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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2009 Volume 22 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Targeting of the BRAF gene in papillary thyroid carcinoma (Review)

Yaqiong Li, Misa Nakamura, Kennichi Kakudo
Pages: 671-681
Published online on: 01 October 2009

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Article

Epidermal growth factor receptor and K-RAS mutations in 411 lung adenocarcinoma: A population-based prospective study

Laura Boldrini, Greta Alì, Silvia Gisfredi, Silvia Ursino, Editta Baldini, Franca Melfi, Marco Lucchi, Camilla E. Comin, Cristina Maddau, Carmelo Tibaldi, Tiziano Camacci, Adele Servadio, Alfredo Mussi, Gabriella Fontanini
Pages: 683-691
Published online on: 01 October 2009

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Article

Hypoxia-inducible factor-1α expression predicts the response to 5-fluorouracil-based adjuvant chemotherapy in advanced gastric cancer

Jun Nakamura, Yoshihiko Kitajima, Keita Kai, Mayumi Mitsuno, Takao Ide, Kazuyoshi Hashiguchi, Masatsugu Hiraki, Kohji Miyazaki
Pages: 693-699
Published online on: 01 October 2009

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Article

Combination treatment of Cetuximab and photodynamic therapy in SNU-1041 squamous cancer cell line

Sun Gon Kim, Ji Won Hong, Sung Hyun Boo, Myung Gu Kim, Kang Dae Lee, Jin Chul Ahn, Hee Jun Hwang, Jang-In Shin, Sang Joon Lee, Jang Keun Oh, Phil Sang Chung
Pages: 701-708
Published online on: 01 October 2009

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Article

Elevated CD133, but not VEGF or EGFR, as a predictive marker of distant recurrence after preoperative chemoradiotherapy in rectal cancer

Hiromi Yasuda, Koji Tanaka, Susumu Saigusa, Yuji Toiyama, Yuhki Koike, Yoshinaga Okugawa, Takeshi Yokoe, Aya Kawamoto, Yasuhiro Inoue, Chikao Miki, Masato Kusunoki
Pages: 709-717
Published online on: 01 October 2009

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Article

S-1 mediates the inhibition of lymph node metastasis in oral cancer cells

Hana Sato, Masashi Hatori, Yuriko Ando, Yuji Kurihara, Sayaka Takayama, Tatsuo Shirota, Tetsuhiko Tachikawa, Satoru Shintani
Pages: 719-724
Published online on: 01 October 2009

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Article Open Access

A scoring system for histopathologic and immunohistochemical evaluations of uterine leiomyosarcomas

Chika Yoshida, Tomoyuki Ichimura, Naoki Kawamura, Akemi Nakano, Mari Kasai, Toshiyuki Sumi, Osamu Ishiko
Pages: 725-731
Published online on: 01 October 2009

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Article

Aberrant expression of class III β-tubulin in basal cell carcinoma of the skin

Mitsuaki Ishida, Ryoji Kushima, Hidetoshi Okabe
Pages: 733-737
Published online on: 01 October 2009

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Article Open Access

Novel anti-cancer compounds: Structure-based discovery of chemical chaperons for p53

Yumiko Okuda, Hironori K. Nakamura, Kazuo Kuwata
Pages: 739-744
Published online on: 01 October 2009

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Article

CD44v6, MMP-7 and nuclear Cdx2 are significant biomarkers for prediction of lymph node metastasis in primary gastric cancer

Hirokazu Okayama, Kensuke Kumamoto, Katsuharu Saitou, Suguru Hayase, Yasuhide Kofunato, Yu Sato, Kotaro Miyamoto, Izumi Nakamura, Shinji Ohki, Kouji Sekikawa, Seiichi Takenoshita
Pages: 745-755
Published online on: 01 October 2009

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Article

PTEN expression and mutation in colorectal carcinomas

Xiao-Han Li, Hua-Chuan Zheng, Hiroyuki Takahashi, Shinji Masuda, Xiang-Hong Yang, Yasuo Takano
Pages: 757-764
Published online on: 01 October 2009

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Article

Enhanced radiosensitivity of SW480 cells via TRAIL up-regulation mediated by Egr-1 promoter

Y. Hu, W. Ouyang, F. Wu, C. H. Cao, K. Wang, Z. K. Liao, Y. H. Zhong, F. X. Zhou, S. Q. Liu, L. Xia, Y. F. Zhou, C. H. Xie
Pages: 765-771
Published online on: 01 October 2009

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Article

Promoter methylation and expression analysis of MGMT in advanced pediatric brain tumors

Iacopo Sardi, Valentina Cetica, Maura Massimino, Anna Maria Buccoliero, Laura Giunti, Lorenzo Genitori, Maurizio Aricò
Pages: 773-779
Published online on: 01 October 2009

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Article

Effect of CD133/prominin-1 antisense oligodeoxynucleotide on in vitro growth characteristics of Huh-7 human hepatocarcinoma cells and U251 human glioma cells

Jie Yao, Tao Zhang, Jinghua Ren, Minxia Yu, Gang Wu
Pages: 781-787
Published online on: 01 October 2009

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Article

Ninein-like protein is overexpressed in head and neck squamous cell carcinoma and contributes to cancer growth and resistance to apoptosis

Linlin Yu, Yongmei Song, Qiuhang Zhang, Qimin Zhan
Pages: 789-798
Published online on: 01 October 2009

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Article

Differential expression of the LOX family genes in human colorectal adenocarcinomas

Youngho Kim, Seonae Roh, Jung-Young Park, Yangsik Kim, Dong Hyung Cho, Jin Cheon Kim
Pages: 799-804
Published online on: 01 October 2009

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Article Open Access

Gene expression profile of residual breast cancer after doxorubicin and cyclophosphamide neoadjuvant chemotherapy

Maria Aparecida Azevedo Koike Folgueira, Helena Brentani, Dirce Maria Carraro, Mateus De Camargo Barros Filho, Maria Lucia Hirata Katayama, Ana Paula Santana de Abreu, Edson Mantovani Barbosa, Célia Tosello De Oliveira, Diogo F.C. Patrão, Louise D. Mota, Mario Mourão Netto, José Roberto Figaro Caldeira, Maria Mitzi Brentani
Pages: 805-813
Published online on: 01 October 2009

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Article

Potential role of Notch1 signaling pathway in laryngeal squamous cell carcinoma cell line Hep-2 involving proliferation inhibition, cell cycle arrest, cell apoptosis, and cell migration

Jing Jiao, Zhaobing Qin, Sha Li, Hongtao Liu, Zhaoming Lu
Pages: 815-823
Published online on: 01 October 2009

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Article

Norepinephrine-induced invasion by pancreatic cancer cells is inhibited by propranolol

Kun Guo, Qingyong Ma, Liancai Wang, Hengtong Hu, Junhui Li, Dong Zhang, Min Zhang
Pages: 825-830
Published online on: 01 October 2009

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Article

MycN is a transcriptional regulator of livin in neuroblastoma

Anindya Dasgupta, Susan K. Peirce, Harry W. Findley
Pages: 831-835
Published online on: 01 October 2009

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Article

FoxO3a gene is a target of deletion in mouse lung adenocarcinoma

Christopher R. Herzog, Daniel C. Blake, Oliver R. Mikse, Lubov S. Grigoryeva, Erica L. Gundermann
Pages: 837-843
Published online on: 01 October 2009

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Article

In vitro anti-neoplastic activity of the ethno-pharmaceutical plant Hypericum adenotrichum Spach endemic to Western Turkey

Ali Özmen, Sabine Bauer, Manuela Gridling, Judith Singhuber, Stanimira Krasteva, Sibylle Madlener, Than Phuong Nha Vo, Nicole Stark, Philipp Saiko, Monika Fritzer-Szekeres, Thomas Szekeres, Tülay Askin-Celik, Liselotte Krenn, Georg Krupitza
Pages: 845-852
Published online on: 01 October 2009

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Article

Identification of candidate epigenetic biomarkers for ovarian cancer detection

Yi-Wen Huang, Rachel A. Jansen, Enrica Fabbri, Dustin Potter, Sandya Liyanarachchi, Michael W.Y. Chan, Joseph C. Liu, Anne P.G. Crijns, Robert Brown, Kenneth P. Nephew, Ate G.J. van der Zee, David E. Cohn, Pearlly S. Yan, Tim H.-M. Huang, Huey-Jen L. Lin
Pages: 853-861
Published online on: 01 October 2009

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Article

Identification of specific microRNAs responding to low and high dose γ-irradiation in the human lymphoblast line IM9

Hwa Jun Cha, Ki Moon Seong, Seunghee Bae, Jin Hyuk Jung, Cha Soon Kim, Kwang-Hee Yang, Young-Woo Jin, Sungkwan An
Pages: 863-868
Published online on: 01 October 2009

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Article

Increased sensitivity to platinating agents and arsenite in human ovarian cancer by downregulation of ASNA1

Oskar Hemmingsson, Mikael Nöjd, Gautam Kao, Peter Naredi
Pages: 869-875
Published online on: 01 October 2009

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Article

A pilot study of Auron Misheil Therapy in patients with advanced cervical cancer: Tumor response and its correlation with clinical benefit response, and preliminary quality of life data

Jürgen Scheele, Faiz Niazi, Joachim Drevs, Klaus Diergarten, Papa Toure
Pages: 877-883
Published online on: 01 October 2009

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Article

Long-term results of radiofrequency ablation in colorectal lung metastases: Single center experience

Koichiro Yamakado, Yasuhiro Inoue, Motoshi Takao, Haruyuki Takaki, Atsuhiro Nakatsuka, Junji Uraki, Masataka Kashima, Masato Kusunoki, Hideto Shimpo, Kan Takeda
Pages: 885-891
Published online on: 01 October 2009

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Article

Efficacy of hybrid 2-port hand-assisted laparoscopic surgery (Mukai's operation) for patients with primary colorectal cancer

Masaya Mukai, Kyoko Kishima, Takayuki Tajima, Tatsuhiko Hoshikawa, Naoki Yazawa, Hiroshi Fukumitsu, Kazutake Okada, Kyouji Ogoshi, Hiroyasu Makuuchi
Pages: 893-899
Published online on: 01 October 2009

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Article

Microdissection is essential for gene expression analysis of irradiated rectal cancer tissues

Yasuhiro Inoue, Koji Tanaka, Takeshi Yokoe, Susumu Saigusa, Yuji Toiyama, Chikao Miki, Masato Kusunoki
Pages: 901-906
Published online on: 01 October 2009

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Article

Underexpression of PPARγ is associated with aneuploidy and lower differentiation of thyroid tumours of follicular origin

Carla Espadinha, António E. Pinto, Valeriano Leite
Pages: 907-913
Published online on: 01 October 2009

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Article

The antitumor immune responses induced by nanoemulsion-encapsulated MAGE1-HSP70/SEA complex protein vaccine following different administration routes

Wei Ge, Pei-Zhen Hu, Yang Huang, Xiao-Ming Wang, Xiu-Min Zhang, Yu-Jing Sun, Zeng-Shan Li, Shao-Yan Si, Yan-Fang Sui
Pages: 915-920
Published online on: 01 October 2009

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Article

Facilitation of drug resistance development by γ-irradiation in human cancer cells

Tsun Yee Tsang, Sze Wing Tsang, Ka Po Lai, Wing Pui Tsang, Ngai Na Co, Tim Tak Kwok
Pages: 921-926
Published online on: 01 October 2009

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Article

Clues pointing to simple hysterectomy to treat early-stage cervical cancer

Charles Coutant, Anne Gaël Cordier, Eric Guillo, Marcos Ballester, Roman Rouzier, Emile Daraï
Pages: 927-934
Published online on: 01 October 2009

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Article Open Access

Toll-like receptor 9 agonist inhibits ERα-mediated transactivation by activating NF-κB in breast cancer cell lines

Jianming Qiu, Xiaojian Wang, Xinhai Guo, Chenyin Zhao, Xuhui Wu, Yongkui Zhang
Pages: 935-941
Published online on: 01 October 2009

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Article

American ginseng berry enhances chemopreventive effect of 5-FU on human colorectal cancer cells

Xiao-Li Li, Chong-Zhi Wang, Shi Sun, Sangeeta R. Mehendale, Wei Du, Tong-Chuan He, Chun-Su Yuan
Pages: 943-952
Published online on: 01 October 2009

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Article

Human HSP70 and modified HPV16 E7 fusion DNA vaccine induces enhanced specific CD8+ T cell responses and anti-tumor effects

Jinbao Zong, Qinglin Peng, Qingyong Wang, Ting Zhang, Dongsheng Fan, Xuemei Xu
Pages: 953-961
Published online on: 01 October 2009

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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