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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2006 Volume 28 Issue 2

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Susceptibility of human breast epithelial cells in vitro to hormones and drugs

Gloria M. Calaf
Pages: 285-295
Published online on: 01 February 2006

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Article

Usefulness and clinical significance of quantitative real-time RT-PCR to detect isolated tumor cells in the peripheral blood and tumor drainage blood of patients with colorectal cancer

Hisae Iinuma, Kota Okinaga, Hiroshi Egami, Koshi Mimori, Naoko Hayashi, Koujiro Nishida, Miki Adachi, Masaki Mori, Mitsuru Sasako
Pages: 297-306
Published online on: 01 February 2006

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Article

Expression of keratinocyte growth factor receptor correlates with expansive growth and early stage of gastric cancer

Tetsuro Matsunobu, Toshiyuki Ishiwata, Masanori Yoshino, Masanori Watanabe, Mitsuhiro Kudo, Koshi Matsumoto, Akira Tokunaga, Takashi Tajiri, Zenya Naito
Pages: 307-314
Published online on: 01 February 2006

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Article

Protein expression of the chemokine, CCL28, in human colorectal cancer

Jan Dimberg, Anders Hugander, Dick Wågsäter
Pages: 315-319
Published online on: 01 February 2006

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Article

Homozygous deletion and reduced expression of the DOCK8 gene in human lung cancer

Kenji Takahashi, Takashi Kohno, Rieko Ajima, Hiroki Sasaki, John D. Minna, Toshiyoshi Fujiwara, Noriaki Tanaka, Jun Yokota
Pages: 321-328
Published online on: 01 February 2006

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Article

Coexpression of the IGF-IR, EGFR and HER-2 is common in colorectal cancer patients

Matthew P. Cunningham, Sharadah Essapen, Hilary Thomas, Margaret Green, David P. Lovell, Clare Topham, Christopher Marks, Helmout Modjtahedi
Pages: 329-335
Published online on: 01 February 2006

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Article

Estradiol and nicotine exposure enhances A549 bronchioloalveolar carcinoma xenograft growth in mice through the stimulation of angiogenesis

Michael J. Jarzynka, Ping Guo, Ifat Bar-Joseph, Bo Hu, Shi-Yuan Cheng
Pages: 337-344
Published online on: 01 February 2006

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Article

Macrophage migration inhibitory factor protein and mRNA expression in cutaneous melanocytic tumours

Clelia Miracco, Maria Caterina De Nisi, Felice Arcuri, Elena Cosci, Lorenzo Pacenti, Marzia Toscano, Anna Vittoria Lalinga, Maurizio Biagioli, Pietro Rubegni, Rosella Vatti, Emilia Maellaro, Barbara Del Bello, Daniela Massi, Pietro Luzi, Piero Tosi
Pages: 345-352
Published online on: 01 February 2006

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Article

Intratumoral genetic heterogeneity in pilocytic astrocytomas revealed by CGH-analysis of microdissected tumor cells and FISH on tumor tissue sections

Silke Wemmert, Bernd F.M. Romeike, Ralf Ketter, Wolf-Ingo Steudel, Klaus D. Zang, Steffi Urbschat
Pages: 353-360
Published online on: 01 February 2006

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Article

Potent anti-tumor and prolonged survival effects of E. coli-derived non-glycosylated kringle domain of tissue-type plasminogen activator

Byoung-Hak Kang, Byoung-Shik Shim, Soo Young Lee, Suk-Keun Lee, Yong-Kil Hong, Young Ae Joe
Pages: 361-367
Published online on: 01 February 2006

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Article

Analysis of the invasion-metastasis mechanism in pancreatic cancer: Involvement of plasmin(ogen) cascade proteins in the invasion of pancreatic cancer cells

Xiaodong Tan, Hiroshi Egami, Fumiaki Nozawa, Michio Abe, Hideo Baba
Pages: 369-374
Published online on: 01 February 2006

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Article

Clinical significance of class III β-tubulin expression and its predictive value for resistance to docetaxel-based chemotherapy in gastric cancer

Naomi Urano, Yoshiyuki Fujiwara, Yuichiro Doki, S. J. Kim, Yasuo Miyoshi, Shinzaburo Noguchi, Hiroshi Miyata, Shuji Takiguchi, Takushi Yasuda, Masahiko Yano, Morito Monden
Pages: 375-381
Published online on: 01 February 2006

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Article

Central genetic alterations common to all HCV-positive, HBV-positive and non-B, non-C hepatocellular carcinoma: A new approach to identify novel tumor markers

Yukinori Kurokawa, Kimi Honma, Ichiro Takemasa, Shoji Nakamori, Hiroko Kita-Matsuo, Masaaki Motoori, Hiroaki Nagano, Keizo Dono, Takahiro Ochiya, Morito Monden, Kikuya Kato
Pages: 383-391
Published online on: 01 February 2006

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Article

Hepsin shows inhibitory effects through apoptotic pathway on ovarian cancer cell lines

Keiichiro Nakamura, Yasutomo Nasu, Atsushi Hongo, Tamaki Matsuo, Junichi Kodama, Shin Ebara, Atsushi Nagai, Fernando Abrzua, Hiromi Kumon, Yuji Hiramatsu
Pages: 393-398
Published online on: 01 February 2006

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Article

Genomic signature induced by pregnancy in the human breast

Gabriela A. Balogh, Rebecca Heulings, Daniel A. Mailo, Patricia A. Russo, Fathima Sheriff, Irma H. Russo, Raquel Moral, Jose Russo
Pages: 399-410
Published online on: 01 February 2006

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Article

Molecular detection of circulating cancer cells in the peripheral blood of patients with colorectal cancer by using membrane array with a multiple mRNA marker panel

Ching-Sheng Yeh, Jaw-Yuan Wang, Chan-Han Wu, Inn-Wen Chong, Fu-Yen Chung, Yung-Hsin Wang, Ya-Ping Yu, Shiu-Ru Lin
Pages: 411-420
Published online on: 01 February 2006

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Article

Monoclonal antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2 (TRAIL-R2) induces apoptosis in primary renal cell carcinoma cells in vitro and inhibits tumor growth in vivo

Y. Zeng, X. X. Wu, M. Fiscella, O. Shimada, R. Humphreys, V. Albert, Y. Kakehi
Pages: 421-430
Published online on: 01 February 2006

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Article

T-cell response to p53 tumor-associated antigen in patients with colorectal carcinoma

Marco Bueter, Martin Gasser, Nicolai Schramm, Tatiana Lebedeva, Georges Tocco, Christiane Gerstlauer, Martin Grimm, Ekaterina Nichiporuk, Andreas Thalheimer, Arnulf Thiede, Detlef Meyer, Gilles Benichou, Ana Maria Waaga-Gasser
Pages: 431-438
Published online on: 01 February 2006

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Article

Anti-cancer effects of bortezomib against chemoresistant neuroblastoma cell lines in vitro and in vivo

Martin Michaelis, Iduna Fichtner, Diana Behrens, Wolfram Haider, Florian Rothweiler, Andreas Mack, Jaroslav Cinatl, Hans Wilhelm Doerr, Jindrich Cinatl
Pages: 439-446
Published online on: 01 February 2006

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Article

Chromosomal organization and fluorescence in situ hybridization of the human Sirtuin 6 gene

Ulrich Mahlknecht, Anthony D. Ho, Susanne Voelter-Mahlknecht
Pages: 447-456
Published online on: 01 February 2006

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Article

Delivery of the bacterial nitroreductase gene into endothelial cells prolongs the survival of tumour-bearing mice by bystander mechanisms

Malika Benouchan, Filipe Do Nascimento, Gérard Y. Perret, Bruno M. Colombo
Pages: 457-462
Published online on: 01 February 2006

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Article

Identification of a novel SEREX antigen, SLC2A1/GLUT1, in esophageal squamous cell carcinoma

Mari Kuboshima, Hideaki Shimada, Tian-Ling Liu, Kazue Nakashima, Fumio Nomura, Masaki Takiguchi, Takaki Hiwasa, Takenori Ochiai
Pages: 463-468
Published online on: 01 February 2006

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Article

GTI-2501, an antisense agent targeting R1, the large subunit of human ribonucleotide reductase, shows potent anti-tumor activity against a variety of tumors

Yoon Lee, Aikaterini Vassilakos, Ningping Feng, Hongnan Jin, Ming Wang, Keyong Xiong, Jim Wright, Aiping Young
Pages: 469-478
Published online on: 01 February 2006

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Article

in vitro synergistic antitumor activity of a combination of 5-fluorouracil and irinotecan in human colon cancer

Yasuhiro Inoue, Koji Tanaka, Junichiro Hiro, Shigeyuki Yoshiyama, Yuji Toiyama, Tomoya Eguchi, Chikao Miki, Masato Kusunoki
Pages: 479-486
Published online on: 01 February 2006

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Article

Involvement of Ets-1 transcription factor in inducing matrix metalloproteinase-2 expression by epithelial-mesenchymal transition in human squamous carcinoma cells

Masayuki Taki, Kristin Verschueren, Kazuhiro Yokoyama, Masaru Nagayama, Nobuyuki Kamata
Pages: 487-496
Published online on: 01 February 2006

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Article

A novel mechanism for acquired cisplatin-resistance: Suppressed translation of death-associated protein kinase mRNA is insensitive to 5-aza-2'-deoxycitidine and trichostatin in cisplatin-resistant cervical squamous cancer cells

Tao Bai, Tetsuji Tanaka, Kazunori Yukawa, Naohiko Umesaki
Pages: 497-508
Published online on: 01 February 2006

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Article

Pooled analysis of two case-control studies on the use of cellular and cordless telephones and the risk of benign brain tumours diagnosed during 1997-2003

Lennart Hardell, Michael Carlberg, Kjell Hansson Mild
Pages: 509-518
Published online on: 01 February 2006

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Review

Influence of p53 on anti-tumor immunity (Review)

Marco Bueter, Martin Gasser, Tatiana Lebedeva, Gilles Benichou, Ana Maria Waaga-Gasser
Pages: 519-525
Published online on: 01 February 2006

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Article

Molecular factors of 5-fluorouracil metabolism in colorectal cancer: Analysis of primary tumor and lymph node metastasis

D. Vallböhmer, H. Kuramochi, D. Shimizu, K. D. Danenberg, J. Lindebjerg, J. N. Nielsen, A. Jakobsen, P. V. Danenberg
Pages: 527-533
Published online on: 01 February 2006

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Article

Down-regulation of FAK and IAPs by laminin during cisplatin-induced apoptosis in testicular germ cell tumors

Maoulana Andjilani, Jean-Pierre Droz, Mohamed Benahmed, Eric Tabone
Pages: 535-542
Published online on: 01 February 2006

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Article

Cyclooxygenase-2 knockdown by RNA interference in colon cancer

George S. Charames, Bharati Bapat
Pages: 543-549
Published online on: 01 February 2006

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Article

Glucocorticoid-mediated inhibition of chemotherapy in ovarian carcinomas

Chengwen Zhang, Alexander Marmé, Till Wenger, Paul Gutwein, Lutz Edler, Werner Rittgen, Klaus-Michael Debatin, Peter Altevogt, Jürgen Mattern, Ingrid Herr
Pages: 551-558
Published online on: 01 February 2006

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Article

Characterization of four clones derived from human adenocarcinoma cell line, HT29, and analysis of their response to sodium butyrate

Jitka Stokrová, Eva Sloncová, Vlasta Sovová, Dana Kucerová, Vojtech Zíla, Jolana Turecková, Martina Vojtechová, Jan Korb, Zdena Tuhácková
Pages: 559-565
Published online on: 01 February 2006

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Journal Cover
October-2026 Volume 69 Issue 4

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

MicroRNA regulation of macrophage polarization in lung cancer: Regulatory networks and therapeutic potential (Review)

Zhao Yiming, Li Jie
Article Number: 121
Published online on: 02 September 2026

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Article Open Access

Effect of xeroderma pigmentosum group C on the characteristics and regulatory mechanisms of lung cancer stem cells

Ben Yang, Yang Yang, Weiyu Wang, Yubing Wang, Huaijie Wang, Liya Qin, Yongming Wang, Sipeng Sun, Shubo Wang, Meihua Qu
Article Number: 120
Published online on: 01 September 2026

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Review Open Access

Post‑translational modification‑governed immune states in cancer immunity: Biomarker implications for checkpoint competence, tumor visibility and immunotherapy resistance (Review)

Jinghao Pan, Boyang Li, Ruonan Lin, Chenlu Fang, Lucy Yue Lau, Zehao Hong, Yi Chen
Article Number: 119
Published online on: 21 August 2026

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Correction Open Access

[Corrigendum] Sulforaphane reduces molecular response to hypoxia in ovarian tumor cells independently of their resistance to chemotherapy

Michal Pastorek, Veronika Simko, Martina Takacova, Monika Barathova, Maria Bartosova, Luba Hunakova, Olga Sedlakova, Sona Hudecova, Olga Krizanova, Franck Dequiedt, Silvia Pastorekova, Jan Sedlak
Article Number: 118
Published online on: 20 August 2026

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Article Open Access

Single in situ intratumoral low‑dose shikonin hydrogel plus mild photothermal therapy elicits systemic antitumor immunity in immune‑cold triple‑negative breast cancer

Tao Pan, Zujian Feng, Ting Shang, Jun Jiang, Fang Zhang
Article Number: 117
Published online on: 19 August 2026

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Article Open Access

KIAA1429 knockdown alleviates osteosarcoma  progression by destabilizing SLC7A11 mRNA via m6A methylation to promote ferroptosis

Hui Zeng, Yunyan Zhong, Dingbiao Zeng, Shiliang Xiao, Song Zou
Article Number: 116
Published online on: 17 August 2026

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Correction Open Access

[Corrigendum] Tanshinone I effectively induces apoptosis in estrogen receptor‑positive (MCF‑7) and estrogen receptor‑negative (MDA‑MB‑231) breast cancer cells

Irina Tsoy Nizamutdinova, Gyeong Won Lee, Kun Ho Son, Su Jin Jeon, Sam Sik Kang, Yeong Shik Kim, Jae Heun Lee, Han Geuk Seo, Ki Churl Chang, Hye Jung Kim
Article Number: 115
Published online on: 12 August 2026

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Review Open Access

Signaling pathways and targeted therapy in high‑risk refractory thyroid cancer: From bench to bedside (Review)

Jian Wang, Zhi Liu, Qing Zhang, Wei Sun
Article Number: 114
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Downmodulation of dimethyl transferase activity enhances tumor necrosis factor‑related apoptosis‑inducing ligand‑ induced apoptosis in prostate cancer cells

Claudio Festuccia, Giovanni Luca Gravina, Anna Maria D'Alessandro, Danilo Millimaggi, Cristiana Di Rocco, Vincenza Dolo, Enrico Ricevuto, Carlo Vicentini, Mauro Bologna
Article Number: 113
Published online on: 10 August 2026

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Review Open Access

The pivotal role of SCD1 in digestive cancers: Bridging lipid metabolic reprogramming and programmed cell death (Review)

Yangxi Fu, Zheng Wang, Lin Liu, Xudong Tang
Article Number: 112
Published online on: 07 August 2026

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Article Open Access

piR‑164552 promotes malignant progression in head and neck squamous cell carcinoma via the RBM4/EIF4E2 signaling axis: Insights from multi‑omics and functional analyses

Shan Yang, Zhen Shang, Shunxian Xia, Hongbo Liu, Yanhan Dong, Xiaomin Wang, Wenhua Xu, Haijun Lu
Article Number: 111
Published online on: 07 August 2026

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Correction Open Access

[Corrigendum] Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines

Nesstor Pilco‑Ferreto, Gloria   M. Calaf
Article Number: 110
Published online on: 20 July 2026

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Article Open Access

Evaluation of Punicalagin as a multi‑targeted therapeutic agent against endometrial cancer

Zeeshan Ahmad Bhutta, Dohee Ahn, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 109
Published online on: 17 July 2026

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Journal Cover
November-2026 Volume 69 Issue 5

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Eomesodermin in renal cell carcinoma: Epigenetic and immune crosstalk driving tumor progression (Review)

Zhifei Che, Dongwen Huang, Jiaming Lin, Xincen Wang, Rongjin Feng, Xianping Che, Yubin Wang
Article Number: 128
Published online on: 18 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ultraviolet exposure of melanoma cells induces fibroblast activation protein‑α in fibroblasts: Implications for melanoma invasion

Petra Wäster, Inger Rosdahl, Brendan F.  Gilmore, Oliver Seifert
Article Number: 127
Published online on: 16 September 2026

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Article Open Access

E3 ubiquitin ligase MAGI3‑mediated TAZ ubiquitination suppresses the non‑small cell lung cancer occurrence and development by targeting the Wnt pathway

Ye Liang, Jie Zhuang
Article Number: 126
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] TIP60 governs the auto‑ubiquitination of UHRF1 through USP7 dissociation from the UHRF1/USP7 complex

Tanveer Ahmad, Waseem Ashraf, Abdulkhaleg Ibrahim, Liliyana Zaayter, Christian D. Muller, Ali Hamiche, Yves Mély, Christian Bronner, Marc Mousli
Article Number: 125
Published online on: 14 September 2026

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Correction Open Access

[Corrigendum] miR‑221/222 promote malignant progression of glioma through activation of the Akt pathway

Junxia Zhang, Lei Han, Youlin Ge, Xuan Zhou, Anling Zhang, Chunzhi Zhang, Yue Zhong, Yongping You, Peiyu Pu, Chunsheng Kang
Article Number: 124
Published online on: 03 September 2026

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Review Open Access

Dendritic cell‑based vaccines for colorectal cancer: Mechanisms, clinical progress and future directions (Review)

Lian Yih Pong, Siti Ayuni Hassanudin, Seng Kong Tham, Ravichandran Manickam, Chee Yin Wong, Keat Seong Poh, Chit Laa Poh
Article Number: 123
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Pro‑metastatic intracellular signaling of the elaidic trans fatty acid

Kiyomu Fujii, Yi Luo, Rina Fujiwara-tani, Shingo Kishi, Song He, Shuyun Yang, Takamitsu Sasaki, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 122
Published online on: 02 September 2026

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