reduces tumor growth in human hepatocellular carcinoma cells in vitro and in vivo

Mohammad Akbar Hossain, Dong Hwan Kim, Jung Yoon Jang, Yong Jung Kang, Jeong-Hyun Yoon, Jeon-Ok Moon, Hae Young Chung, Gi-Young Kim, Yung Hyun Choi, Bryan L. Copple, Nam Deuk Kim

Pages: 1636-1642 Published online on: 07 February 2012

Targeting cysteine-mediated dimerization of the MUC1-C oncoprotein in human cancer cells

Deepak Raina, Rehan Ahmad, Hasan Rajabi, Govind Panchamoorthy, Surender Kharbanda, Donald Kufe

Pages: 1643-1649 Published online on: 20 December 2011

Prognostic and diagnostic relevance of hypermethylated in cancer 1 (HIC1) CpG island methylation in renal cell carcinoma

H. Eggers, S. Steffens, A. Grosshennig, J. U. Becker, J. Hennenlotter, A. Stenzl, A. S. Merseburger, M. A. Kuczyk, J. Serth

Pages: 1650-1658 Published online on: 10 February 2012

Heat shock protein 90 is a promising target for effective growth inhibition of gastrointestinal neuroendocrine tumors

Christoph Gloesenkamp, Bianca Nitzsche, Alice R. Lim, Emmanuel Normant, Evan Vosburgh, Mark Schrader, Matthias Ocker, Hans Scherübl, Michael Höpfner

Pages: 1659-1667 Published online on: 10 January 2012

Properties of bcr-abl-transformed mouse 12B1 cells secreting interleukin-2 and granulocyte-macrophage colony-stimulating factor: I. Derivation, genetic stability, oncogenicity and immunogenicity

Martina Petráčková, Ruth Tachezy, Vladimír Vonka

Pages: 1668-1676 Published online on: 10 February 2012

Protein interactions with HER-family receptors can have different characteristics depending on the hosting cell line

Pavel Barta, Jennie Malmberg, Ludmila Melicharova, John Strandgård, Anna Orlova, Vladimir Tolmachev, Milan Laznicek, Karl Andersson

Pages: 1677-1682 Published online on: 19 December 2011

Geraniol induces cooperative interaction of apoptosis and autophagy to elicit cell death in PC-3 prostate cancer cells

Su-Hwa Kim, Eun-Jung Park, Chae Ryun Lee, Jung Nyeo Chun, Nam-Hyuk Cho, In-Gyu Kim, Sanghoon Lee, Tae Woo Kim, Hyun Ho Park, Insuk So, Ju-Hong Jeon

Pages: 1683-1690 Published online on: 23 December 2011

Sunitinib enhances antitumor effects against chemotherapy-resistant bladder cancer through suppression of ERK1/2 phosphorylation

Ario Takeuchi, Masatoshi Eto, Masaki Shiota, Katsunori Tatsugami, Akira Yokomizo, Kentaro Kuroiwa, Momoe Itsumi, Seiji Naito

Pages: 1691-1696 Published online on: 13 February 2012

Inhibition of migration and invasion of LNCaP human prostate carcinoma cells by cordycepin through inactivation of Akt

Jin-Woo Jeong, Cheng-Yun Jin, Cheol Park, Min Ho Han, Gi-Young Kim, Sung-Kwon Moon, Chan Gil Kim, Yong Kee Jeong, Wun-Jae Kim, Jae-Dong Lee, Yung Hyun Choi

Pages: 1697-1704 Published online on: 13 January 2012

Synergistic effects of suberoylanilide hydroxamic acid combined with cisplatin causing cell cycle arrest independent apoptosis in platinum-resistant ovarian cancer cells

Pei-Shi Ong, Xin-Qiao Wang, Hai-Shu Lin, Sui-Yung Chan, Paul C. Ho

Pages: 1705-1713 Published online on: 02 February 2012

ADAM17 targets MMP-2 and MMP-9 via EGFR-MEK-ERK pathway activation to promote prostate cancer cell invasion

Li-Jie Xiao, Ping Lin, Feng Lin, Xin Liu, Wei Qin, Hai-Feng Zou, Liang Guo, Wei Liu, Shu-Juan Wang, Xiao-Guang Yu

Pages: 1714-1724 Published online on: 23 December 2011
Journal Cover

Cover Legend PDF

May 2012
Volume 40 Issue 5

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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  • Journal Metrics
  • Impact Factor: 3.571
  • Ranked: 32/229 Oncology
    (total number of cites)
  • CiteScore: 3.57
  • CiteScore Rank: #77/321 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.928
  • SCImago Journal Rank (SJR): 1.16
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