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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2006 Volume 15 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Immunohistochemical localization of inhibin and activin subunits, activin receptors, and Smads in ovarian clear cell adenocarcinoma

Yasushi Mabuchi, Mareo Yamoto, Sawako Minami, Naohiko Umesaki
Pages: 291-296
Published online on: 01 February 2006

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Article

Chromosomal imbalances in malignant peripheral nerve sheath tumor detected by metaphase and microarray comparative genomic hybridization

Yasuko Nakagawa, Aki Yoshida, Kunihiko Numoto, Toshiyuki Kunisada, Daniel Wai, Norihide Ohata, Ken Takeda, Akira Kawai, Toshifumi Ozaki
Pages: 297-303
Published online on: 01 February 2006

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Article

Study of the expression of Tn antigen in different types of human breast cancer cells using VVA-B4 lectin

G. Konska, M. Guerry, F. Caldefie-Chezet, M. De Latour, J. Guillot
Pages: 305-310
Published online on: 01 February 2006

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Article

Matrilysin (MMP-7) degrades VE-cadherin and accelerates accumulation of beta-catenin in the nucleus of human umbilical vein endothelial cells

Yasushi Ichikawa, Takashi Ishikawa, Nobuyoshi Momiyama, Masako Kamiyama, Harumi Sakurada, Ryusei Matsuyama, Satoshi Hasegawa, Takashi Chishima, Yohei Hamaguchi, Shoichi Fujii, Shuji Saito, Kaori Kubota, Shingo Hasegawa, Hideyuki Ike, Shigeo Oki, Hiroshi Shimada
Pages: 311-315
Published online on: 01 February 2006

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Article

Prostate-specific antigen-reactive cytotoxic T lymphocyte precursors in colon cancer patients

Yi Wang, Mamoru Harada, Hirohisa Yano, Sachiko Ogasawara, Masahiro Tanaka, Akira Yamada, Kyogo Itoh
Pages: 317-321
Published online on: 01 February 2006

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Article

Reduced expression of p63 has prognostic implications for patients with esophageal squamous cell carcinoma

Yoshiaki Takahashi, Tsuyoshi Noguchi, Shinsuke Takeno, Yasuhiko Kimura, Masahiko Okubo, Katsunobu Kawahara
Pages: 323-328
Published online on: 01 February 2006

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Article

Antitumor effects of IDN5109 on head and neck squamous cell carcinoma

Daisuke Sano, Hideki Matsuda, Yukari Ishiguro, Goshi Nishimura, Mariko Kawakami, Mamoru Tsukuda
Pages: 329-334
Published online on: 01 February 2006

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Article

Effect of apoptosis and response of extracellular matrix proteins after chemotherapy application on human breast cancer cell spheroids

G. Oktem, S. Vatansever, S. Ayla, A. Uysal, S. Aktas, B. Karabulut, A. Bilir
Pages: 335-340
Published online on: 01 February 2006

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Article

Validation by RQ-PCR and flow cytometry of α-defensin1-3 (DEFA1-3) overexpression in relapsed and refractory acute lymphoblastic leukemia

Geertruy te Kronnie, Silvio Bicciato, Lisa Franceschini, Benedetta Accordi, Marta Campo Delliorto, Andrea Rinaldi, Andrea Pession, Elena Barisone, Valentino Conter, Franco Locatelli, Giuseppe Basso
Pages: 341-346
Published online on: 01 February 2006

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Article

Expression of the CD1a molecule in B- and T-lymphoproliferative skin conditions

Barbara Pigozzi, Matteo Bordignon, Anna Belloni Fortina, Giorgio Michelotto, Mauro Alaibac
Pages: 347-351
Published online on: 01 February 2006

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Article

Active (p)CrkL is overexpressed in human malignancies: Potential role as a surrogate parameter for therapeutic tyrosine kinase inhibition

Christian F. Singer, Gernot Hudelist, Wolfgang Lamm, Ruth Mueller, Claudia Handl, Ernst Kubista, Klaus Czerwenka
Pages: 353-359
Published online on: 01 February 2006

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Article

Antitumor activity of humanized monoclonal antibody against HM1.24 antigen in human myeloma xenograft models

Shigeto Kawai, Yasushi Yoshimura, Shin-ichiro Iida, Yasuko Kinoshita, Yasuo Koishihara, Shuji Ozaki, Toshio Matsumoto, Masaaki Kosaka, Hisafumi Yamada-Okabe
Pages: 361-367
Published online on: 01 February 2006

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Article

The preserved expression of neuropilin (NRP) 1 contributes to a better prognosis in colon cancer

Takashi Kamiya, Tsutomu Kawakami, Yoshiyuki Abe, Masatake Nishi, Noboru Onoda, Noriyuki Miyazaki, Yasuhisa Oida, Hitoshi Yamazaki, Yoshito Ueyama, Masato Nakamura
Pages: 369-373
Published online on: 01 February 2006

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Article

Corticotropin-releasing hormone receptor-1 in human endometrial cancer

Grazia Graziani, Gabriella Ferrandina, Giacomo Pozzoli, Matteo Vergati, Alessia Muzi, Francesco Legge, Lucio Tentori, Giovanni Scambia, Pierluigi Navarra
Pages: 375-379
Published online on: 01 February 2006

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Article

Isolation and characterization of human breast tumor-derived endothelial cells

Cristina Grange, Benedetta Bussolati, Stefania Bruno, Valentina Fonsato, Anna Sapino, Giovanni Camussi
Pages: 381-386
Published online on: 01 February 2006

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Article

Clinical significance of immunocytochemistry for PIK3CA as a carcinogenesis-related marker on liquid-based cytology in cervical intraepithelial neoplasia

Tomoko Goto, Masashi Takano, Hidenori Sasa, Hitoshi Tsuda, Kazuhiro Yamauchi, Yoshihiro Kikuchi
Pages: 387-391
Published online on: 01 February 2006

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Article

GnRH agonists and antagonists decrease the metastatic progression of human prostate cancer cell lines by inhibiting the plasminogen activator system

D. Dondi, C. Festuccia, M. Piccolella, M. Bologna, M. Motta
Pages: 393-400
Published online on: 01 February 2006

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Article

TGF-β1-induced cell growth arrest and partial differentiation is related to the suppression of Id1 in human hepatoma cells

Bazarragchaa Damdinsuren, Hiroaki Nagano, Motoi Kondo, Javzandulam Natsag, Hiroyuki Hanada, Masato Nakamura, Hiroshi Wada, Hitoshi Kato, Shigeru Marubashi, Atsushi Miyamoto, Yutaka Takeda, Koji Umeshita, Keizo Dono, Morito Monden
Pages: 401-408
Published online on: 01 February 2006

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Article

mHFE7A, a newly identified monoclonal antibody to Fas, induces apoptosis in human melanoma cells in vitro and delays the growth of melanoma xenotransplants

Kenichi Hiramoto, Madoka Inui, Takahiko Kamei, Kenya Okumura, Minoru Nakase, Toshiro Tagawa
Pages: 409-415
Published online on: 01 February 2006

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Article

In vitro effects on proliferation, apoptosis and colony inhibition in ER-dependent and ER-independent human breast cancer cells by selected mushroom species

Yu-Huan Gu, Jessica Leonard
Pages: 417-423
Published online on: 01 February 2006

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Article

Mib-1 proliferation index is an independent predictor of lymph node metastasis in invasive breast cancer: A prospective study on 675 patients

Daniele Marrelli, Enrico Pinto, Alessandro Neri, Tiziana Megha, Walter Gioffrè, Tommaso Cioppa, Giovanni De Marco, Alfonso De Stefano, Franco Roviello
Pages: 425-429
Published online on: 01 February 2006

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Article

Caffeine stimulates the proliferation of human lung adenocarcinoma cells and small airway epithelial cells via activation of PKA, CREB and ERK1/2

Hussein A.N. Al-Wadei, Takashi Takahashi, Hildegard M. Schuller
Pages: 431-435
Published online on: 01 February 2006

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Article

Lymphatic microvessel density using D2-40 is associated with nodal metastasis in non-small cell lung cancer

Iwao Takanami
Pages: 437-442
Published online on: 01 February 2006

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Article

Promoter CpG methylation of multiple genes in pituitary adenomas: frequent involvement of caspase-8

M. Josefa Bello, Jose M. De Campos, Alberto Isla, Cacilda Casartelli, Juan A. Rey
Pages: 443-448
Published online on: 01 February 2006

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Article

Tumor cell dissemination in colon cancer does not predict extrahepatic recurrence in patients undergoing surgery for hepatic metastases

Katja Schoppmeyer, Nils Frühauf, Karl Oldhafer, Siegfried Seeber, Sabine Kasimir-Bauer
Pages: 449-454
Published online on: 01 February 2006

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Article

Thymidine kinase 1: A proliferation marker for determining prognosis and monitoring the surgical outcome of primary bladder carcinoma patients

Jie Zhang, Quanan Jia, Shan Zou, Pingan Zhang, Xiaobing Zhang, Sven Skog, Pengcheng Luo, Wei Zhang, Qimin He
Pages: 455-461
Published online on: 01 February 2006

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Article

GL15 and U251 glioblastoma-derived human cell lines are peculiarly susceptible to induction of mitotic death by very low concentrations of okadaic acid

Emilia Castigli, Miriam Sciaccaluga, Gianluca Schiavoni, Flora Brozzi, Roberto Fabiani, Paolo Gorello, Gian Luigi Gianfranceschi
Pages: 463-470
Published online on: 01 February 2006

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Article

Selective cyclooxygenase-2 inhibitors inhibit growth and induce apoptosis of bladder cancer

Jason Gee, I-Ling Lee, David Jendiroba, Susan M. Fischer, H. Barton Grossman, Anita L. Sabichi
Pages: 471-477
Published online on: 01 February 2006

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Article

The morphological pathway for mouse forestomach cancer

George Kossoy, Herzl Ben-Hur, Asher Elhayany, David F. Schneider, Itshak Zusman
Pages: 479-483
Published online on: 01 February 2006

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Article

Involvement of interaction between Fractalkine and CX3CR1 in cytotoxicity of natural killer cells against tumor cells

Xiaojun Zhang, Haiming Wei, Hui Wang, Zhigang Tian
Pages: 485-488
Published online on: 01 February 2006

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Review

Histone deacetylase inhibitors: A novel target of anticancer therapy (Review)

Gregory Kouraklis, Stamos Theocharis
Pages: 489-494
Published online on: 01 February 2006

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Article

Radiofrequency ablation in palliative supportive care: Early clinical experience

Frédéric Marchal, Laurent Brunaud, Christophe Bazin, Hervé Boccacini, Philippe Henrot, Philippe Troufleau, Ivan Krakowski, Denis Regent
Pages: 495-499
Published online on: 01 February 2006

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Article

Down-regulation of MT1-MMP expression suppresses tumor cell invasion in metastatic human SW626 ovarian cancer cells

Mingfu Wu, Gang Xu, Ling Xi, Junchen Wei, Anping Song, Zhiqiang Han, Jianfeng Zhou, Shixuan Wang, Tao Zhu, Arli Zhang, Yunping Lu, Ding Ma
Pages: 501-505
Published online on: 01 February 2006

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Article

Aberrant methylation of EDNRB and p16 genes in hepatocellular carcinoma (HCC) in Taiwan

Li-Sung Hsu, Hsin-Chen Lee, Gar-Yang Chau, Pen-Hui Yin, Chin-Wen Chi, Wing Yiu Lui
Pages: 507-511
Published online on: 01 February 2006

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Exploring the role of disulfidptosis‑related signatures in immune microenvironment, prognosis and therapeutic strategies of cholangiocarcinoma

Yue Chen, Jun Wu, Danxia Zhu, Lu Jiang, Jian Wang, Dachuan Zhang, Wenting He
Article Number: 37
Published online on: 02 January 2026

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Correction Open Access

[Corrigendum] Isolinderalactone enhances the inhibition of SOCS3 on STAT3 activity by decreasing miR‑30c in breast cancer

Meng-Chi Yen, Ying-Chu Shih, Ya-Ling Hsu, En-Shyh Lin, Yi-Shiuan Lin, Eing-Mei Tsai, Ya-Wen Ho, Ming-Feng Hou, Po-Lin Kuo
Article Number: 36
Published online on: 22 December 2025

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Article Open Access

Hypoxia‑mediated Krebs von den Lungen‑6 expression in breast cancer: Implications for tumor invasion and metastasis

Taisei Ichihara, Yoshihiro Hayashi, Takuya Sato, Mitsuko Iguchi, Makoto Toi, Hironaga Satake, Ichiro Murakami
Article Number: 35
Published online on: 19 December 2025

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Retraction Open Access

[Retracted] β‑elemene decreases cell invasion by upregulating E‑cadherin expression in MCF‑7 human breast cancer cells

Xian Zhang, Yang Zhang, Yinghua Li
Article Number: 34
Published online on: 18 December 2025

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Review Open Access

Research progress on the regulation of ferroptosis in NPC (Review)

Shuai Bai, Yanjie Guo, Jingling Qiang, Qiangfang Dai, Yanling Yang
Article Number: 33
Published online on: 18 December 2025

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Retraction Open Access

[Retracted] Platelet‑derived growth factor BB mediates the glioma‑induced migration of bone marrow‑derived mesenchymal stem cells by promoting the expression of vascular cell adhesion molecule‑1 through the PI3K, P38 MAPK and NF‑κB pathways

Yi Hu, Peng Cheng, Jiang-Chun Ma, Yi-Xue Xue, Yun-Hui Liu
Article Number: 32
Published online on: 08 December 2025

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Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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