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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2010 Volume 37 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Inter-related in vitro effects of androgens, fatty acids and oxidative stress in prostate cancer: A mechanistic model supporting prevention strategies

Helen Lin, Jian-Ping Lu, Pierre Laflamme, Shengjun Qiao, Bobby Shayegan, Inna Bryskin, Lauren Monardo, Brian C. Wilson, Gurmit Singh, Jehonathan H. Pinthus
Pages: 761-766
Published online on: 01 October 2010

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Article

Effects of vandetanib on adenoma formation in a dextran sodium sulphate enhanced ApcMIN/+ mouse model

Denis G. Alferez, Anderson J. Ryan, Robert A. Goodlad, Nick A. Wright, Robert W. Wilkinson
Pages: 767-772
Published online on: 01 October 2010

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Article Open Access

Novel bladder preservation therapy for locally invasive bladder cancer: Combined therapy using balloon-occluded arterial infusion of anticancer agent and hemodialysis with concurrent radiation

Haruhito Azuma, Teruo Inamoto, Naokazu Ibuki, Takanobu Ubai, Yatsugu Kotake, Kiyoshi Takahara, Satoshi Kiyama, Hayahito Nomi, Hiroshi Uehara, Kazumasa Komura, Kazuhiro Yamamoto, Yoshihumi Narumi, Yoji Katsuoka
Pages: 773-785
Published online on: 01 October 2010

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Article

Histone deacetylase inhibitors valproic acid and depsipeptide sensitize retinoblastoma cells to radiotherapy by increasing H2AX phosphorylation and p53 acetylation-phosphorylation

Takeshi Kawano, Masaharu Akiyama, Miyuki Agawa-Ohta, Yoko Mikami-Terao, Satsuki Iwase, Takaaki Yanagisawa, Hiroyuki Ida, Naoki Agata, Hisashi Yamada
Pages: 787-795
Published online on: 01 October 2010

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Article

Midkine expression is correlated with an adverse prognosis and is down-regulated by p53 in oral squamous cell carcinoma

Kazutoshi Ota, Hiromi Fujimori, Mitsuharu Ueda, Hirofumi Jono, Satoru Shinriki, Tomoko Ota, Takanao Sueyoshi, Manabu Taura, Ayaka Taguma, Hirofumi Kai, Masanori Shinohara, Yukio Ando
Pages: 797-804
Published online on: 01 October 2010

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Article

Functional cell surface expression of Toll-like receptor 9 promotes cell proliferation and survival in human hepatocellular carcinomas

Junichiro Tanaka, Kazushi Sugimoto, Katsuya Shiraki, Masahiko Tameda, Satoko Kusagawa, Keiichiro Nojiri, Tetsuya Beppu, Kentaro Yoneda, Norihiko Yamamoto, Kazuhiko Uchida, Takahiro Kojima, Yoshiyuki Takei
Pages: 805-814
Published online on: 01 October 2010

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Article

Clarithromycin attenuates autophagy in myeloma cells

Miki Nakamura, Yoshitaka Kikukawa, Motohiro Takeya, Hiroaki Mitsuya, Hiroyuki Hata
Pages: 815-820
Published online on: 01 October 2010

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Article

The role of autophagy in the treatment of pancreatic cancer with gemcitabine and ionizing radiation

Hideyo Mukubou, Toshiaki Tsujimura, Ryohei Sasaki, Yonson Ku
Pages: 821-828
Published online on: 01 October 2010

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Article

The use of protein array to identify targetable receptor tyrosine kinases for treatment of human colon cancer

Asahiro Morishita, Jian Gong, Takako Nomura, Hirohito Yoshida, Kunihiko Izuishi, Yasuyuki Suzuki, Yoshio Kushida, Reiji Haba, Jeanine D'Armiento, Tsutomu Masaki
Pages: 829-835
Published online on: 01 October 2010

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Article

The role of serum response factor in hepatocellular carcinoma: Implications for disease progression

Chang Young Kwon, Kyung Ryoul Kim, Ha Na Choi, Myoung Ja Chung, Sang Jae Noh, Dae Ghon Kim, Myoung Jae Kang, Dong Geun Lee, Woo Sung Moon
Pages: 837-844
Published online on: 01 October 2010

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Article

Ribonucleotide reductase subunit M1 assessed by quantitative double-fluorescence immunohistochemistry predicts the efficacy of gemcitabine in biliary tract carcinoma

Jun Nakamura, Naohiko Kohya, Keita Kai, Kazuma Ohtaka, Kazuyoshi Hashiguchi, Masatsugu Hiraki, Yoshihiko Kitajima, Osamu Tokunaga, Hirokazu Noshiro, Kohji Miyazaki
Pages: 845-852
Published online on: 01 October 2010

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Article

TC21 promotes cell motility and metastasis by regulating the expression of E-cadherin and N-cadherin in hepatocellular carcinoma

Hairong Luo, Xiangfang Hao, Chao Ge, Fangyu Zhao, Miaoxin Zhu, Taoyang Chen, Ming Yao, Xianghuo He, Jinjun Li
Pages: 853-859
Published online on: 01 October 2010

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Article

Involvement of C12orf32 overexpression in breast carcinogenesis

Jung-Won Kim, Chikako Fukukawa, Koji Ueda, Toshihiko Nishidate, Toyomasa Katagiri, Yusuke Nakamura
Pages: 861-867
Published online on: 01 October 2010

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Article

Imatinib mesylate inhibits the proliferation-stimulating effect of human lung cancer-associated stromal fibroblasts on lung cancer cells

Keiichi Kinoshita, Koji Nakagawa, Jun-Ichi Hamada, Yasuhiro Hida, Mitsuhiro Tada, Satoshi Kondo, Tetsuya Moriuchi
Pages: 869-877
Published online on: 01 October 2010

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Article

Vandetanib alters the protein pattern in malignant glioma and normal brain in the BT4C rat glioma model

Carl Wibom, Maria Sandström, Roger Henriksson, Henrik Antti, Mikael Johansson, A. Tommy Bergenheim
Pages: 879-890
Published online on: 01 October 2010

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Article

Blood monocytes from mammary tumor-bearing mice: Early targets of tumor-induced immune suppression?

Raul Caso, Risset Silvera, Roberto Carrio, Viyaya Iragavarapu-Charyulu, Ruben R. Gonzalez-Perez, Marta Torroella-Kouri
Pages: 891-900
Published online on: 01 October 2010

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Article

Medullary carcinoma of the large intestine: A population based analysis

Pragatheeshwar Thirunavukarasu, Magesh Sathaiah, Smit Singla, Shyam Sukumar, Arivarasan Karunamurthy, Kothai Divya Pragatheeshwar, Kenneth K.W. Lee, Herbert Zeh, Kevin M. Kane, David L. Bartlett
Pages: 901-907
Published online on: 01 October 2010

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Article Open Access

Palladin, an actin-associated protein, is required for adherens junction formation and intercellular adhesion in HCT116 colorectal cancer cells

Puei Nam Tay, Patrick Tan, Yuhong Lan, Carol Ho-Wing Leung, Mirtha Laban, Tze Chin Tan, Hongmin Ni, Jayapal Manikandan, Suhaimi Bin Abdul Rashid, Benedict Yan, Celestial Therese Yap, Lina Hsiu Kim Lim, Yaw Chyn Lim, Shing Chuan Hooi
Pages: 909-926
Published online on: 01 October 2010

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Article

Protective effect of the dopamine D3 receptor agonist (7-OH-PIPAT) against apoptosis in malignant peripheral nerve sheath tumor (MPNST) cells

A. Castorina, S. Giunta, V. D'Agata
Pages: 927-934
Published online on: 01 October 2010

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Article

Anti-tumor activity of gene transfer of the membrane-stable CD40L mutant into lung cancer cells

Wei Xu, Yan Li, Xueli Wang, Cuiyu Wang, Weihong Zhao, Jianqing Wu
Pages: 935-941
Published online on: 01 October 2010

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Article

TrkB antibody elicits cytotoxicity and suppresses migration/invasion of transitional cell carcinoma cells

Yen Ta Huang, Pei Chun Lai, Chia Chen Wu, Chuan Chu Cheng, Ted H. Chiu
Pages: 943-949
Published online on: 01 October 2010

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Article

P21-activated protein kinase 1 induces colorectal cancer metastasis involving ERK activation and phosphorylation of FAK at Ser-910

Liang-Hui Li, Min-Hua Zheng, Qi Luo, Qing Ye, Bo Feng, Ai-Guo Lu, Ming-Liang Wang, Xue-Hua Chen, Li-Ping Su, Bing-Ya Liu
Pages: 951-962
Published online on: 01 October 2010

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Article

Enhanced growth inhibition by combined DNA methylation/HDAC inhibitors in lung tumor cells with silenced CDKN2A

Min Chen, Donna Voeller, Victor E. Marquez, Frederic J. Kaye, Patricia S. Steeg, Giuseppe Giaccone, Maria Zajac-Kaye
Pages: 963-971
Published online on: 01 October 2010

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Article

Acacia honey and chrysin reduce proliferation of melanoma cells through alterations in cell cycle progression

Elena Pichichero, Rosella Cicconi, Maurizio Mattei, Marco Gallinella Muzi, Antonella Canini
Pages: 973-981
Published online on: 01 October 2010

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Article

Biological effects of induced MYCN hyper-expression in MYCN-amplified neuroblastomas

Jaime Torres, Paul L. Regan, Robby Edo, Payton Leonhardt, Eric I. Jeng, Eric F. Rappaport, Naohiko Ikegaki, Xao X. Tang
Pages: 983-991
Published online on: 01 October 2010

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Article

Inhibitory effects of docosyl p-coumarate on DNA topoisomerase activity and human cancer cell growth

Yoshiyuki Mizushina, Katsumi Nishimura, Yukiko Takenaka, Toshifumi Takeuchi, Fumio Sugawara, Hiromi Yoshida, Takao Tanahashi
Pages: 993-1000
Published online on: 01 October 2010

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Article

Effect of rapamycin, an mTOR inhibitor, on radiation sensitivity of lung cancer cells having different p53 gene status

Yoko Nagata, Akihisa Takahashi, Ken Ohnishi, Ichiro Ota, Takeo Ohnishi, Takashi Tojo, Shigeki Taniguchi
Pages: 1001-1010
Published online on: 01 October 2010

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Article

Resistance to chemotherapeutic agents and promotion of transforming activity mediated by embryonic stem cell-expressed Ras (ERas) signal in neuroblastoma cells

Mineyoshi Aoyama, Hiromi Kataoka, Eiji Kubota, Toyohiro Tada, Kiyofumi Asai
Pages: 1011-1016
Published online on: 01 October 2010

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Article

Death-associated protein kinase is essential for the survival of various types of uterine cancer cells

Tetsuji Tanaka, Tao Bai, Kazunori Yukawa
Pages: 1017-1022
Published online on: 01 October 2010

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Article

2-Arylthiazolidine-4-carboxylic acid amides (ATCAA) target dual pathways in cancer cells: 5'-AMP-activated protein kinase (AMPK)/mTOR and PI3K/Akt/mTOR pathways

Chien-Ming Li, Ramesh Narayanan, Yan Lu, Eunju Hurh, Christopher C. Coss, Christina M. Barrett, Duane D. Miller, James T. Dalton
Pages: 1023-1030
Published online on: 01 October 2010

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Article

Downregulation of active caspase 8 as a mechanism of acquired TRAIL resistance in mismatch repair-proficient colon carcinoma cell lines

Caroline M.M. Van Geelen, Bodvael Pennarun, Wytske Boerma-Van Ek, Phuong T.K. Le, Diana C.J. Spierings, Elisabeth G.E. De Vries, Steven De Jong
Pages: 1031-1041
Published online on: 01 October 2010

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Article

In vitro novel combinations of psychotropics and anti-cancer modalities in U87 human glioblastoma cells

Sivan Tzadok, Einat Beery, Moshe Israeli, Orit Uziel, Meir Lahav, Eyal Fenig, Irit Gil-Ad, Abraham Weizman, Jardena Nordenberg
Pages: 1043-1051
Published online on: 01 October 2010

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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