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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2007 Volume 18 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Early development of histiocytic sarcomas in p53 knockout mice treated with N-bis(2-hydroxypropyl)nitrosamine

Akihiro Hirata, Tetsuya Tsukamoto, Masami Yamamoto, Shinji Takasu, Hiroki Sakai, Hisayo Ban, Tokuma Yanai, Toshiaki Masegi, Lawrence A. Donehower, Masae Tatematsu
Pages: 755-761
Published online on: 01 October 2007

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Article

Chemotherapy in metastatic malignant triton tumor: Report on two cases

N. H. Thoennissen, C. Schliemann, U. Brunnberg, E. Schmidt, A. Staebler, L. Stegger, C. Bremer, C. Schleicher, R. M. Mesters, C. Müller-Tidow, W. E. Berdel
Pages: 763-767
Published online on: 01 October 2007

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Article

Expression profile of class I histone deacetylases in human cancer tissues

Masamune Nakagawa, Yoshinao Oda, Takashi Eguchi, Shin-Ichi Aishima, Takashi Yao, Fumihito Hosoi, Yuji Basaki, Mayumi Ono, Michihiko Kuwano, Masao Tanaka, Masazumi Tsuneyoshi
Pages: 769-774
Published online on: 01 October 2007

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Article

Enhancement of capecitabine efficacy by oxaliplatin in human colorectal and gastric cancer xenografts

Noriaki Sawada, Kumiko Kondoh, Kazushige Mori
Pages: 775-778
Published online on: 01 October 2007

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Article

Rapid genetic diagnosis with transcription-reverse transcription concerted reaction system for peritoneal recurrence and survival in colorectal cancer patients

Tamuro Hayama, Hisae Iinuma, Toshiaki Watanabe
Pages: 779-784
Published online on: 01 October 2007

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Article

Inhibition of tumor growth through suppression of angiogenesis by brain-specific angiogenesis inhibitor 1 gene transfer in murine renal cell carcinoma

Shigetaka Kudo, Ryuichiro Konda, Wataru Obara, Daisuke Kudo, Kenzaburo Tani, Yusuke Nakamura, Tomoaki Fujioka
Pages: 785-791
Published online on: 01 October 2007

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Article

Prognostic value of differential expression of Laminin-5 γ2 in oral squamous cell carcinomas: Correlation with survival

A. Gasparoni, M. Della Casa, L. Milillo, G. Lorenzini, C. Rubini, R. Urso, L. Lo Muzio
Pages: 793-800
Published online on: 01 October 2007

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Article

Combination therapy of interferon-α and 5-fluorouracil inhibits tumor angiogenesis in human hepatocellular carcinoma cells by regulating vascular endothelial growth factor and angiopoietins

Hiroshi Wada, Hiroaki Nagano, Hirofumi Yamamoto, Isao Arai, Hideo Ota, Masato Nakamura, Bazarragchaa Damdinsuren, Takehiro Noda, Shigeru Marubashi, Atsushi Miyamoto, Yutaka Takeda, Koji Umeshita, Yuichiro Doki, Keizo Dono, Shoji Nakamori, Masato Sakon, Morito Monden
Pages: 801-809
Published online on: 01 October 2007

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Article

Ascorbate (vitamin C) induces cell death through the apoptosis-inducing factor in human breast cancer cells

Seung-Woo Hong, Dong-Hoon Jin, Eun-Sil Hahm, Sei-Hyun Yim, Jong-Seok Lim, Keun-Il Kim, Young Yang, Soo-Suk Lee, Jae-Seung Kang, Wang-Jae Lee, Won-Keun Lee, Myeong-Sok Lee
Pages: 811-815
Published online on: 01 October 2007

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Article

Methylation and intratumoural heterogeneity of 14-3-3 σ in oral cancer

Ujjal Kumar Bhawal, Keiichi Tsukinoki, Tomonori Sasahira, Fuyuki Sato, Yusuke Mori, Noriko Muto, Masaru Sugiyama, Hiroki Kuniyasu
Pages: 817-824
Published online on: 01 October 2007

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Article

A peroxisome proliferator-activated receptor γ antagonist induces vimentin cleavage and inhibits invasion in high-grade hepatocellular carcinoma

Kyung Ryoul Kim, Ha Na Choi, Ho Jin Lee, Hyun A Baek, Ho Sung Park, Kyu Yun Jang, Myoung Ja Chung, Woo Sung Moon
Pages: 825-832
Published online on: 01 October 2007

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Article

Peroxisome proliferator-activated receptor α and γ ligands inhibit the growth of human ovarian cancer

Tatsuhiko Shigeto, Yoshihito Yokoyama, Bing Xin, Hideki Mizunuma
Pages: 833-840
Published online on: 01 October 2007

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Article

Expression of Myc target gene mina53 in subtypes of human lymphoma

Kwesi Teye, Nobuyuki Arima, Yasuhiro Nakamura, Kikuo Sakamoto, Eizaburo Sueoka, Hiroshi Kimura, Makoto Tsuneoka
Pages: 841-848
Published online on: 01 October 2007

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Article

Anti-tumor activity of Gastrodia elata Blume is closely associated with a GTP-Ras-dependent pathway

Jin-Chul Heo, Sang-Uk Woo, MinSik Son, Ja-Young Park, Won-Sik Choi, Kyu-Tae Chang, Sung-Uk Kim, Eun-Kyung Yoon, Yong-Hoon Kim, Heung Mook Shin, Sang-Han Lee
Pages: 849-853
Published online on: 01 October 2007

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Article

Expression of metalloproteinases and their tissue inhibitors in squamous cell laryngeal carcinoma

T. A. Christopoulos, N. Papageorgakopoulou, P. Ravazoula, N. S. Mastronikolis, T. A. Papadas, D. A. Theocharis, D. H. Vynios
Pages: 855-860
Published online on: 01 October 2007

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Article

Boron neuron capture therapy using epithermal neutrons for recurrent cancer in the oral cavity and cervical lymph node metastasis

Yasunori Ariyoshi, Shin-Ichi Miyatake, Yoshihiro Kimura, Takeshi Shimahara, Shinji Kawabata, Kenji Nagata, Minoru Suzuki, Akira Maruhashi, Koji Ono, Masashi Shimahara
Pages: 861-866
Published online on: 01 October 2007

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Article

Tumor suppressor Prdx1 is a prognostic factor in esophageal squamous cell carcinoma patients

Isamu Hoshino, Hisahiro Matsubara, Yasunori Akutsu, Takanori Nishimori, Yasuo Yoneyama, Kentaro Murakami, Haruhito Sakata, Kazuyuki Matsushita, Takenori Ochiai
Pages: 867-871
Published online on: 01 October 2007

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Article

Association of DNA-PK activity and radiation-induced NBS1 foci formation in lymphocytes with clinical malignancy in breast cancer patients

Masanori Someya, Koh-Ichi Sakata, Yoshihisa Matsumoto, Hiroshi Tauchi, Hideaki Narimatsu, Masato Hareyama
Pages: 873-878
Published online on: 01 October 2007

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Article

Expression of retinoid X receptor α is decreased in 3'-methyl-4-dimethylaminoazobenzene-induced hepatocellular carcinoma in rats

Nobuhiro Ando, Masahito Shimizu, Masataka Okuno, Rie Matsushima-Nishiwaki, Hisashi Tsurumi, Takuji Tanaka, Hisataka Moriwaki
Pages: 879-884
Published online on: 01 October 2007

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Article

Reduced expression of TANGO in colon and hepatocellular carcinomas

Stephanie Arndt, Anja K. Bosserhoff
Pages: 885-891
Published online on: 01 October 2007

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Article

The activity of Selol in multidrug-resistant and sensitive human leukemia cells

Piotr Suchocki, Irena Misiewicz, Katarzyna Skupinska, Karolina Waclawek, Zbigniew Fijalek, Teresa Kasprzycka-Guttman
Pages: 893-899
Published online on: 01 October 2007

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Article

Perfusion CT can predict the response to chemoradiation therapy and survival in esophageal squamous cell carcinoma: Initial clinical results

Koichi Hayano, Shinichi Okazumi, Kiyohiko Shuto, Hisahiro Matsubara, Hideaki Shimada, Yoshihiro Nabeya, Toshiki Kazama, Noriyuki Yanagawa, Takenori Ochiai
Pages: 901-908
Published online on: 01 October 2007

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Article

Osteopontin stimulates melanoma growth and lung metastasis through NIK/MEKK1-dependent MMP-9 activation pathways

Hema Rangaswami, Gopal C. Kundu
Pages: 909-915
Published online on: 01 October 2007

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Article

Comparative genomic hybridization, BRAF, RAS, RET, and oligo-array analysis in aneuploid papillary thyroid carcinomas

Raquel Rodrigues, Lúcia Roque, Carla Espadinha, António Pinto, Rita Domingues, Joana Dinis, Ana Catarino, Teresa Pereira, Valeriano Leite
Pages: 917-926
Published online on: 01 October 2007

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Article

The relationship between the down-regulation of DNA-PKcs or Ku70 and the chemosensitization in human cervical carcinoma cell line HeLa

Xiaoyu Tian, Gang Chen, Hui Xing, Danhui Weng, Yunhong Guo, Ding Ma
Pages: 927-932
Published online on: 01 October 2007

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Article

Evaluation of anti-VEGFR-3 specific scFv antibodies as potential therapeutic and diagnostic tools for tumor lymph-angiogenesis

Ann H.M. Zehnder-Fjällman, Cornelia Marty, Cornelia Halin, Alexander Hohn, Roger Schibli, Kurt Ballmer-Hofer, Reto A. Schwendener
Pages: 933-941
Published online on: 01 October 2007

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Article

Identification of differential expression of genes in hepatocellular carcinoma by suppression subtractive hybridization combined cDNA microarray

Yuefang Liu, Xiaojing Zhu, Jin Zhu, Shibing Liao, Qi Tang, Kaikun Liu, Xiaohong Guan, Jianping Zhang, Zhenqing Feng
Pages: 943-951
Published online on: 01 October 2007

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Article

Expression of transcription factor CREB1 in human breast cancer and its correlation with prognosis

Alok Chhabra, Herman Fernando, Gareth Watkins, Robert E. Mansel, Wen G. Jiang
Pages: 953-958
Published online on: 01 October 2007

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Article

Artificial intelligence for predicting recurrence-free probability of non-invasive high-grade urothelial bladder cell carcinoma

Tommaso Cai, Gloria Conti, Gabriella Nesi, Matteo Lorenzini, Nicola Mondaini, Riccardo Bartoletti
Pages: 959-964
Published online on: 01 October 2007

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Article

Impact of therapeutically induced reactive oxygen species and radical scavenging by α-tocopherol on tumor cell adhesion

Oliver Thews, Christine Lambert, Debra K. Kelleher, Hans K. Biesalski, Peter Vaupel, Juergen Frank
Pages: 965-971
Published online on: 01 October 2007

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Article

Inhibition of Fatty Acid Synthase (FASN) synergistically enhances the efficacy of 5-fluorouracil in breast carcinoma cells

Alejando Vazquez-Martin, Santiago Ropero, Joan Brunet, Ramon Colomer, Javier A. Menendez
Pages: 973-980
Published online on: 01 October 2007

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Article

Expression of ECRG4 is an independent prognostic factor for poor survival in patients with esophageal squamous cell carcinoma

Yoichiro Mori, Hideyuki Ishiguro, Yoshiyuki Kuwabara, Masahiro Kimura, Akira Mitsui, Horoki Kurehara, Ryota Mori, Keisuke Tomoda, Ryo Ogawa, Takeyasu Katada, Koshiro Harata, Yoshitaka Fujii
Pages: 981-985
Published online on: 01 October 2007

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Article

Copper efflux transporter (ATP7B) contributes to the acquisition of cisplatin-resistance in human oral squamous cell lines

Kunio Yoshizawa, Shinichi Nozaki, Hiroko Kitahara, Teruhisa Ohara, Koroku Kato, Shuichi Kawashiri, Etsuhide Yamamoto
Pages: 987-991
Published online on: 01 October 2007

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Article

Analysis of hepatitis C virus-specific CD8+ T-cells with HLA-A*24 tetramers during phlebotomy and interferon therapy for chronic hepatitis C

Kyosuke Kaji, Yasunari Nakamoto, Shuichi Kaneko
Pages: 993-998
Published online on: 01 October 2007

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Article

Effects of the CDK-inhibitor CYC202 on p38 MAPK, ERK1/2 and c-Myc activities in papillomavirus type 16 E6- and E7-transformed human keratinocytes

Ganka N. Atanasova, Antonia R. Isaeva, Nikolai Zhelev, Yves Poumay, Vanyo I. Mitev
Pages: 999-1005
Published online on: 01 October 2007

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Article

Loss of heterozygosity on chromosome 10q23 and mutation of the phosphatase and tensin homolog deleted from chromosome 10 tumor suppressor gene in Korean hepatocellular carcinoma patients

Jei-Jun Bae, Jin-Woo Rho, Tae-Jin Lee, Sung-Su Yun, Hong-Jin Kim, Joon-Hyuk Choi, Daewon Jeong, Byeong-Churl Jang, Tae-Yoon Lee
Pages: 1007-1013
Published online on: 01 October 2007

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Article

Inhibitory effects of retinoic acid and IIF on growth, migration and invasiveness in the U87MG human glioblastoma cell line

A. Papi, G. Bartolini, K. Ammar, F. Guerra, A. M. Ferreri, P. Rocchi, M. Orlandi
Pages: 1015-1021
Published online on: 01 October 2007

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Article

Prognosis of small bowel adenocarcinoma treated with Mayo or Xelox regimen: A matched case-control study from a database of 581 patients with colorectal cancer

Jacob Thomsen Lønborg, Adam Vilmar, David Mård, Søren Astrup Jensen, Jens Benn Sørensen
Pages: 1023-1029
Published online on: 01 October 2007

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Article

Interferon-α-induced apoptosis via tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-dependent and -independent manner

Noriko Yanase, Yuki Kanetaka, Junichiro Mizuguchi
Pages: 1031-1038
Published online on: 01 October 2007

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Article

IFN-α competes with TNF-α for STAT-1α; molecular basis for immune escape of human colon adenocarcinoma COLO 205 cells

Beata Pajak, Arkadiusz Orzechowski
Pages: 1039-1045
Published online on: 01 October 2007

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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