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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2006 Volume 28 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Susceptibility of human breast epithelial cells in vitro to hormones and drugs

Gloria M. Calaf
Pages: 285-295
Published online on: 01 February 2006

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Article

Usefulness and clinical significance of quantitative real-time RT-PCR to detect isolated tumor cells in the peripheral blood and tumor drainage blood of patients with colorectal cancer

Hisae Iinuma, Kota Okinaga, Hiroshi Egami, Koshi Mimori, Naoko Hayashi, Koujiro Nishida, Miki Adachi, Masaki Mori, Mitsuru Sasako
Pages: 297-306
Published online on: 01 February 2006

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Article

Expression of keratinocyte growth factor receptor correlates with expansive growth and early stage of gastric cancer

Tetsuro Matsunobu, Toshiyuki Ishiwata, Masanori Yoshino, Masanori Watanabe, Mitsuhiro Kudo, Koshi Matsumoto, Akira Tokunaga, Takashi Tajiri, Zenya Naito
Pages: 307-314
Published online on: 01 February 2006

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Article

Protein expression of the chemokine, CCL28, in human colorectal cancer

Jan Dimberg, Anders Hugander, Dick Wågsäter
Pages: 315-319
Published online on: 01 February 2006

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Article

Homozygous deletion and reduced expression of the DOCK8 gene in human lung cancer

Kenji Takahashi, Takashi Kohno, Rieko Ajima, Hiroki Sasaki, John D. Minna, Toshiyoshi Fujiwara, Noriaki Tanaka, Jun Yokota
Pages: 321-328
Published online on: 01 February 2006

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Article

Coexpression of the IGF-IR, EGFR and HER-2 is common in colorectal cancer patients

Matthew P. Cunningham, Sharadah Essapen, Hilary Thomas, Margaret Green, David P. Lovell, Clare Topham, Christopher Marks, Helmout Modjtahedi
Pages: 329-335
Published online on: 01 February 2006

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Article

Estradiol and nicotine exposure enhances A549 bronchioloalveolar carcinoma xenograft growth in mice through the stimulation of angiogenesis

Michael J. Jarzynka, Ping Guo, Ifat Bar-Joseph, Bo Hu, Shi-Yuan Cheng
Pages: 337-344
Published online on: 01 February 2006

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Article

Macrophage migration inhibitory factor protein and mRNA expression in cutaneous melanocytic tumours

Clelia Miracco, Maria Caterina De Nisi, Felice Arcuri, Elena Cosci, Lorenzo Pacenti, Marzia Toscano, Anna Vittoria Lalinga, Maurizio Biagioli, Pietro Rubegni, Rosella Vatti, Emilia Maellaro, Barbara Del Bello, Daniela Massi, Pietro Luzi, Piero Tosi
Pages: 345-352
Published online on: 01 February 2006

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Article

Intratumoral genetic heterogeneity in pilocytic astrocytomas revealed by CGH-analysis of microdissected tumor cells and FISH on tumor tissue sections

Silke Wemmert, Bernd F.M. Romeike, Ralf Ketter, Wolf-Ingo Steudel, Klaus D. Zang, Steffi Urbschat
Pages: 353-360
Published online on: 01 February 2006

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Article

Potent anti-tumor and prolonged survival effects of E. coli-derived non-glycosylated kringle domain of tissue-type plasminogen activator

Byoung-Hak Kang, Byoung-Shik Shim, Soo Young Lee, Suk-Keun Lee, Yong-Kil Hong, Young Ae Joe
Pages: 361-367
Published online on: 01 February 2006

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Article

Analysis of the invasion-metastasis mechanism in pancreatic cancer: Involvement of plasmin(ogen) cascade proteins in the invasion of pancreatic cancer cells

Xiaodong Tan, Hiroshi Egami, Fumiaki Nozawa, Michio Abe, Hideo Baba
Pages: 369-374
Published online on: 01 February 2006

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Article

Clinical significance of class III β-tubulin expression and its predictive value for resistance to docetaxel-based chemotherapy in gastric cancer

Naomi Urano, Yoshiyuki Fujiwara, Yuichiro Doki, S. J. Kim, Yasuo Miyoshi, Shinzaburo Noguchi, Hiroshi Miyata, Shuji Takiguchi, Takushi Yasuda, Masahiko Yano, Morito Monden
Pages: 375-381
Published online on: 01 February 2006

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Article

Central genetic alterations common to all HCV-positive, HBV-positive and non-B, non-C hepatocellular carcinoma: A new approach to identify novel tumor markers

Yukinori Kurokawa, Kimi Honma, Ichiro Takemasa, Shoji Nakamori, Hiroko Kita-Matsuo, Masaaki Motoori, Hiroaki Nagano, Keizo Dono, Takahiro Ochiya, Morito Monden, Kikuya Kato
Pages: 383-391
Published online on: 01 February 2006

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Article

Hepsin shows inhibitory effects through apoptotic pathway on ovarian cancer cell lines

Keiichiro Nakamura, Yasutomo Nasu, Atsushi Hongo, Tamaki Matsuo, Junichi Kodama, Shin Ebara, Atsushi Nagai, Fernando Abrzua, Hiromi Kumon, Yuji Hiramatsu
Pages: 393-398
Published online on: 01 February 2006

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Article

Genomic signature induced by pregnancy in the human breast

Gabriela A. Balogh, Rebecca Heulings, Daniel A. Mailo, Patricia A. Russo, Fathima Sheriff, Irma H. Russo, Raquel Moral, Jose Russo
Pages: 399-410
Published online on: 01 February 2006

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Article

Molecular detection of circulating cancer cells in the peripheral blood of patients with colorectal cancer by using membrane array with a multiple mRNA marker panel

Ching-Sheng Yeh, Jaw-Yuan Wang, Chan-Han Wu, Inn-Wen Chong, Fu-Yen Chung, Yung-Hsin Wang, Ya-Ping Yu, Shiu-Ru Lin
Pages: 411-420
Published online on: 01 February 2006

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Article

Monoclonal antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2 (TRAIL-R2) induces apoptosis in primary renal cell carcinoma cells in vitro and inhibits tumor growth in vivo

Y. Zeng, X. X. Wu, M. Fiscella, O. Shimada, R. Humphreys, V. Albert, Y. Kakehi
Pages: 421-430
Published online on: 01 February 2006

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Article

T-cell response to p53 tumor-associated antigen in patients with colorectal carcinoma

Marco Bueter, Martin Gasser, Nicolai Schramm, Tatiana Lebedeva, Georges Tocco, Christiane Gerstlauer, Martin Grimm, Ekaterina Nichiporuk, Andreas Thalheimer, Arnulf Thiede, Detlef Meyer, Gilles Benichou, Ana Maria Waaga-Gasser
Pages: 431-438
Published online on: 01 February 2006

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Article

Anti-cancer effects of bortezomib against chemoresistant neuroblastoma cell lines in vitro and in vivo

Martin Michaelis, Iduna Fichtner, Diana Behrens, Wolfram Haider, Florian Rothweiler, Andreas Mack, Jaroslav Cinatl, Hans Wilhelm Doerr, Jindrich Cinatl
Pages: 439-446
Published online on: 01 February 2006

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Article

Chromosomal organization and fluorescence in situ hybridization of the human Sirtuin 6 gene

Ulrich Mahlknecht, Anthony D. Ho, Susanne Voelter-Mahlknecht
Pages: 447-456
Published online on: 01 February 2006

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Article

Delivery of the bacterial nitroreductase gene into endothelial cells prolongs the survival of tumour-bearing mice by bystander mechanisms

Malika Benouchan, Filipe Do Nascimento, Gérard Y. Perret, Bruno M. Colombo
Pages: 457-462
Published online on: 01 February 2006

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Article

Identification of a novel SEREX antigen, SLC2A1/GLUT1, in esophageal squamous cell carcinoma

Mari Kuboshima, Hideaki Shimada, Tian-Ling Liu, Kazue Nakashima, Fumio Nomura, Masaki Takiguchi, Takaki Hiwasa, Takenori Ochiai
Pages: 463-468
Published online on: 01 February 2006

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Article

GTI-2501, an antisense agent targeting R1, the large subunit of human ribonucleotide reductase, shows potent anti-tumor activity against a variety of tumors

Yoon Lee, Aikaterini Vassilakos, Ningping Feng, Hongnan Jin, Ming Wang, Keyong Xiong, Jim Wright, Aiping Young
Pages: 469-478
Published online on: 01 February 2006

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Article

in vitro synergistic antitumor activity of a combination of 5-fluorouracil and irinotecan in human colon cancer

Yasuhiro Inoue, Koji Tanaka, Junichiro Hiro, Shigeyuki Yoshiyama, Yuji Toiyama, Tomoya Eguchi, Chikao Miki, Masato Kusunoki
Pages: 479-486
Published online on: 01 February 2006

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Article

Involvement of Ets-1 transcription factor in inducing matrix metalloproteinase-2 expression by epithelial-mesenchymal transition in human squamous carcinoma cells

Masayuki Taki, Kristin Verschueren, Kazuhiro Yokoyama, Masaru Nagayama, Nobuyuki Kamata
Pages: 487-496
Published online on: 01 February 2006

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Article

A novel mechanism for acquired cisplatin-resistance: Suppressed translation of death-associated protein kinase mRNA is insensitive to 5-aza-2'-deoxycitidine and trichostatin in cisplatin-resistant cervical squamous cancer cells

Tao Bai, Tetsuji Tanaka, Kazunori Yukawa, Naohiko Umesaki
Pages: 497-508
Published online on: 01 February 2006

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Article

Pooled analysis of two case-control studies on the use of cellular and cordless telephones and the risk of benign brain tumours diagnosed during 1997-2003

Lennart Hardell, Michael Carlberg, Kjell Hansson Mild
Pages: 509-518
Published online on: 01 February 2006

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Review

Influence of p53 on anti-tumor immunity (Review)

Marco Bueter, Martin Gasser, Tatiana Lebedeva, Gilles Benichou, Ana Maria Waaga-Gasser
Pages: 519-525
Published online on: 01 February 2006

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Article

Molecular factors of 5-fluorouracil metabolism in colorectal cancer: Analysis of primary tumor and lymph node metastasis

D. Vallböhmer, H. Kuramochi, D. Shimizu, K. D. Danenberg, J. Lindebjerg, J. N. Nielsen, A. Jakobsen, P. V. Danenberg
Pages: 527-533
Published online on: 01 February 2006

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Article

Down-regulation of FAK and IAPs by laminin during cisplatin-induced apoptosis in testicular germ cell tumors

Maoulana Andjilani, Jean-Pierre Droz, Mohamed Benahmed, Eric Tabone
Pages: 535-542
Published online on: 01 February 2006

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Article

Cyclooxygenase-2 knockdown by RNA interference in colon cancer

George S. Charames, Bharati Bapat
Pages: 543-549
Published online on: 01 February 2006

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Article

Glucocorticoid-mediated inhibition of chemotherapy in ovarian carcinomas

Chengwen Zhang, Alexander Marmé, Till Wenger, Paul Gutwein, Lutz Edler, Werner Rittgen, Klaus-Michael Debatin, Peter Altevogt, Jürgen Mattern, Ingrid Herr
Pages: 551-558
Published online on: 01 February 2006

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Article

Characterization of four clones derived from human adenocarcinoma cell line, HT29, and analysis of their response to sodium butyrate

Jitka Stokrová, Eva Sloncová, Vlasta Sovová, Dana Kucerová, Vojtech Zíla, Jolana Turecková, Martina Vojtechová, Jan Korb, Zdena Tuhácková
Pages: 559-565
Published online on: 01 February 2006

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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