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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2008 Volume 19 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Phenoxazine derivative, 2-amino-4,4α-dihydro-4α,7-dimethyl-3H-phenoxazine-3-one suppresses growth of human retinoblastoma cell line Y79 in vitro and in vivo

Keisuke Kimura, Yoshihiko Usui, Takaaki Hattori, Naohiko Yamakawa, Hiroshi Goto, Masahiko Usui, Shinya Okada, Ken Shirato, Akio Tomoda
Pages: 3-10
Published online on: 01 January 2008

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Article

Preventive effect of fermented brown rice and rice bran on N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats

Hiroyuki Tomita, Toshiya Kuno, Yasuhiro Yamada, Takeru Oyama, Nami Asano, Yasuo Miyazaki, Seiji Baba, Ayako Taguchi, Akira Hara, Teruaki Iwasaki, Hiroshi Kobayashi, Hideki Mori
Pages: 11-15
Published online on: 01 January 2008

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Article

Oral paclitaxel chemotherapy for brain tumors: Ideal combination treatment of paclitaxel and P-glycoprotein inhibitor

Kyeung Min Joo, Kwan Park, Doo-Sik Kong, Sang Yong Song, Mi Hyun Kim, Gwan Sun Lee, Maeng Sup Kim, Do-Hyun Nam
Pages: 17-23
Published online on: 01 January 2008

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Article

Low claudin expression is associated with high Gleason grade in prostate adenocarcinoma

P. Väre, I. Loikkanen, P. Hirvikoski, M. H. Vaarala, Y. Soini
Pages: 25-31
Published online on: 01 January 2008

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Article

Decreased expression of SOCS-3 mRNA in breast cancer with lymph node metastasis

Tsuyoshi Nakagawa, Satoru Iida, Takayuki Osanai, Hiroyuki Uetake, Tomoyuki Aruga, Youichi Toriya, Yoko Takagi, Hiroshi Kawachi, Kenichi Sugihara
Pages: 33-39
Published online on: 01 January 2008

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Article

Fhit, Mlh1, P53 and phenotypic expression in the early stage of colorectal neoplasms

Akiko Yasugi, Kazuo Yashima, Akihito Hara, Masaharu Koda, Koichiro Kawaguchi, Kenichi Harada, Hironobu Andachi, Yoshikazu Murawaki
Pages: 41-47
Published online on: 01 January 2008

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Article

The abnormalities in the p53/p21WAF1 pathway have a significant role in the pathogenesis and progression of gastrointestinal stromal tumors

Yeh-Pin Chou, Jui-Wei Lin, Chih-Chi Wang, Yi-Chun Chiu, Chao-Cheng Huang, Seng-Kee Chuah, Ming-Hong Tai, Li-Na Yi, Chuan-Mo Lee, Chi-Sin Changchien, Tsung-Hui Hu
Pages: 49-56
Published online on: 01 January 2008

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Article

Potential for HER-2/neu molecular targeted therapy for invasive bladder carcinoma: Comparative study of immunohistochemistry and fluorescent in situ hybridization

Hiroyuki Matsubara, Yoshiaki Yamada, Katsuya Naruse, Kogenta Nakamura, Shigeyuki Aoki, Tomohiro Taki, Motoi Tobiume, Kenji Zennami, Remi Katsuda, Nobuaki Honda
Pages: 57-63
Published online on: 01 January 2008

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Article

Involvement of EGFR in the response of squamous cell carcinoma of the head and neck cell lines to gefitinib

Takahide Taguchi, Mamoru Tsukuda, Yukari Imagawa-Ishiguro, Yasumasa Kato, Daisuke Sano
Pages: 65-71
Published online on: 01 January 2008

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Article

Hyperthermic CO2 pneumoperitoneum induces apoptosis in human colon cancer cells through Bax-associated mitochondrial pathway

Yuanfei Peng, Minhua Zheng, Bo Feng, Xuehua Chen, Beiqin Yu, Aiguo Lu, Minliang Wang, Jianwen Li, Junjun Ma, Lie Xu
Pages: 73-79
Published online on: 01 January 2008

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Article

Significance of the glycolytic pathway and glycolysis related-genes in tumorigenesis of human colorectal cancers

Ching-Sheng Yeh, Jaw-Yuan Wang, Fu-Yen Chung, Su-Chen Lee, Ming-Yii Huang, Chia-Wei Kuo, Ming-Je Yang, Shiu-Ru Lin
Pages: 81-91
Published online on: 01 January 2008

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Article

Cell cycle arrest and lytic induction of EBV-transformed B lymphoblastoid cells by a histone deacetylase inhibitor, Trichostatin A

J. S. Seo, N. Y. Cho, H. R. Kim, T. Tsurumi, Y. S. Jang, W. K. Lee, S. K. Lee
Pages: 93-98
Published online on: 01 January 2008

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Article

Relationship between decreased expression of squamous cell carcinoma antigen 2 and E-cadherin in primary cervical cancer lesions and lymph node metastasis

Akihiro Murakami, Tatsushi Nakagawa, Chikako Fukushima, Mayumi Torii, Kotaro Sueoka, Shugo Nawata, Osamu Takeda, Hitoshi Ishikawa, Norihiro Sugino
Pages: 99-104
Published online on: 01 January 2008

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Article

Amphiregulin and epiregulin expression in neoplastic and inflammatory lesions in the colon

Takashi Nishimura, Akira Andoh, Osamu Inatomi, Makoto Shioya, Yuhki Yagi, Tomoyuki Tsujikawa, Yoshihide Fujiyama
Pages: 105-110
Published online on: 01 January 2008

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Article

Expression of hypoxia inducible factor-1α (HIF-1α) and glucose transporter-1 (GLUT-1) in ovarian adenocarcinomas: Difference in hypoxic status depending on histological character

Masanori Yasuda, Masaki Miyazawa, Mariko Fujita, Hiroshi Kajiwara, Tetsuji Iida, Takeshi Hirasawa, Toshinari Muramatsu, Masaru Murakami, Mikio Mikami, Kaoru Saitoh, Michio Shimizu, Susumu Takekoshi, R. Yoshiyuki Osamura
Pages: 111-116
Published online on: 01 January 2008

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Article

Hepatocyte growth factor induces anoikis resistance by up-regulation of cyclooxygenase-2 expression in uterine endometrial cancer cells

Seiji Kanayama, Yoshihiko Yamada, Ryuji Kawaguchi, Yoriko Tsuji, Shoji Haruta, Hiroshi Kobayashi
Pages: 117-122
Published online on: 01 January 2008

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Article

Ether lipid 1-O-octadecyl-2-O-methyl-3-glycero-phosphocholine inhibits cell-cell adhesion through translocation and clustering of E-cadherin and episialin in membrane microdomains

Severine Van Slambrouck, John Hilkens, Wim F.A. Steelant
Pages: 123-128
Published online on: 01 January 2008

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Article

Overexpression of papillomavirus binding factor in Ewing's sarcoma family of tumors conferring poor prognosis

Hiroki Yabe, Tomohide Tsukahara, Satoshi Kawaguchi, Takuro Wada, Noriyuki Sato, Hideo Morioka, Hiroo Yabe
Pages: 129-134
Published online on: 01 January 2008

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Article

Comprehensive analysis of time- and dose-dependent patterns of gene expression in a human mesenchymal stem cell line exposed to low-dose ionizing radiation

Young-Woo Jin, Young-Ji Na, Young-Ju Lee, Sungkwan An, Jung Eun Lee, Meeseon Jung, Heesun Kim, Seon Young Nam, Cha Soon Kim, Kwang Hee Yang, Seung Up Kim, Woo Kyung Kim, Woong-Yang Park, Keun-Young Yoo, Chong Soon Kim, Ju Han Kim
Pages: 135-144
Published online on: 01 January 2008

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Article

Differential involvement of mitochondria during ursolic acid-induced apoptotic process in HaCaT and M4Beu cells

Raphaël Emmanuel Duval, Pierre-Olivier Harmand, Chantal Jayat-Vignoles, Jeanne Cook-Moreau, Aline Pinon, Christiane Delage, Alain Simon
Pages: 145-149
Published online on: 01 January 2008

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Article

Increased expression of EphA2 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients

Lin-Fang Wang, Emmanouil Fokas, Michael Bieker, Frank Rose, Peter Rexin, Yuan Zhu, Axel Pagenstecher, Rita Engenhart-Cabillic, Han-Xiang An
Pages: 151-156
Published online on: 01 January 2008

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Article

Loss of ONECUT1 expression in human pancreatic cancer cells

Xiaohua Jiang, Weiwei Zhang, Hany Kayed, Pan Zheng, Nathalia A. Giese, Helmut Friess, Jörg Kleeff
Pages: 157-163
Published online on: 01 January 2008

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Article

Cell adhesion proteins altered by 17β estradiol and parathion in breast epithelial cells

G. M. Calaf, D. Roy
Pages: 165-169
Published online on: 01 January 2008

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Article

The association of vascular endothelial growth factor receptor-1 with the risk of cancer progression following radical prostatectomy

Kaili Mao, Philippe Camparo, Cecile Badoual, Michaël Peyromaure, Nicolas Barry Delongchamps, Annick Vieillefond, Anh-Tuan Dinh-Xuan
Pages: 171-175
Published online on: 01 January 2008

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Article

Sp1 is involved in 8-chloro-adenosine-upregulated death receptor 5 expression in human hepatoma cells

Minmin Sun, Jinchun Zhang, Shilian Liu, Yanxin Liu, Dexian Zheng
Pages: 177-185
Published online on: 01 January 2008

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Article

The ability of coumarin-, flavanon- and flavonol-analogues of flavone acetic acid to stimulate human monocytes

Mariagnese Barbera, Anna Caputo, Antonella Zampiron, Silvia Gobbi, Angela Rampa, Alessandra Bisi, Maria Carrara
Pages: 187-196
Published online on: 01 January 2008

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Article

Helicobacter pylori infection is an independent risk factor for Runx3 methylation in gastric cancer

Yoshihiko Kitajima, Kazuma Ohtaka, Mayumi Mitsuno, Masayuki Tanaka, Seiji Sato, Yuji Nakafusa, Kohji Miyazaki
Pages: 197-202
Published online on: 01 January 2008

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Article

Wnt1 overexpression associated with tumor proliferation and a poor prognosis in non-small cell lung cancer patients

Takashi Nakashima, Dage Liu, Jun Nakano, Shinya Ishikawa, Hiroyasu Yokomise, Masaki Ueno, Kyuichi Kadota, Cheng-Long Huang
Pages: 203-209
Published online on: 01 January 2008

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Article

The influence of promoter polymorphism of nuclear factor-erythroid 2-related factor 2 gene on the aberrant DNA methylation in gastric epithelium

Tomiyasu Arisawa, Tomomitsu Tahara, Tomoyuki Shibata, Mitsuo Nagasaka, Masakatsu Nakamura, Yoshio Kamiya, Hiroshi Fujita, Daisuke Yoshioka, Yuko Arima, Masaaki Okubo, Ichiro Hirata, Hiroshi Nakano
Pages: 211-216
Published online on: 01 January 2008

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Article

Gene expression and promoter polymorphisms of DNA methyltransferase 3B in nasopharyngeal carcinomas in Taiwanese people: A case-control study

Kai-Ping Chang, Sheng-Po Hao, Ngan-Ming Tsang, Yu-Liang Chang, Ming-Huei Cheng, Chun-Ting Liu, Yun-Shien Lee, Chia-Lung Tsai, Ta-Jen Lee, Tzu-Hao Wang, Chi-Neu Tsai
Pages: 217-222
Published online on: 01 January 2008

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Article

Functional promoter polymorphisms of the macrophage migration inhibitory factor gene in gastric carcinogenesis

Tomiyasu Arisawa, Tomomitsu Tahara, Tomoyuki Shibata, Mitsuo Nagasaka, Masakatsu Nakamura, Yoshio Kamiya, Hiroshi Fujita, Daisuke Yoshioka, Yuko Arima, Masaaki Okubo, Ichiro Hirata, Hiroshi Nakano, Vidal De la Cruz
Pages: 223-228
Published online on: 01 January 2008

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Article

A peptide derived from alpha-fetoprotein inhibits the proliferation induced by estradiol in mammary tumor cells in culture

Walter D. Sierralta, Maria J. Epuñan, José M. Reyes, Luis E. Valladares, Thomas T. Andersen, James A. Bennett, Herbert I. Jacobson, Ana M. Pino
Pages: 229-235
Published online on: 01 January 2008

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Article

CD1c+ and CD303+ dendritic cells in peripheral blood, lymph nodes and tumor tissue of patients with non-small cell lung cancer

Jacek Tabarkiewicz, Pawel Rybojad, Andrzej Jablonka, Jacek Rolinski
Pages: 237-243
Published online on: 01 January 2008

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Article

Tissue-dependent and -independent gene expression changes in metastatic colon cancer

William H. Gmeiner, Gary M. Hellmann, Perry Shen
Pages: 245-251
Published online on: 01 January 2008

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Article

Effects of the PPARγ agonist GW1929 on muscle wasting in tumour-bearing mice

Rodrigo Moore-Carrasco, Maite Figueras, Elisabet Ametller, Francisco J. López-Soriano, Josep M. Argilés, Sílvia Busquets
Pages: 253-256
Published online on: 01 January 2008

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Article

Validation of biomarkers associated with 5-fluorouracil and thymidylate synthase in colorectal cancer

Yaguang Xi, Andrea Formentini, Go Nakajima, Marko Kornmann, Jingfang Ju
Pages: 257-262
Published online on: 01 January 2008

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Article

BRCA1 and BRCA2 point mutations and large rearrangements in breast and ovarian cancer families in Northern Poland

Magdalena Ratajska, Izabela Brozek, Elzbieta Senkus-Konefka, Jacek Jassem, Magdalena Stepnowska, Grazia Palomba, Marina Pisano, Milena Casula, Giuseppe Palmieri, Ake Borg, Janusz Limon
Pages: 263-268
Published online on: 01 January 2008

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Article

Transcriptional regulation of the COX-2 expression by nitric oxide in colon cancer cell lines

Qiang Liu, Hiroyasu Inoue, Ratha Mahendran
Pages: 269-274
Published online on: 01 January 2008

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Article

Diallyl disulfide induces reversible G2/M phase arrest on a p53-independent mechanism in human colon cancer HCT-116 cells

Hong Jae Jo, Ju Dong Song, Kang Mi Kim, Yong Hoon Cho, Ki Hyung Kim, Young Chul Park
Pages: 275-280
Published online on: 01 January 2008

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Article

Radio-activation of hTERT promoter in larynx squamous carcinoma cells: An ‘indirected-activator’ strategy in radio-gene-therapy

Zheng-Kai Liao, Fu-Xiang Zhou, Zhi-Guo Luo, Wen-Jie Zhang, Jie Xiong, Jie Bao, Guang Han, Ming-Sheng Zhang, Cong-Hua Xie, Yun-Feng Zhou
Pages: 281-286
Published online on: 01 January 2008

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Article

Differences in proportion and dynamics of recipient hematopoiesis following hematopoietic cell transplantation in CML and IMF

Udo Siebolts, Jürgen Thiele, Thomas Zander, Markus Ditschkowski, Dietrich W. Beelen, Nicolaus Kröger, Boris Fehse, Claudia Wickenhauser
Pages: 287-292
Published online on: 01 January 2008

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

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