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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2006 Volume 15 Issue 2

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Immunohistochemical localization of inhibin and activin subunits, activin receptors, and Smads in ovarian clear cell adenocarcinoma

Yasushi Mabuchi, Mareo Yamoto, Sawako Minami, Naohiko Umesaki
Pages: 291-296
Published online on: 01 February 2006

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Article

Chromosomal imbalances in malignant peripheral nerve sheath tumor detected by metaphase and microarray comparative genomic hybridization

Yasuko Nakagawa, Aki Yoshida, Kunihiko Numoto, Toshiyuki Kunisada, Daniel Wai, Norihide Ohata, Ken Takeda, Akira Kawai, Toshifumi Ozaki
Pages: 297-303
Published online on: 01 February 2006

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Article

Study of the expression of Tn antigen in different types of human breast cancer cells using VVA-B4 lectin

G. Konska, M. Guerry, F. Caldefie-Chezet, M. De Latour, J. Guillot
Pages: 305-310
Published online on: 01 February 2006

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Article

Matrilysin (MMP-7) degrades VE-cadherin and accelerates accumulation of beta-catenin in the nucleus of human umbilical vein endothelial cells

Yasushi Ichikawa, Takashi Ishikawa, Nobuyoshi Momiyama, Masako Kamiyama, Harumi Sakurada, Ryusei Matsuyama, Satoshi Hasegawa, Takashi Chishima, Yohei Hamaguchi, Shoichi Fujii, Shuji Saito, Kaori Kubota, Shingo Hasegawa, Hideyuki Ike, Shigeo Oki, Hiroshi Shimada
Pages: 311-315
Published online on: 01 February 2006

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Article

Prostate-specific antigen-reactive cytotoxic T lymphocyte precursors in colon cancer patients

Yi Wang, Mamoru Harada, Hirohisa Yano, Sachiko Ogasawara, Masahiro Tanaka, Akira Yamada, Kyogo Itoh
Pages: 317-321
Published online on: 01 February 2006

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Article

Reduced expression of p63 has prognostic implications for patients with esophageal squamous cell carcinoma

Yoshiaki Takahashi, Tsuyoshi Noguchi, Shinsuke Takeno, Yasuhiko Kimura, Masahiko Okubo, Katsunobu Kawahara
Pages: 323-328
Published online on: 01 February 2006

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Article

Antitumor effects of IDN5109 on head and neck squamous cell carcinoma

Daisuke Sano, Hideki Matsuda, Yukari Ishiguro, Goshi Nishimura, Mariko Kawakami, Mamoru Tsukuda
Pages: 329-334
Published online on: 01 February 2006

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Article

Effect of apoptosis and response of extracellular matrix proteins after chemotherapy application on human breast cancer cell spheroids

G. Oktem, S. Vatansever, S. Ayla, A. Uysal, S. Aktas, B. Karabulut, A. Bilir
Pages: 335-340
Published online on: 01 February 2006

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Article

Validation by RQ-PCR and flow cytometry of α-defensin1-3 (DEFA1-3) overexpression in relapsed and refractory acute lymphoblastic leukemia

Geertruy te Kronnie, Silvio Bicciato, Lisa Franceschini, Benedetta Accordi, Marta Campo Delliorto, Andrea Rinaldi, Andrea Pession, Elena Barisone, Valentino Conter, Franco Locatelli, Giuseppe Basso
Pages: 341-346
Published online on: 01 February 2006

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Article

Expression of the CD1a molecule in B- and T-lymphoproliferative skin conditions

Barbara Pigozzi, Matteo Bordignon, Anna Belloni Fortina, Giorgio Michelotto, Mauro Alaibac
Pages: 347-351
Published online on: 01 February 2006

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Article

Active (p)CrkL is overexpressed in human malignancies: Potential role as a surrogate parameter for therapeutic tyrosine kinase inhibition

Christian F. Singer, Gernot Hudelist, Wolfgang Lamm, Ruth Mueller, Claudia Handl, Ernst Kubista, Klaus Czerwenka
Pages: 353-359
Published online on: 01 February 2006

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Article

Antitumor activity of humanized monoclonal antibody against HM1.24 antigen in human myeloma xenograft models

Shigeto Kawai, Yasushi Yoshimura, Shin-ichiro Iida, Yasuko Kinoshita, Yasuo Koishihara, Shuji Ozaki, Toshio Matsumoto, Masaaki Kosaka, Hisafumi Yamada-Okabe
Pages: 361-367
Published online on: 01 February 2006

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Article

The preserved expression of neuropilin (NRP) 1 contributes to a better prognosis in colon cancer

Takashi Kamiya, Tsutomu Kawakami, Yoshiyuki Abe, Masatake Nishi, Noboru Onoda, Noriyuki Miyazaki, Yasuhisa Oida, Hitoshi Yamazaki, Yoshito Ueyama, Masato Nakamura
Pages: 369-373
Published online on: 01 February 2006

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Article

Corticotropin-releasing hormone receptor-1 in human endometrial cancer

Grazia Graziani, Gabriella Ferrandina, Giacomo Pozzoli, Matteo Vergati, Alessia Muzi, Francesco Legge, Lucio Tentori, Giovanni Scambia, Pierluigi Navarra
Pages: 375-379
Published online on: 01 February 2006

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Article

Isolation and characterization of human breast tumor-derived endothelial cells

Cristina Grange, Benedetta Bussolati, Stefania Bruno, Valentina Fonsato, Anna Sapino, Giovanni Camussi
Pages: 381-386
Published online on: 01 February 2006

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Article

Clinical significance of immunocytochemistry for PIK3CA as a carcinogenesis-related marker on liquid-based cytology in cervical intraepithelial neoplasia

Tomoko Goto, Masashi Takano, Hidenori Sasa, Hitoshi Tsuda, Kazuhiro Yamauchi, Yoshihiro Kikuchi
Pages: 387-391
Published online on: 01 February 2006

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Article

GnRH agonists and antagonists decrease the metastatic progression of human prostate cancer cell lines by inhibiting the plasminogen activator system

D. Dondi, C. Festuccia, M. Piccolella, M. Bologna, M. Motta
Pages: 393-400
Published online on: 01 February 2006

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Article

TGF-β1-induced cell growth arrest and partial differentiation is related to the suppression of Id1 in human hepatoma cells

Bazarragchaa Damdinsuren, Hiroaki Nagano, Motoi Kondo, Javzandulam Natsag, Hiroyuki Hanada, Masato Nakamura, Hiroshi Wada, Hitoshi Kato, Shigeru Marubashi, Atsushi Miyamoto, Yutaka Takeda, Koji Umeshita, Keizo Dono, Morito Monden
Pages: 401-408
Published online on: 01 February 2006

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Article

mHFE7A, a newly identified monoclonal antibody to Fas, induces apoptosis in human melanoma cells in vitro and delays the growth of melanoma xenotransplants

Kenichi Hiramoto, Madoka Inui, Takahiko Kamei, Kenya Okumura, Minoru Nakase, Toshiro Tagawa
Pages: 409-415
Published online on: 01 February 2006

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Article

In vitro effects on proliferation, apoptosis and colony inhibition in ER-dependent and ER-independent human breast cancer cells by selected mushroom species

Yu-Huan Gu, Jessica Leonard
Pages: 417-423
Published online on: 01 February 2006

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Article

Mib-1 proliferation index is an independent predictor of lymph node metastasis in invasive breast cancer: A prospective study on 675 patients

Daniele Marrelli, Enrico Pinto, Alessandro Neri, Tiziana Megha, Walter Gioffrè, Tommaso Cioppa, Giovanni De Marco, Alfonso De Stefano, Franco Roviello
Pages: 425-429
Published online on: 01 February 2006

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Article

Caffeine stimulates the proliferation of human lung adenocarcinoma cells and small airway epithelial cells via activation of PKA, CREB and ERK1/2

Hussein A.N. Al-Wadei, Takashi Takahashi, Hildegard M. Schuller
Pages: 431-435
Published online on: 01 February 2006

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Article

Lymphatic microvessel density using D2-40 is associated with nodal metastasis in non-small cell lung cancer

Iwao Takanami
Pages: 437-442
Published online on: 01 February 2006

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Article

Promoter CpG methylation of multiple genes in pituitary adenomas: frequent involvement of caspase-8

M. Josefa Bello, Jose M. De Campos, Alberto Isla, Cacilda Casartelli, Juan A. Rey
Pages: 443-448
Published online on: 01 February 2006

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Article

Tumor cell dissemination in colon cancer does not predict extrahepatic recurrence in patients undergoing surgery for hepatic metastases

Katja Schoppmeyer, Nils Frühauf, Karl Oldhafer, Siegfried Seeber, Sabine Kasimir-Bauer
Pages: 449-454
Published online on: 01 February 2006

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Article

Thymidine kinase 1: A proliferation marker for determining prognosis and monitoring the surgical outcome of primary bladder carcinoma patients

Jie Zhang, Quanan Jia, Shan Zou, Pingan Zhang, Xiaobing Zhang, Sven Skog, Pengcheng Luo, Wei Zhang, Qimin He
Pages: 455-461
Published online on: 01 February 2006

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Article

GL15 and U251 glioblastoma-derived human cell lines are peculiarly susceptible to induction of mitotic death by very low concentrations of okadaic acid

Emilia Castigli, Miriam Sciaccaluga, Gianluca Schiavoni, Flora Brozzi, Roberto Fabiani, Paolo Gorello, Gian Luigi Gianfranceschi
Pages: 463-470
Published online on: 01 February 2006

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Article

Selective cyclooxygenase-2 inhibitors inhibit growth and induce apoptosis of bladder cancer

Jason Gee, I-Ling Lee, David Jendiroba, Susan M. Fischer, H. Barton Grossman, Anita L. Sabichi
Pages: 471-477
Published online on: 01 February 2006

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Article

The morphological pathway for mouse forestomach cancer

George Kossoy, Herzl Ben-Hur, Asher Elhayany, David F. Schneider, Itshak Zusman
Pages: 479-483
Published online on: 01 February 2006

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Article

Involvement of interaction between Fractalkine and CX3CR1 in cytotoxicity of natural killer cells against tumor cells

Xiaojun Zhang, Haiming Wei, Hui Wang, Zhigang Tian
Pages: 485-488
Published online on: 01 February 2006

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Review

Histone deacetylase inhibitors: A novel target of anticancer therapy (Review)

Gregory Kouraklis, Stamos Theocharis
Pages: 489-494
Published online on: 01 February 2006

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Article

Radiofrequency ablation in palliative supportive care: Early clinical experience

Frédéric Marchal, Laurent Brunaud, Christophe Bazin, Hervé Boccacini, Philippe Henrot, Philippe Troufleau, Ivan Krakowski, Denis Regent
Pages: 495-499
Published online on: 01 February 2006

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Article

Down-regulation of MT1-MMP expression suppresses tumor cell invasion in metastatic human SW626 ovarian cancer cells

Mingfu Wu, Gang Xu, Ling Xi, Junchen Wei, Anping Song, Zhiqiang Han, Jianfeng Zhou, Shixuan Wang, Tao Zhu, Arli Zhang, Yunping Lu, Ding Ma
Pages: 501-505
Published online on: 01 February 2006

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Article

Aberrant methylation of EDNRB and p16 genes in hepatocellular carcinoma (HCC) in Taiwan

Li-Sung Hsu, Hsin-Chen Lee, Gar-Yang Chau, Pen-Hui Yin, Chin-Wen Chi, Wing Yiu Lui
Pages: 507-511
Published online on: 01 February 2006

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Journal Cover
September-2026 Volume 56 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Polyphyllin II inhibits thyroid cancer progression by targeting HRH1 and suppressing Wnt/β‑catenin signaling

Jianwei Sun, Haifeng Liang, Yan Zhang, Ding Ding, Qian Xiang, Mengyang Zheng, Pengyue Zhang
Article Number: 163
Published online on: 23 July 2026

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Multidimensional molecular mechanisms of drug resistance in breast cancer: Implications for clinical decision‑making and treatment strategies (Review)

Wenya Xu, Shiyao Kang, Shaochen Xin, Yanbin Wu, Yuan Zhao, Miaomiao Sheng
Article Number: 162
Published online on: 22 July 2026

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Review Open Access

XPO1: From basic research to clinical treatment (Review)

Changyan Yang, Jing Zhu, Xiang Zheng, Xiaochen Hou, Jiumei Zhao, Youfu Pan, Yu Tang
Article Number: 161
Published online on: 22 July 2026

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Retraction Open Access

[Retracted] Methylation and intratumoural heterogeneity of 14‑3‑3 σ in oral cancer

Ujjal Kumar Bhawal, Keiichi Tsukinoki, Tomonori Sasahira, Fuyuki Sato, Yusuke Mori, Noriko Muto, Masaru Sugiyama, Hiroki Kuniyasu
Article Number: 160
Published online on: 20 July 2026

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Article Open Access

M2‑TAM‑derived exosomal miR‑491‑3p modulates UBE2D3 and promotes the proliferation, migration and invasion of lung cancer cells

Qiang Zhang, Yungang Sun, Yu Zhuang, Shiwei Xu, Mengxu Yao, Siyang Jiao, Qi Wang, Feng Shao, Xiaoying Zhang
Article Number: 159
Published online on: 17 July 2026

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Correction Open Access

[Corrigendum] Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway

Qingkai Zhang, Xufeng Tao, Shilin Xia, Jialin Qu, Huiyi Song, Jianjun Liu, Hailong Li, Dong Shang
Article Number: 158
Published online on: 15 July 2026

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Article Open Access

TM6SF2 overexpression suppresses the proliferation and promotes apoptosis of human hepatocellular carcinoma cells

Ziyou Huai, Wanying Xue, Xinxiao Jin, Shiyu Peng, Wenqiang Xu, Shujing Li, Huanfeng Hao, Yuanyuan Wang
Article Number: 157
Published online on: 14 July 2026

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Correction Open Access

[Corrigendum] VDAC upregulation and αTAT1‑mediated α‑tubulin acetylation contribute to tanespimycin‑induced apoptosis in Calu‑1 cells

Qilin Wang, Xiangguo Liu
Article Number: 156
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells

Annamaria Spina, Luca Sorvillo, Emilio Chiosi, Antonietta Esposito, Francesca Di Maiolo, Luigi Sapio, Michele Caraglia, Silvio Naviglio
Article Number: 155
Published online on: 06 July 2026

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Article Open Access

Identification of RRM2 as a key regulator of malignant epithelial cells in gastric cancer through single‑cell transcriptomics

Xinzhen Cai, Yun He, Lili Kang, Dongli Zhou, Mengmeng Wang, Tianyu Ma
Article Number: 154
Published online on: 03 July 2026

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Article

Impact of WFDC2 on the biological functions of cervical cancer cells and the regulation of the ERK/NF‑κB signaling pathway

Yanping Zhang, Hongling Zou, Shufeng Deng, Lvling Zou, Mingzhu Xia, Limin Tao
Article Number: 153
Published online on: 01 July 2026

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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